{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T12:45:06Z","timestamp":1766407506798},"reference-count":140,"publisher":"Walter de Gruyter GmbH","issue":"5","license":[{"start":{"date-parts":[[2009,8,18]],"date-time":"2009-08-18T00:00:00Z","timestamp":1250553600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch. Immunol. Ther. Exp."],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1007\/s00005-009-0042-9","type":"journal-article","created":{"date-parts":[[2009,8,17]],"date-time":"2009-08-17T16:13:33Z","timestamp":1250525613000},"page":"355-367","source":"Crossref","is-referenced-by-count":39,"title":["Factors that deregulate the protective immune response in tuberculosis"],"prefix":"10.2478","volume":"57","author":[{"given":"Rogelio","family":"Hernandez-Pando","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hector","family":"Orozco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2009,8,18]]},"reference":[{"key":"42_CR1","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1084\/jem.20052302","volume":"202","author":"A Alcais","year":"2005","unstructured":"Alcais A, Fieschi C, Abel L et\u00a0al (2005) Tuberculosis in children and adults: two distinct genetic diseases. J Exp Med 202: 1617\u20131621","journal-title":"J Exp Med"},{"key":"42_CR2","first-page":"1","volume":"142","author":"JA Armstrong","year":"1975","unstructured":"Armstrong JA, Hart PD (1975) Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacillus. Reversal of the usual nonfusion pattern and observations on bacterial survival. J Exp Med 142: 1\u201316","journal-title":"Reversal of the usual nonfusion pattern and observations on bacterial survival. J Exp Med"},{"key":"42_CR3","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1378\/chest.119.4.1131","volume":"119","author":"J Ashitani","year":"2001","unstructured":"Ashitani J, Mukae H, Hiratsuka T et\u00a0al (2001) Plasma and BAL fluid concentrations of antimicrobial peptides in patients with Mycobacterium avium-intracellulare infection. Chest 119: 1131\u20131137","journal-title":"Chest"},{"key":"42_CR4","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1002\/1529-0131(199906)42:6<1168::AID-ANR13>3.0.CO;2-L","volume":"42","author":"SP Atamas","year":"1999","unstructured":"Atamas SP, Yurovsky VV, Wise R et\u00a0al (1999) Production of Type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis. Arthritis Rheum 42: 1168\u20131179","journal-title":"Arthritis Rheum"},{"key":"42_CR5","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1365-3083.2005.01623.x","volume":"61","author":"H Aung","year":"2005","unstructured":"Aung H, Wu M, Johnson JL et\u00a0al (2005) Bioactivation of latent transforming growth factor beta1 by Mycobacterium tuberculosis in human mononuclear phagocytes. Scand J Immunol 61: 558\u2013565","journal-title":"Scand J Immunol"},{"key":"42_CR6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/rr25","volume":"1","author":"R Bals","year":"2000","unstructured":"Bals R (2000) Epithelial antimicrobial peptides in host defense against infection. Respir Res 1: 141\u2013150","journal-title":"Respir Res"},{"key":"42_CR7","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1172\/JCI2410","volume":"102","author":"R Bals","year":"1998","unstructured":"Bals R, Wang X, Wu Z et\u00a0al (1998) Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest 102: 874\u2013880","journal-title":"J Clin Invest"},{"key":"42_CR8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/32588","volume":"392","author":"J Banchereau","year":"1998","unstructured":"Banchereau J, Steinman R (1998) Dendritic cells and the control of immunity. Nature 392: 245\u2013252","journal-title":"Nature"},{"key":"42_CR9","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1084\/jem.20011629","volume":"195","author":"FJ Barrat","year":"2002","unstructured":"Barrat FJ, Cua DJ, Boonstra A et\u00a0al (2002) In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1) and Th2-inducing cytokines. J Exp Med 195: 603\u2013616","journal-title":"J Exp Med"},{"key":"42_CR10","first-page":"147","volume":"7","author":"H Baumann","year":"1990","unstructured":"Baumann H, Gauldie J (1990) Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation. Mol Biol Med 7: 147\u2013159","journal-title":"Mol Biol Med"},{"key":"42_CR11","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/0167-5699(94)90137-6","volume":"15","author":"H Baumann","year":"1994","unstructured":"Baumann H, Gauldie J (1994) The acute phase response. Immunol Today 15: 74\u201380","journal-title":"Immunol Today"},{"key":"42_CR12","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1084\/jem.189.12.1973","volume":"189","author":"SM Behar","year":"1999","unstructured":"Behar SM, Dascher CC, Grusby MJ (1999) Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. J Exp Med 189: 1973\u20131980","journal-title":"J Exp Med"},{"key":"42_CR13","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1128\/IAI.64.4.1400-1406.1996","volume":"64","author":"LE Bermudez","year":"1996","unstructured":"Bermudez LE, Goodman J (1996) Mycobacterium tuberculosis invades and replicates within type II alveolar cells. Infect Immun 64: 1400\u20131406","journal-title":"Infect Immun"},{"key":"42_CR14","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1084\/jem.167.5.1708","volume":"167","author":"R Bertini","year":"1988","unstructured":"Bertini R, Bianchi M, Ghezzi P (1988) Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor. J Exp Med 167: 1708\u20131712","journal-title":"J Exp Med"},{"key":"42_CR15","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1038\/ni725","volume":"2","author":"T Biedermann","year":"2001","unstructured":"Biedermann T, Zimmermann S, Himmelrich H et\u00a0al (2001) IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB\/c mice. Nat Immunol 2: 1054\u20131060","journal-title":"Nat Immunol"},{"key":"42_CR16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/bmb\/61.1.1","volume":"61","author":"RJ Boyton","year":"2002","unstructured":"Boyton RJ, Openshaw PJ (2002) Pulmonary defences to acute respiratory infection. Br Med Bull 61: 1\u201312","journal-title":"Br Med Bull"},{"key":"42_CR17","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1126\/science.1636090","volume":"257","author":"P Bretscher","year":"1992","unstructured":"Bretscher P, Wei G, Menon JN et\u00a0al (1992) Establishment of stable cell-mediated immunity that makes \u201csusceptible\u201d mice resistant to Leishmania major. Science 257: 539\u2013542","journal-title":"Science"},{"key":"42_CR18","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1128\/IAI.63.8.2983-2988.1995","volume":"63","author":"DH Brown","year":"1995","unstructured":"Brown DH, LaFuse W, Zwilling BS (1995) Cytokine-mediated activation of macrophages from Mycobacterium bovis BCG-resistant and -susceptible mice, differential effects of corticosterone on antimicobacterial activity and expression of the Bcg gene. Infect Immun 63: 2983\u20132988","journal-title":"Infect Immun"},{"key":"42_CR19","doi-asserted-by":"crossref","first-page":"5407","DOI":"10.4049\/jimmunol.162.9.5407","volume":"162","author":"AM Caruso","year":"1999","unstructured":"Caruso AM, Serbina N, Klein E et\u00a0al (1999) Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis. J Immunol 162: 5407\u20135416","journal-title":"J Immunol"},{"key":"42_CR20","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1128\/IAI.59.5.1755-1761.1991","volume":"59","author":"J Chan","year":"1991","unstructured":"Chan J, Fan XD, Hunter SW et\u00a0al (1991) Lipoarabinomannan, a possible virulence factor involved in persistence of Mycobacterium tuberculosis within macrophages. Infect Immun 59: 1755\u20131761","journal-title":"Infect Immun"},{"key":"42_CR21","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1084\/jem.175.4.1111","volume":"175","author":"J Chan","year":"1992","unstructured":"Chan J, Xing Y, Magliozzo RS et\u00a0al (1992) Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated macrophages. J Exp Med 175: 1111\u20131122","journal-title":"J Exp Med"},{"key":"42_CR22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0966-842X(96)81528-9","volume":"4","author":"DL Clemens","year":"1996","unstructured":"Clemens DL (1996) Characterization of the Mycobacterium tuberculosis phagosome. Trends Microbiol 4: 113\u2013118","journal-title":"Trends Microbiol"},{"key":"42_CR23","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1128\/IAI.59.5.1823-1831.1991","volume":"59","author":"AJ Crowle","year":"1991","unstructured":"Crowle AJ, Dahl R, Ross E et\u00a0al (1991) Evidence that vescicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect Immun 59: 1823\u20131931","journal-title":"Infect Immun"},{"key":"42_CR24","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1128\/JVI.60.3.1068-1074.1986","volume":"60","author":"KA Daher","year":"1986","unstructured":"Daher KA, Selsted ME, Lehrer RI (1986) Direct inactivation of viruses by human granulocyte defensins. J Virol 60: 1068\u20131074","journal-title":"J Virol"},{"key":"42_CR25","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1128\/IAI.64.2.399-405.1996","volume":"64","author":"KE Dahl","year":"1996","unstructured":"Dahl KE, Shiratsuchi H, Hamilton BD et\u00a0al (1996) Selective induction of transforming growth factor beta in human monocytes by lipoarabinomannan of Mycobacterium tuberculosis. Infect Immun 64: 399\u2013405","journal-title":"Infect Immun"},{"key":"42_CR26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1054\/tuld.1998.0198","volume":"79","author":"G Dai","year":"1999","unstructured":"Dai G, McMurray DN (1999) Effects of modulating TGF-beta 1 on immune responses to mycobacterial infection in guinea pigs. Tuber Lung Dis 79: 207\u2013214","journal-title":"Tuber Lung Dis"},{"key":"42_CR27","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0923-2494(91)90010-G","volume":"142","author":"RA Daynes","year":"1991","unstructured":"Daynes RA, Meikle AW, Araneo BA (1991) Locally active steroids hormones may facilitate compartamentalization of immunity by regulating the type of lymphokines produced by helper T cells. Res Immunol 142: 40\u201345","journal-title":"Res Immunol"},{"key":"42_CR28","doi-asserted-by":"crossref","first-page":"6711","DOI":"10.1128\/IAI.73.10.6711-6720.2005","volume":"73","author":"S Valliere de","year":"2005","unstructured":"de Valliere S, Abate G, Blazevic A et\u00a0al (2005) Enhancement of innate and cell-mediated immunity by antimycobacterial antibodies. Infect Immun 73: 6711\u20136720","journal-title":"Infect Immun"},{"key":"42_CR29","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1006\/clin.1998.4587","volume":"88","author":"G Diamond","year":"1998","unstructured":"Diamond G, Bevins CL (1998) beta-Defensins: endogenous antibiotics of the innate host defense response. Clin Immunol Immunopathol 88: 221\u2013225","journal-title":"Clin Immunol Immunopathol"},{"key":"42_CR30","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1002\/eji.1830270941","volume":"27","author":"AJ Engering","year":"1997","unstructured":"Engering AJ, Cella M, Fluitsma D et\u00a0al (1997) The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells. Eur J Immunol 27: 2417\u20132425","journal-title":"Eur J Immunol"},{"key":"42_CR31","doi-asserted-by":"crossref","first-page":"541","DOI":"10.4049\/jimmunol.157.2.541","volume":"157","author":"NA Fanger","year":"1996","unstructured":"Fanger NA, Wardwell K, Shen L et\u00a0al (1996) Type I (CD64) and type II (CD32) Fc gamma receptor-mediated phagocytosis by human blood dendritic cells. J Immunol 157: 541\u2013548","journal-title":"J Immunol"},{"key":"42_CR32","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1128\/IAI.68.5.2827-2836.2000","volume":"68","author":"G Fenhalls","year":"2000","unstructured":"Fenhalls G, Wong A, Bezuidenhout J et\u00a0al (2000) In situ production of gamma interferon, interleukin-4, and tumor necrosis factor alpha mRNA in human lung tuberculosis granulomas. Infect Immun 68: 2827\u20132836","journal-title":"Infect Immun"},{"key":"42_CR33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0092-8674(00)80754-0","volume":"97","author":"G Ferrari","year":"1999","unstructured":"Ferrari G, Langen H, Naito M et\u00a0al (1999) A coat protein on phagosomes involved in the intracelular survival of mycobacteria. Cell 97: 435\u2013447","journal-title":"Cell"},{"key":"42_CR34","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.imlet.2004.09.008","volume":"98","author":"G Fiorenza","year":"2005","unstructured":"Fiorenza G, Rateni L, Farroni MA et\u00a0al (2005) TNF-alpha, TGF-beta and NO relationship in sera from tuberculosis (TB) patients of different severity. Immunol Lett 98: 45\u201348","journal-title":"Immunol Lett"},{"key":"42_CR35","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.4049\/jimmunol.168.6.2689","volume":"168","author":"K Fischer","year":"2002","unstructured":"Fischer K, Collins H, Taniguchi M et\u00a0al (2002) IL-4 and T cells are required for the generation of IgG1 isotype antibodies against cardiolipin. J Immunol 168: 2689\u20132694","journal-title":"J Immunol"},{"key":"42_CR36","doi-asserted-by":"crossref","first-page":"12013","DOI":"10.1073\/pnas.89.24.12013","volume":"89","author":"JL Flynn","year":"1992","unstructured":"Flynn JL, Goldstein MM, Triebold KJ et\u00a0al (1992) Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 89: 12013\u201312017","journal-title":"Proc Natl Acad Sci USA"},{"key":"42_CR37","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.4049\/jimmunol.160.4.1796","volume":"160","author":"JL Flynn","year":"1998","unstructured":"Flynn JL, Scanga CA, Tanaka KE et\u00a0al (1998) Effects of aminoguanidine on latent murine tuberculosis. J Immunol 160: 1796\u20131803","journal-title":"J Immunol"},{"key":"42_CR38","doi-asserted-by":"crossref","first-page":"5610","DOI":"10.1073\/pnas.86.14.5610","volume":"86","author":"JE Gabay","year":"1989","unstructured":"Gabay JE, Scott RW, Campanelli D et\u00a0al (1989) Antibiotic proteins of human polymorphonuclear leukocytes. Proc Natl Acad Sci USA 86: 5610\u20135614","journal-title":"Proc Natl Acad Sci USA"},{"key":"42_CR39","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/nri1180","volume":"3","author":"T Ganz","year":"2003","unstructured":"Ganz T (2003) Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol 3: 710\u2013720","journal-title":"Nat Rev Immunol"},{"key":"42_CR40","first-page":"1427","volume":"76","author":"T Ganz","year":"1985","unstructured":"Ganz T, Selsted ME, Szklarek D et\u00a0al (1985) Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest 76: 1427\u20131435","journal-title":"Natural peptide antibiotics of human neutrophils. J Clin Invest"},{"key":"42_CR41","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1046\/j.1365-2567.2004.01904.x","volume":"112","author":"GS Garc\u00eda-Romo","year":"2004","unstructured":"Garc\u00eda-Romo GS, Pedroza-Gonzalez A, Aguilar-Leon D et\u00a0al (2004) Airways infection with virulent Mycobacterium tuberculosis delays the influx of dendritic cells and the expression of costimulatory molecules in mediastinal lymph nodes. Immunology 112: 661\u2013668","journal-title":"Immunology"},{"key":"42_CR42","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1126\/science.288.5471.1647","volume":"288","author":"J Gatfield","year":"2000","unstructured":"Gatfield J, Pieters J (2000) Essential role of cholesterol in entry of mycobacteria into macrophages. Science 288: 1647\u20131650","journal-title":"Science"},{"key":"42_CR43","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1084\/jem.20021229","volume":"197","author":"TB Geijtenbeek","year":"2003","unstructured":"Geijtenbeek TB, Van Vliet SJ, Koppel EA et\u00a0al (2003) Mycobacteria target DC-SIGN to suppress dendritic cell function. J Exp Med 197: 7\u201317","journal-title":"J Exp Med"},{"key":"42_CR44","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0952-7915(00)00243-0","volume":"13","author":"JE Gumperz","year":"2001","unstructured":"Gumperz JE, Brenner MB (2001) CD1-specific T cells in microbial immunity. Curr Opin Immunol 13: 471\u2013478","journal-title":"Curr Opin Immunol"},{"key":"42_CR45","first-page":"545","volume":"24","author":"Z Hasan","year":"1997","unstructured":"Hasan Z, Schlax C, Kuhn L et\u00a0al (1997) Isolation and characterization of the mycobacterial phagosome: segregation from the endosomal\/lysosomal pathway. Mol Microbiol 24: 545\u2013553","journal-title":"Mol Microbiol"},{"key":"42_CR46","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/eji.200324253","volume":"34","author":"R Hernandez-Pando","year":"2004","unstructured":"Hernandez-Pando R, Aguilar D, Hernandez ML et\u00a0al (2004) Pulmonary tuberculosis in BALB\/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. Eur J Immunol 34: 174\u2013183","journal-title":"Eur J Immunol"},{"key":"42_CR47","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1086\/426453","volume":"191","author":"R Hernandez-Pando","year":"2005","unstructured":"Hernandez-Pando R, Aguilar-Leon D, Orozco H et\u00a0al (2005) 16 alpha-Bromoepiandrosterone restores T helper cell Type 1 activity and accelerates chemotherapy-induced bacterial clearance in a model of progressive pulmonary tuberculosis. J Infect Dis 191: 299\u2013306","journal-title":"J Infect Dis"},{"key":"42_CR48","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1006\/exmp.1998.2224","volume":"65","author":"R Hernandez-Pando","year":"1998","unstructured":"Hernandez-Pando R, Arriaga AK, Panduro CA et\u00a0al (1998a) The response of hepatic acute phase proteins during experimental pulmonary tuberculosis. Exp Mol Pathol 65: 25\u201336","journal-title":"Exp Mol Pathol"},{"key":"42_CR49","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/S0140-6736(00)03493-0","volume":"356","author":"R Hernandez-Pando","year":"2000","unstructured":"Hernandez-Pando R, Jeyanathan M, Mengistu G et\u00a0al (2000) Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 356: 2133\u20132138","journal-title":"Lancet"},{"key":"42_CR50","first-page":"26","volume":"89","author":"R Hernandez-Pando","year":"1996","unstructured":"Hernandez-Pando R, Orozco EH, Sampieri A et\u00a0al (1996) Correlation between the kinetics of Th1, Th2 cells and pathology in a murine model of experimental pulmonary pathology. Immunology 89: 26\u201333","journal-title":"Immunology"},{"key":"42_CR51","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1046\/j.1365-2567.1997.00193.x","volume":"90","author":"R Hernandez-Pando","year":"1997","unstructured":"Hernandez-Pando R, Orozco H, Arriaga K et\u00a0al (1997a) Analysis of the local kinetics and localization of interleukin-1 alpha, tumor necrosis factor-alpha and transforming growth factor-beta, during the course of experimental pulmonary tuberculosis. Immunology 90: 607\u2013617","journal-title":"Immunology"},{"key":"42_CR52","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1574-695X.1995.tb00176.x","volume":"12","author":"R Hernandez-Pando","year":"1995","unstructured":"Hernandez-Pando R, Orozco H, Honour J et\u00a0al (1995) Adrenal changes in murine pulmonary tuberculosis a clue to pathogenesis. FEMS Immunol Med Microbiol 12: 63\u201372","journal-title":"FEMS Immunol Med Microbiol"},{"key":"42_CR53","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1365-2249.2006.03049.x","volume":"144","author":"R Hernandez-Pando","year":"2006","unstructured":"Hernandez-Pando R, Orozco-Esteves H, Maldonado HA et\u00a0al (2006) A combination of a transforming growth factor-beta antagonist and an inhibitor of cyclooxygenase is an effective treatment for murine pulmonary tuberculosis. Clin Exp Immunol 144: 264\u2013272","journal-title":"Clin Exp Immunol"},{"key":"42_CR54","doi-asserted-by":"crossref","first-page":"3317","DOI":"10.1128\/IAI.65.8.3317-3327.1997","volume":"65","author":"R Hernandez-Pando","year":"1997","unstructured":"Hernandez-Pando R, Pavon L, Arriaga K et\u00a0al (1997b) Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental mycobacteria saprophyte before infection. Infect Immun 65: 3317\u20133327","journal-title":"Infect Immun"},{"key":"42_CR55","first-page":"591","volume":"82","author":"R Hernandez-Pando","year":"1994","unstructured":"Hernandez-Pando R, Rook GA (1994) The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1\/Th2 cytokine balance. Immunology 82: 591\u2013595","journal-title":"Immunology"},{"key":"42_CR56","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1078\/0940-2993-00182","volume":"53","author":"R Hernandez-Pando","year":"2001","unstructured":"Hernandez-Pando R, Sch\u00f6n T, Orozco EH et\u00a0al (2001) Expression of inducible nitric oxide synthase and nitrotyrosine during the evolution of experimental pulmonary tuberculosis. Exp Toxicol Pathol 53: 257\u2013265","journal-title":"Exp Toxicol Pathol"},{"key":"42_CR57","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1046\/j.1365-2567.1998.00601.x","volume":"95","author":"Hernandez-Pando","year":"1998","unstructured":"Hernandez-Pando, Streber ML, Orozco H et\u00a0al (1998b) The effects of androstenediol and dehydroepiandosterone on the course and cytokine profile of tuberculosis in BALB\/c mice. Immunology 95: 234\u2013241","journal-title":"Immunology"},{"key":"42_CR58","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S0022-2143(99)90204-4","volume":"134","author":"DF Hoft","year":"1999","unstructured":"Hoft DF, Kemp EB, Marinaro M et\u00a0al (1999) A double-blind, placebo-controlled study of Mycobacterium-specific human immune responses induced by intradermal bacille Calmette-Guerin vaccination. J Lab Clin Med 134: 244\u2013252","journal-title":"J Lab Clin Med"},{"key":"42_CR59","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1086\/344359","volume":"186","author":"DF Hoft","year":"2002","unstructured":"Hoft DF, Worku S, Kampmann B et\u00a0al (2002) Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective Mycobacterium tuberculosis immunity. J Infect Dis 186: 1448\u20131457","journal-title":"J Infect Dis"},{"key":"42_CR60","doi-asserted-by":"crossref","first-page":"32911","DOI":"10.1074\/jbc.M006098200","volume":"275","author":"DM Hoover","year":"2000","unstructured":"Hoover DM, Rajashankar KR, Blumenthal R et\u00a0al (2000) The structure of human beta-defensin-2 shows evidence of higher order oligomerization. J Biol Chem 275: 32911\u201332918","journal-title":"J Biol Chem"},{"key":"42_CR61","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1002\/1521-4141(200111)31:11<3388::AID-IMMU3388>3.0.CO;2-Q","volume":"31","author":"D Jarrossay","year":"2001","unstructured":"Jarrossay D, Napolitani G, Colonna M et\u00a0al (2001) Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol 31: 3388\u20133393","journal-title":"Eur J Immunol"},{"key":"42_CR62","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/375151a0","volume":"375","author":"W Jiang","year":"1995","unstructured":"Jiang W, Swiggard WJ, Heufler C et\u00a0al (1995) The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375: 151\u2013155","journal-title":"Nature"},{"key":"42_CR63","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0952-7915(99)80055-7","volume":"11","author":"E Jouanguy","year":"1999","unstructured":"Jouanguy E, Doffinger R, Dupuis S et\u00a0al (1999) IL-12 and IFN-gamma in host defense against mycobacteria and salmonella in mice and men. Curr Opin Immunol 11: 346\u2013351","journal-title":"Curr Opin Immunol"},{"key":"42_CR64","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1084\/jem.194.6.863","volume":"194","author":"N Kadowaki","year":"2001","unstructured":"Kadowaki N, Ho S, Antonenko S et\u00a0al (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 194: 863\u2013869","journal-title":"J Exp Med"},{"key":"42_CR65","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1189\/jlb.68.6.779","volume":"68","author":"V Kaiser","year":"2000","unstructured":"Kaiser V, Diamond G (2000) Expression of mammalian defensin genes. J Leukoc Biol 68: 779\u2013784","journal-title":"J Leukoc Biol"},{"key":"42_CR66","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/S0171-2985(11)80463-8","volume":"191","author":"G Kaplan","year":"1994","unstructured":"Kaplan G (1994) Cytokine regulation of disease progression in leprosy and tuberculosis. Immunobiology 191: 564\u2013568","journal-title":"Immunobiology"},{"key":"42_CR67","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1128\/IAI.69.4.2692-2699.2001","volume":"69","author":"KO Kisich","year":"2001","unstructured":"Kisich KO, Heifets L, Higgins M et\u00a0al (2001) Antimycobacterial agent based on mRNA encoding human beta-defensin 2 enables primary macrophages to restrict growth of Mycobacterium tuberculosis. Infect Immun 69: 2692\u20132699","journal-title":"Infect Immun"},{"key":"42_CR68","doi-asserted-by":"crossref","first-page":"5250","DOI":"10.1038\/sj.emboj.7601407","volume":"25","author":"GB Kyei","year":"2006","unstructured":"Kyei GB, Vergne I, Chua J et\u00a0al (2006) Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest. EMBO J 25: 5250\u20135259","journal-title":"EMBO J"},{"key":"42_CR69","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1084\/jem.194.6.809","volume":"194","author":"CG Lee","year":"2001","unstructured":"Lee CG, Homer R, Zhu Z et\u00a0al (2001) Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med 194: 809\u2013821","journal-title":"J Exp Med"},{"key":"42_CR70","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1146\/annurev.iy.11.040193.000541","volume":"11","author":"RI Lehrer","year":"1993","unstructured":"Lehrer RI, Lichtenstein AK, Ganz T (1993) Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol 11: 105\u2013128","journal-title":"Annu Rev Immunol"},{"key":"42_CR71","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/1521-4141(200206)32:6<1605::AID-IMMU1605>3.0.CO;2-6","volume":"32","author":"C Lienhardt","year":"2002","unstructured":"Lienhardt C, Azzurri A, Amedei A et\u00a0al (2002) Active tuberculosis in Africa is associated with reduced Th1 and increased Th2 activity in vivo. Eur J Immunol 32: 1605\u20131613","journal-title":"Eur J Immunol"},{"key":"42_CR72","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1128\/IAI.64.4.1351-1356.1996","volume":"64","author":"Y Lin","year":"1996","unstructured":"Lin Y, Zhang M, Hofman FM et\u00a0al (1996) Absence of a prominent Th2 cytokine response in human tuberculosis. Infect Immun 64: 1351\u20131356","journal-title":"Infect Immun"},{"key":"42_CR73","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0378-1119(99)00136-5","volume":"233","author":"R Linzmeier","year":"1999","unstructured":"Linzmeier R, Ho CH, Hoang BV et\u00a0al (1999) A 450-kb contig of defensin genes on human chromosome 8p23. Gene 233: 205\u2013211","journal-title":"Gene"},{"key":"42_CR74","doi-asserted-by":"crossref","first-page":"5243","DOI":"10.1073\/pnas.94.10.5243","volume":"94","author":"JD MacMicking","year":"1997","unstructured":"MacMicking JD, North RJ, LaCourse R et\u00a0al (1997) Identification of nitric oxide synthase as a protective locus in human tuberculosis. Proc Natl Acad Sci USA 94: 5243\u20135248","journal-title":"Proc Natl Acad Sci USA"},{"key":"42_CR75","doi-asserted-by":"crossref","first-page":"6843","DOI":"10.4049\/jimmunol.162.11.6843","volume":"162","author":"I Malhotra","year":"1999","unstructured":"Malhotra I, Mungai P, Wamachi A et\u00a0al (1999) Helminth-and Bacillus Calmette-Guerin-induced immunity in children sensitized in utero to filariasis and schistosomiasis. J Immunol 162: 6843\u20136848","journal-title":"J Immunol"},{"key":"42_CR76","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1165\/ajrcmb.24.2.4274","volume":"24","author":"A Marchant","year":"2001","unstructured":"Marchant A, Amedei A, Azzurri A et\u00a0al (2001) Polarization of PPD-Specific T-cell response of patients with tuberculosis from Th0 to Th1 profile after successful antimycobacterial therapy or in vitro conditioning with interferon-alpha or interleukin-12. Am J Respir Cell Mol Biol 24: 187\u2013194","journal-title":"Am J Respir Cell Mol Biol"},{"key":"42_CR77","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.tube.2007.10.004","volume":"88","author":"E Martinez Cordero","year":"2008","unstructured":"Martinez Cordero E, Gonz\u00e1lez MM, Aguilar LD et\u00a0al (2008) Alpha-1-acid glycoprotein, its local production and immunopathological participation in experimental pulmonary tuberculosis. Tuberculosis 88: 203\u2013211","journal-title":"Tuberculosis"},{"key":"42_CR78","doi-asserted-by":"crossref","first-page":"2872","DOI":"10.1128\/IAI.72.5.2872-2878.2004","volume":"72","author":"BH Miller","year":"2004","unstructured":"Miller BH, Fratti RA, Poschet JF et\u00a0al (2004) Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection. Infect Immun 72: 2872\u20132878","journal-title":"Infect Immun"},{"key":"42_CR79","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1128\/IAI.64.3.926-932.1996","volume":"64","author":"Y Miyakawa","year":"1996","unstructured":"Miyakawa Y, Ratnakar P, Rao AG et\u00a0al (1996) In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis. Infect Immun 64: 926\u2013932","journal-title":"Infect Immun"},{"key":"42_CR80","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1084\/jem.177.6.1675","volume":"177","author":"AL Moreira","year":"1993","unstructured":"Moreira AL, Sampaio EP, Zmuidzinas A et\u00a0al (1993) Thalidomide exerts its inhibitory effect on tumor necrosis factor by enhancing mRNA degradation. J Exp Med 177: 1675\u20131680","journal-title":"J Exp Med"},{"key":"42_CR81","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1128\/IAI.55.9.2037-2041.1987","volume":"55","author":"I Muller","year":"1987","unstructured":"Muller I, Cobbold SP, Waldmann H et\u00a0al (1987) Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells. Infect Immun 55: 2037\u20132041","journal-title":"Infect Immun"},{"key":"42_CR82","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1084\/jem.183.5.2293","volume":"183","author":"S Nicholson","year":"1996","unstructured":"Nicholson S, Bonecini-Almeida Mda G, Lapae Silva JR et\u00a0al (1996) Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J Exp Med 183: 2293\u20132302","journal-title":"J Exp Med"},{"key":"42_CR83","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nm0804-801","volume":"10","author":"A O\u2019Garra","year":"2004","unstructured":"O\u2019Garra A, Vieira P (2004) Regulatory T cells and mechanisms of immune system control. Nat Med 10: 801\u2013805","journal-title":"Nat Med"},{"key":"42_CR84","doi-asserted-by":"crossref","first-page":"5448","DOI":"10.4049\/jimmunol.160.11.5448","volume":"160","author":"M Oddo","year":"1998","unstructured":"Oddo M, Renno T, Attinger A et\u00a0al (1998) Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis. J Immunol 160: 5448\u20135454","journal-title":"J Immunol"},{"key":"42_CR85","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1128\/IAI.60.11.4720-4725.1992","volume":"60","author":"K Ogata","year":"1992","unstructured":"Ogata K, Linzer BA, Zuberi RI et\u00a0al (1992) Activity of defensins from human neutrophilic granulocytes against Mycobacterium avium-Mycobacterium intracellulare. Infect Immun 60: 4720\u20134725","journal-title":"Infect Immun"},{"key":"42_CR86","first-page":"599","volume":"59","author":"JK Onwubalili","year":"1986","unstructured":"Onwubalili JK, Scott GM, Smith H (1986) Acute respiratory distress related to chemotherapy of advanced pulmonary tuberculosis a study of two cases and review of the literature. Q J Med 59: 599\u2013610","journal-title":"Q J Med"},{"key":"42_CR87","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.0959-9673.2004.00381.x","volume":"85","author":"A Pedroza-Gonzalez","year":"2004","unstructured":"Pedroza-Gonzalez A, Garcia-Romo GS, Aguilar-Leon D et\u00a0al (2004) In situ analysis of lung antigen-presenting cells during murine pulmonary infection with virulent Mycobacterium tuberculosis. Int J Exp Pathol 85: 135\u2013145","journal-title":"Int J Exp Pathol"},{"key":"42_CR88","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1128\/IAI.63.4.1598-1602.1995","volume":"63","author":"PK Peterson","year":"1995","unstructured":"Peterson PK, Gekker G, Hu S et\u00a0al (1995) CD14 receptor-mediated uptake of nonopsonized Mycobacterium tuberculosis by human microglia. Infect Immun 63: 1598\u20131602","journal-title":"Infect Immun"},{"key":"42_CR89","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0167-5699(91)90064-Z","volume":"12","author":"RP Phipps","year":"1991","unstructured":"Phipps RP, Stein SH, Roper RL (1991) A new view of prostaglandin E regulation of the immune response. Immunol Today 12: 349\u2013352","journal-title":"Immunol Today"},{"key":"42_CR90","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1365-2265.1994.tb03933.x","volume":"40","author":"FA Post","year":"1994","unstructured":"Post FA, Soule SG, Willcox PA et\u00a0al (1994) The spectrum of endocrine dysfunction in active tuberculosis. Clin Endocrinol 40: 367\u2013371","journal-title":"Clin Endocrinol"},{"key":"42_CR91","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.4049\/jimmunol.175.3.1805","volume":"175","author":"AK Randhawa","year":"2005","unstructured":"Randhawa AK, Ziltener HJ, Merzaban JS et\u00a0al (2005) CD43 is required for optimal growth inhibition of Mycobacterium tuberculosis in macrophages and in mice. J Immunol 175: 1805\u20131812","journal-title":"J Immunol"},{"key":"42_CR92","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1046\/j.1365-2567.2002.01403.x","volume":"106","author":"J Rangel Moreno","year":"2002","unstructured":"Rangel Moreno J, Estrada Garcia I, De La LuzGarcia Hernandez M. et\u00a0al (2002) The role of prostaglandin E2 in the immunopathogenesis of experimental pulmonary tuberculosis. Immunology 106: 257\u2013266","journal-title":"Immunology"},{"key":"42_CR93","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1365-2249.2006.03012.x","volume":"143","author":"R Reljic","year":"2006","unstructured":"Reljic R, Clark SO, Williams A et\u00a0al (2006) Intranasal IFN-gamma extends passive IgA antibody protection of mice against Mycobacterium tuberculosis lung infection. Clin Exp Immunol 143: 467\u2013473","journal-title":"Clin Exp Immunol"},{"key":"42_CR94","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.4049\/jimmunol.168.6.2634","volume":"168","author":"M Relloso","year":"2002","unstructured":"Relloso M, Puig-Kroger A, Pello OM et\u00a0al (2002) DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents. J Immunol 168: 2634\u20132643","journal-title":"J Immunol"},{"key":"42_CR95","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1365-2249.2006.03027.x","volume":"144","author":"R Ribeiro-Rodriguez","year":"2006","unstructured":"Ribeiro-Rodriguez R, Resende Co T, Rojas R et\u00a0al (2006) A role for CD4+ CD25+ T cells in regulation of the immune response during human tuberculosis. Clin Exp Immunol 144: 25\u201334","journal-title":"Clin Exp Immunol"},{"key":"42_CR96","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/eji.200535202","volume":"36","author":"VA Rios-Barrera","year":"2006","unstructured":"Rios-Barrera VA, Campos-Pe\u00f1a V, Aguilar-Leon D et\u00a0al (2006) Macrophage and T lymphocyte apoptosis during experimental pulmonary tuberculosis: Their relationship to mycobacterial virulence. Eur J Immunol 36: 345\u2013353","journal-title":"Eur J Immunol"},{"key":"42_CR97","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/j.1365-3083.2008.02088.x","volume":"67","author":"B Rivas-Santiago","year":"2008","unstructured":"Rivas-Santiago B, Contreras JC, Sada E et\u00a0al (2008) The potencial role of lung epithelial cells and beta defensins in experimental latent tuberculosis. Scan J Immunol 67: 448\u2013452","journal-title":"Scan J Immunol"},{"key":"42_CR98","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1086\/506454","volume":"194","author":"B Rivas-Santiago","year":"2006","unstructured":"Rivas-Santiago B, Sada E, Tsutsumi V (2006) beta-Defensin gene expression during the course of experimental tuberculosis infection. J Infect Dis 194: 697\u2013701","journal-title":"J Infect Dis"},{"key":"42_CR99","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.1128\/IAI.73.8.4505-4511.2005","volume":"73","author":"B Rivas-Santiago","year":"2005","unstructured":"Rivas-Santiago B, Schwander SK, Sarabia C et\u00a0al (2005) Human {beta}-defensin 2 is expressed and associated with Mycobacterium tuberculosis during infection of human alveolar epithelial cells. Infect Immun 73: 4505\u20134511","journal-title":"Infect Immun"},{"key":"42_CR100","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1086\/511277","volume":"195","author":"T Roberts","year":"2007","unstructured":"Roberts T, Beyers N, Aguirre A et\u00a0al (2007) Immunosuppression during active tuberculosis is characterized by decreased interferon gamma production and CD25 expression with elevated for knead box P3, transforming growth factor beta and interleukin 4 in RNA levels. J Infect Dis 195: 870\u2013878","journal-title":"J Infect Dis"},{"key":"42_CR101","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/j.1749-6632.2000.tb05457.x","volume":"917","author":"G Rook","year":"2000","unstructured":"Rook G, Baker R, Walker B et\u00a0al (2000) Local regulation of glucocorticoid activity in sites of inflammation. Insights from the study of tuberculosis. Ann NY Acad Sci 917: 913\u2013922","journal-title":"Insights from the study of tuberculosis. Ann NY Acad Sci"},{"key":"42_CR102","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nri1666","volume":"5","author":"GA Rook","year":"2005","unstructured":"Rook GA, Dheda K, Zumla A (2005) Immune responses in developing countries; implications for new vaccines. Nat Rev Immunol 5: 661\u2013667","journal-title":"Nat Rev Immunol"},{"key":"42_CR103","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1146\/annurev.micro.50.1.259","volume":"50","author":"GA Rook","year":"1996","unstructured":"Rook GA, Hernandez-Pando R (1996) The pathogenesis of tuberculosis. Ann Rev Microbiol 50: 259\u2013284","journal-title":"Ann Rev Microbiol"},{"key":"42_CR104","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.it.2004.06.005","volume":"25","author":"GA Rook","year":"2004","unstructured":"Rook GA, Hernandez-Pando R, Dheda K et\u00a0al (2004) IL-4 in tuberculosis: implications for vaccine design. Trends Immunol 25: 483\u2013488","journal-title":"Trends Immunol"},{"key":"42_CR105","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0167-5699(94)90075-2","volume":"15","author":"GA Rook","year":"1994","unstructured":"Rook GA, Hernandez-Pando R, Lightman S (1994) Hormones, peripherally activated prohormones and regulation of the Th1\/Th2 balance. Immunol Today 15: 301\u2013303","journal-title":"Immunol Today"},{"key":"42_CR106","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/qjmed\/89.5.333","volume":"89","author":"GA Rook","year":"1996","unstructured":"Rook GA, Honour J, Kon OM et\u00a0al (1996) Urinary adrenal steroid metabolites in tuberculosis \u2013 a new clue to pathogenesis. Q J Med 89: 333\u2013342","journal-title":"Q J Med"},{"key":"42_CR107","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1086\/518937","volume":"196","author":"GA Rook","year":"2007","unstructured":"Rook GA, Lowrie DB, Hernandez-Pando R (2007) Immunotherapeutics for tuberculosis in experimental animals: Is there a common pathway activated by effective protocols. J Infect Dis 196: 191\u2013198","journal-title":"J Infect Dis"},{"key":"42_CR108","doi-asserted-by":"crossref","first-page":"5673","DOI":"10.1128\/IAI.62.12.5673-5678.1994","volume":"62","author":"FO Sanchez","year":"1994","unstructured":"Sanchez FO, Rodriguez JI, Agudelo G et\u00a0al (1994) Immune responsiveness and lymphokine production in patients with tuberculosis and healthy controls. Infect Immun 62: 5673\u20135678","journal-title":"Infect Immun"},{"key":"42_CR109","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0041-3879(90)90041-6","volume":"71","author":"GR Sarma","year":"1990","unstructured":"Sarma GR, Immanuel C, Ramachandran G et\u00a0al (1990) Adrenocortical function in patients with pulmonary tuberculosis. Tubercle 71: 277\u2013282","journal-title":"Tubercle"},{"key":"42_CR110","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1084\/jem.192.3.347","volume":"192","author":"CA Scanga","year":"2000","unstructured":"Scanga CA, Mohan VP, Yu K et\u00a0al (2000) Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2. J Exp Med 192: 347\u2013358","journal-title":"J Exp Med"},{"key":"42_CR111","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1093\/infdis\/168.4.1056","volume":"168","author":"V Schauf","year":"1993","unstructured":"Schauf V, Rom WN, Smith KA et\u00a0al (1993) Cytokine gene activation and modified responsiveness to interleukin-2 in the blood of tuberculosis patients. J Infect Dis 168: 1056\u20131059","journal-title":"J Infect Dis"},{"key":"42_CR112","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.4049\/jimmunol.150.7.2920","volume":"150","author":"LS Schlesinger","year":"1993","unstructured":"Schlesinger LS (1993) Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptors. J Immunol 150: 2920\u20132930","journal-title":"J Immunol"},{"key":"42_CR113","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.4049\/jimmunol.144.7.2771","volume":"144","author":"LS Schlesinger","year":"1990","unstructured":"Schlesinger LS, Bellinger-Kawahara CG, Payne NR et\u00a0al (1990) Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3. J Immunol 144: 2771\u20132780","journal-title":"J Immunol"},{"key":"42_CR114","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0163-4453(90)90669-Y","volume":"21","author":"GM Scott","year":"1990","unstructured":"Scott GM, Murphy PG, Gemidjioglu ME (1990) Predicting deterioration of treated tuberculosis by corticosteroid reserve and C-reactive protein. J Infect 21: 61\u201369","journal-title":"J Infect"},{"key":"42_CR115","doi-asserted-by":"crossref","unstructured":"Seah GT, Scott GM, Rook GA (2000) Type 2 cytokine gene activation and its relationship to extent of disease in patients with tuberculosis. J Infect Dis 181: 385\u2013359","DOI":"10.1086\/315200"},{"key":"42_CR116","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1128\/IAI.55.9.2281-2286.1987","volume":"55","author":"ME Selsted","year":"1987","unstructured":"Selsted ME, Harwig SS (1987) Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin. Infect Immun 55: 2281\u20132286","journal-title":"Infect Immun"},{"key":"42_CR117","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1128\/IAI.49.1.202-206.1985","volume":"49","author":"ME Selsted","year":"1985","unstructured":"Selsted ME, Szklarek D, Ganz T et\u00a0al (1985) Activity of rabbit leukocyte peptides against Candida albicans. Infect Immun 49: 202\u2013206","journal-title":"Infect Immun"},{"key":"42_CR118","doi-asserted-by":"crossref","first-page":"3980","DOI":"10.1128\/IAI.67.8.3980-3988.1999","volume":"67","author":"NV Serbina","year":"1999","unstructured":"Serbina NV, Flynn JL (1999) Early emergence of CD8(+) T cells primed for production of type 1 cytokines in the lungs of Mycobacterium tuberculosis-infected mice. Infect Immun 67: 3980\u20133988","journal-title":"Infect Immun"},{"key":"42_CR119","doi-asserted-by":"crossref","first-page":"6991","DOI":"10.4049\/jimmunol.167.12.6991","volume":"167","author":"NV Serbina","year":"2001","unstructured":"Serbina NV, Lazarevic V, Flynn JL (2001) CD4(+) T cells are required for the development of cytotoxic CD8(+) T cells during Mycobacterium tuberculosis infection. J Immunol 167: 6991\u20137000","journal-title":"J Immunol"},{"key":"42_CR120","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1128\/AAC.45.2.639-640.2001","volume":"45","author":"S Sharma","year":"2001","unstructured":"Sharma S, Verma I, Khuller GK (2001) Therapeutic potential of human neutrophil peptide 1 against experimental tuberculosis. Antimicrob Agents Chemother 45: 639\u2013640","journal-title":"Antimicrob Agents Chemother"},{"key":"42_CR121","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1136\/bmj.307.6907.759","volume":"307","author":"DP Spence","year":"1993","unstructured":"Spence DP, Hotchkiss J, Williams CS et\u00a0al (1993) Tuberculosis and poverty. Br Med J 307: 759\u2013761","journal-title":"Br Med J"},{"key":"42_CR122","first-page":"160","volume":"68","author":"RM Steinman","year":"2001","unstructured":"Steinman RM (2001) Dendritic cells and the control of immunity: enhancing the efficiency of antigen presentation. Mt Sinai J Med 68: 160\u2013166","journal-title":"Mt Sinai J Med"},{"key":"42_CR123","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1126\/science.282.5386.121","volume":"282","author":"S Stenger","year":"1998","unstructured":"Stenger S, Hanson DA, Teitelbaum R et\u00a0al (1998a) An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282: 121\u2013125","journal-title":"Science"},{"key":"42_CR124","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1126\/science.276.5319.1684","volume":"276","author":"S Stenger","year":"1997","unstructured":"Stenger S, Mazzaccaro RJ, Uyemura K et\u00a0al (1997) Differential effects of cytolytic T cell subsets on intracellular infection. Science 276: 1684\u20131687","journal-title":"Science"},{"key":"42_CR125","doi-asserted-by":"crossref","first-page":"3582","DOI":"10.4049\/jimmunol.161.7.3582","volume":"161","author":"S Stenger","year":"1998","unstructured":"Stenger S, Niazi KR, Modlin RL (1998b) Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis. J Immunol 161: 3582\u20133588","journal-title":"J Immunol"},{"key":"42_CR126","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/ni1122","volume":"5","author":"P Stock","year":"2004","unstructured":"Stock P, Akbari O, Berry G et\u00a0al (2004) Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper reactivity. Nat Immunol 5: 1149\u20131156","journal-title":"Nat Immunol"},{"key":"42_CR127","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1126\/science.8303277","volume":"263","author":"S Sturgill-Koszycki","year":"1994","unstructured":"Sturgill-Koszycki S, Schlesinger PH, Chakraborty P et\u00a0al (1994) Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263: 678\u2013681","journal-title":"Science"},{"key":"42_CR128","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1084\/jem.20021468","volume":"197","author":"L Tailleux","year":"2003","unstructured":"Tailleux L, Schwartz O, Herrmann JL et\u00a0al (2003) DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J Exp Med 197: 121\u2013127","journal-title":"J Exp Med"},{"key":"42_CR129","doi-asserted-by":"crossref","first-page":"15688","DOI":"10.1073\/pnas.95.26.15688","volume":"95","author":"R Teitelbaum","year":"1998","unstructured":"Teitelbaum R, Glatman-Freedman A, Chen B et\u00a0al (1998) A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival. Proc Natl Acad Sci USA 95: 15688\u201315693","journal-title":"Proc Natl Acad Sci USA"},{"key":"42_CR130","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1152\/ajplegacy.1956.187.2.399","volume":"187","author":"E Tobach","year":"1956","unstructured":"Tobach E, Bloch H (1956) Effects of crowding prior to and following tuberculous infection. Am J Physiol 187: 399\u2013402","journal-title":"Am J Physiol"},{"key":"42_CR131","doi-asserted-by":"crossref","first-page":"465","DOI":"10.4049\/jimmunol.154.1.465","volume":"154","author":"Z Toossi","year":"1995","unstructured":"Toossi Z, Gogate P, Shiratsuchi H et\u00a0al (1995) Enhanced production of TGF-beta by blood monocytes from patients with active tuberculosis and presence of TGF-beta in tuberculous granulomatous lung lesions. J Immunol 154: 465\u2013473","journal-title":"J Immunol"},{"key":"42_CR132","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1126\/science.288.5465.522","volume":"288","author":"SJ Turley","year":"2000","unstructured":"Turley SJ, Inaba K, Garrett WS et\u00a0al (2000) Transport of peptide-MHC class II complexes in developing dendritic cells. Science 288: 522\u2013527","journal-title":"Science"},{"key":"42_CR133","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1086\/315325","volume":"181","author":"R Crevel van","year":"2000","unstructured":"van Crevel R, Karyadi E, Preyers F et\u00a0al (2000) Increased production of interleukin 4 by CD4+ and CD8+ T cells from patients with tuberculosis is related to the presence of pulmonary cavities. J Infect Dis 181: 1194\u20131197","journal-title":"J Infect Dis"},{"key":"42_CR134","doi-asserted-by":"crossref","first-page":"13326","DOI":"10.1074\/jbc.272.20.13326","volume":"272","author":"LE Via","year":"1997","unstructured":"Via LE, Deretic D, Ulmer RJ et\u00a0al (1997) Arrest of mycobacterial phagosome maturation is caused by a block in vescicle fusion between stages controlled by rab5 and rab7. J Biol Chem 272: 13326\u201313331","journal-title":"J Biol Chem"},{"key":"42_CR135","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.4049\/jimmunol.163.7.3936","volume":"163","author":"MI Wickremasinghe","year":"1999","unstructured":"Wickremasinghe MI, Thomas LH, Friedland JS (1999) Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-kappa B-dependent network. J Immunol 163: 3936\u20133947","journal-title":"J Immunol"},{"key":"42_CR136","doi-asserted-by":"crossref","first-page":"6505","DOI":"10.1128\/IAI.68.11.6505-6508.2000","volume":"68","author":"KA Wilkinson","year":"2000","unstructured":"Wilkinson KA, Martin TD, Reba SM et\u00a0al (2000) Latency-associated peptide of transforming growth factor beta enhances mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL\/6 mice. Infect Immun 68: 6505\u20136508","journal-title":"Infect Immun"},{"key":"42_CR137","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1365-2567.2004.01809.x","volume":"111","author":"A Williams","year":"2004","unstructured":"Williams A, Reljic R, Naylor I et\u00a0al (2004) Passive protection with immunoglobulin A antibodies against tuberculous early infection of the lungs. Immunology 111: 328\u2013333","journal-title":"Immunology"},{"key":"42_CR138","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0041-3879(89)90021-4","volume":"70","author":"AJ Yong","year":"1989","unstructured":"Yong AJ, Grange JM, Tee RD et\u00a0al (1989) Total and anti-mycobacterial IgE levels in serum from patients with tuberculosis and leprosy. Tubercle 70: 273\u2013279","journal-title":"Tubercle"},{"key":"42_CR139","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1165\/ajrcmb.15.6.8969271","volume":"15","author":"S Zimmerli","year":"1996","unstructured":"Zimmerli S, Edwards S, Ernst JD (1996) Selective receptor blockade during phagocytosis does not alter the survival and growth of Mycobacterium tuberculosis in human macrophages. Am J Respir Cell Mol Biol 15: 760\u2013770","journal-title":"Am J Respir Cell Mol Biol"},{"key":"42_CR140","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/eji.1830190213","volume":"19","author":"SH Zuckerman","year":"1989","unstructured":"Zuckerman SH, Shellhaas J, Butler LD (1989) Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary-adrenal axis. Eur J Immunol 19: 301\u2013305","journal-title":"Eur J Immunol"}],"container-title":["Archivum Immunologiae et Therapiae Experimentalis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00005-009-0042-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00005-009-0042-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00005-009-0042-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T20:46:53Z","timestamp":1704228413000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00005-009-0042-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,18]]},"references-count":140,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["42"],"URL":"https:\/\/doi.org\/10.1007\/s00005-009-0042-9","relation":{},"ISSN":["0004-069X","1661-4917"],"issn-type":[{"value":"0004-069X","type":"print"},{"value":"1661-4917","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,18]]}}}