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Mol. Life Sci."],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Most vertebrates have a <jats:italic>rhodopsin<\/jats:italic> gene with a five-exon structure for visual photoreception. By contrast, teleost fishes have an intron-less <jats:italic>rhodopsin<\/jats:italic> gene for visual photoreception and an intron-containing <jats:italic>rhodopsin<\/jats:italic> (<jats:italic>exo-rhodopsin<\/jats:italic>) gene for pineal photoreception. Here, our analysis of non-teleost and teleost fishes in various lineages of the Actinopterygii reveals that retroduplication after branching of the Polypteriformes produced the intron-less <jats:italic>rhodopsin<\/jats:italic> gene for visual photoreception, which converted the parental intron-containing <jats:italic>rhodopsin<\/jats:italic> gene into a pineal opsin in the common ancestor of the Teleostei. Additional analysis of a pineal opsin, pinopsin, shows that the <jats:italic>pinopsin<\/jats:italic> gene functions as a green-sensitive opsin together with the intron-containing <jats:italic>rhodopsin<\/jats:italic> gene for pineal photoreception in tarpon as an evolutionary intermediate state but is missing in other teleost fishes, probably because of the redundancy with the intron-containing <jats:italic>rhodopsin<\/jats:italic> gene. We propose an evolutionary scenario where unique retroduplication caused a \u201cdomino effect\u201d on the functional diversification of teleost visual and pineal opsin genes.<\/jats:p>","DOI":"10.1007\/s00018-024-05461-3","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T17:02:11Z","timestamp":1728406931000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Functional diversification process of opsin genes for teleost visual and pineal photoreceptions"],"prefix":"10.1007","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9289-7406","authenticated-orcid":false,"given":"Chihiro","family":"Fujiyabu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7187-7163","authenticated-orcid":false,"given":"Fuki","family":"Gyoja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7089-2951","authenticated-orcid":false,"given":"Keita","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9360-2144","authenticated-orcid":false,"given":"Emi","family":"Kawano-Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1961-606X","authenticated-orcid":false,"given":"Hideyo","family":"Ohuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8325-3665","authenticated-orcid":false,"given":"Takehiro G.","family":"Kusakabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7956-9288","authenticated-orcid":false,"given":"Takahiro","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"5461_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/gb-2005-6-3-213","volume":"6","author":"A Terakita","year":"2005","unstructured":"Terakita A (2005) The opsins. 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The experiments in this report were approved by the Animal Care and Use Committee of Kyoto University (permit number: 202304 and 202404).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All data are available in the main text or the supplementary materials. The sequences reported in this paper have been deposited in the GenBank database (accession numbers: LC818093\u2009~\u2009LC818097).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}}],"article-number":"428"}}