{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:03:12Z","timestamp":1760781792639},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1988,4,1]],"date-time":"1988-04-01T00:00:00Z","timestamp":575856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[1988,4]]},"DOI":"10.1007\/bf03350147","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T15:34:23Z","timestamp":1397144063000},"page":"247-253","source":"Crossref","is-referenced-by-count":8,"title":["Plasma pro-opiomelanocortin fragments and adrenal steroids following administration of metyrapone to normal and hirsute women"],"prefix":"10.1007","volume":"11","author":[{"given":"S. K.","family":"Cunningham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Loughlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Bertagna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Girard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J.","family":"McKenna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,4,9]]},"reference":[{"key":"BF03350147_CR1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1530\/acta.0.1040365","volume":"104","author":"SK Cunningham","year":"1983","unstructured":"Cunningham S.K., Loughlin T., Culliton M., McKenna T.J. Plasma sex hormone-binding globulin and androgen levels in the management of hirsute patients. Acta Endocrinol. (Kbh.) 104: 365, 1983.","journal-title":"Acta Endocrinol. (Kbh.)"},{"key":"BF03350147_CR2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1365-2265.1983.tb00584.x","volume":"18","author":"A Moore","year":"1983","unstructured":"Moore A., Magee F., Cunningham S., Culliton M., McKenna T.J. Adrenal abnormalities in idiopathic hirsutism. Clin. Endocrinol. (Oxf.) 18: 391, 1983.","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"BF03350147_CR3","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1210\/jcem-62-1-142","volume":"62","author":"T Loughlin","year":"1986","unstructured":"Loughlin T., Cunningham S., Moore A., Culliton M., Smyth P.P.A., McKenna T.J. Adrenal abnormalities in polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 62: 142, 1986.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03350147_CR4","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/0026-0495(84)90210-5","volume":"33","author":"TJ McKenna","year":"1984","unstructured":"McKenna T.J., Loughlin T., Daly L., Smyth P.P.A., Culliton M., Cunningham S. Variable clinical and hormonal manifestations of hyper-androgenaemia. Metabolism 33: 714, 1984.","journal-title":"Metabolism"},{"key":"BF03350147_CR5","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/S0015-0282(16)48554-7","volume":"43","author":"T Loughlin","year":"1985","unstructured":"Loughlin T., Cunningham S.K., Culliton M., Smyth P.P.A., Meagher D.J., McKenna T.J. Altered androstenedione and estrone dynamics associated with abnormal hormonal profiles in amenorrhoeic subjects with weight loss or obesity. Fertil. Steril. 43: 720, 1985.","journal-title":"Fertil. Steril."},{"key":"BF03350147_CR6","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1210\/jcem-50-5-975","volume":"50","author":"JR Givens","year":"1980","unstructured":"Givens J.R., Wiedemann E., Andersen R.N., Kitabchi A.E. \u03b2-endorphin and \u03b2-lipotropin plasma levels in hirsute women: correlation with body weight. J. Clin. Endocrinol. Metab. 50: 975, 1980.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03350147_CR7","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/S0015-0282(16)48191-4","volume":"42","author":"FA Aleem","year":"1984","unstructured":"Aleem F.A., Mcintosh T. Elevated plasma levels of \u03b2-endorphin in a group of women with polycystic ovarian disease. Fertil. Steril. 42: 686, 1984.","journal-title":"Fertil. Steril."},{"key":"BF03350147_CR8","volume-title":"Proceedings of the 2nd Fogarty International Centre Conference on Obesity, No. 79","author":"GA Bray","year":"1979","unstructured":"Bray G.A. Obesity in America. Proceedings of the 2nd Fogarty International Centre Conference on Obesity, No. 79. Washington: U.S. DHEW, 1979."},{"key":"BF03350147_CR9","first-page":"277","volume":"36","author":"DT Krieger","year":"1980","unstructured":"Krieger D.T., Liotta A.S., Brownstein M.J., Zimmerman E.A. ACTH, \u03b2-lipotropin and related peptides in brain, pituitary and blood. Recent Prog. Horm. Res. 36: 277, 1980.","journal-title":"Recent Prog. Horm. Res."},{"key":"BF03350147_CR10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0009-8981(82)90165-6","volume":"123","author":"SK Cunningham","year":"1982","unstructured":"Cunningham S.K., McKenna T.J. A system for separation of cortisol, 11-deoxycortisol, 17-hydroxyprogesterone and progesterone in a single chromatographic step and its application to radioimmunoassay. Clin. Chim.Acta 123: 211, 1982.","journal-title":"Clin. Chim.Acta"},{"key":"BF03350147_CR11","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1080\/00032717208066108","volume":"5","author":"J Coyotupa","year":"1972","unstructured":"Coyotupa J., Farlow A.F., Abraham G.E. Simultaneous radioimmunoassay of plasma testosterone and dihydrotestosterone. Anal. Lett. 5: 329, 1972.","journal-title":"Anal. Lett."},{"key":"BF03350147_CR12","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/jcem-37-4-581","volume":"37","author":"GE Abraham","year":"1973","unstructured":"Abraham G.E., Chakmakjian Z.H. Serum steroid levels during the menstrual cycle in a bilaterally adrenalectomized woman. J. Clin. Endocrinol. Metab. 37: 581, 1973.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03350147_CR13","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1530\/acta.0.0750461","volume":"75","author":"MF Proeschel","year":"1974","unstructured":"Proeschel M.F., Courvalin J.C., Donnadieu M., Binoux M., Girard F. Preparation and evaluation of ACTH antibodies. Acta Endocrinol. (Kbh.) 75: 461, 1974.","journal-title":"Acta Endocrinol. (Kbh.)"},{"key":"BF03350147_CR14","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1210\/jcem-56-6-1338","volume":"56","author":"JM Kuhn","year":"1983","unstructured":"Kuhn J.M., Bertagna X., Seurin D., Gourmelen M., Girard F. Plasma lipotropin increase in man after growth hormone administration. Comparison between extractive and biosynthetic hormones. J. Clin. Endocrinol. Metab. 56: 1338, 1983.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03350147_CR15","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1172\/JCI110004","volume":"67","author":"XY Bertagna","year":"1981","unstructured":"Bertagna X.Y., Stones W.J., Nicholson W.E., Mount C.D., Orth D.N. Simultaneous assay of immunoreactive \u03b2-lipotropin, \u03b3-lipotropin and \u03b2-endorphin in plasma of normal human subjects, patients with ACTH\/lipotropin hypersecretory syndromes, and patients undergoing chronic hemodialysis. J. Clin. Invest. 67: 124, 1981.","journal-title":"J. Clin. Invest."},{"key":"BF03350147_CR16","first-page":"189","volume-title":"Statistical methods in medical research","author":"P Armitage","year":"1971","unstructured":"Armitage P. Statistical methods in medical research. Blackwell, Oxford, 1971, p. 189."},{"key":"BF03350147_CR17","first-page":"200","volume-title":"Lectures in biostatistics","author":"D Colquhoun","year":"1971","unstructured":"Colquhoun D. Lectures in biostatistics. Clarendon Press, Oxford, 1971, p. 200."},{"key":"BF03350147_CR18","first-page":"173","volume-title":"Statistics in small doses","author":"WY Castle","year":"1977","unstructured":"Castle W.Y. Statistics in small doses. Churchill Livingstone, London, 1977, p. 173"},{"key":"BF03350147_CR19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1677\/joe.0.0390061","volume":"39","author":"AP Sfikakis","year":"1967","unstructured":"Sfikakis A.P., Ikkos D.G., Diamandopoulos K.M. Urinary oestrogen excretion after metyrapone administration to patients with the polycystic ovary syndrome. J. Endocrinol. 39: 61, 1967.","journal-title":"J. Endocrinol."},{"key":"BF03350147_CR20","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1172\/JCI109261","volume":"62","author":"K Nakao","year":"1978","unstructured":"Nakao K., Nakai Y., Oki S., Hori K., Imura H. Presence of immunoreactive \u03b2-endorphin in normal human plasma. J. Clin. Invest. 62: 1395, 1978.","journal-title":"J. Clin. Invest."},{"key":"BF03350147_CR21","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1365-2265.1981.tb00658.x","volume":"15","author":"J Hope","year":"1981","unstructured":"Hope J., Ratter S.J., Estivariz F.E., McLoughlin L., Lowry P.J. Development of a radioimmunoassay for an amino-terminal peptide of pro-opiocortin containing the \u03b3-MSH region: measurement and characterization in human plasma. Clin. Endocrinol. (Oxf.) 15: 221, 1981.","journal-title":"Clin. Endocrinol. (Oxf.)"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03350147.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03350147\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03350147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T07:48:49Z","timestamp":1565336929000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03350147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,4]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1988,4]]}},"alternative-id":["BF03350147"],"URL":"https:\/\/doi.org\/10.1007\/bf03350147","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,4]]}}}