{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T23:58:51Z","timestamp":1768867131953,"version":"3.49.0"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2015,1,17]],"date-time":"2015-01-17T00:00:00Z","timestamp":1421452800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell. Mol. Life Sci."],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1007\/s00018-014-1825-7","type":"journal-article","created":{"date-parts":[[2015,1,16]],"date-time":"2015-01-16T02:51:21Z","timestamp":1421376681000},"page":"885-896","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Spectroscopic and computational characterization of laccases and their substrate radical intermediates"],"prefix":"10.1007","volume":"72","author":[{"given":"Rebecca","family":"Pogni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Camilla","family":"Baratto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adalgisa","family":"Sinicropi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Basosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,1,17]]},"reference":[{"key":"1825_CR1","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1039\/CT8834300472","volume":"43","author":"H Yoshida","year":"1883","unstructured":"Yoshida H (1883) Chemistry of lacquer (urushi). Part I. J Chem Soc 43:472\u2013486","journal-title":"J Chem Soc"},{"key":"1825_CR2","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0031-9422(02)00171-1","volume":"60","author":"AM Mayer","year":"2002","unstructured":"Mayer AM, Staples RC (2002) Laccase: new Functions for an old enzyme. Phytochemistry 60:551\u2013565","journal-title":"Phytochemistry"},{"key":"1825_CR3","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.molcatb.2011.01.016","volume":"69","author":"G Shumacovich","year":"2009","unstructured":"Shumacovich G, Streltsov A, Gorshina E, Rusinova T, Kurova V, Vasil\u2019eva I, Otrokhov G, Morozova O, Yaropolov A (2009) Laccase-catalyzed oxidative polymerization of aniline dimer (N-phenyl-1,4-phenylendiamine) in aqueous micellar solution of sodium dodecylbenzenesulfonate. J Mol Cat B Enzym 69:83\u201388","journal-title":"J Mol Cat B Enzym"},{"key":"1825_CR4","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/BF02783061","volume":"49","author":"AI Yaropolov","year":"1994","unstructured":"Yaropolov AI, Skorobogat\u2019ko OV, Vartanov SS, Varfolomeev SD (1994) Laccase: properties, catalytic mechanism and applicability. Appl Biochem Biotechnol 49:257\u2013280","journal-title":"Appl Biochem Biotechnol"},{"key":"1825_CR5","doi-asserted-by":"crossref","first-page":"7608","DOI":"10.1021\/bi952971a","volume":"35","author":"F Xu","year":"1996","unstructured":"Xu F (1996) Oxidation of phenols, anilines, and benzenethiols by fungal laccases: correlation between activity and redox potentials as well as halide inhibition. Biochemistry 35:7608\u20137614","journal-title":"Biochemistry"},{"key":"1825_CR6","doi-asserted-by":"crossref","unstructured":"Messerschmidt A (ed) (1997) Multi-copper oxidases. World Scientific Singapore, Singapore","DOI":"10.1142\/3146"},{"key":"1825_CR7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10889869991219163","volume":"3","author":"L Gianfreda","year":"1999","unstructured":"Gianfreda L, Xu F, Bollag JM (1999) Laccases: a useful group of oxidoreductive enzymes. Bioremediat J 3:1\u201326","journal-title":"Bioremediat J"},{"key":"1825_CR8","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0304-4173(85)90014-X","volume":"811","author":"RA Marcus","year":"1985","unstructured":"Marcus RA, Sutin N (1985) Electron transfer in chemistry and biology. Biochim Biophys Acta 811:265\u2013322","journal-title":"Biochim Biophys Acta"},{"key":"1825_CR9","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1128\/AEM.66.5.2052-2056.2000","volume":"66","author":"F Xu","year":"2000","unstructured":"Xu F, Kulys JJ, Duke K, Li K, Krikstopaitis K, Deusse HJW, Abbate E, Galinyte V, Schneider P (2000) Redox chemistry in laccase-catalyzed oxidation of N-Hydroxy compounds. Appl Environ Microbiol 66:2052\u20132056","journal-title":"Appl Environ Microbiol"},{"key":"1825_CR10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0167-4838(95)00210-3","volume":"1292","author":"F Xu","year":"1996","unstructured":"Xu F, Shin W, Brown SH, Wahleithner JA, Sundaram UM, Solomon EI (1996) A study of a series of recombinant fungal laccases and bilirubin oxidase that exhibit significant differences in redox potential, substrate specificity and stability. Biochim Biophys Acta 1292:303\u2013311","journal-title":"Biochim Biophys Acta"},{"key":"1825_CR11","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00253-009-1869-z","volume":"82","author":"A Mikolasch","year":"2009","unstructured":"Mikolasch A, Schauer F (2009) Fungal laccases as tools for the synthesis of new hybrid molecules and biomaterials. Appl Microbiol Biotechnol 82:605\u2013624","journal-title":"Appl Microbiol Biotechnol"},{"key":"1825_CR12","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1574-4976.2005.00010.x","volume":"30","author":"P Baldrian","year":"2006","unstructured":"Baldrian P (2006) Fungal laccases\u2014occurrence and properties. FEMS Microbial rev 30:215\u2013224","journal-title":"FEMS Microbial rev"},{"key":"1825_CR13","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.crvi.2011.06.007","volume":"334","author":"A Piscitelli","year":"2011","unstructured":"Piscitelli A, Del Vecchio C, Faraco V, Giardina P, Macellaro G, Miele A, Pezzella C, Sannia G (2011) Fungal laccases: versatile tools for lignocellulose transformation. C R Biol 334:789\u2013794","journal-title":"C R Biol"},{"key":"1825_CR14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0014-5793(90)80298-W","volume":"267","author":"R Bourbonnais","year":"1990","unstructured":"Bourbonnais R, Paice MG (1990) Oxidation of non-phenolic substrates. An expanded role for laccase in lignin biodegradation. FEBS 267:99\u2013102","journal-title":"FEBS"},{"key":"1825_CR15","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.procbio.2012.05.006","volume":"47","author":"J Polak","year":"2012","unstructured":"Polak J, Jarosz-Wilkolazka A (2012) Fungal Laccases as green catalysts for dye synthesis. Process Biochem 47:1295\u20131307","journal-title":"Process Biochem"},{"key":"1825_CR16","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.molcatb.2009.12.018","volume":"63","author":"S Forte","year":"2010","unstructured":"Forte S, Polak J, Valensin D, Taddei M, Basosi R, Vanhulle S, Jarosz-Wilkolazka A, Pogni R (2010) Synthesis and structural characterization of a novel phenoxazinone dye by use of a fungal laccase. J Mol Catal B Enzym 63:116\u2013120","journal-title":"J Mol Catal B Enzym"},{"key":"1825_CR17","unstructured":"Bruyneel F, Basosi R, Bols CM, Enaud E, Hercher C, Jager IJ, Marchand-Brynaert J, Pogni R, Polak J, Jarosz A, Wilkolaska A, Vanhulle S, Phenoxazine dyes. US Patent 61\/078670 (2008) and 12\/498,666 (2009) and PCT PCT\/EP2009\/058640 (2009)"},{"key":"1825_CR18","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1021\/cr100334x","volume":"111","author":"D Monti","year":"2011","unstructured":"Monti D, Ottolina G, Carrea G, Riva S (2011) Redox Chemistry catalyzed by isolated enzymes. Chem Rev 111:4111\u20134140","journal-title":"Chem Rev"},{"key":"1825_CR19","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s12010-008-8279-z","volume":"157","author":"DMS Wong","year":"2009","unstructured":"Wong DMS (2009) Structure and action mechanism of ligninolytic enzymes. Appl Biochem Biotechnol 157:174\u2013209","journal-title":"Appl Biochem Biotechnol"},{"key":"1825_CR20","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00775-009-0590-9","volume":"15","author":"DJJ Kosman","year":"2010","unstructured":"Kosman DJJ (2010) Multicopper oxidases: a workshop on copper coordination chemistry, electron transfer, and metallophysiology. J Biol Inorg Chem 15:15\u201328","journal-title":"J Biol Inorg Chem"},{"key":"1825_CR21","first-page":"1","volume-title":"Copper proteins and copper enzymes","author":"B Reinhammar","year":"1984","unstructured":"Reinhammar B (1984) In: Lontie R (ed) Copper proteins and copper enzymes. CRC Press, Boca Raton, p 1"},{"key":"1825_CR22","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1021\/cr950046o","volume":"96","author":"EI Solomon","year":"1996","unstructured":"Solomon EI, Sundaram UM, Machonkin TE (1996) Multicopper oxidases and oxygenases. Chem Rev 96:2563\u20132606","journal-title":"Chem Rev"},{"key":"1825_CR23","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1021\/cr00012a003","volume":"92","author":"EI Solomon","year":"1992","unstructured":"Solomon EI, Baldwin MJ, Lowery MD (1992) Electronic structures of active sites in copper proteins: contributions to reactivity. Chem Rev 92:521\u2013542","journal-title":"Chem Rev"},{"key":"1825_CR24","doi-asserted-by":"crossref","first-page":"37663","DOI":"10.1074\/jbc.M204571200","volume":"277","author":"K Piontek","year":"2002","unstructured":"Piontek K, Antorini M, Choinowski T (2002) Crystal structure of a laccase from the fungus Trametes versicolor at 1.90-\u00c5 resolution containing a full complement of coppers. J Biol Chem 277:37663\u201337669","journal-title":"J Biol Chem"},{"key":"1825_CR25","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/07391102.2012.674275","volume":"30","author":"MT Cambria","year":"2012","unstructured":"Cambria MT, Gullotto D, Garavaglia S, Cambria A (2012) In silico study of structural determinants modulating the redox potential of Rigidoporus lignosus and other fungal laccases. J Biomol Struct Dyn 30:89\u2013101","journal-title":"J Biomol Struct Dyn"},{"key":"1825_CR26","doi-asserted-by":"crossref","first-page":"13609","DOI":"10.1073\/pnas.0705137104","volume":"104","author":"J Yoon","year":"2007","unstructured":"Yoon J, Liboiron BD, Sarangi R, Hodgson KO, Hedman B, Solomon EI (2007) The two oxidized forms of the trinuclear Cu cluster in the multicopper oxidases and mechanism for the decay of the native intermediate. Proc Natl Acad Sci USA 104:13609\u201313614","journal-title":"Proc Natl Acad Sci USA"},{"key":"1825_CR27","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1021\/ja062954g","volume":"129","author":"U Ryde","year":"2007","unstructured":"Ryde U, Hsiao Y-W, Rul\u00ed\u0161ek L, Solomon EI (2007) Identification of the peroxy adduct in multicopper oxidases by a combination of computational chemistry and extended x-ray absorption fine-structure measurements. J Am Chem Soc 129:726\u2013727","journal-title":"J Am Chem Soc"},{"key":"1825_CR28","doi-asserted-by":"crossref","first-page":"4949","DOI":"10.1007\/s00253-013-5491-8","volume":"98","author":"G Macellaro","year":"2014","unstructured":"Macellaro G, Baratto MC, Piscitelli A, Pezzella C, Fabrizi de Biani F, Palmese A, Piumi F, Record E, Basosi R, Sannia G (2014) Effective mutations in a high redox potential laccase from Pleurotus ostreatus. Appl Microbiol Biotechnol 98:4949\u20134961","journal-title":"Appl Microbiol Biotechnol"},{"key":"1825_CR29","first-page":"411","volume-title":"Biological applications of electron spin resonance","author":"T V\u00e4nng\u00e5rd","year":"1972","unstructured":"V\u00e4nng\u00e5rd T (1972) In: Bolton JR, Swartz HM, Borg DC (eds) Biological applications of electron spin resonance. Wiley, New York, p 411"},{"key":"1825_CR30","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1146\/annurev.bb.11.060182.002135","volume":"11","author":"JS Hyde","year":"1982","unstructured":"Hyde JS, Froncisz W (1982) Ann Rev Biophys Bioeng 11:391","journal-title":"Ann Rev Biophys Bioeng"},{"key":"1825_CR31","unstructured":"Basosi R, Antholine WE, Hyde JS (2004) Multifrequency ESR of copper: biophysical applications. In: Berliner LJ, Reuben J (eds) Biological magnetic resonance. Plenum Press, New York, pp 103\u2013150"},{"key":"1825_CR32","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/10242420701422757","volume":"25","author":"R Pogni","year":"2007","unstructured":"Pogni R, Brogioni B, Baratto MC, Sinicropi A, Giardina P, Pezzella C, Sannia G, Basosi R (2007) Evidence for a radical mechanism in biocatalytic degradation of synthetic dyes by fungal laccases mediated by violuric acid. Biocatal Biotransform 25:269\u2013275","journal-title":"Biocatal Biotransform"},{"key":"1825_CR33","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.molcatb.2014.05.023","volume":"107","author":"A Martorana","year":"2014","unstructured":"Martorana A, Vazquez-Duhalt R, Auila SA, Basosi R, Baratto MC (2014) Spectroscopic characterization of 2,6-dimethoxyphenol radical intermediates in the Coriolopsis gallica laccase-mediator system. J Mol Catal B Enzym 107:100\u2013105","journal-title":"J Mol Catal B Enzym"},{"key":"1825_CR34","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1063\/1.440548","volume":"73","author":"W Froncisz","year":"1980","unstructured":"Froncisz W, Hyde JS (1980) Broadening by strains of lines in the g-parallel region of Cu2+ EPR spectra. J Chem Phys 73:3123\u20133131","journal-title":"J Chem Phys"},{"key":"1825_CR35","unstructured":"Basosi R, Della Lunga G, Pogni R (2004) Copper biomolecules in solution. In: Eaton SS, Eaton GR, Berliner LJ (eds)\u00a0Biomedical EPR-part A: free radicals, metals, medicine and physiology. Kluwer Academic\/Plenum Publishers, New York, pp 385\u2013416"},{"key":"1825_CR36","unstructured":"Antholine WE (2004) Low frequency EPR of Cu2+. In: Eaton SS, Eaton GR, Berliner LJ (eds)\u00a0Biomedical EPR-part A: free radicals, metals, medicine and physiology. Kluwer Academic\/Plenum Publishers, New York, pp 417\u2013454"},{"key":"1825_CR37","first-page":"564","volume":"D68","author":"E Mora De la","year":"2012","unstructured":"De la Mora E, Lovett JE, Blanford CF, Garman EF, Valderrama B, Rudino-Pinera E (2012) Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase. Acta Cryst D68:564\u2013577","journal-title":"Acta Cryst"},{"key":"1825_CR38","doi-asserted-by":"crossref","first-page":"3176","DOI":"10.1111\/j.1742-4658.2010.07725.x","volume":"277","author":"AT Fernandes","year":"2010","unstructured":"Fernandes AT, Damas JM, Todorovic S, Huber R, Baratto MC, Pogni R, Soares CM, Martins LO (2010) The multicopper oxidase from the archaeon Pyrobaculum aerophilum shows nitrous oxide reductase activity. FEBS J 277:3176\u20133189","journal-title":"FEBS J"},{"key":"1825_CR39","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1039\/B208951C","volume":"1","author":"P Baiocco","year":"2003","unstructured":"Baiocco P, Barreca AM, Fabbrini M, Galli C, Gentili P (2003) Promoting laccase activity towards non-phenolic substrates: a mechanistic investigation with some laccase-mediator systems. Org Biomol Chem 1:191\u2013197","journal-title":"Org Biomol Chem"},{"key":"1825_CR40","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S1381-1177(02)00082-6","volume":"18","author":"M Fabbrini","year":"2002","unstructured":"Fabbrini M, Galli C, Gentili P (2002) Radical or electron-transfer mechanism of oxidation with some laccase\/mediator systems. J Mol Cat B Enzym 18:169\u2013171","journal-title":"J Mol Cat B Enzym"},{"key":"1825_CR41","doi-asserted-by":"crossref","first-page":"6703","DOI":"10.1021\/es8008979","volume":"42","author":"S Camarero","year":"2008","unstructured":"Camarero S, Canas AI, Nousiainen P, Record E, Lomascolo A, Martinez MJ, Martinez AT (2008) p-Hydroxycinnamic acids as natural mediators for laccase oxidation of recalcitrant compounds. Environ Sci Technol 42:6703\u20136709","journal-title":"Environ Sci Technol"},{"key":"1825_CR42","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.chemosphere.2009.07.039","volume":"77","author":"C Torres Duarte","year":"2009","unstructured":"Torres Duarte C, Roman R, Tinoco R, Vazquez-Duhalt R (2009) Halogenated pesticide transformation by a laccase-mediator system. Chemosphere 77:687\u2013692","journal-title":"Chemosphere"},{"key":"1825_CR43","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0141-0229(97)00199-3","volume":"22","author":"A Majcherczyk","year":"1998","unstructured":"Majcherczyk A, Johannes C, H\u00fcttermann A (1998) Oxidation of polycyclic aromatic hydrocarbons (PAH) by laccase of Trametes versicolor. Enzyme Microbial Technol 22:335\u2013341","journal-title":"Enzyme Microbial Technol"},{"key":"1825_CR44","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1128\/AEM.66.2.524-528.2000","volume":"66","author":"C Johannes","year":"2000","unstructured":"Johannes C, Majcherczyk A (2000) Natural mediators in the oxidation of polycyclic aromatic hydrocarbons by laccase mediator systems. Appl Environ Microbiol 66:524\u2013528","journal-title":"Appl Environ Microbiol"},{"key":"1825_CR45","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1128\/AEM.71.4.1775-1784.2005","volume":"71","author":"S Camarero","year":"2005","unstructured":"Camarero S, Ibarra D, Martinez MJ, Martinez AT (2005) Lignin-derived compounds as efficient laccase mediators for decolorization of different types of recalcitrant dyes. Appl Environ Microbiol 71:1775\u20131784","journal-title":"Appl Environ Microbiol"},{"key":"1825_CR46","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1134\/S0003683807050055","volume":"43","author":"OV Morozova","year":"2007","unstructured":"Morozova OV, Shumakovich GP, Shleev SV, Yaropolov YI (2007) Laccase-mediator systems and their applications: a review. Appl Biochem Microbiol 43:523\u2013535","journal-title":"Appl Biochem Microbiol"},{"key":"1825_CR47","doi-asserted-by":"crossref","first-page":"7284","DOI":"10.1039\/b812096j","volume":"10","author":"B Brogioni","year":"2008","unstructured":"Brogioni B, Biglino D, Sinicropi A, Reijerse EJ, Giardina P, Sannia G, Lubitz W, Basosi R, Pogni R (2008) Characterization of radical intermediates in laccase-mediator systems. A multifrequency EPR, ENDOR and DFT\/PCM investigation. Phys Chem Chem Phys 10:7284\u20137292","journal-title":"Phys Chem Chem Phys"},{"key":"1825_CR48","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1039\/c1mb05301a","volume":"7","author":"A Martorana","year":"2011","unstructured":"Martorana A, Bernini C, Valensin D, Sinicropi A, Pogni R, Basosi R (2011) Baratto MC (2011) Insights into the homocoupling reaction of 4-methylamino benzoic acid mediated by Trametes versicolor laccase. Mol Biosyst 7:2967\u20132969","journal-title":"Mol Biosyst"},{"key":"1825_CR49","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1246\/bcsj.57.673","volume":"57","author":"J Lopez","year":"1984","unstructured":"Lopez J, Yamauchi J, Okada K, Deguchi Y (1984) ENDOR study of benzothiazolone azine cation radicals by means of a TM110 Mode Cavity. Bull Chem Soc Jpn 57:673\u2013677","journal-title":"Bull Chem Soc Jpn"},{"key":"1825_CR50","doi-asserted-by":"crossref","unstructured":"Scott SL, Chen WJ, Bakac A, Espenson JH (1993) Spectroscopic parameters electrode potentials, acid ionization constants, and electron exchange rates of the 2,2\u2032-azinobis(3-ethylbenzothiazolone-6-sulfonate) radicals and ions. J Phys Chem 97:6710\u20136714","DOI":"10.1021\/j100127a022"},{"key":"1825_CR51","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0009-2614(03)00305-1","volume":"371","author":"HC Kim","year":"2003","unstructured":"Kim HC, Mickel M, Hampp N (2003) Molecular origin of the stability of violuric acid radicals at high pH-values. Chem Phys Lett 371:410\u2013416","journal-title":"Chem Phys Lett"},{"key":"1825_CR52","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1023\/A:1008193805436","volume":"14","author":"G Schaftenaar","year":"2000","unstructured":"Schaftenaar G, Noordik JH (2000) Molden: a pre- and post-processing program for molecular and electronic structures. J Comput Aided Mol Des 14:123\u2013134","journal-title":"J Comput Aided Mol Des"},{"key":"1825_CR53","doi-asserted-by":"crossref","first-page":"23472","DOI":"10.1074\/jbc.M314000200","volume":"279","author":"FJ Enguita","year":"2004","unstructured":"Enguita FJ, Marcal D, Martins LO, Grenha R, Henriques AO, Lindley PF, Carrondo MA (2004) Substrate and dioxygen binding to the endospore coat laccase from Bacillus subtilis. J Biol Chem 279:23472\u201323476","journal-title":"J Biol Chem"},{"key":"1825_CR54","doi-asserted-by":"crossref","first-page":"3634","DOI":"10.1046\/j.1432-1033.2003.03752.x","volume":"270","author":"F D\u2019Acunzo","year":"2003","unstructured":"D\u2019Acunzo F, Galli C, Masci B (2003) First evidence of catalytic mediation by phenolic compounds in the laccase-induced oxidation of lignin models. Eur J Biochem 270:3634\u20133640","journal-title":"Eur J Biochem"},{"key":"1825_CR55","doi-asserted-by":"crossref","first-page":"4124","DOI":"10.1021\/es062723+","volume":"41","author":"A Guti\u00e9rrez","year":"2007","unstructured":"Guti\u00e9rrez A, Rencoret J, Ibarra D, Camarero S, Del Rio JC, Martinez AT (2007) Removal of lipophilic extractives from paper pulp by laccase and lignin-derived phenols as natural mediators. Environ Sci Technol 41:4124\u20134129","journal-title":"Environ Sci Technol"},{"key":"1825_CR56","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.biotechadv.2010.05.002","volume":"28","author":"AI Ca\u00f1as","year":"2010","unstructured":"Ca\u00f1as AI, Camarero S (2010) Laccases and their natural mediators: biotechnological tools for sustainable eco-friendly processes. Biotechnol Adv 28:694\u2013705","journal-title":"Biotechnol Adv"},{"key":"1825_CR57","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s12275-012-1421-1","volume":"50","author":"R Khlifi-Slama","year":"2012","unstructured":"Khlifi-Slama R, Mechichi T, Sayadi S, Dhouib A (2012) Effect of natural mediators on the stability of Trametes trogii laccase during the decolourization of textile wastewaters. J Microbiol 50:226\u2013234","journal-title":"J Microbiol"},{"key":"1825_CR58","doi-asserted-by":"crossref","unstructured":"Torres-Duarte C, Aguila S, Vazquez-Duhalt R (2011) Syringaldehyde a true laccase mediator. Comments on the Letter to the Editor from Jeon, J-R., Kim, E-J. and Chang, Y-S. Chemosphere 85:1761\u20131762","DOI":"10.1016\/j.chemosphere.2011.07.045"},{"key":"1825_CR59","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1070\/RC1968v037n06ABEH001651","volume":"37","author":"VD Pokhodenko","year":"1968","unstructured":"Pokhodenko VD, Khizhnyi VA, Bidzilya VA (1968) Stable Phenoxy-radicals. Russ Chem Rev 37:435\u2013448","journal-title":"Russ Chem Rev"},{"key":"1825_CR60","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.molcatb.2013.08.013","volume":"97","author":"A Martorana","year":"2013","unstructured":"Martorana A, Sorace L, Boer H, Vazquez-Duhalt R, Basosi R, Baratto MC (2013) A spectroscopic characterization of a phenolic natural mediator in the laccase biocatalytic reaction. J Mol Catal B 97:203\u2013208","journal-title":"J Mol Catal B"},{"key":"1825_CR61","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.enzmictec.2012.10.009","volume":"52","author":"F Medina","year":"2013","unstructured":"Medina F, Aguila SA, Baratto MC, Martorana A, Basosi R, Alderete JB, Vazquez-Duhalt R (2013) Prediction model based on decision tree analysis for laccase mediators. Enzym Microbial Technol 52:68\u201376","journal-title":"Enzym Microbial Technol"},{"key":"1825_CR62","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1021\/bm060038p","volume":"7","author":"A Marjasvaara","year":"2006","unstructured":"Marjasvaara A, Torvinen M, Kinnunen H, Vainiotalo P (2006) Laccase-catalyzed polymerization of two phenolic compounds studied by matrix-assisted laser desorption\/ionization time-of-flight and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry with collision-induced dissociation experiments. Biomacromolecules 7:1604\u20131609","journal-title":"Biomacromolecules"},{"key":"1825_CR63","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1021\/cr00082a003","volume":"87","author":"ET Denisov","year":"1987","unstructured":"Denisov ET, Khudyakov IV (1987) Mechanism of action and reactivities of the free radicals of inhibitors. Chem Rev 87:1313\u20131357","journal-title":"Chem Rev"},{"key":"1825_CR64","unstructured":"Rochester CH, Rossall B (1967) Steric hindrance and acidity. Part I. The effect of 2,6-di-t-butyl substitution on the acidity of phenols in methanol. J Chem Soc B Phys Org 743\u2013748"}],"container-title":["Cellular and Molecular Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-014-1825-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00018-014-1825-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-014-1825-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T10:30:06Z","timestamp":1558521006000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00018-014-1825-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,17]]},"references-count":64,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["1825"],"URL":"https:\/\/doi.org\/10.1007\/s00018-014-1825-7","relation":{},"ISSN":["1420-682X","1420-9071"],"issn-type":[{"value":"1420-682X","type":"print"},{"value":"1420-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,17]]}}}