{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:54:21Z","timestamp":1789088061481,"version":"build-2803163510"},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1999,5,1]],"date-time":"1999-05-01T00:00:00Z","timestamp":925516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1999,5]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p>A series of 151 women underwent 156 preoperative localizations of nonpalpable, mammographically detected breast lesions. Indications for biopsy were (1) a cluster of more than five fine microcalcifications; (2) a solid lump found by ultrasound investigation; and (3) a radiologic abnormality of the breast parenchyma. The lesions were localized preoperatively using the hook\u2010wire method (Frank needle), and all biopsies were performed under general anesthesia. Carcinoma was discovered in 34 (21.8%) cases; in 22 (64.7%) it was a noninvasive cancer (9 with microinvasions) and in 12 (35.3%) an invasive carcinoma with a mean tumor diameter of 0.8\u00a0cm. The highest malignancy rate was found among those with microcalcifications (21 of 81 cancers, or 25.9%). Lymph node involvement was seen in 25% of patients with invasive carcinomas. In conclusion, the needle localization of nonpalpable breast lesions is a simple, accurate method for early detection of small cancers with favorable prognosis.<\/jats:p>","DOI":"10.1007\/pl00012323","type":"journal-article","created":{"date-parts":[[2006,2,17]],"date-time":"2006-02-17T17:07:36Z","timestamp":1140196056000},"page":"434-438","source":"Crossref","is-referenced-by-count":12,"title":["Management of Nonpalpable, Mammographically Detectable Breast Lesions"],"prefix":"10.1002","volume":"23","author":[{"given":"Christos","family":"Markopoulos","sequence":"first","affiliation":[{"name":"Breast Unit 2nd Department of Propedeutic Surgery Athens University Medical School Laiko General Hospital 17 Ag. Thoma Avenue 11527 Athens Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kakisis","sequence":"additional","affiliation":[{"name":"Breast Unit 2nd Department of Propedeutic Surgery Athens University Medical School Laiko General Hospital 17 Ag. Thoma Avenue 11527 Athens Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stratos","family":"Kouskos","sequence":"additional","affiliation":[{"name":"Breast Unit 2nd Department of Propedeutic Surgery Athens University Medical School Laiko General Hospital 17 Ag. Thoma Avenue 11527 Athens Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Kontzoglou","sequence":"additional","affiliation":[{"name":"Breast Unit 2nd Department of Propedeutic Surgery Athens University Medical School Laiko General Hospital 17 Ag. Thoma Avenue 11527 Athens Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Koufopoulos","sequence":"additional","affiliation":[{"name":"Breast Unit 2nd Department of Propedeutic Surgery Athens University Medical School Laiko General Hospital 17 Ag. Thoma Avenue 11527 Athens Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Gogas","sequence":"additional","affiliation":[{"name":"Breast Unit 2nd Department of Propedeutic Surgery Athens University Medical School Laiko General Hospital 17 Ag. Thoma Avenue 11527 Athens Greece<!--<country1>GR<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1999,5]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/PL00012323.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/PL00012323\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/PL00012323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T08:20:17Z","timestamp":1704874817000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/PL00012323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,5]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,5]]}},"alternative-id":["10.1007\/PL00012323"],"URL":"https:\/\/doi.org\/10.1007\/pl00012323","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,5]]}}}