{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T13:48:01Z","timestamp":1758980881301,"version":"3.37.3"},"reference-count":59,"publisher":"Walter de Gruyter GmbH","issue":"6","license":[{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico (CL)","doi-asserted-by":"publisher","award":["1130615"],"award-info":[{"award-number":["1130615"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Iniciativa Cient\u00edfica Milenio","award":["P09\/016-F"],"award-info":[{"award-number":["P09\/016-F"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch. Immunol. Ther. Exp."],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s00005-016-0400-3","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T14:05:45Z","timestamp":1462370745000},"page":"435-442","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Humoral and Cellular Autoreactivity to Epidermal Proteins in Atopic Dermatitis"],"prefix":"10.2478","volume":"64","author":[{"given":"Cristi\u00e1n","family":"Navarrete-Dechent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"P\u00e9rez-Mateluna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Silva-Valenzuela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristi\u00e1n","family":"Vera-Kellet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7904-262X","authenticated-orcid":false,"given":"Arturo","family":"Borzutzky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2016,5,4]]},"reference":[{"key":"400_CR1","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.4049\/jimmunol.175.2.1286","volume":"175","author":"KJ Aichberger","year":"2005","unstructured":"Aichberger KJ, Mittermann I, Reininger R et al (2005) Hom s 4, an IgE-reactive autoantigen belonging to a new subfamily of calcium-binding proteins, can induce Th cell type 1-mediated autoreactivity. J Immunol 175:1286\u20131294","journal-title":"J Immunol"},{"key":"400_CR2","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1038\/jid.2008.80","volume":"128","author":"S Altrichter","year":"2008","unstructured":"Altrichter S, Kriehuber E, Moser J et al (2008) Serum IgE autoantibodies target keratinocytes in patients with atopic dermatitis. J Invest Dermatol 128:2232\u20132239","journal-title":"J Invest Dermatol"},{"key":"400_CR3","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1001\/archderm.1977.01640060076008","volume":"113","author":"R Aly","year":"1977","unstructured":"Aly R, Maibach HI, Shinefield HR (1977) Microbial flora of atopic dermatitis. Arch Dermatol 113:780\u2013782","journal-title":"Arch Dermatol"},{"issue":"92\u201399","key":"400_CR4","first-page":"94","volume":"128","author":"H Balaji","year":"2011","unstructured":"Balaji H, Heratizadeh A, Wichmann K et al (2011) Malassezia sympodialis thioredoxin-specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis. J Allergy Clin Immunol 128(92\u201399):94","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.clindermatol.2011.08.007","volume":"30","author":"A Baroni","year":"2012","unstructured":"Baroni A, Buommino E, De Gregorio V et al (2012) Structure and function of the epidermis related to barrier properties. Clin Dermatol 30:257\u2013262","journal-title":"Clin Dermatol"},{"key":"400_CR6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.5021\/ad.2010.22.2.125","volume":"22","author":"T Bieber","year":"2010","unstructured":"Bieber T (2010) Atopic dermatitis. Ann Dermatol 22:125\u2013137","journal-title":"Atopic dermatitis. Ann Dermatol"},{"key":"400_CR7","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/1346-8138.12464","volume":"41","author":"F Cipriani","year":"2014","unstructured":"Cipriani F, Ricci G, Leoni MC et al (2014) Autoimmunity in atopic dermatitis: biomarker or simply epiphenomenon? J Dermatol 41:569\u2013576","journal-title":"J Dermatol"},{"key":"400_CR8","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1159\/000365075","volume":"229","author":"C Coutanceau","year":"2014","unstructured":"Coutanceau C, Stalder JF (2014) Analysis of correlations between patient-oriented SCORAD (PO-SCORAD) and other assessment scores of atopic dermatitis severity and quality of life. Dermatology 229:248\u2013255","journal-title":"Dermatology"},{"key":"400_CR9","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jaad.2013.10.010","volume":"70","author":"LF Eichenfield","year":"2014","unstructured":"Eichenfield LF, Tom WL, Chamlin SL et al (2014) Guidelines of care for the management of atopic dermatitis: section\u00a01. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol 70:338\u2013351","journal-title":"J Am Acad Dermatol"},{"key":"400_CR10","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1398-9995.2006.01076.x","volume":"61","author":"R Folster-Holst","year":"2006","unstructured":"Folster-Holst R, Pape M, Buss YL et al (2006) Low prevalence of the intrinsic form of atopic dermatitis among adult patients. Allergy 61:629\u2013632","journal-title":"Allergy"},{"key":"400_CR11","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/all.12112","volume":"68","author":"D Garmhausen","year":"2013","unstructured":"Garmhausen D, Hagemann T, Bieber T et al (2013) Characterization of different courses of atopic dermatitis in adolescent and adult patients. Allergy 68:498\u2013506","journal-title":"Allergy"},{"key":"400_CR12","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/bjd.13695","volume":"173","author":"F Guarneri","year":"2015","unstructured":"Guarneri F, Costa C, Foti C et al (2015) Frequency of autoallergy to manganese superoxide dismutase in atopic dermatitis patients: experience of three Italian dermatology centers. Br J Dermatol 173:559\u2013562","journal-title":"Br J Dermatol"},{"key":"400_CR13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0021-8707(41)90008-4","volume":"13","author":"SF Hampton","year":"1941","unstructured":"Hampton SF, Cooke RA (1941) The sensitivity of man to human dander, with particular reference to eczema (allergic dermatitis). J Allergy 13:63\u201376","journal-title":"J Allergy"},{"key":"400_CR14","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0140-6736(63)90171-5","volume":"2","author":"N Hashem","year":"1963","unstructured":"Hashem N, Hirschhorn K, Sedlis E et al (1963) Infantile eczema. Evidence of autoimmunity to human skin. Lancet 2:269\u2013270","journal-title":"Lancet"},{"key":"400_CR15","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1365-2133.2010.10090.x","volume":"164","author":"A Heratizadeh","year":"2011","unstructured":"Heratizadeh A, Mittermann I, Balaji H et al (2011) The role of T-cell reactivity towards the autoantigen \u03b1-NAC in atopic dermatitis. Br J Dermatol 164:316\u2013324","journal-title":"Br J Dermatol"},{"key":"400_CR16","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1272\/jnms.76.300","volume":"76","author":"N Higashi","year":"2009","unstructured":"Higashi N, Niimi Y, Aoki M et al (2009) Clinical features of antinuclear antibody-positive patients with atopic dermatitis. J Nippon Med Sch 76:300\u2013307","journal-title":"J Nippon Med Sch"},{"key":"400_CR17","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s40629-015-0037-5","volume":"24","author":"S Hradetzky","year":"2015","unstructured":"Hradetzky S, Werfel T, R\u00f6sner LM (2015) Autoallergy in atopic dermatitis. Allergo J Int 24:16\u201322","journal-title":"Allergo J Int"},{"key":"400_CR18","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.jaci.2004.01.778","volume":"113","author":"S Illi","year":"2004","unstructured":"Illi S, von Mutius E, Lau S et al (2004) The natural course of atopic dermatitis from birth to age 7\u00a0years and the association with asthma. J Allergy Clin Immunol 113:925\u2013931","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR19","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jaci.2011.05.005","volume":"128","author":"EA James","year":"2011","unstructured":"James EA, Kwok WW (2011) Autoreactive CD4(+) T cells in patients with atopic dermatitis. J Allergy Clin Immunol 128:100\u2013101","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR20","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1067\/mai.2002.123303","volume":"109","author":"T Kinaciyan","year":"2002","unstructured":"Kinaciyan T, Natter S, Kraft D et al (2002) IgE autoantibodies monitored in a patient with atopic dermatitis under cyclosporin A treatment reflect tissue damage. J Allergy Clin Immunol 109:717\u2013719","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR21","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0022-2836(02)00551-X","volume":"320","author":"E Kubo","year":"2002","unstructured":"Kubo E, Fatma N, Sharma P et al (2002) Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF). J Mol Biol 320:1053\u20131063","journal-title":"J Mol Biol"},{"key":"400_CR22","first-page":"16","volume":"6","author":"J Levin","year":"2013","unstructured":"Levin J, Friedlander SF, Del Rosso JQ (2013) Atopic dermatitis and the stratum corneum: part 1: the role of filaggrin in the stratum corneum barrier and atopic skin. J Clin Aesthet Dermatol 6:16\u201322","journal-title":"J Clin Aesthet Dermatol"},{"key":"400_CR23","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1111\/j.1742-1241.2006.01047.x","volume":"60","author":"S Lewis-Jones","year":"2006","unstructured":"Lewis-Jones S (2006) Quality of life and childhood atopic dermatitis: the misery of living with childhood eczema. Int J Clin Pract 60:984\u2013992","journal-title":"Int J Clin Pract"},{"key":"400_CR24","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1046\/j.1523-1747.2003.12359.x","volume":"121","author":"KC Madison","year":"2003","unstructured":"Madison KC (2003) Barrier function of the skin: \u201cla raison d\u2019\u00eatre\u201d of the epidermis. J Invest Dermatol 121:231\u2013241","journal-title":"J Invest Dermatol"},{"key":"400_CR25","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1038\/sj.jid.5701195","volume":"128","author":"I Mittermann","year":"2008","unstructured":"Mittermann I, Reininger R, Zimmermann M et al (2008) The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma. J Invest Dermatol 128:1451\u20131459","journal-title":"J Invest Dermatol"},{"key":"400_CR26","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1001\/jamadermatol.2014.3324","volume":"151","author":"GC Mohan","year":"2015","unstructured":"Mohan GC, Silverberg JI (2015) Association of vitiligo and alopecia areata with atopic dermatitis: a systematic review and meta-analysis. JAMA Dermatol 151:522\u2013528","journal-title":"JAMA Dermatol"},{"key":"400_CR27","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1111\/all.12619","volume":"70","author":"CG Mortz","year":"2015","unstructured":"Mortz CG, Andersen KE, Dellgren C et al (2015) Atopic dermatitis from adolescence to adulthood in the TOACS cohort: prevalence, persistence and comorbidities. Allergy 70:836\u2013845","journal-title":"Allergy"},{"key":"400_CR28","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1096\/fasebj.12.14.1559","volume":"12","author":"S Natter","year":"1998","unstructured":"Natter S, Seiberler S, Hufnagl P et al (1998) Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients. FASEB J 12:1559\u20131569","journal-title":"FASEB J"},{"issue":"6 Pt","key":"400_CR29","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1067\/mai.2000.107039","volume":"105","author":"RL Ochs","year":"2000","unstructured":"Ochs RL, Muro Y, Si Y et al (2000) Autoantibodies to DFS 70\u00a0kd\/transcription coactivator p75 in atopic dermatitis and other conditions. J Allergy Clin Immunol 105(6 Pt):1211\u20131220","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR30","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jaut.2004.07.004","volume":"23","author":"M Okamoto","year":"2004","unstructured":"Okamoto M, Ogawa Y, Watanabe A et al (2004) Autoantibodies to DFS70\/LEDGF are increased in alopecia areata patients. J Autoimmun 23:257\u2013266","journal-title":"J Autoimmun"},{"key":"400_CR31","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1056\/NEJMoa021481","volume":"347","author":"PY Ong","year":"2002","unstructured":"Ong PY, Ohtake T, Brandt C et al (2002) Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med 347:1151\u20131160","journal-title":"N Engl J Med"},{"key":"400_CR32","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1111\/j.1600-0625.2009.00842.x","volume":"18","author":"RL Orfali","year":"2009","unstructured":"Orfali RL, Sato MN, Takaoka R et al (2009) Atopic dermatitis in adults: evaluation of peripheral blood mononuclear cells proliferation response to Staphylococcus aureus enterotoxins A and B and analysis of interleukin-18 secretion. Exp Dermatol 18:628\u2013633","journal-title":"Exp Dermatol"},{"key":"400_CR33","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1111\/ijd.12533","volume":"54","author":"RL Orfali","year":"2015","unstructured":"Orfali RL, Sato MN, Santos VG et al (2015) Staphylococcal enterotoxin B induces specific IgG4 and IgE antibody serum levels in atopic dermatitis. Int J Dermatol 54:898\u2013904","journal-title":"Int J Dermatol"},{"key":"400_CR34","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/cea.12495","volume":"45","author":"W Peng","year":"2015","unstructured":"Peng W, Novak N (2015) Pathogenesis of atopic dermatitis. Clin Exp Allergy 45:566\u2013574","journal-title":"Clin Exp Allergy"},{"key":"400_CR35","doi-asserted-by":"crossref","first-page":"150","DOI":"10.2340\/0001555561150153","volume":"61","author":"G Rajka","year":"1981","unstructured":"Rajka G, Aly R, Bayles C et al (1981) The effect of short-term occlusion on the cutaneous flora in atopic dermatitis and psoriasis. Acta Derm Venereol 61:150\u2013153","journal-title":"Acta Derm Venereol"},{"key":"400_CR36","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/pde.12372","volume":"31","author":"K Ress","year":"2014","unstructured":"Ress K, Annus T, Putnik U et al (2014) Celiac disease in children with atopic dermatitis. Pediatr Dermatol 31:483\u2013488","journal-title":"Pediatr Dermatol"},{"key":"400_CR37","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/ijd.12535","volume":"54","author":"K Ress","year":"2015","unstructured":"Ress K, Metsk\u00fcla K, Annus T et al (2015) Antinuclear antibodies in atopic dermatitis: a cross-sectional study on 346 children. Int J Dermatol 54:24\u201328","journal-title":"Int J Dermatol"},{"key":"400_CR38","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jaut.2005.01.010","volume":"24","author":"G Ricci","year":"2005","unstructured":"Ricci G, Maldini MC, Patrizi A et al (2005) Anticardiolipin antibodies in children with atopic dermatitis. J Autoimmun 24:221\u2013225","journal-title":"J Autoimmun"},{"key":"400_CR39","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1824-7288-40-46","volume":"40","author":"G Ricci","year":"2014","unstructured":"Ricci G, Dondi A, Neri I et al (2014) Atopic dermatitis phenotypes in childhood. Ital J Pediatr 40:46","journal-title":"Ital J Pediatr"},{"key":"400_CR40","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1111\/j.1468-3083.2012.04635.x","volume":"26","author":"J Ring","year":"2012","unstructured":"Ring J, Alomar A, Bieber T et al (2012) Guidelines for treatment of atopic eczema (atopic dermatitis) part I. J Eur Acad Dermatol Venereol 26:1045\u20131060","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"400_CR41","first-page":"190","volume":"23","author":"Egu\u00edluz-Gracia I Sanchez-Ramon","year":"2013","unstructured":"Sanchez-Ramon Egu\u00edluz-Gracia I, Rodr\u00edguez-Mazariego MES et al (2013) Sequential combined therapy with omalizumab and rituximab: a new approach to severe atopic dermatitis. J Investig Allergol Clin Immunol 23:190\u2013196","journal-title":"J Investig Allergol Clin Immunol"},{"key":"400_CR42","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1046\/j.1365-2133.2000.03832.x","volume":"143","author":"T Schafer","year":"2000","unstructured":"Schafer T, Kramer U, Vieluf D et al (2000) The excess of atopic eczema in East Germany is related to the intrinsic type. Br J Dermatol 143:992\u2013998","journal-title":"Br J Dermatol"},{"key":"400_CR43","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.3899\/jrheum.150567","volume":"42","author":"H Schmeling","year":"2015","unstructured":"Schmeling H, Mahler M, Levy DM et al (2015) Autoantibodies to dense fine speckles in pediatric diseases and controls. J Rheumatol 42:2419\u20132426","journal-title":"J Rheumatol"},{"key":"400_CR44","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.jaci.2005.01.065","volume":"115","author":"P Schmid-Grendelmeier","year":"2005","unstructured":"Schmid-Grendelmeier P, Fl\u00fcckiger S, Disch R et al (2005) IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J Allergy Clin Immunol 115:1068\u20131075","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR45","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1398-9995.2010.02487.x","volume":"66","author":"J Schmitt","year":"2011","unstructured":"Schmitt J, Chen CM, Apfelbacher C et al (2011) Infant eczema, infant sleeping problems, and mental health at 10\u00a0years of age: the prospective birth cohort study LISAplus. Allergy 66:404\u2013411","journal-title":"Allergy"},{"key":"400_CR46","first-page":"159","volume":"114","author":"FV Schultz Larsen","year":"1985","unstructured":"Schultz Larsen FV, Holm NV (1985) Atopic dermatitis in a population based twin series. Concordance rates and heritability estimation. Acta Derm Venereol Suppl 114:159","journal-title":"Acta Derm Venereol Suppl"},{"key":"400_CR47","doi-asserted-by":"crossref","first-page":"20037","DOI":"10.1074\/jbc.M212016200","volume":"278","author":"P Sharma","year":"2003","unstructured":"Sharma P, Fatma N, Kubo E et al (2003) Lens epithelium-derived growth factor relieves transforming growth factor-beta1-induced transcription repression of heat shock proteins in human lens epithelial cells. J Biol Chem 278:20037\u201320046","journal-title":"J Biol Chem"},{"key":"400_CR48","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1006\/bbrc.2001.4887","volume":"283","author":"DP Singh","year":"2001","unstructured":"Singh DP, Fatma N, Kimura A et al (2001) LEDGF binds to heat shock and stress-related element to activate the expression of stress-related genes. Biochem Biophys Res Commun 283:943\u2013955","journal-title":"Biochem Biophys Res Commun"},{"key":"400_CR49","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.anai.2009.10.002","volume":"105","author":"JM Spergel","year":"2010","unstructured":"Spergel JM (2010) From atopic dermatitis to asthma: the atopic march. Ann Allergy Asthma Immunol 105:99\u2013106 (quiz 107\u2013109, 117)","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6 Suppl","key":"400_CR50","doi-asserted-by":"crossref","first-page":"S118","DOI":"10.1016\/j.jaci.2003.09.033","volume":"112","author":"JM Spergel","year":"2003","unstructured":"Spergel JM, Paller AS (2003) Atopic dermatitis and the atopic march. J Allergy Clin Immunol 112(6 Suppl):S118\u2013S127","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR51","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/sj.jid.5700487","volume":"127","author":"K Sugiura","year":"2007","unstructured":"Sugiura K, Muro Y, Nishizawa Y et al (2007) LEDGF\/DFS70, a major autoantigen of atopic dermatitis, is a component of keratohyalin granules. J Invest Dermatol 127:75\u201380","journal-title":"J Invest Dermatol"},{"key":"400_CR52","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1046\/j.1398-9995.2003.00367.x","volume":"59","author":"E Szakos","year":"2004","unstructured":"Szakos E, Lakos G, Aleksza M et al (2004) Association between the occurrence of the anticardiolipin IgM and mite allergen-specific IgE antibodies in children with extrinsic type of atopic eczema\/dermatitis syndrome. Allergy 59:164\u2013167","journal-title":"Allergy"},{"key":"400_CR53","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1159\/000246756","volume":"189","author":"J Tada","year":"1994","unstructured":"Tada J, Toi Y, Yoshioka T et al (1994) Antinuclear antibodies in patients with atopic dermatitis and severe facial lesions. Dermatology 189:38\u201340","journal-title":"Dermatology"},{"issue":"1209\u20131215","key":"400_CR54","first-page":"e2","volume":"129","author":"TS Tang","year":"2012","unstructured":"Tang TS, Bieber T, Williams HC (2012) Does \u201cautoreactivity\u201d play a role in atopic dermatitis? J Allergy Clin Immunol 129(1209\u20131215):e2","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR55","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/1523-1747.ep12329617","volume":"107","author":"R Valenta","year":"1996","unstructured":"Valenta R, Maurer D, Steiner R et al (1996) Immunoglobulin E response to human proteins in atopic patients. J Invest Dermatol 107:203\u2013208","journal-title":"J Invest Dermatol"},{"key":"400_CR56","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1067\/mai.2000.104783","volume":"105","author":"R Valenta","year":"2000","unstructured":"Valenta R, Seiberler S, Natter S et al (2000) Autoallergy: a pathogenetic factor in atopic dermatitis? J Allergy Clin Immunol 105:432\u2013437","journal-title":"J Allergy Clin Immunol"},{"key":"400_CR57","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1002\/art.20096","volume":"50","author":"A Watanabe","year":"2004","unstructured":"Watanabe A, Kodera M, Sugiura K et al (2004) Anti-DFS70 antibodies in 597 healthy hospital workers. Arthritis Rheum 50:892\u2013900","journal-title":"Arthritis Rheum"},{"key":"400_CR58","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3109\/08916934.2010.549157","volume":"44","author":"K Watanabe","year":"2011","unstructured":"Watanabe K, Muro Y, Sugiura K et al (2011) IgE and IgG(4) autoantibodies against DFS70\/LEDGF in atopic dermatitis. Autoimmunity 44:511\u2013519","journal-title":"Autoimmunity"},{"key":"400_CR59","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000108133","volume":"145","author":"S Zeller","year":"2008","unstructured":"Zeller S, Glaser AG, Vilhelmsson M et al (2008) Immunoglobulin-E-mediated reactivity to self antigens: a controversial issue. Int Arch Allergy Immunol 145:87\u201393","journal-title":"Int Arch Allergy Immunol"}],"container-title":["Archivum Immunologiae et Therapiae Experimentalis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00005-016-0400-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00005-016-0400-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00005-016-0400-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00005-016-0400-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T20:48:40Z","timestamp":1704228520000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00005-016-0400-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,4]]},"references-count":59,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["400"],"URL":"https:\/\/doi.org\/10.1007\/s00005-016-0400-3","relation":{},"ISSN":["0004-069X","1661-4917"],"issn-type":[{"type":"print","value":"0004-069X"},{"type":"electronic","value":"1661-4917"}],"subject":[],"published":{"date-parts":[[2016,5,4]]}}}