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Ethics approval (SH9H-2019-TK101-1) was granted by the Human Research Ethics Committee of Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine in accordance with the Declaration of Helsinki. Written informed consent was obtained from all patients. C57BL\/6 mice were purchased from Shanghai Jihui Laboratory Animal Care Co.,Ltd. The procedures for inducing mouse skin fibrosis were performed in accordance with the Guide for the Care and Use of Laboratory Animals (NRC 2011) and were approved by the Committee on the Ethics of Animal Experiments of Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine (SH9H-2019A302-1).","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"365"}}