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In this study, we employed an advanced method to extract venom from the setae and identify the venom components through high-quality\n                    <jats:italic>de novo<\/jats:italic>\n                    transcriptomics, venom proteomics, and bioinformatic analysis. A total of 171 venom components were identified, including allergens, odorant binding proteins, small peptides, enzymes, enzyme inhibitors, and chitin biosynthesis products, potentially responsible for inflammatory and allergic reactions. This work presents the first comprehensive proteotranscriptomic database of\n                    <jats:italic>T. processionea<\/jats:italic>\n                    , contributing to understanding the complexity of lepidopterism. Furthermore, these findings hold promise for advancing therapeutic approaches to mitigate the global health impact of\n                    <jats:italic>T. processionea<\/jats:italic>\n                    and related caterpillars.\n                  <\/jats:p>","DOI":"10.1007\/s00018-024-05330-z","type":"journal-article","created":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T02:02:36Z","timestamp":1722045756000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exploring oak processionary caterpillar induced lepidopterism (Part 1): unveiling molecular insights through transcriptomics and proteomics"],"prefix":"10.1007","volume":"81","author":[{"given":"Andrea","family":"Seldeslachts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius F.","family":"Maurstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Philip","family":"\u00d8yen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eivind Andreas Baste","family":"Undheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Peigneur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1778-6022","authenticated-orcid":false,"given":"Jan","family":"Tytgat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,27]]},"reference":[{"key":"5330_CR1","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3390\/BIOMEDICINES8060143","volume":"8","author":"A Seldeslachts","year":"2020","unstructured":"Seldeslachts A, Peigneur S, Tytgat J (2020) Caterpillar Venom: A Health Hazard of the 21st Century. 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