{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T18:29:02Z","timestamp":1774031342178,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"7-8","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2007,4,2]],"date-time":"2007-04-02T00:00:00Z","timestamp":1175472000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell. Mol. Life Sci."],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1007\/s00018-007-6553-9","type":"journal-article","created":{"date-parts":[[2007,4,2]],"date-time":"2007-04-02T04:13:33Z","timestamp":1175487213000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Progesterone regulation of implantation-related genes: new insights into the role of oestrogen"],"prefix":"10.1007","volume":"64","author":[{"given":"H.","family":"Dassen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Punyadeera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Kamps","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Klomp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Dunselman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Dijcks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"de Goeij","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ederveen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Groothuis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,4,2]]},"reference":[{"key":"6553_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/humrep\/10.1.1","volume":"10","author":"D. Ghosh","year":"1995","unstructured":"Ghosh, D. and Sengupta, J. (1995) Another look at the issue of peri-implantation oestrogen. Hum. Reprod. 10, 1\u20132.","journal-title":"Hum. Reprod."},{"key":"6553_CR2","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1093\/molehr\/gag037","volume":"9","author":"A. Riesewijk","year":"2003","unstructured":"Riesewijk, A., Martin, J., van Os, R., Horcajadas, J. A., Polman, J., Pellicer, A., Mosselman, S. and Simon, C. (2003) Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology. Mol. Hum. Reprod. 9, 253\u2013264.","journal-title":"Mol. Hum. Reprod."},{"key":"6553_CR3","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1111\/j.1749-6632.2002.tb02786.x","volume":"955","author":"L. C. Giudice","year":"2002","unstructured":"Giudice, L. C., Telles, T. L., Lobo, S. and Kao, L. (2002) The molecular basis for implantation failure in endometriosis: on the road to discovery. Ann. NY Acad. Sci. 955, 252\u2013264; discussion 293\u20135, 396\u2013406.","journal-title":"Ann. NY Acad. Sci."},{"key":"6553_CR4","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1016\/j.steroids.2003.09.004","volume":"68","author":"B. A. Lessey","year":"2003","unstructured":"Lessey, B. A. (2003) Two pathways of progesterone action in the human endometrium: implications for implantation and contraception. Steroids 68, 809\u2013815.","journal-title":"Steroids"},{"key":"6553_CR5","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1016\/S0015-0282(99)00137-5","volume":"71","author":"O. H. Develioglu","year":"1999","unstructured":"Develioglu, O. H., Hsiu, J. G., Nikas, G., Toner, J. P., Oehninger, S. and Jones, H. W., Jr. (1999) Endometrial estrogen and progesterone receptor and pinopode expression in stimulated cycles of oocyte donors. Fertil. Steril. 71, 1040\u20131047.","journal-title":"Fertil. Steril."},{"key":"6553_CR6","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0165-0378(01)00140-1","volume":"55","author":"J. Martin","year":"2002","unstructured":"Martin, J., Dominguez, F., Avila, S. J., Castrillo, L., Remohi, J., Pellicer, A. and Simon, C. (2002) Human endometrial receptivity: gene regulation. J. Reprod. Immunol. 55, 131\u2013139.","journal-title":"J. Reprod. Immunol."},{"key":"6553_CR7","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1210\/jcem-68-4-801","volume":"68","author":"D. Navot","year":"1989","unstructured":"Navot, D., Anderson, T. L., Droesch, K., Scott, R. T., Kreiner, D. and Rosenwaks, Z. (1989) Hormonal manipulation of endometrial maturation. J. Clin. Endocrinol. Metab. 68, 801\u2013807.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"6553_CR8","doi-asserted-by":"publisher","first-page":"4809","DOI":"10.1210\/en.140.10.4809","volume":"140","author":"J. J. Brosens","year":"1999","unstructured":"Brosens, J. J., Hayashi, N. and White, J. O. (1999) Progesterone receptor regulates decidual prolactin expression in differentiating human endometrial stromal cells. Endocrinology 140, 4809\u20134820.","journal-title":"Endocrinology"},{"issue":"Suppl1","key":"6553_CR9","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/humrep\/15.suppl_1.74","volume":"15","author":"P. G. Satyaswaroop","year":"2000","unstructured":"Satyaswaroop, P. G. and Tabibzadeh, S. (2000) Progestin regulation of human endometrial function. Hum. Reprod. 15Suppl 1, 74\u201380.","journal-title":"Hum. Reprod."},{"key":"6553_CR10","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1023\/A:1009445913156","volume":"17","author":"H. Jung","year":"2000","unstructured":"Jung, H. and Roh, H. K. (2000) The effects of E2 supplementation from the early proliferative phase to the late secretory phase of the endometrium in hMG-stimulated IVF-ET. J. Assist. Reprod. Genet. 17, 28\u201333.","journal-title":"J. Assist. Reprod. Genet."},{"key":"6553_CR11","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1007\/BF01203817","volume":"9","author":"J. S. Younis","year":"1992","unstructured":"Younis, J. S., Mordel, N., Lewin, A., Simon, A., Schenker, J. G. and Laufer, N. (1992) Artificial endometrial preparation for oocyte donation: the effect of estrogen stimulation on clinical outcome. J. Assist. Reprod. Genet. 9, 222\u2013227.","journal-title":"J. Assist. Reprod. Genet."},{"key":"6553_CR12","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s00018-004-4435-y","volume":"62","author":"C. Punyadeera","year":"2005","unstructured":"Punyadeera, C., Dassen, H., Klomp, J., Dunselman, G., Kamps, R., Dijcks, F., Ederveen, A., de Goeij, A. and Groothuis, P. (2005) Oestrogen-modulated gene expression in the human endometrium. Cell. Mol. Life Sci. 62, 239\u2013250.","journal-title":"Cell. Mol. Life Sci."},{"key":"6553_CR13","doi-asserted-by":"publisher","first-page":"11789","DOI":"10.1073\/pnas.89.24.11789","volume":"89","author":"E. Marbaix","year":"1992","unstructured":"Marbaix, E., Donnez, J., Courtoy, P. J. and Eeckhout, Y. (1992) Progesterone regulates the activity of collagenase and related gelatinases A and B in human endometrial explants. Proc. Natl. Acad. Sci. USA 89, 11789\u201311793.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"6553_CR14","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/0022-4731(90)90196-Y","volume":"35","author":"L. Markiewicz","year":"1990","unstructured":"Markiewicz, L. and Gurpide, E. (1990) In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD-14) and its metabolites on human endometrium. J. Steroid Biochem. 35, 535\u2013541.","journal-title":"J. Steroid Biochem."},{"key":"6553_CR15","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0002-9378(16)33500-1","volume":"122","author":"R. W. Noyes","year":"1975","unstructured":"Noyes, R. W., Hertig, A. T. and Rock, J. (1975) Dating the endometrial biopsy. Am. J. Obstet. Gynecol. 122, 262\u2013263.","journal-title":"Am. J. Obstet. Gynecol."},{"key":"6553_CR16","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.jsbmb.2004.06.005","volume":"92","author":"C. Punyadeera","year":"2004","unstructured":"Punyadeera, C., Dunselman, G., Marbaix, E., Kamps, R., Galant, C., Nap, A., Goeij, A., Ederveen, A. and Groothuis, P. (2004) Triphasic pattern in the ex vivo response of human proliferative phase endometrium to oestrogens. J. Steroid Biochem. Mol. Biol. 92, 175\u2013185.","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"6553_CR17","doi-asserted-by":"publisher","first-page":"42496","DOI":"10.1074\/jbc.M201793200","volume":"277","author":"P. B. Cornet","year":"2002","unstructured":"Cornet, P. B., Picquet, C., Lemoine, P., Osteen, K. G., Bruner-Tran, K. L., Tabibzadeh, S., Courtoy, P. J., Eeckhout, Y., Marbaix, E. and Henriet, P. (2002) Regulation and function of LEFTY-A\/EBAF in the human endometrium. mRNA expression during the menstrual cycle, control by progesterone, and effect on matrix metalloprotineases. J. Biol. Chem. 277, 42496\u201342504.","journal-title":"J. Biol. Chem."},{"key":"6553_CR18","unstructured":"Weng, L. (2003) Data Processing and Analysis Methods in the Rosetta Resolver. 38. Technical report."},{"key":"6553_CR19","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"K. J. Livak","year":"2001","unstructured":"Livak, K. J. and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402\u2013408.","journal-title":"Methods"},{"key":"6553_CR20","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1093\/molehr\/8.9.871","volume":"8","author":"D. D. Carson","year":"2002","unstructured":"Carson, D. D., Lagow, E., Thathiah, A., Al-Shami, R., Farach-Carson, M. C., Vernon, M., Yuan, L., Fritz, M. A. and Lessey, B. (2002) Changes in gene expression during the early to midluteal (receptive phase) transition in human endometrium detected by high-density microarray screening. Mol. Hum. Reprod. 8, 871\u2013879.","journal-title":"Mol. Hum. Reprod."},{"key":"6553_CR21","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1210\/en.143.6.2119","volume":"143","author":"L. C. Kao","year":"2002","unstructured":"Kao, L. C., Tulac, S., Lobo, S., Imani, B., Yang, J. P., Germeyer, A., Osteen, K., Taylor, R. N., Lessey, B. A. and Giudice, L. C. (2002) Global gene profiling in human endometrium during the window of implantation. Endocrinology 143, 2119\u20132138.","journal-title":"Endocrinology"},{"key":"6553_CR22","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/j.1749-6632.1991.tb37864.x","volume":"622","author":"D. Navot","year":"1991","unstructured":"Navot, D. and Bergh, P. (1991) Preparation of the human endometrium for implantation. Ann. NY Acad. Sci. 622, 212\u2013219.","journal-title":"Ann. NY Acad. Sci."},{"key":"6553_CR23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1095\/biolreprod47.3.441","volume":"47","author":"L. Tseng","year":"1992","unstructured":"Tseng, L., Gao, J. G., Chen, R., Zhu, H. H., Mazella, J. and Powell, D. R. (1992) Effect of progestin, antiprogestin, and relaxin on the accumulation of prolactin and insulin-like growth factor-binding protein-1 messenger ribonucleic acid in human endometrial stromal cells. Biol. Reprod. 47, 441\u2013450.","journal-title":"Biol. Reprod."},{"issue":"Suppl","key":"6553_CR24","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1038\/ng1034","volume":"32","author":"R. F. Chuaqui","year":"2002","unstructured":"Chuaqui, R. F., Bonner, R. F., Best, C. J., Gillespie, J.W., Flaig, M. J., Hewitt, S. M., Phillips, J. L., Krizman, D. B., Tangrea, M. A., Ahram, M., Linehan, W. M., Knezevic, V. and Emmert-Buck, M. R. (2002) Post-analysis follow-up and validation of microarray experiments. Nat. Genet. 32Suppl, 509\u2013514.","journal-title":"Nat. Genet."},{"key":"6553_CR25","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.ygeno.2003.09.017","volume":"83","author":"J. C. Rockett","year":"2004","unstructured":"Rockett, J. C. and Hellmann, G. M. (2004) Confirming microarray data\u2014is it really necessary? Genomics 83, 541\u2013549.","journal-title":"Genomics"},{"key":"6553_CR26","first-page":"42","volume":"32","author":"N. Goodman","year":"2003","unstructured":"Goodman, N. (2003) Microarrays: hazardous to your science. Genome Technol. 32, 42\u201345.","journal-title":"Genome Technol."},{"key":"6553_CR27","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1093\/humrep\/deh507","volume":"19","author":"X. Y. Zheng","year":"2004","unstructured":"Zheng, X. Y., Chen, G. A. and Wang, H. Y. (2004) Expression of cystic fibrosis transmembrane conductance regulator in human endometrium. Hum. Reprod. 19, 2933\u20132941.","journal-title":"Hum. Reprod."},{"key":"6553_CR28","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1002\/aja.1000920202","volume":"92","author":"J.G. Wilson","year":"1953","unstructured":"Wilson, J.G., Roth, C. B. and Warkany, J. (1953) An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am. J. Anat. 92, 189\u2013217.","journal-title":"Am. J. Anat."},{"key":"6553_CR29","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1002\/(SICI)1099-0844(1998120)16:4<227::AID-CBF787>3.0.CO;2-M","volume":"16","author":"M. Simsek","year":"1998","unstructured":"Simsek, M., Naziroglu, M., Simsek, H., Cay, M., Aksakal, M. and Kumru, S. (1998) Blood plasma levels of lipoperoxides, glutathione peroxidase, beta carotene, vitamin A and E in women with habitual abortion. Cell Biochem. Funct. 16, 227\u2013231.","journal-title":"Cell Biochem. Funct."},{"key":"6553_CR30","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1093\/jn\/104.11.1513","volume":"104","author":"B. A. O\u2019Toole","year":"1974","unstructured":"O\u2019Toole, B. A., Fradkin, R., Warkany, J., Wilson, J. G. and Mann, G. V. (1974) Vitamin A deficiency and reproduction in rhesus monkeys. J. Nutr. 104, 1513\u20131524.","journal-title":"J. Nutr."},{"key":"6553_CR31","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1093\/humrep\/deg018","volume":"18","author":"F. J. Huang","year":"2003","unstructured":"Huang, F. J., Shen, C. C., Chang, S. Y., Wu, T. C. and Hsuuw, Y. D. (2003) Retinoic acid decreases the viability of mouse blastocysts in vitro. Hum. Reprod. 18, 130\u2013136.","journal-title":"Hum. Reprod."},{"key":"6553_CR32","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/molehr\/2.3.185","volume":"2","author":"A. K. Brar","year":"1996","unstructured":"Brar, A. K., Kessler, C. A., Meyer, A. J., Cedars, M. I. and Jikihara, H. (1996) Retinoic acid suppresses in-vitro decidualization of human endometrial stromal cells. Mol. Hum. Reprod. 2, 185\u2013193.","journal-title":"Mol. Hum. Reprod."},{"key":"6553_CR33","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1093\/ajcn\/32.7.1433","volume":"32","author":"A. Vahlquist","year":"1979","unstructured":"Vahlquist, A., Johnsson, A. and Nygren, K. G. (1979) Vitamin A transporting plasma proteins and female sex hormones. Am. J. Clin. Nutr. 32, 1433\u20131438.","journal-title":"Am. J. Clin. Nutr."},{"key":"6553_CR34","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1093\/ajcn\/28.7.686","volume":"28","author":"D. L. Yeung","year":"1975","unstructured":"Yeung, D. L. and Chan, P. L. (1975) Effects of a progestogen and a sequential type oral contraceptive on plasma vitamin A, vitamin E, cholesterol and triglycerides. Am. J. Clin. Nutr. 28, 686\u2013691.","journal-title":"Am. J. Clin. Nutr."},{"key":"6553_CR35","doi-asserted-by":"publisher","first-page":"2157","DOI":"10.1210\/jc.2002-021844","volume":"88","author":"L. Deng","year":"2003","unstructured":"Deng, L., Shipley, G. L., Loose-Mitchell, D. S., Stancel, G. M., Broaddus, R., Pickar, J. H. and Davies, P. J. (2003) Coordinate regulation of the production and signaling of retinoic acid by estrogen in the human endometrium. J. Clin. Endocrinol. Metab. 88, 2157\u20132163.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"6553_CR36","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/B978-0-12-658101-0.50012-3","volume-title":"The Retinoids","author":"B. A. Underwood","year":"1984","unstructured":"Underwood, B. A. (1984) Vitamin A in animal and human nutrition. In: The Retinoids, pp. 281\u2013392, Sporn, M. B., Roberts, A. B., Goodman, D. S. (eds.) Academic Press, London."},{"key":"6553_CR37","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/j.steroids.2003.07.001","volume":"68","author":"H. O. Critchley","year":"2003","unstructured":"Critchley, H. O., Kelly, R.W., Brenner, R. M. and Baird, D. T. (2003) Antiprogestins as a model for progesterone withdrawal. Steroids 68, 1061\u20131068.","journal-title":"Steroids"},{"key":"6553_CR38","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/j.8755-8920.2000.430405.x","volume":"43","author":"L. Flynn","year":"2000","unstructured":"Flynn, L., Byrne, B., Carton, J., Kelehan, P., O\u2019Herlihy, C. and O\u2019Farrelly, C. (2000) Menstrual cycle dependent fluctuations in NK and T-lymphocyte subsets from non-pregnant human endometrium. Am. J. Reprod. Immunol. 43, 209\u2013217.","journal-title":"Am. J. Reprod. Immunol."},{"key":"6553_CR39","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1210\/endo-129-5-2385","volume":"129","author":"J. C. Irwin","year":"1991","unstructured":"Irwin, J. C., Utian, W. H. and Eckert, R. L. (1991) Sex steroids and growth factors differentially regulate the growth and differentiation of cultured human endometrial stromal cells. Endocrinology 129, 2385\u20132392.","journal-title":"Endocrinology"},{"key":"6553_CR40","doi-asserted-by":"publisher","first-page":"3978","DOI":"10.1073\/pnas.86.11.3978","volume":"86","author":"R. Z. Florkiewicz","year":"1989","unstructured":"Florkiewicz, R. Z. and Sommer, A. (1989) Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons. Proc. Natl. Acad. Sci. USA 86, 3978\u20133981.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"6553_CR41","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/molehr\/7.1.65","volume":"7","author":"B. Moller","year":"2001","unstructured":"Moller, B., Rasmussen, C., Lindblom, B. and Olovsson, M. (2001) Expression of the angiogenic growth factors VEGF, FGF-2, EGF and their receptors in normal human endometrium during the menstrual cycle. Mol. Hum. Reprod. 7, 65\u201372.","journal-title":"Mol. Hum. Reprod."},{"key":"6553_CR42","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1074\/jbc.273.1.544","volume":"273","author":"R. Z. Florkiewicz","year":"1998","unstructured":"Florkiewicz, R. Z., Anchin, J. and Baird, A. (1998) The inhibition of fibroblast growth factor-2 export by cardenolides implies a novel function for the catalytic subunit of Na+,K+-ATPase. J. Biol. Chem. 273, 544\u2013551.","journal-title":"J. Biol. Chem."},{"key":"6553_CR43","first-page":"389","volume":"77","author":"R. K. Sangha","year":"1997","unstructured":"Sangha, R. K., Li, X. F., Shams, M. and Ahmed, A. (1997) Fibroblast growth factor receptor-1 is a critical component for endometrial remodeling: localization and expression of basic fibroblast growth factor and FGF-R1 in human endometrium during the menstrual cycle and decreased FGF-R1 expression in menorrhagia. Lab. Invest. 77, 389\u2013402.","journal-title":"Lab. Invest."},{"key":"6553_CR44","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/0955-2235(95)00041-0","volume":"6","author":"M. Allouche","year":"1995","unstructured":"Allouche, M. and Bikfalvi, A. (1995) The role of fibroblast growth factor-2 (FGF-2) in hematopoiesis. Prog. Growth Factor Res. 6, 35\u201348.","journal-title":"Prog. Growth Factor Res."},{"key":"6553_CR45","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1001\/jama.292.1.81","volume":"292","author":"H. S. Taylor","year":"2004","unstructured":"Taylor, H. S. (2004) Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA 292, 81\u201385.","journal-title":"JAMA"}],"container-title":["Cellular and Molecular Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-007-6553-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00018-007-6553-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-007-6553-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-007-6553-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T17:29:53Z","timestamp":1630430993000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00018-007-6553-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":45,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["6553"],"URL":"https:\/\/doi.org\/10.1007\/s00018-007-6553-9","relation":{},"ISSN":["1420-682X","1420-9071"],"issn-type":[{"value":"1420-682X","type":"print"},{"value":"1420-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4]]},"assertion":[{"value":"2 April 2007","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"1009"}}