{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:29:41Z","timestamp":1792456181630,"version":"4.5.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum W\u00fcrzburg"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Orofac Orthop"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Oral health-related quality of life (OHRQoL) is a\u00a0patient-reported outcome measure (PROM) that assesses patients\u2019 subjective perception of their oral health status. Previous studies assessing the influence of malocclusions on OHRQoL revealed inconsistent results. This cross-sectional multicenter cohort study aimed to investigate the impact of general orthodontic treatment need (OTN) and of specific anterior malocclusions on OHRQoL and its subdomains in children and adolescents with class\u00a0II malocclusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 321 patients with class\u00a0II malocclusion who required an initial orthodontic diagnosis. OHRQoL was assessed using the German version of the Child Oral Health Impact Profile (COHIP-G19). OTN was evaluated using the Dental Aesthetic Index (DAI) and the Index of Orthodontic Treatment Need (IOTN). To determine specific anterior malocclusions, overjet, overbite, anterior crowding, and anterior spacing were analyzed. Multiple linear regression analysis was performed to examine the effects of OTN and of the anterior malocclusions on OHRQoL and its subdomains, adjusted for demographic confounders (age, gender, and socioeconomic status).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>High values for OTN were significantly associated with poorer OHRQoL in patients with class\u00a0II malocclusion. Multiple regression showed a\u00a0significant effect of overjet and anterior crowding in the upper jaw on OHRQoL. No statistically significant associations were found between OHRQoL and anterior open bite, deep bite, or anterior spacing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>High general OTN as well as specific anterior malocclusions such as increased overjet and anterior crowding showed significant associations with OHRQoL in children and adolescents with class\u00a0II malocclusion. In addition, other unmeasured factors likely play a\u00a0distinctive role in determining OHRQoL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00056-026-00663-9","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T12:29:16Z","timestamp":1779798556000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Influence of general orthodontic treatment need and of specific anterior malocclusions on oral health-related quality of life in children and adolescents with class\u00a0II malocclusion","Einfluss des allgemeinen kieferorthop\u00e4dischen Behandlungsbedarfs und spezifischer Frontzahnfehlstellungen auf die mundgesundheitsbezogene Lebensqualit\u00e4t bei Kindern und Jugendlichen mit Klasse-II-Dysgnathie"],"prefix":"10.1007","author":[{"given":"Stefan","family":"Ke\u00df","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noah Frieder","family":"Nordblom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Geim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Stellzig-Eisenhauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"663_CR1","doi-asserted-by":"publisher","first-page":"766","DOI":"10.3109\/09638288.2012.707746","volume":"35","author":"EL Bamm","year":"2013","unstructured":"Bamm\u00a0EL, Rosenbaum\u00a0P, Wilkins\u00a0S (2013) Is Health Related Quality Of Life of people living with chronic conditions related to patient satisfaction with care? 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