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Informed consent was obtained from all patients. Animal studies were approved by the Shanghai Yishang Biotechnology Center.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","label":"Declaration of competing interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"370"}}