{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:44:54Z","timestamp":1783485894867,"version":"3.55.0"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1998,6,1]],"date-time":"1998-06-01T00:00:00Z","timestamp":896659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[1998,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Amiodarone\u2010associated thyrotoxicosis, often clinically mild and resolutive after amiodarone discontinuation or under medical therapy, is sometimes drug unresponsive and not uncommonly follows a dramatic, even fatal course. Therefore, we considered a surgical solution in 15 severely amiodarone\u2010associated thyrotoxic patients. Twelve men and three women (mean age 68 years, range 50\u201384 years) underwent radical thyroidectomy for clinical and biologically proved amiodarone\u2010associated thyrotoxicosis. In six surgery was the first\u2010line therapeutic option. In the other nine thyroidectomy seemed unavoidable considering the unresponsiveness to medical therapy and rapid deterioration of the patients\u2019 clinical condition, with life\u2010threatening cardiac failure in three. In every patient surgery was conducted without immediate or delayed complications. Total thyroidectomy proved uniformly, definitively, and rapidly effective in controlling thyrotoxicosis in all patients, with a spectacular reversal of cardiac failure in the three most critical cases. Surgery was beneficial to our 15 patients and undoubtedly life\u2010saving in the three most worrying cases. These results suggest that thyroidectomy should be more liberally regarded as an interesting alternative to conventional, but unpredictably effective, medical therapies.<\/jats:p>","DOI":"10.1007\/pl00024613","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T15:19:10Z","timestamp":1658243950000},"page":"537-543","source":"Crossref","is-referenced-by-count":41,"title":["Surgical Management of Amiodarone\u2010associated Thyrotoxicosis: Too Risky or Too Effective?"],"prefix":"10.1002","volume":"22","author":[{"given":"Etienne","family":"Hamoir","sequence":"first","affiliation":[{"name":"Department of Surgery Division of Endocrine Surgery University of Liege Domaine Universitaire du Sart\u2010Tilman, B35 4000 Liege Belgium<!--<country1>BE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Meurisse","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Endocrine Surgery University of Liege Domaine Universitaire du Sart\u2010Tilman, B35 4000 Liege Belgium<!--<country1>BE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Defechereux","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Endocrine Surgery University of Liege Domaine Universitaire du Sart\u2010Tilman, B35 4000 Liege Belgium<!--<country1>BE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Joris","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Liege Domaine Universitaire du Sart\u2010Tilman B35 4000 Liege Belgium<!--<country1>BE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Vivario","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Liege Domaine Universitaire du Sart\u2010Tilman B35 4000 Liege Belgium<!--<country1>BE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Hennen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology University of Liege Domaine Universitaire du Sart\u2010Tilman B35 4000 Liege Belgium<!--<country1>BE<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1998,6]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/PL00024613.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/PL00024613\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/PL00024613.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/PL00024613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:51:18Z","timestamp":1704991878000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/PL00024613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["10.1007\/PL00024613"],"URL":"https:\/\/doi.org\/10.1007\/pl00024613","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}