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This study was conducted in accordance with the declaration of Helsinki.\u00a0Informed consent was obtained from all individual participants included in the study. Registry and the Registration No. of the study\/trial: N\/A. Animal study was performed with the permission of the Animal Care and Use Committee of Sun Yat-Sen University (No. SYSU-IACUC-2023-000989).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"41"}}