{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T23:13:35Z","timestamp":1779318815925,"version":"3.51.4"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003105","name":"Universidade Federal De Uberl\u00e2ndia","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003105","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Orofac Orthop"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the association between tooth agenesis and root morphology alterations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective observational study initially analyzed 27,707 medical records of patients from radiological centers in southeastern Brazil. After applying the inclusion and exclusion criteria, 1193\u00a0sets of periapical radiographs of maxillary incisors were selected from eligible patients aged between 8\u00a0and 30\u00a0years. The root morphology of the upper incisors was classified into five categories: normal, short, blunt, apically bent, or pipette-shaped, based on criteria established in the literature. In addition, missing teeth were recorded applying the tooth agenesis code (TAC). Two previously calibrated specialists analyzed the radiographs visually. Logistic regression with odds ratios (OR) estimated the associations between tooth agenesis and root alterations at a\u00a05% significance level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients with any form of tooth agenesis were more likely to have pipette-shaped (i.e., roots with a\u00a0narrow cervical third and gradual tapering toward the apex; OR\u202f=\u20097.04; 95% confidence interval [CI] 4.23\u201311.72) or blunt (OR\u202f=\u20095.31; 95% CI 2.62\u201310.75) roots. Conversely, the agenesis group showed a\u00a0significantly lower prevalence of normal roots than the group without agenesis (OR\u202f=\u20090.12; 95% CI 0.07\u20130.20).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Root morphology alterations are strongly associated with tooth agenesis. This knowledge should be used for customized approaches and multidisciplinary strategies to minimize complications and improve treatment in this group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00056-025-00639-1","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T11:27:16Z","timestamp":1771241236000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between tooth agenesis and root morphology assessed by periapical radiographs","Assoziation zwischen Zahnagenesie und Wurzelmorphologie, evaluiert anhand periapikaler R\u00f6ntgenaufnahmen"],"prefix":"10.1007","author":[{"given":"Guilherme Henrique","family":"Borges","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabela","family":"Vinhal Henriques","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walbert","family":"de Andrade Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rubens","family":"Spin-Neto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Renato","family":"Paranhos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,16]]},"reference":[{"issue":"1","key":"639_CR1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/s10266-021-00634-z","volume":"110","author":"R Baba","year":"2022","unstructured":"Baba\u00a0R, Sato\u00a0A, Arai\u00a0K (2022) Consecutive tooth agenesis patterns in non-syndromic oligodontia. 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Borges, I. Vinhal Henriques, W. de Andrade Vieira, R. Spin-Neto and L. Paranhos declare that there are no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study received approval from the research ethics committee of a higher education institution (number 6.976.142).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}},{"value":"Written informed consent to participate was not obtained, as this retrospective study exclusively used secondary data derived from pre-existing diagnostic radiographic examinations and medical records. All data were fully anonymized, with no access to personally identifiable, clinical, biometric, or sensitive information, and no direct contact with participants occurred.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Written Informed Consent to Participate"}}]}}