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It is characterized by left or biventricular dilation and a\u00a0reduced systolic function. The causes are manifold and range from myocarditis to alcohol and other toxins, to rheumatological, endocrinological, and metabolic diseases. Peripartum cardiomyopathy is a\u00a0special form that occurs at the end of or shortly after pregnancy. Genetic mutations can be detected in approximately 30\u201350% of DCM patients. Owing to the growing possibilities of genetic diagnostics, increasingly more triggering variants and hereditary mechanisms emerge. This is particularly important with regard to risk stratification for patients with variants with an increased risk of arrhythmias. Patient prognosis is determined by the occurrence of heart failure and arrhythmias. In addition to the treatment of the underlying disease or the elimination of triggering harmful toxins, therapy consists in guideline-directed heart failure treatment including drug and device therapy.<\/jats:p>","DOI":"10.1007\/s00059-020-04903-5","type":"journal-article","created":{"date-parts":[[2020,2,27]],"date-time":"2020-02-27T07:03:00Z","timestamp":1582786980000},"page":"212-220","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Dilated cardiomyopathies and non-compaction cardiomyopathy","Dilatative Kardiomyopathien und Non-compaction-Kardiomyopathie"],"prefix":"10.1007","volume":"45","author":[{"given":"A.","family":"H\u00e4nselmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Veltmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Bauersachs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Berliner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,27]]},"reference":[{"issue":"7","key":"4903_CR1","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1161\/CIRCRESAHA.117.311812","volume":"121","author":"E Braunwald","year":"2017","unstructured":"Braunwald\u00a0E (2017) Cardiomyopathies: an overview. 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C.\u00a0Veltmann received honoraria from the following companies and\/or is a member of their advisory boards: Abbott, Boston Scientific, Biotronik, Medtronic, CVRx, Daiichi Sankyo, Bayer, Boehringer Ingelheim, BMS, Zoll. J.\u00a0Bauersachs: Related to the present work: None. Unrelated to the present work: Honoraria for lectures and\/or consulting: Novartis, BMS, Pfizer, Vifor, Bayer, Servier, Daichii, CVRx, MSD, Boehringer Ingelheim, AstraZeneca, Abiomed, Abbott, Medtronic; Research support: Zoll, CVRx, Bayer, Vifor, Abiomed, Medtronic. D.\u00a0Berliner received honoraria and\/or travel support from the following companies and\/or is a member of their advisory boards: Novartis, Abbott, Daiichi Sankyo, Bayer and Boehringer Ingelheim.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this article no studies with human participants or animals were performed by any of the authors. All studies performed were in accordance with the ethical standards indicated in each case.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}