{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:54:04Z","timestamp":1771030444681,"version":"3.50.1"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1007\/dcr.0b013e3181d964c1","type":"journal-article","created":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T19:07:07Z","timestamp":1302203227000},"page":"1127-1134","source":"Crossref","is-referenced-by-count":18,"title":["The Prognostic Value of Hemoglobin in Patients With Anal Cancer Treated With Chemoradiotherapy"],"prefix":"10.1097","volume":"53","author":[{"given":"Gloria B.","family":"Rold\u00e1n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander K. P.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Buckner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony M.","family":"Magliocco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne M.","family":"Doll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-6-20210119","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s11894-008-0092-x","article-title":"Diagnosis and management of anal cancer.","volume":"10","author":"Gervaz","year":"2008","journal-title":"Curr Gastroenterol Rep"},{"key":"R2-6-20210119","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1634\/theoncologist.12-5-524","article-title":"Anal cancer: an overview.","volume":"12","author":"Uronis","year":"2007","journal-title":"Oncologist"},{"key":"R3-6-20210119","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/CCO.0b013e32816f76de","article-title":"Current treatment for localized anal carcinoma.","volume":"19","author":"Das","year":"2007","journal-title":"Curr Opin Oncol"},{"key":"R4-6-20210119","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF02604287","article-title":"Combined therapy for cancer of the anal canal.","volume":"24","author":"Nigro","year":"1981","journal-title":"Dis Colon Rectum"},{"key":"R5-6-20210119","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1200\/JCO.1997.15.5.2040","article-title":"Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups.","volume":"15","author":"Bartelink","year":"1997","journal-title":"J Clin Oncol"},{"key":"R6-6-20210119","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0140-6736(96)03409-5","article-title":"Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin.","volume":"348","author":"Northover","year":"1996","journal-title":"Lancet"},{"key":"R7-6-20210119","first-page":"31","article-title":"The impact of haemoglobin level on the response to radiotherapy.","volume":"7","author":"Haydaroglu","year":"2002","journal-title":"J BUON"},{"key":"R8-6-20210119","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1001\/archotol.134.11.1196","article-title":"Analysis of prognostic factors in patients with oropharyngeal squamous cell carcinoma treated with radiotherapy alone or in combination with systemic chemotherapy.","volume":"134","author":"Pedruzzi","year":"2008","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R9-6-20210119","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1093\/annonc\/mdm088","article-title":"Long-term outcomes with concurrent carboplatin, paclitaxel and radiation therapy for locally advanced, inoperable head and neck cancer.","volume":"18","author":"Agarwala","year":"2007","journal-title":"Ann Oncol"},{"key":"R10-6-20210119","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.ijrobp.2007.04.047","article-title":"Clinical parameters predicting pathologic tumor response after preoperative chemoradiotherapy for rectal cancer.","volume":"69","author":"Yoon","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R11-6-20210119","first-page":"258","article-title":"Stage IIIA and IIIB non-small cell lung cancer: results of chemotherapy combined with radiation therapy and analysis of prognostic factors.","volume":"43","author":"Sanchez de Cos Escuin","year":"2007","journal-title":"Arch Bonconeumol"},{"key":"R12-6-20210119","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.clon.2006.09.001","article-title":"Anaemia is associated with poor overall survival but not with inferior local control in patients with muscle invasive bladder carcinoma treated by radical external beam radiotherapy: a retrospective study.","volume":"18","author":"Joynson","year":"2006","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"R13-6-20210119","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.clon.2006.04.006","article-title":"Pre-treatment haemoglobin levels and the prediction of response to neoadjuvant chemotherapy in breast cancer.","volume":"18","author":"Beresford","year":"2006","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"R14-6-20210119","first-page":"302","article-title":"Definitive evidence for hypoxic cells influencing cure in cancer therapy.","volume":"3","author":"Bush","year":"1978","journal-title":"Br J Cancer Suppl"},{"key":"R15-6-20210119","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0167-8140(00)00245-0","article-title":"Anemia, hypoxia and transfusion in patients with cervix cancer: a review.","volume":"57","author":"Fyles","year":"2000","journal-title":"Radiother Oncol"},{"key":"R16-6-20210119","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1002\/(SICI)1097-0142(19991015)86:8<1528::AID-CNCR20>3.0.CO;2-E","article-title":"The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix.","volume":"86","author":"Grogan","year":"1999","journal-title":"Cancer"},{"key":"R17-6-20210119","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0360-3016(97)00329-5","article-title":"Time-dose considerations in the treatment of anal cancer.","volume":"39","author":"Constantinou","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R18-6-20210119","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1001\/jama.299.16.1914","article-title":"Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.","volume":"299","author":"Ajani","year":"2008","journal-title":"JAMA"},{"key":"R19-6-20210119","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.ijrobp.2007.08.074","article-title":"Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy.","volume":"70","author":"Mell","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R20-6-20210119","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1442-2050.2007.00750.x","article-title":"Impact of hemoglobin level on survival in definitive chemoradiotherapy for T4\/M1 lymph node esophageal cancer.","volume":"21","author":"Zenda","year":"2008","journal-title":"Dis Esophagus"},{"key":"R21-6-20210119","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.ygyno.2006.03.039","article-title":"Anemia in patients with locally advanced cervical carcinoma administered preoperative radiochemotherapy: association with pathological response to treatment and clinical outcome.","volume":"103","author":"Ferrandina","year":"2006","journal-title":"Gynecol Oncol"},{"key":"R22-6-20210119","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1182\/blood-2005-07-3046","article-title":"The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?","volume":"107","author":"Beutler","year":"2006","journal-title":"Blood"},{"key":"R23-6-20210119","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1525-1438.2007.01032.x","article-title":"Effects of anemia correction with epoetin beta in patients receiving radiochemotherapy for advanced cervical cancer.","volume":"18","author":"Strauss","year":"2008","journal-title":"Int J Gynecol Cancer"},{"key":"R24-6-20210119","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00066-006-1543-7","article-title":"Impact of hemoglobin levels on tumor oxygenation: the higher, the better?","volume":"182","author":"Vaupel","year":"2006","journal-title":"Strahlenther Onkol"},{"key":"R25-6-20210119","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1080\/02841860600833160","article-title":"Clinical relevance of hemoglobin level in cervical cancer patients administered definitive radiotherapy.","volume":"45","author":"Serkies","year":"2006","journal-title":"Acta Oncol"},{"key":"R26-6-20210119","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1046\/j.1563-258X.2002.02032.x","article-title":"Hypoxia in breast cancer: pathogenesis characterization and biological\/therapeutic implications.","volume":"152","author":"Vaupel","year":"2002","journal-title":"Wien Med Wochenschr"},{"key":"R27-6-20210119","first-page":"7634","article-title":"Oxygenation gain factor: a novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers.","volume":"63","author":"Vaupel","year":"2003","journal-title":"Cancer Res"},{"key":"R28-6-20210119","first-page":"117","article-title":"Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology.","author":"Dunst","year":"2002"},{"key":"R29-6-20210119","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s00066-002-1081-x","article-title":"Oxygenation status of gynecologic tumors: what is the optimal hemoglobin level?","volume":"178","author":"Vaupel","year":"2002","journal-title":"Strahlenther Onkol"},{"key":"R30-6-20210119","first-page":"31","article-title":"Intratumoral oxygenation of invasive squamous cell carcinoma of the vulva is not correlated with regional lymph node metastasis.","volume":"26","author":"Stone","year":"2005","journal-title":"Eur J Gynaecol Oncol"},{"key":"R31-6-20210119","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/PL00002427","article-title":"Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer.","volume":"177","author":"Rudat","year":"2001","journal-title":"Strahlenther Onkol"},{"key":"R32-6-20210119","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0167-8140(99)00139-5","article-title":"Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix.","volume":"53","author":"Knocke","year":"1999","journal-title":"Radiother Oncol"},{"key":"R33-6-20210119","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0167-8140(98)00044-9","article-title":"Oxygenation predicts radiation response and survival in patients with cervix cancer.","volume":"48","author":"Fyles","year":"1998","journal-title":"Radiother Oncol"},{"key":"R34-6-20210119","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1080\/02841860410026189","article-title":"Tumor hypoxia is independent of hemoglobin and prognostic for loco-regional tumor control after primary radiotherapy in advanced head an neck cancer.","volume":"43","author":"Nordsmark","year":"2004","journal-title":"Acta Oncol"},{"key":"R35-6-20210119","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/(SICI)1097-0347(199903)21:2<146::AID-HED8>3.0.CO;2-U","article-title":"Tissue oxygen distribution in head and neck cancer patients.","volume":"21","author":"Adam","year":"1999","journal-title":"Head Neck"},{"key":"R36-6-20210119","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ygyno.2006.12.037","article-title":"Anemia correction in malignancy management: treta or opportunity?","volume":"105","author":"De Los Santos","year":"2007","journal-title":"Gynecol Oncol"}],"container-title":["Diseases of the Colon &amp; Rectum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1007\/DCR.0b013e3181d964c1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T16:27:57Z","timestamp":1620923277000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003453-201008000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1007\/dcr.0b013e3181d964c1","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}