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Therefore, the aim of this retrospective cross-sectional study was to assess a\u00a0possible association between craniofacial patterns and TMA in German orthodontic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients undergoing orthodontic treatment with dental records including anamnesis, pretreatment lateral cephalograms and orthopantomograms were evaluated. Cephalometric analyses were conducted digitally and lines, angles and proportions were measured to investigate craniofacial morphology. Skeletal classes were determined by the individualised Wits appraisal and ANB angle. The TMA was identified with the help of orthopantomograms. Patients showing agenesis of at least one third molar were included in the TMA group. Statistical analysis was performed to assess the association between TMA and craniofacial patterns (\u03b1\u00a0of\n                      <jats:italic>p<\/jats:italic>\n                      \u202f\u2264\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A\u00a0total of 148\u00a0patients were included, 40 (27.0%) presented at least one missing tooth (TMA group) and 108 (73.0%) showed full dentition (control group). Skeletal class determined by the individualised Wits appraisal revealed statistical significance between the TMA and control groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u20090.022), in which TMA patients were 11\u00a0times more likely to present with an individualised skeletal class\u00a0III (odds ratio 11.3, 95% confidence interval 1.7\u2013139.5). Skeletal cephalometric analysis revealed no statistical differences between TMA and control groups for any further angular, linear and proportional parameters.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Third molar agenesis was associated with skeletal class\u00a0III determined by the individualised Wits appraisal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00056-023-00484-0","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T01:02:07Z","timestamp":1687914127000},"page":"120-126","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Association between craniofacial patterns and third molar agenesis in orthodontic patients","Zusammenhang zwischen kraniofazialen Mustern und Aplasie der dritten Molaren bei kieferorthop\u00e4dischen Patienten"],"prefix":"10.1007","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8207-5257","authenticated-orcid":false,"given":"Eva","family":"Paddenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9931-0935","authenticated-orcid":false,"given":"Alice Correa","family":"Silva-Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0724-9776","authenticated-orcid":false,"given":"Ariane Beatriz","family":"Blancato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4372-9718","authenticated-orcid":false,"given":"C\u00e9sar Penazzo","family":"Lepri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1137-5361","authenticated-orcid":false,"given":"Peter","family":"Proff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5351-2526","authenticated-orcid":false,"given":"Erika Calvano","family":"K\u00fcchler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9473-8724","authenticated-orcid":false,"given":"Christian","family":"Kirschneck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"key":"484_CR1","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1177\/0022034515581644","volume":"94","author":"K Carter","year":"2015","unstructured":"Carter\u00a0K, Worthington\u00a0S (2015) Morphologic and demographic predictors of third molar agenesis: a systematic review and meta-analysis. 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This research project was approved by the local Ethics Committee of the University of Regensburg (number 19-1549-101). Informed consent was obtained from all individual participants included in the study, and parental\/guardian consent was also obtained from all patients younger than 18 years at the time of dental examination.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}