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This study aimed to investigate the disease and mortality burdens attributed to PM<jats:sub>2.5<\/jats:sub> in Germany in 2019.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Data from the Global Burden of Disease (GBD) Study 2019 were used to investigate disability-adjusted life\u2013years (DALYs), years of life lost (YLLs), years lived with disability (YLDs), and deaths attributed to ambient PM<jats:sub>2.5<\/jats:sub> pollution in Germany.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>In 2019, ambient PM<jats:sub>2.5<\/jats:sub> pollution in Germany was associated with significant health impacts, contributing to 27,040 deaths (2.82% of total deaths), 568,784 DALYs (2.09% of total DALYs), 135,725 YLDs (1.09% of total YLDs), and 433,058 YLLs (2.92% of total YLLs). The analysis further revealed that cardiometabolic and respiratory conditions, such as ischemic heart disease, stroke, chronic obstructive pulmonary disease, lung cancer, and diabetes mellitus, were the leading causes of mortality and disease burden associated with ambient PM<jats:sub>2.5<\/jats:sub> pollution in Germany from 1990\u20132019. Comparative assessments between 1990 and 2019 underscored ambient PM<jats:sub>2.5<\/jats:sub> as a\u00a0consistent prominent risk factor, ranking closely with traditional factors like smoking, arterial hypertension, and alcohol use contributing to deaths, DALYs, YLDs, and YLLs.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Ambient PM<jats:sub>2.5<\/jats:sub> pollution is one of the major health risk factors contributing significantly to the burden of disease and mortality in Germany, emphasizing the urgent need for targeted interventions to address its substantial contribution to chronic NCDs.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00059-024-05269-8","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T07:02:21Z","timestamp":1725951741000},"page":"42-50","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Burden of disease in Germany attributed to ambient particulate matter pollution","Krankheitslast in Deutschland durch Feinstaubbelastung"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7823-7671","authenticated-orcid":false,"given":"Omar","family":"Hahad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos","family":"Lelieveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadeer","family":"Al-Kindi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker H.","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Hobohm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"R\u00f6\u00f6sli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marin","family":"Kuntic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Daiber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,10]]},"reference":[{"issue":"9859","key":"5269_CR1","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1016\/S0140-6736(12)61728-0","volume":"380","author":"R Lozano","year":"2012","unstructured":"Lozano\u00a0R, Naghavi\u00a0M, Foreman\u00a0K, Lim\u00a0S, Shibuya\u00a0K, Aboyans\u00a0V et\u00a0al (2012) Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a\u00a0systematic analysis for the Global Burden of Disease Study 2010. 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All studies mentioned were in accordance with the ethical standards indicated in each case.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}