{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T02:44:58Z","timestamp":1785811498799,"version":"3.56.0"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":64,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2018YFC1003200"],"award-info":[{"award-number":["2018YFC1003200"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32170559"],"award-info":[{"award-number":["32170559"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell. Mol. Life Sci."],"DOI":"10.1007\/s00018-026-06232-y","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T02:03:37Z","timestamp":1780279417000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Peroxisomal DBP deficiency causes male infertility through disruption of lipid homeostasis in Drosophila"],"prefix":"10.1007","volume":"83","author":[{"given":"Jia","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanbin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunbo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jichen","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1334-2723","authenticated-orcid":false,"given":"Wanzhong","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"6232_CR1","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1002\/ana.20702","volume":"59","author":"S Ferdinandusse","year":"2006","unstructured":"Ferdinandusse S et al (2006) Clinical and biochemical spectrum of D-bifunctional protein deficiency. Ann Neurol 59:92\u2013104","journal-title":"Ann Neurol"},{"key":"6232_CR2","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1093\/oxfordjournals.jbchem.a021615","volume":"121","author":"LL Jiang","year":"1997","unstructured":"Jiang LL, Kurosawa T, Sato M, Suzuki Y, Hashimoto T (1997) Physiological role of D-3-Hydroxyacyl-CoA Dehydratase\/D-3-Hydroxyacyl-CoA Dehydrogenase Bifunctional Protein. J Biochem (Tokyo) 121:506\u2013513","journal-title":"J Biochem (Tokyo)"},{"key":"6232_CR3","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1016\/j.bbamcr.2006.08.010","volume":"1763","author":"RJA Wanders","year":"2006","unstructured":"Wanders RJA, Waterham HR (2006) Peroxisomal disorders: the single peroxisomal enzyme deficiencies. Biochim Biophys Acta BBA - Mol Cell Res 1763:1707\u20131720","journal-title":"Biochim Biophys Acta BBA - Mol Cell Res"},{"key":"6232_CR4","doi-asserted-by":"publisher","DOI":"10.1212\/NXG.0000000000000114","volume":"2","author":"DJ Amor","year":"2016","unstructured":"Amor DJ et al (2016) Heterozygous mutations in HSD17B4 cause juvenile peroxisomal D-bifunctional protein deficiency. Neurol Genet 2:e114","journal-title":"Neurol Genet"},{"key":"6232_CR5","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.jns.2016.11.009","volume":"372","author":"T Matsukawa","year":"2017","unstructured":"Matsukawa T et al (2017) Slowly progressive D-bifunctional protein deficiency with survival to adulthood diagnosed by whole-exome sequencing. J Neurol Sci 372:6\u201310","journal-title":"J Neurol Sci"},{"key":"6232_CR6","doi-asserted-by":"publisher","DOI":"10.1212\/NXG.0000000000000396","volume":"6","author":"Y Matsuda","year":"2020","unstructured":"Matsuda Y et al (2020) Biallelic mutation of HSD17B4 induces middle age\u2013onset spinocerebellar ataxia. Neurol Genet 6:e396","journal-title":"Neurol Genet"},{"key":"6232_CR7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-15-30","volume":"15","author":"DS Lieber","year":"2014","unstructured":"Lieber DS et al (2014) Next generation sequencing with copy number variant detection expands the phenotypic spectrum of HSD17B4-deficiency. BMC Med Genet 15:30","journal-title":"BMC Med Genet"},{"key":"6232_CR8","doi-asserted-by":"publisher","first-page":"2228","DOI":"10.1210\/en.2005-1571","volume":"147","author":"S Huyghe","year":"2006","unstructured":"Huyghe S et al (2006) Peroxisomal Multifunctional Protein 2 is essential for lipid homeostasis in Sertoli Cells and male fertility in mice. Endocrinology 147:2228\u20132236","journal-title":"Endocrinology"},{"key":"6232_CR9","doi-asserted-by":"publisher","first-page":"870","DOI":"10.3390\/insects15110870","volume":"15","author":"S Casas-Tint\u00f3","year":"2024","unstructured":"Casas-Tint\u00f3 S (2024) Drosophila as a model for human disease: insights into rare and ultra-rare diseases. Insects 15:870","journal-title":"Insects"},{"key":"6232_CR10","doi-asserted-by":"publisher","first-page":"197","DOI":"10.4161\/spmg.21798","volume":"2","author":"L Fabian","year":"2012","unstructured":"Fabian L, Brill JA (2012) Drosophila spermiogenesis: big things come from little packages. Spermatogenesis 2:197\u2013212","journal-title":"Spermatogenesis"},{"key":"6232_CR11","first-page":"433","volume":"9","author":"MT Fuller","year":"1998","unstructured":"Fuller MT (1998) Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Cell Dev Biol 9:433\u2013444","journal-title":"Cell Dev Biol"},{"key":"6232_CR12","doi-asserted-by":"publisher","first-page":"835","DOI":"10.3389\/fcell.2020.00835","volume":"8","author":"C Pridie","year":"2020","unstructured":"Pridie C, Ueda K, Simmonds AJ (2020) Rosy beginnings: studying peroxisomes in Drosophila. Front Cell Dev Biol 8:835","journal-title":"Front Cell Dev Biol"},{"key":"6232_CR13","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1016\/j.bbamcr.2006.09.010","volume":"1763","author":"SJ Steinberg","year":"2006","unstructured":"Steinberg SJ et al (2006) Peroxisome biogenesis disorders. Biochim Biophys Acta BBA Mol Cell Res 1763:1733\u20131748","journal-title":"Biochim Biophys Acta BBA Mol Cell Res"},{"key":"6232_CR14","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1242\/dmm.007419","volume":"4","author":"FD Mast","year":"2011","unstructured":"Mast FD et al (2011) A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders. Dis Model Mech 4:659\u2013672","journal-title":"Dis Model Mech"},{"key":"6232_CR15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022984","volume":"6","author":"M Nakayama","year":"2011","unstructured":"Nakayama M et al (2011) Drosophila carrying Pex3 or Pex16 mutations are models of Zellweger syndrome that reflect its symptoms associated with the absence of peroxisomes. PLoS One 6:e22984","journal-title":"PLoS One"},{"key":"6232_CR16","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1093\/hmg\/ddp518","volume":"19","author":"H Chen","year":"2010","unstructured":"Chen H, Liu Z, Huang X (2010) Drosophila models of peroxisomal biogenesis disorder: peroxins are required for spermatogenesis and very-long-chain fatty acid metabolism. Hum Mol Genet 19:494\u2013505","journal-title":"Hum Mol Genet"},{"key":"6232_CR17","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwae215","volume":"11","author":"R Zhang","year":"2024","unstructured":"Zhang R et al (2024) Soma-germline communication drives sex maintenance in the Drosophila testis. Natl Sci Rev 11:nwae215","journal-title":"Natl Sci Rev"},{"key":"6232_CR18","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.47138","volume":"8","author":"E Witt","year":"2019","unstructured":"Witt E, Benjamin S, Svetec N, Zhao L (2019) Testis single-cell RNA-seq reveals the dynamics of de novo gene transcription and germline mutational bias in Drosophila. eLife 8:e47138","journal-title":"eLife"},{"key":"6232_CR19","doi-asserted-by":"publisher","DOI":"10.1126\/science.abk2432","volume":"375","author":"H Li","year":"2022","unstructured":"Li H et al (2022) Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly. Science 375:eabk2432","journal-title":"Science"},{"key":"6232_CR20","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.82201","volume":"12","author":"AA Raz","year":"2023","unstructured":"Raz AA et al (2023) Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes. eLife 12:e82201","journal-title":"eLife"},{"key":"6232_CR21","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.devcel.2014.10.004","volume":"31","author":"Q Ma","year":"2014","unstructured":"Ma Q, Wawersik M, Matunis EL (2014) The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche. Dev Cell 31:474\u2013486","journal-title":"Dev Cell"},{"key":"6232_CR22","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.ydbio.2006.02.048","volume":"294","author":"NA Terry","year":"2006","unstructured":"Terry NA, Tulina N, Matunis E, DiNardo S (2006) Novel regulators revealed by profiling Drosophila testis stem cells within their niche. Dev Biol 294:246\u2013257","journal-title":"Dev Biol"},{"key":"6232_CR23","doi-asserted-by":"publisher","first-page":"9304","DOI":"10.1073\/pnas.0901452106","volume":"106","author":"Y Li","year":"2009","unstructured":"Li Y, Minor NT, Park JK, McKearin DM, Maines JZ (2009) Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance. Proc Natl Acad Sci U S A 106:9304\u20139309","journal-title":"Proc Natl Acad Sci U S A"},{"key":"6232_CR24","doi-asserted-by":"publisher","first-page":"22311","DOI":"10.1073\/pnas.0912454106","volume":"106","author":"ML Insco","year":"2009","unstructured":"Insco ML, Leon A, Tam CH, McKearin DM, Fuller MT (2009) Accumulation of a differentiation regulator specifies transit amplifying division number in an adult stem cell lineage. Proc Natl Acad Sci U S A 106:22311\u201322316","journal-title":"Proc Natl Acad Sci U S A"},{"key":"6232_CR25","doi-asserted-by":"publisher","first-page":"2863","DOI":"10.1242\/dev.003764","volume":"134","author":"CC Baker","year":"2007","unstructured":"Baker CC, Fuller MT (2007) Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog. Development 134:2863\u20132869","journal-title":"Development"},{"key":"6232_CR26","doi-asserted-by":"publisher","first-page":"2411","DOI":"10.1007\/s11427-024-2646-3","volume":"67","author":"Y Fang","year":"2024","unstructured":"Fang Y et al (2024) RpL38 modulates germ cell differentiation by controlling Bam expression in Drosophila testis. Sci China Life Sci 67:2411\u20132425","journal-title":"Sci China Life Sci"},{"key":"6232_CR27","doi-asserted-by":"crossref","unstructured":"Li, A. Y. Z. et al (2023) Milton assembles large mitochondrial clusters, mitoballs, to sustain spermatogenesis. Proc Natl Acad Sci 120:e2306073120","DOI":"10.1073\/pnas.2306073120"},{"key":"6232_CR28","doi-asserted-by":"crossref","unstructured":"Inaba M, Yamashita YM (2017) Evaluation of the Asymmetric Division of Drosophila Male Germline Stem Cells. In: Buszczak M (ed) Germline Stem Cells, vol 1463. Springer New York, New York, NY, pp 49\u201362","DOI":"10.1007\/978-1-4939-4017-2_3"},{"key":"6232_CR29","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1038\/nature07386","volume":"456","author":"J Cheng","year":"2008","unstructured":"Cheng J et al (2008) Centrosome misorientation reduces stem cell division during ageing. Nature 456:599\u2013604","journal-title":"Nature"},{"key":"6232_CR30","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1126\/science.1087795","volume":"301","author":"YM Yamashita","year":"2003","unstructured":"Yamashita YM, Jones DL, Fuller MT (2003) Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science 301:1547\u20131550","journal-title":"Science"},{"key":"6232_CR31","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1093\/hmg\/ddab107","volume":"30","author":"J Wu","year":"2021","unstructured":"Wu J et al (2021) RNA kinase CLP1\/Cbc regulates meiosis initiation in spermatogenesis. Hum Mol Genet 30:1569\u20131578","journal-title":"Hum Mol Genet"},{"key":"6232_CR32","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25073980","volume":"25","author":"V Vedelek","year":"2024","unstructured":"Vedelek V, Jankovics F, Z\u00e1dori J, Sinka R (2024) Mitochondrial differentiation during spermatogenesis: lessons from Drosophila melanogaster. Int J Mol Sci 25:3980","journal-title":"Int J Mol Sci"},{"key":"6232_CR33","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1002\/cm.21063","volume":"69","author":"MG Giansanti","year":"2012","unstructured":"Giansanti MG, Fuller MT (2012) What Drosophila spermatocytes tell us about the mechanisms underlying cytokinesis. Cytoskeleton 69:869\u2013881","journal-title":"Cytoskeleton"},{"key":"6232_CR34","doi-asserted-by":"publisher","first-page":"185","DOI":"10.4161\/spmg.21711","volume":"2","author":"MG Giansanti","year":"2012","unstructured":"Giansanti MG, Sechi S, Frappaolo A, Belloni G, Piergentili R (2012) Cytokinesis in Drosophila male meiosis. Spermatogenesis 2:185\u2013196","journal-title":"Spermatogenesis"},{"key":"6232_CR35","doi-asserted-by":"publisher","first-page":"695","DOI":"10.3390\/cells11040695","volume":"11","author":"A Frappaolo","year":"2022","unstructured":"Frappaolo A, Piergentili R, Giansanti MG (2022) Microtubule and actin cytoskeletal dynamics in male meiotic cells of Drosophila melanogaster. Cells 11:695","journal-title":"Cells"},{"key":"6232_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/cells11243977","volume":"11","author":"G Kunduri","year":"2022","unstructured":"Kunduri G, Acharya U, Acharya JK (2022) Lipid polarization during cytokinesis. Cells 11:3977","journal-title":"Cells"},{"key":"6232_CR37","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1146\/annurev-biochem-062917-012448","volume":"87","author":"EM Storck","year":"2018","unstructured":"Storck EM, \u00d6zbalci C, Eggert US (2018) Lipid cell biology: a focus on lipids in cell division. Annu Rev Biochem 87:839\u2013869","journal-title":"Annu Rev Biochem"},{"key":"6232_CR38","doi-asserted-by":"crossref","unstructured":"Kunduri G et al (2022) Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis. PLOS Biol 20(9), e3001599","DOI":"10.1371\/journal.pbio.3001599"},{"key":"6232_CR39","doi-asserted-by":"publisher","DOI":"10.7555\/JBR.37.20230055","volume":"38","author":"Y Yao","year":"2024","unstructured":"Yao Y et al (2024) Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis. J Biomed Res 38:24","journal-title":"J Biomed Res"},{"key":"6232_CR40","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19361-0","volume":"11","author":"K Rust","year":"2020","unstructured":"Rust K et al (2020) A single-cell atlas and lineage analysis of the adult Drosophila ovary. Nat Commun 11:5628","journal-title":"Nat Commun"},{"key":"6232_CR41","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1091\/mbc.e09-01-0089","volume":"21","author":"L Lewellyn","year":"2010","unstructured":"Lewellyn L, Dumont J, Desai A, Oegema K (2010) Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Mol Biol Cell 21:50\u201362","journal-title":"Mol Biol Cell"},{"key":"6232_CR42","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1111\/j.1749-6632.1990.tb21669.x","volume":"582","author":"TE Schroeder","year":"1990","unstructured":"Schroeder TE (1990) The contractile ring and furrowing in dividing cells. Ann N Y Acad Sci 582:78\u201387","journal-title":"Ann N Y Acad Sci"},{"key":"6232_CR43","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.ceb.2012.10.012","volume":"25","author":"JA Schiel","year":"2013","unstructured":"Schiel JA, Prekeris R (2013) Membrane dynamics during cytokinesis. Curr Opin Cell Biol 25:92\u201398","journal-title":"Curr Opin Cell Biol"},{"key":"6232_CR44","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.semcdb.2016.06.010","volume":"59","author":"JA Brill","year":"2016","unstructured":"Brill JA, Yildirim S, Fabian L (2016) Phosphoinositide signaling in sperm development. Semin Cell Dev Biol 59:2\u20139","journal-title":"Semin Cell Dev Biol"},{"key":"6232_CR45","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.devcel.2005.02.010","volume":"8","author":"C Janetopoulos","year":"2005","unstructured":"Janetopoulos C, Borleis J, Vazquez F, Iijima M, Devreotes P (2005) Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis. Dev Cell 8:467\u2013477","journal-title":"Dev Cell"},{"key":"6232_CR46","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1146\/annurev.physiol.65.092101.142517","volume":"65","author":"HL Yin","year":"2003","unstructured":"Yin HL, Janmey PA (2003) Phosphoinositide regulation of the actin cytoskeleton. Annu Rev Physiol 65:761\u2013789","journal-title":"Annu Rev Physiol"},{"key":"6232_CR47","doi-asserted-by":"publisher","first-page":"R930","DOI":"10.1016\/j.cub.2011.10.001","volume":"21","author":"JA Brill","year":"2011","unstructured":"Brill JA, Wong R, Wilde A (2011) Phosphoinositide function in cytokinesis. Curr Biol 21:R930\u2013R934","journal-title":"Curr Biol"},{"key":"6232_CR48","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1016\/j.cub.2005.06.060","volume":"15","author":"R Wong","year":"2005","unstructured":"Wong R et al (2005) PIP2 hydrolysis and calcium release are required for cytokinesis in Drosophila spermatocytes. Curr Biol 15:1401\u20131406","journal-title":"Curr Biol"},{"key":"6232_CR49","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.devcel.2006.04.021","volume":"11","author":"TD Resnick","year":"2006","unstructured":"Resnick TD et al (2006) INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the shugoshin MEI-S332 in Drosophila. Dev Cell 11:57\u201368","journal-title":"Dev Cell"},{"key":"6232_CR50","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1101\/gad.12.3.396","volume":"12","author":"MG Giansanti","year":"1998","unstructured":"Giansanti MG et al (1998) Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis. Genes Dev 12:396\u2013410","journal-title":"Genes Dev"},{"key":"6232_CR51","unstructured":"Yang S.-M., Cao C.-D., Di Y. & Wang M.-J. D-bifunctional protein deficiency caused by HSD17B4 gene mutation in a neonate. Chin J Contemp Pediatr 23, 1058"},{"key":"6232_CR52","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1016\/j.cub.2008.08.061","volume":"18","author":"E Szafer-Glusman","year":"2008","unstructured":"Szafer-Glusman E et al (2008) A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytes. Curr Biol 18:1426\u20131431","journal-title":"Curr Biol"},{"key":"6232_CR53","doi-asserted-by":"publisher","first-page":"13108","DOI":"10.1093\/nar\/gkab1187","volume":"49","author":"W Fan","year":"2021","unstructured":"Fan W et al (2021) FARS2 deficiency in Drosophila reveals the developmental delay and seizure manifested by aberrant mitochondrial tRNA metabolism. Nucleic Acids Res 49:13108\u201313121","journal-title":"Nucleic Acids Res"},{"key":"6232_CR54","doi-asserted-by":"crossref","unstructured":"Housden BE, Lin S, Perrimon N (2014) Cas9-Based Genome Editing in Drosophila. Methods in Enzymology, vol 546. Elsevier, pp 415\u2013439","DOI":"10.1016\/B978-0-12-801185-0.00019-2"},{"key":"6232_CR55","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1534\/genetics.113.160713","volume":"196","author":"SJ Gratz","year":"2014","unstructured":"Gratz SJ et al (2014) Highly specific and efficient CRISPR\/Cas9-catalyzed homology-directed repair in Drosophila. Genetics 196:961\u2013971","journal-title":"Genetics"},{"key":"6232_CR56","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.4918","volume":"14","author":"G Kunduri","year":"2024","unstructured":"Kunduri G, Acharya J (2024) Live imaging and analysis of meiotic cytokinesis in Drosophila testes. BIO-PROTOCOL 14:e4918","journal-title":"BIO-PROTOCOL"},{"key":"6232_CR57","volume":"83","author":"P Sitaram","year":"2014","unstructured":"Sitaram P, Hainline SG, Lee LA (2014) Cytological analysis of spermatogenesis: live and fixed preparations of Drosophila testes. J Vis Exp 83:e51058","journal-title":"J Vis Exp"},{"key":"6232_CR58","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.cmet.2020.06.016","volume":"32","author":"J-W Song","year":"2020","unstructured":"Song J-W et al (2020) Omics-driven systems interrogation of metabolic dysregulation in COVID-19 pathogenesis. Cell Metab 32:188-202.e5","journal-title":"Cell Metab"},{"key":"6232_CR59","doi-asserted-by":"publisher","DOI":"10.34133\/research.0006","volume":"2022","author":"H Miao","year":"2022","unstructured":"Miao H et al (2022) Lipidome atlas of the developing heart uncovers dynamic membrane lipid attributes underlying cardiac structural and metabolic maturation. Research 2022:0006","journal-title":"Research"},{"key":"6232_CR60","doi-asserted-by":"publisher","first-page":"2720","DOI":"10.1016\/j.celrep.2019.02.015","volume":"26","author":"B Li","year":"2019","unstructured":"Li B et al (2019) Microbiota depletion impairs thermogenesis of brown adipose tissue and browning of white adipose tissue. Cell Rep 26:2720-2737e.e5","journal-title":"Cell Rep"},{"key":"6232_CR61","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/s42255-021-00425-4","volume":"3","author":"SM Lam","year":"2021","unstructured":"Lam SM et al (2021) A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19. Nat Metab 3:909\u2013922","journal-title":"Nat Metab"},{"key":"6232_CR62","doi-asserted-by":"publisher","DOI":"10.1039\/B913353D","volume":"6","author":"G Shui","year":"2010","unstructured":"Shui G et al (2010) Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics. Mol Biosyst 6:1008","journal-title":"Mol Biosyst"},{"key":"6232_CR63","doi-asserted-by":"publisher","first-page":"4357","DOI":"10.1016\/j.chroma.2011.05.011","volume":"1218","author":"G Shui","year":"2011","unstructured":"Shui G et al (2011) Derivatization-independent cholesterol analysis in crude lipid extracts by liquid chromatography\/mass spectrometry: applications to a rabbit model for atherosclerosis. J Chromatogr A 1218:4357\u20134365","journal-title":"J Chromatogr A"},{"key":"6232_CR64","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","volume":"29","author":"A Dobin","year":"2013","unstructured":"Dobin A et al (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29:15\u201321","journal-title":"Bioinformatics"}],"container-title":["Cellular and Molecular Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00018-026-06232-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-026-06232-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00018-026-06232-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T02:02:45Z","timestamp":1785808965000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00018-026-06232-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,1]]},"references-count":64,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["6232"],"URL":"https:\/\/doi.org\/10.1007\/s00018-026-06232-y","relation":{},"ISSN":["1420-9071"],"issn-type":[{"value":"1420-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,1]]},"assertion":[{"value":"7 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"292"}}