{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:22:08Z","timestamp":1740108128938,"version":"3.37.3"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T00:00:00Z","timestamp":1553212800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology","doi-asserted-by":"publisher","award":["BT\/PR12153\/INF\/22\/200\/2014"],"award-info":[{"award-number":["BT\/PR12153\/INF\/22\/200\/2014"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflamm. Res."],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1007\/s00011-019-01230-2","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T12:02:57Z","timestamp":1553256177000},"page":"347-349","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association of \u2212 757T\u2009>\u2009C polymorphism of C-reactive protein gene with chronic periodontitis of South Indian population"],"prefix":"10.1007","volume":"68","author":[{"given":"Sreekanth M.","family":"Selvaraj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith J.","family":"Christina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinthuja","family":"Gurumoorthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bagavad Gita","family":"Jayaraman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1740-1252","authenticated-orcid":false,"given":"Adaikkalam","family":"Vellaichamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,22]]},"reference":[{"key":"1230_CR1","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1111\/odi.12428","volume":"22","author":"LJ Jin","year":"2016","unstructured":"Jin LJ, Lamster IB, Greenspan JS, Pitts NB, Scully C, Warnakulasuriya S. Global burden of oral diseases: emerging concepts, management and interplay with systemic health. Oral Dis. 2016;22:609\u201319.","journal-title":"Oral Dis"},{"key":"1230_CR2","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1136\/postgradmedj-2017-134801","volume":"93","author":"AJ Gross","year":"2017","unstructured":"Gross AJ, Paskett KT, Cheever VJ, Lipsky MS. Periodontitis: a global disease and the primary care provider\u2019s role. Postgrad Med J. 2017;93:560\u20135.","journal-title":"Postgrad Med J"},{"key":"1230_CR3","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1111\/prd.12002","volume":"64","author":"A Cekici","year":"2014","unstructured":"Cekici A, Kantarci A, Hasturk H, Van Dyke TE. Inflammatory and immune pathways in the pathogenesis of periodontal disease. Periodontol 2000. 2014;64:57\u201380.","journal-title":"Periodontol 2000"},{"key":"1230_CR4","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1902\/jop.2005.76.11-S.2106","volume":"76","author":"BG Loos","year":"2005","unstructured":"Loos BG. Systemic markers of inflammation in periodontitis. J Periodontol. 2005;76:2106\u201315.","journal-title":"J Periodontol"},{"key":"1230_CR5","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1111\/j.1600-051X.2007.01173.x","volume":"35","author":"S Paraskevas","year":"2008","unstructured":"Paraskevas S, Huizinga JD, Loos BG. A systematic review and meta-analyses on C-reactive protein in relation to periodontitis. J Clin Periodontol. 2008;35:277\u201390.","journal-title":"J Clin Periodontol"},{"key":"1230_CR6","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1902\/jop.2010.090741","volume":"81","author":"Y Shimada","year":"2010","unstructured":"Shimada Y, Komatsu Y, Ikezawa-Suzuki I, Tai H, Sugita N, Yoshie H. The effect of periodontal treatment on serum leptin, interleukin-6, and C-reactive protein. J Periodontal. 2010;81:1118\u201323.","journal-title":"J Periodontal"},{"key":"1230_CR7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.20473\/j.djmkg.v48.i3.p113-118","volume":"48","author":"AW Suhartono","year":"2015","unstructured":"Suhartono AW, Sulijaya B, Djamal NZ, Masulili SL, Talbot C, Auerkari EI. Serum C-reactive protein and C-reactive gene (-717C> T) polymorphism are not associated with periodontitis in Indonesian male patients. Dental J. 2015;48:113\u20138.","journal-title":"Dental J"},{"key":"1230_CR8","volume-title":"Short protocols in molecular biology: a compendium of methods from current protocols in molecular biology","author":"FM Asubel","year":"2002","unstructured":"Asubel FM. Short protocols in molecular biology: a compendium of methods from current protocols in molecular biology. 5th ed. Amsterdam: Wiley; 2002.","edition":"5"},{"key":"1230_CR9","doi-asserted-by":"publisher","first-page":"e88-8","DOI":"10.1093\/nar\/29.17.e88","volume":"29","author":"S Ye","year":"2001","unstructured":"Ye S, Dhillon S, Ke X, Collins AR, Day IN. An efficient procedure for genotyping single nucleotide polymorphisms. Nucl Acids Res. 2001;29:e88-8.","journal-title":"Nucl Acids Res"},{"key":"1230_CR10","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1016\/j.humimm.2016.08.003","volume":"77","author":"MS Sreekanth","year":"2016","unstructured":"Sreekanth MS, Basha SE, Kumar GA, Govindaraju S, Nayar NP, Pitchappan RM. Association of IL-1\u03b2 + 3953 C and HLA-DRB1* 15 with coronary artery and rheumatic heart diseases in South India. Hum Immunol. 2016;77:1275\u201379.","journal-title":"Hum Immunol"},{"key":"1230_CR11","doi-asserted-by":"publisher","first-page":"254","DOI":"10.4103\/ijdr.IJDR_335_17","volume":"29","author":"SK Balaji","year":"2018","unstructured":"Balaji SK, Lavu V, Rao S. Chronic periodontitis prevalence and the inflammatory burden in a sample population from South India. Indian J Dent Res. 2018;29:254\u201359.","journal-title":"Indian J Dent Res"},{"key":"1230_CR12","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s12031-012-9856-8","volume":"49","author":"C Shen","year":"2013","unstructured":"Shen C, Sun X, Wang H, et al. Association study of CRP gene and ischemic stroke in a Chinese Han population. J Mol Neurosci. 2013;49:559\u201366.","journal-title":"J Mol Neurosci"},{"key":"1230_CR13","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/s12031-017-0945-6","volume":"62","author":"Y Xue","year":"2017","unstructured":"Xue Y, Zhang L, Fan Y, Li Q, Jiang Y, Shen C. C-reactive protein gene contributes to the genetic susceptibility of hemorrhagic stroke in men: a case\u2013control study in Chinese Han population. J Mol Neuroscience. 2017;62:395\u2013401.","journal-title":"J Mol Neuroscience"},{"key":"1230_CR14","doi-asserted-by":"publisher","first-page":"2752","DOI":"10.1152\/ajpheart.01164.2005","volume":"291","author":"Q Wang","year":"2006","unstructured":"Wang Q, Hunt SC, Xu Q, et al. Association study of CRP gene polymorphisms with serum CRP level and cardiovascular risk in the NHLBI Family Heart Study. Am J Physiol Heart Circ Physiol. 2006;291:2752\u20137.","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"1230_CR15","doi-asserted-by":"crossref","unstructured":"Sheu WHH, Wang WC, Wu KD, et al. CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: the SAPPHIRe study. Sci Rep 2017 7: 7987.","DOI":"10.1038\/s41598-017-08696-2"},{"key":"1230_CR16","doi-asserted-by":"publisher","first-page":"e24645","DOI":"10.1371\/journal.pone.0024645","volume":"6","author":"A Mahajan","year":"2011","unstructured":"Mahajan A, Tabassum R, Chavali S, et al. Common variants in CRP and LEPR influence high sensitivity C-reactive protein levels in North Indians. PLoS One. 2011;6:e24645.","journal-title":"PLoS One"}],"container-title":["Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00011-019-01230-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00011-019-01230-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00011-019-01230-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T19:50:34Z","timestamp":1694721034000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00011-019-01230-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,22]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["1230"],"URL":"https:\/\/doi.org\/10.1007\/s00011-019-01230-2","relation":{},"ISSN":["1023-3830","1420-908X"],"issn-type":[{"type":"print","value":"1023-3830"},{"type":"electronic","value":"1420-908X"}],"subject":[],"published":{"date-parts":[[2019,3,22]]},"assertion":[{"value":"4 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 March 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethical clearance for the study was obtained from the Institutional Ethical Committee of Sree Balaji Dental College and Hospital, Pallikaranai, Chennai, India\u2014600100 (Ethics Committee Registration No: ECR\/761\/Inst\/TN\/2015).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}