{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T23:36:53Z","timestamp":1788219413929,"version":"build-2803163510"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Key specialized research and development breakthrough of Henan Province","award":["242102311071"],"award-info":[{"award-number":["242102311071"]}]},{"name":"the Startup Foundation for Doctor of Xinxiang Medical University","award":["XYBSKYZZ202159"],"award-info":[{"award-number":["XYBSKYZZ202159"]}]},{"DOI":"10.13039\/501100001809","name":"The National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82070895"],"award-info":[{"award-number":["82070895"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100006407","name":"Natural Science Foundation of Henan Province","doi-asserted-by":"publisher","award":["232300421047"],"award-info":[{"award-number":["232300421047"]}],"id":[{"id":"10.13039\/501100006407","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Technology Innovation Talents in Universities of Henan Province","award":["24HASTIT067"],"award-info":[{"award-number":["24HASTIT067"]}]},{"DOI":"10.13039\/501100019595","name":"Youth and Middle-aged Scientific and Technological Innovation Leading Talents Program of the Corps","doi-asserted-by":"publisher","award":["JQEC2023001"],"award-info":[{"award-number":["JQEC2023001"]}],"id":[{"id":"10.13039\/501100019595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015800","name":"Jilin Province Development and Reform Commission","doi-asserted-by":"publisher","award":["YJS2023AL058"],"award-info":[{"award-number":["YJS2023AL058"]}],"id":[{"id":"10.13039\/100015800","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell. Mol. Life Sci."],"DOI":"10.1007\/s00018-024-05555-y","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T10:31:24Z","timestamp":1736159484000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Downregulation of FcRn promotes ferroptosis in herpes simplex virus-1-induced lung injury"],"prefix":"10.1007","volume":"82","author":[{"given":"Shaoju","family":"Qian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danqiong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruixue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Sha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianfeng","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiesuo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangfeng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5832-1024","authenticated-orcid":false,"given":"Lili","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,6]]},"reference":[{"key":"5555_CR1","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1111\/j.1469-0691.2006.01475.x","volume":"12","author":"AM Simoons-Smit","year":"2006","unstructured":"Simoons-Smit AM, Kraan EM, Beishuizen A, Strack van Schijndel RJ, Vandenbroucke-Grauls CM (2006) Herpes simplex virus type 1 and respiratory disease in critically-ill patients Real pathogen or innocent bystander? Clin Microbiol Infect 12:1050\u20131059. https:\/\/doi.org\/10.1111\/j.1469-0691.2006.01475.x","journal-title":"Clin Microbiol Infect"},{"key":"5555_CR2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/nri2937","volume":"11","author":"SR Paludan","year":"2006","unstructured":"Paludan SR, Bowie AG, Horan KA, Fitzgerald KA (2006) Recognition of herpesviruses by the innate immune system. Nat Rev Immunol 11:143\u2013154. https:\/\/doi.org\/10.1038\/nri2937","journal-title":"Nat Rev Immunol"},{"key":"5555_CR3","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1007\/s13238-012-2021-x","volume":"3","author":"S Wang","year":"2012","unstructured":"Wang S, Long J, Zheng CF (2012) The potential link between PML NBs and ICP0 in regulating lytic and latent infection of HSV-1. Protein Cell 3:372\u2013382. https:\/\/doi.org\/10.1007\/s13238-012-2021-x","journal-title":"Protein Cell"},{"key":"5555_CR4","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1186\/s12934-024-02517-8","volume":"23","author":"S Qian","year":"2024","unstructured":"Qian S, Li R, He Y, Wang H, Zhang D, Sun A et al (2024) Immunogenicity and protective efficacy of a recombinant Lactococcus lactis vaccine against HSV-1 infection. Microbial Cell Factor 23:244. https:\/\/doi.org\/10.1186\/s12934-024-02517-8","journal-title":"Microbial Cell Factor"},{"key":"5555_CR5","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3103\/s0891416818020076","volume":"33","author":"MA Efimova","year":"2018","unstructured":"Efimova MA, Mahmud RS, Nikitin AI, Chernov AN, Kolpakov AI, Ilinskaya ON (2018) Ribonuclease from Bacillus pumilus Prevents HSV-1 entrance into the cell and reproduction. Mol Genet Microbiol Virol 33:147\u2013150. https:\/\/doi.org\/10.3103\/s0891416818020076","journal-title":"Mol Genet Microbiol Virol"},{"key":"5555_CR6","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1038\/nri2937","volume":"21","author":"L Koujah","year":"2021","unstructured":"Koujah L, Allaham M, Patil CD, Ames JM, Suryawanshi RK, Yadavalli T et al (2021) Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies. Ocul Surf 21:238\u2013249. https:\/\/doi.org\/10.1038\/nri2937","journal-title":"Ocul Surf"},{"key":"5555_CR7","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.jcrc.2015.11.019","volume":"32","author":"B Saugel","year":"2016","unstructured":"Saugel B, Jakobus J, Huber W, Hoffmann D, Holzapfel K, Protzer U et al (2016) Herpes simplex virus in bronchoalveolar lavage fluid of medical intensive care unit patients: association with lung injury and outcome. J Crit Care 32:138\u2013144. https:\/\/doi.org\/10.1016\/j.jcrc.2015.11.019","journal-title":"J Crit Care"},{"key":"5555_CR8","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s00430-016-0456-z","volume":"205","author":"M Bonizzoli","year":"2016","unstructured":"Bonizzoli M, Arvia R, di Valvasone S, Liotta F, Zakrzewska K, Azzi A et al (2016) Human herpesviruses respiratory infections in patients with acute respiratory distress (ARDS). Med Microbiol Immunol 205:371\u2013379. https:\/\/doi.org\/10.1007\/s00430-016-0456-z","journal-title":"Med Microbiol Immunol"},{"key":"5555_CR9","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1159\/000355200","volume":"87","author":"R Tachikawa","year":"2014","unstructured":"Tachikawa R, Tomii K, Seo R, Nagata K, Otsuka K, Nakagawa A et al (2014) Detection of herpes viruses by multiplex and real-time polymerase chain reaction in bronchoalveolar lavage fluid of patients with acute lung injury or acute respiratory distress syndrome. Respi Int Rev Thoracic Dis 87:279\u2013286. https:\/\/doi.org\/10.1159\/000355200","journal-title":"Respi Int Rev Thoracic Dis"},{"key":"5555_CR10","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1128\/cvi.00170-15","volume":"22","author":"B Wu","year":"2015","unstructured":"Wu B, Geng S, Bi Y, Liu H, Hu Y, Li X et al (2015) Herpes simplex virus 1 suppresses the function of lung dendritic cells via caveolin-1. Clin Vacc Immunolo 22:883\u2013895. https:\/\/doi.org\/10.1128\/cvi.00170-15","journal-title":"Clin Vacc Immunolo"},{"key":"5555_CR11","doi-asserted-by":"publisher","DOI":"10.1128\/mmbr.00099-20","author":"H Zhu","year":"2020","unstructured":"Zhu H, Zheng C (2020) The race between host antiviral innate immunity and the immune evasion strategies of herpes simplex virus 1. Microbiol Mol Biol Rev. https:\/\/doi.org\/10.1128\/mmbr.00099-20","journal-title":"Microbiol Mol Biol Rev"},{"key":"5555_CR12","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.vetimm.2004.06.008","volume":"102","author":"I Kacskovics","year":"2004","unstructured":"Kacskovics I (2004) Fc receptors in livestock species. Veter Immunol Immunopathol 102:351\u2013362. https:\/\/doi.org\/10.1016\/j.vetimm.2004.06.008","journal-title":"Veter Immunol Immunopathol"},{"key":"5555_CR13","doi-asserted-by":"publisher","first-page":"4388","DOI":"10.1073\/pnas.1012861108","volume":"108","author":"Z Li","year":"2011","unstructured":"Li Z, Palaniyandi S, Zeng R, Tuo W, Roopenian DC, Zhu X (2011) Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection. Proc Natl Acad Sci USA 108:4388\u20134393. https:\/\/doi.org\/10.1073\/pnas.1012861108","journal-title":"Proc Natl Acad Sci USA"},{"key":"5555_CR14","doi-asserted-by":"publisher","first-page":"7550","DOI":"10.1128\/jvi.00493-13","volume":"87","author":"D Kruijsen","year":"2013","unstructured":"Kruijsen D, Einarsdottir HK, Schijf MA, Coenjaerts FE, van der Schoot EC, Vidarsson G et al (2013) Intranasal administration of antibody-bound respiratory syncytial virus particles efficiently primes virus-specific immune responses in mice. J Virol 87:7550\u20137557. https:\/\/doi.org\/10.1128\/jvi.00493-13","journal-title":"J Virol"},{"key":"5555_CR15","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.4049\/jimmunol.2100297","volume":"207","author":"SP Ochsner","year":"2021","unstructured":"Ochsner SP, Li W, Rajendrakumar AM, Palaniyandi S, Acharya G, Liu X et al (2021) FcRn-targeted mucosal vaccination against influenza virus infection. J Immunol (Baltimore, Md.: 1950) 207:1310\u20131321. https:\/\/doi.org\/10.4049\/jimmunol.2100297","journal-title":"J Immunol (Baltimore, Md.: 1950)"},{"key":"5555_CR16","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.2353\/ajpath.2006.050482","volume":"168","author":"E Maidji","year":"2006","unstructured":"Maidji E, McDonagh S, Genbacev O, Tabata T, Pereira L (2006) Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis. Am J Pathol 168:1210\u20131226. https:\/\/doi.org\/10.2353\/ajpath.2006.050482","journal-title":"Am J Pathol"},{"key":"5555_CR17","doi-asserted-by":"publisher","first-page":"739392","DOI":"10.3389\/fcell.2021.739392","volume":"9","author":"Y Liu","year":"2021","unstructured":"Liu Y, Duan C, Dai R, Zeng Y (2021) Ferroptosis-mediated crosstalk in the tumor microenvironment implicated in cancer progression and therapy. Front Cell Dev Biol 9:739392. https:\/\/doi.org\/10.3389\/fcell.2021.739392","journal-title":"Front Cell Dev Biol"},{"issue":"Suppl 2","key":"5555_CR18","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1038\/sj.cdd.4401724","volume":"12","author":"G Kroemer","year":"2011","unstructured":"Kroemer G, El-Deiry WS, Golstein P, Peter ME, Vaux D, Vandenabeele P et al (2011) Classification of cell death: recommendations of the nomenclature committee on cell death. Cell Death Differ 12(Suppl 2):1463\u20131467. https:\/\/doi.org\/10.1038\/sj.cdd.4401724","journal-title":"Cell Death Differ"},{"key":"5555_CR19","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/s41586-019-1707-0","volume":"575","author":"S Doll","year":"2019","unstructured":"Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I et al (2019) FSP1 is a glutathione-independent ferroptosis suppressor. Nature 575:693\u2013698. https:\/\/doi.org\/10.1038\/s41586-019-1707-0","journal-title":"Nature"},{"key":"5555_CR20","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s11658-020-00205-0","volume":"25","author":"P Liu","year":"2020","unstructured":"Liu P, Feng Y, Li H, Chen X, Wang G, Xu S et al (2020) Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis. Cell Mol Biol Lett 25:10. https:\/\/doi.org\/10.1186\/s11658-020-00205-0","journal-title":"Cell Mol Biol Lett"},{"key":"5555_CR21","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1038\/s41419-022-04971-x","volume":"13","author":"Y Yang","year":"2022","unstructured":"Yang Y, Ma Y, Li Q, Ling Y, Zhou Y, Chu K et al (2022) STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53\/SLC7A11 pathway. Cell Death Dis 13:530. https:\/\/doi.org\/10.1038\/s41419-022-04971-x","journal-title":"Cell Death Dis"},{"key":"5555_CR22","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1084\/jem.20181776","volume":"216","author":"EP Amaral","year":"2024","unstructured":"Amaral EP, Costa DL, Namasivayam S, Riteau N, Kamenyeva O, Mittereder L et al (2024) A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis. J Exp Med 216:556\u2013570. https:\/\/doi.org\/10.1084\/jem.20181776","journal-title":"J Exp Med"},{"key":"5555_CR23","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1186\/s12985-022-01825-y","volume":"19","author":"J Cheng","year":"2022","unstructured":"Cheng J, Tao J, Li B, Shi Y, Liu H (2022) Swine influenza virus triggers ferroptosis in A549 cells to enhance virus replication. Virol J 19:104. https:\/\/doi.org\/10.1186\/s12985-022-01825-y","journal-title":"Virol J"},{"key":"5555_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2022.04.014","volume":"186","author":"Y Wang","year":"2022","unstructured":"Wang Y, Liao S, Pan Z, Jiang S, Fan J, Yu S et al (2022) Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis. Free Radical Biol Med 186:1\u201316. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2022.04.014","journal-title":"Free Radical Biol Med"},{"key":"5555_CR25","doi-asserted-by":"publisher","first-page":"0237022","DOI":"10.1128\/mbio.02370-22","volume":"14","author":"XQ Xu","year":"2023","unstructured":"Xu XQ, Xu T, Ji W, Wang C, Ren Y, Xiong X et al (2023) Herpes simplex virus 1-induced ferroptosis contributes to viral encephalitis. MBio 14:0237022. https:\/\/doi.org\/10.1128\/mbio.02370-22","journal-title":"MBio"},{"key":"5555_CR26","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1128\/JVI.01730-10","volume":"85","author":"J Xing","year":"2011","unstructured":"Xing J, Wang S, Lin F, Pan W, Hu CD, Zheng C (2011) Comprehensive characterization of interaction complexes of herpes simplex virus type 1 ICP22, UL3, UL4, and UL20.5. J Virol 85:1881\u20131886. https:\/\/doi.org\/10.1128\/JVI.01730-10","journal-title":"J Virol"},{"key":"5555_CR27","doi-asserted-by":"publisher","first-page":"101444","DOI":"10.1016\/j.redox.2020.101444","volume":"32","author":"Y Liu","year":"2020","unstructured":"Liu Y, Tian X, Liu S, Liu D, Li Y, Liu M et al (2020) DNA hypermethylation: a novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction. Redox Biol 32:101444. https:\/\/doi.org\/10.1016\/j.redox.2020.101444","journal-title":"Redox Biol"},{"key":"5555_CR28","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.freeradbiomed.2024.09.010","volume":"224","author":"S Qian","year":"2024","unstructured":"Qian S, Yang Z, Zhang X, Li R, Sun Y, Zhang Z et al (2024) Novel therapeutic approach for psoriasis: upregulating FcRn to inhibit ferroptosis and alleviate lesional skin. Free Radical Biol Med 224:797\u2013808. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2024.09.010","journal-title":"Free Radical Biol Med"},{"key":"5555_CR29","doi-asserted-by":"publisher","first-page":"3758","DOI":"10.1073\/pnas.1817341116","volume":"116","author":"S Morosky","year":"2019","unstructured":"Morosky S, Wells AI, Lemon K, Evans AS, Schamus S, Bakkenist CJ et al (2019) The neonatal Fc receptor is a pan-echovirus receptor. Proc Natl Acad Sci USA 116:3758\u20133763. https:\/\/doi.org\/10.1073\/pnas.1817341116","journal-title":"Proc Natl Acad Sci USA"},{"key":"5555_CR30","doi-asserted-by":"publisher","first-page":"3020","DOI":"10.1038\/s41467-019-10865-y","volume":"10","author":"X Liu","year":"2019","unstructured":"Liu X, Palaniyandi S, Zhu I, Tang J, Li W, Wu X et al (2019) Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor. Nat Commun 10:3020. https:\/\/doi.org\/10.1038\/s41467-019-10865-y","journal-title":"Nat Commun"},{"key":"5555_CR31","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s12985-016-0495-5","volume":"13","author":"C Su","year":"2023","unstructured":"Su C, Zhan G, Zheng C (2023) Evasion of host antiviral innate immunity by HSV-1, an update. Virol J 13:38","journal-title":"Virol J"},{"key":"5555_CR32","doi-asserted-by":"publisher","first-page":"2526","DOI":"10.1016\/j.vaccine.2021.03.075","volume":"39","author":"DJJ Carr","year":"2021","unstructured":"Carr DJJ, Berube AN, Filiberti A, Gmyrek GB (2021) Lack of neonatal Fc receptor does not diminish the efficacy of the HSV-1 0DeltaNLS vaccine against ocular HSV-1 challenge. Vaccine 39:2526\u20132536. https:\/\/doi.org\/10.1016\/j.vaccine.2021.03.075","journal-title":"Vaccine"},{"key":"5555_CR33","doi-asserted-by":"publisher","first-page":"1898","DOI":"10.4049\/jimmunol.1700316","volume":"199","author":"DJ Royer","year":"2017","unstructured":"Royer DJ, Carr MM, Gurung HR, Halford WP, Carr DJJ (2017) The Neonatal Fc receptor and complement fixation facilitate prophylactic vaccine-mediated humoral protection against viral infection in the ocular mucosa. J Immunol (Baltimore, Md: 1950) 199:1898\u20131911. https:\/\/doi.org\/10.4049\/jimmunol.1700316","journal-title":"J Immunol (Baltimore, Md: 1950)"},{"key":"5555_CR34","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1038\/s41576-018-0004-3","volume":"19","author":"S Horvath","year":"2018","unstructured":"Horvath S, Raj K (2018) DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet 19:371\u2013384. https:\/\/doi.org\/10.1038\/s41576-018-0004-3","journal-title":"Nat Rev Genet"},{"key":"5555_CR35","doi-asserted-by":"publisher","first-page":"1968","DOI":"10.1002\/pmic.201500035","volume":"15","author":"DL Rowles","year":"2015","unstructured":"Rowles DL, Tsai YC, Greco TM, Lin AE, Li M, Yeh J et al (2015) DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection. Proteomics 15:1968\u20131982. https:\/\/doi.org\/10.1002\/pmic.201500035","journal-title":"Proteomics"},{"key":"5555_CR36","doi-asserted-by":"publisher","first-page":"100545","DOI":"10.1016\/j.bbih.2022.100545","volume":"26","author":"R Osaka","year":"2022","unstructured":"Osaka R, Kobayashi N, Shimada K, Ishii A, Oka N, Kondo K (2022) VP26, a herpes simplex virus type 1 capsid protein, increases DNA methylation in COASY promoter region. Brain Behav Immunity Health 26:100545. https:\/\/doi.org\/10.1016\/j.bbih.2022.100545","journal-title":"Brain Behav Immunity Health"},{"key":"5555_CR37","doi-asserted-by":"publisher","first-page":"8674","DOI":"10.1038\/s41598-019-45203-1","volume":"9","author":"RB Cejas","year":"2019","unstructured":"Cejas RB, Ferguson DC, Qui\u00f1ones-Lombra\u00f1a A, Bard JE, Blanco JG (2019) Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium. Sci Rep 9:8674. https:\/\/doi.org\/10.1038\/s41598-019-45203-1","journal-title":"Sci Rep"},{"key":"5555_CR38","doi-asserted-by":"publisher","first-page":"e0135141","DOI":"10.1371\/journal.pone.0135141","volume":"10","author":"JE Mikulska","year":"2015","unstructured":"Mikulska JE (2015) Analysis of response elements involved in the regulation of the human neonatal Fc receptor gene (FCGRT). PLoS ONE 10:e0135141. https:\/\/doi.org\/10.1371\/journal.pone.0135141","journal-title":"PLoS ONE"},{"key":"5555_CR39","doi-asserted-by":"publisher","first-page":"475","DOI":"10.4049\/jimmunol.2200291","volume":"210","author":"X Jia","year":"2023","unstructured":"Jia X, Chen J, Qiao C, Li C, Yang K, Zhang Y et al (2023) Porcine epidemic diarrhea virus nsp13 protein downregulates neonatal Fc receptor expression by causing promoter hypermethylation through the NF-\u03baB signaling pathway. J Immunol (Baltimore, Md: 1950) 210:475\u2013485. https:\/\/doi.org\/10.4049\/jimmunol.2200291","journal-title":"J Immunol (Baltimore, Md: 1950)"},{"key":"5555_CR40","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9040879","author":"S Qian","year":"2021","unstructured":"Qian S, Li C, Liu X, Jia X, Xiao Y, Li Z (2021) Activation of the JNK\/MAPK signaling pathway by TGF-\u03b21 enhances neonatal Fc receptor expression and IgG transcytosis. Microorganisms. https:\/\/doi.org\/10.3390\/microorganisms9040879","journal-title":"Microorganisms"},{"key":"5555_CR41","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","volume":"31","author":"D Tang","year":"2021","unstructured":"Tang D, Chen X, Kang R, Kroemer G (2021) Ferroptosis: molecular mechanisms and health implications. Cell Res 31:107\u2013125. https:\/\/doi.org\/10.1038\/s41422-020-00441-1","journal-title":"Cell Res"},{"key":"5555_CR42","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","volume":"171","author":"BR Stockwell","year":"2017","unstructured":"Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ et al (2017) Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. Cell 171:273\u2013285. https:\/\/doi.org\/10.1016\/j.cell.2017.09.021","journal-title":"Cell"},{"key":"5555_CR43","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1016\/j.tim.2022.11.006","volume":"31","author":"J Gao","year":"2023","unstructured":"Gao J, Wang Q, Tang YD, Zhai J, Hu W, Zheng C (2023) When ferroptosis meets pathogenic infections. Trends Microbiol 31:468\u2013479. https:\/\/doi.org\/10.1016\/j.tim.2022.11.006","journal-title":"Trends Microbiol"},{"key":"5555_CR44","doi-asserted-by":"publisher","first-page":"12943","DOI":"10.18632\/aging.103378","volume":"12","author":"H Dong","year":"2020","unstructured":"Dong H, Qiang Z, Chai D, Peng J, Xia Y, Hu R et al (2020) Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1. Aging 12:12943\u201312959. https:\/\/doi.org\/10.18632\/aging.103378","journal-title":"Aging"}],"container-title":["Cellular and Molecular Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-024-05555-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00018-024-05555-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-024-05555-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T11:12:33Z","timestamp":1736161953000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00018-024-05555-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,6]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5555"],"URL":"https:\/\/doi.org\/10.1007\/s00018-024-05555-y","relation":{},"ISSN":["1420-9071"],"issn-type":[{"value":"1420-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,6]]},"assertion":[{"value":"17 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}},{"value":"The study was approved by the Local Ethics Committee and Institutional Review Board of the First Affiliated Hospital of Xinxiang Medical University (Approval No. EC-024-345). All animal experiments were carried out following the guidelines for the use and care of experimental animals and were approved by the Ethics Committee of Xinxiang Medical University, China (approval number XYLL-20230134).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All the authors have read and approved the fnal version of the manuscript and agreed to its publication in Cellular and Molecular Life Sciences.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}],"article-number":"36"}}