{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T15:14:04Z","timestamp":1784992444510,"version":"3.55.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2013,6,29]],"date-time":"2013-06-29T00:00:00Z","timestamp":1372464000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Neuroradiol"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1007\/s00062-013-0231-0","type":"journal-article","created":{"date-parts":[[2013,6,28]],"date-time":"2013-06-28T01:47:09Z","timestamp":1372384029000},"page":"111-119","source":"Crossref","is-referenced-by-count":15,"title":["Cerebral Magnetic Resonance Imaging Findings in Adults with Haemolytic Uraemic Syndrome Following an Infection with Escherichia coli, Subtype O104:H4"],"prefix":"10.1007","volume":"24","author":[{"given":"U.","family":"L\u00f6bel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Eckert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Simova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Meier-Cillien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kluge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Gerloff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"R\u00f6ther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Magnus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Fiehler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,6,29]]},"reference":[{"issue":"9","key":"231_CR1","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1001\/archpedi.1980.02130210053014","volume":"134","author":"JF Bale Jr.","year":"1980","unstructured":"Bale JF Jr., Brasher C, Siegler RL. CNS manifestations of the haemolytic uraemic syndrome. Relationship to metabolic alterations and prognosis. Am J Dis Child. 1980;134(9):869\u201372.","journal-title":"Am J Dis Child"},{"issue":"5","key":"231_CR2","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1136\/adc.84.5.434","volume":"84","author":"KJ Eriksson","year":"2001","unstructured":"Eriksson KJ, Boyd SG, Tasker RC. Acute neurology and neurophysiology of haemolytic uraemic syndrome. Arch Dis Child. 2001;84(5):434\u20135.","journal-title":"Arch Dis Child"},{"issue":"1","key":"231_CR3","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1002\/ana.410190120","volume":"19","author":"KJ Sheth","year":"1986","unstructured":"Sheth KJ, Swick HM, Haworth N. Neurological involvement in haemolytic uraemic syndrome. Ann Neurol. 1986;19(1):90\u20133.","journal-title":"Ann Neurol"},{"issue":"4","key":"231_CR4","doi-asserted-by":"crossref","first-page":"734","DOI":"10.3174\/ajnr.A2351","volume":"32","author":"TN Ellchuk","year":"2011","unstructured":"Ellchuk TN, Shah LM, Hewlett RH, Osborn AG. Suspicious neuroimaging pattern of thrombotic micro-angiopathy. AJNR Am J Neuroradiol. 2011;32(4):734\u20138.","journal-title":"Am J Neuroradiol"},{"issue":"7","key":"231_CR5","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.2215\/CJN.08921209","volume":"5","author":"S Nathanson","year":"2010","unstructured":"Nathanson S, Kwon T, Elmaleh M, Charbit M, Launay EA, Harambat J, et al. Acute neurological involvement in diarrhoea-associated haemolytic uraemic syndrome. Clin J Am Soc Nephrol. 2010;5(7):1218\u201328.","journal-title":"Clin J Am Soc Nephrol"},{"issue":"6","key":"231_CR6","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1093\/brain\/aws090","volume":"135","author":"T Magnus","year":"2012","unstructured":"Magnus T, Rother J, Simova O, Meier-Cillien M, Repenthin J, Moller F, et al. The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak. Brain. 2012;135(6):1850\u20139.","journal-title":"Brain"},{"issue":"8","key":"231_CR7","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s00431-002-0988-7","volume":"161","author":"F Ahrens","year":"2002","unstructured":"Ahrens F, Ludwig K, Terstegge K, Querfeld U. Encephalopathy and exposure to Shiga toxin without evidence of haemolytic uraemic syndrome. Eur J Pediatr. 2002;161(8):462\u20133.","journal-title":"Eur J Pediatr"},{"key":"231_CR8","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.brainres.2007.05.067","volume":"1161","author":"J Goldstein","year":"2007","unstructured":"Goldstein J, Loidl CF, Creydt VP, Boccoli J, Ibarra C. Intracerebroventricular administration of Shiga toxin type 2 induces striatal neuronal death and glial alterations: an ultrastructural study. Brain Res. 2007;1161:106\u201315.","journal-title":"Brain Res"},{"issue":"2","key":"231_CR9","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1111\/j.1552-6569.2008.00279.x","volume":"21","author":"JC Garcia-Monco","year":"2011","unstructured":"Garcia-Monco JC, Cortina IE, Ferreira E, Martinez A, Ruiz L, Cabrera A, et al. Reversible splenial lesion syndrome (RESLES): what\u2019s in a name? J Neuroimaging. 2011;21(2):e1\u201314.","journal-title":"J Neuroimaging"},{"issue":"6","key":"231_CR10","first-page":"1144","volume":"19","author":"H Ogura","year":"1998","unstructured":"Ogura H, Takaoka M, Kishi M, Kimoto M, Shimazu T, Yoshioka T, et al. Reversible MR findings of haemolytic uraemic syndrome with mild encephalopathy. AJNR Am J Neuroradiol. 1998;19(6):1144\u20135.","journal-title":"Am J Neuroradiol"},{"issue":"10","key":"231_CR11","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s00247-004-1289-2","volume":"34","author":"M Steinborn","year":"2004","unstructured":"Steinborn M, Leiz S, Rudisser K, Griebel M, Harder T, Hahn H. CT and MRI in haemolytic uraemic syndrome with central nervous system involvement: distribution of lesions and prognostic value of imaging findings. Pediatr Radiol. 2004;34(10):805\u201310.","journal-title":"Pediatr Radiol"},{"issue":"1","key":"231_CR12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1552-6569.2003.tb00160.x","volume":"13","author":"H Nakamura","year":"2003","unstructured":"Nakamura H, Takaba H, Inoue T, Saku Y, Saito F, Ibayashi S, \u00adet al. MRI findings of haemolytic uraemic syndrome with encephalopathy: widespread symmetrical distribution. J Neuroimaging. 2003;13(1):75\u20138.","journal-title":"J Neuroimaging"},{"key":"231_CR13","doi-asserted-by":"crossref","unstructured":"Meuth SG, Gobel K, Kanyshkova T, Ehling P, Ritter MA, Schwindt W, et al. Thalamic involvement in patients with neurologic impairment due to Shiga toxin 2. Ann Neurol. 2013;73(3):419\u201329. doi:10.1002\/ana.23814.","DOI":"10.1002\/ana.23814"},{"key":"231_CR14","doi-asserted-by":"crossref","unstructured":"Wengenroth M, Hoeltje J, Repenthin J, Meyer TN, Bonk F, Becker H, et al. Central nervous system involvement in adults with epidemic haemolytic uraemic syndrome. AJNR Am J Neuroradiol. 2013;34(5):1016\u201321. doi:10.3174\/ajnr.A3336.","DOI":"10.3174\/ajnr.A3336"},{"key":"231_CR15","doi-asserted-by":"crossref","unstructured":"Weissenborn K, Donnerstag F, Kielstein JT, Heeren M, Worthmann H, Hecker H, et al. Neurologic manifestations of E coli infection-induced haemolytic uraemic syndrome in adults. Neurology. 2012;79(14):1466\u201373. doi:10.1212\/WNL.0b013e31826d5f26.","DOI":"10.1212\/WNL.0b013e31826d5f26"},{"issue":"1","key":"231_CR16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF00858990","volume":"9","author":"EG Gallo","year":"1995","unstructured":"Gallo EG, Gianantonio CA. Extrarenal involvement in diarrhoea-associated haemolytic uraemic syndrome. Pediatr Nephrol. 1995;9(1):117\u20139.","journal-title":"Pediatr Nephrol"},{"issue":"2","key":"231_CR17","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0887-8994(94)00121-H","volume":"12","author":"ND Barnett","year":"1995","unstructured":"Barnett ND, Kaplan AM, Bernes SM, Cohen ML. Haemolytic uraemic syndrome with particular involvement of basal ganglia and favourable outcome. Pediatr Neurol. 1995;12(2):155\u20138.","journal-title":"Pediatr Neurol"},{"issue":"7","key":"231_CR18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s002340100557","volume":"43","author":"S Schmidt","year":"2001","unstructured":"Schmidt S, Gudinchet F, Meagher-Villemure K, Maeder P. Brain involvement in haemolytic uraemic syndrome: MRI features of coagulative necrosis. Neuroradiology. 2001;43(7):581\u20135.","journal-title":"Neuroradiology"},{"issue":"5","key":"231_CR19","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1651-2227.1993.tb12721.x","volume":"82","author":"S Hamano","year":"1993","unstructured":"Hamano S. Neurological manifestation of haemorrhagic colitis in the outbreak of Escherichia coli O157:H7 infection in Japan. Acta Paedatr. 1993;82(5):454\u20138.","journal-title":"Acta Paedatr"},{"issue":"36","key":"231_CR20","first-page":"A2314","volume":"97","author":"H Karch","year":"2000","unstructured":"Karch H, Bockem\u00fchl J, Huppertz H-I. Erkrankungen durch enteroh\u00e4morrhagische Escherichia coli (EHEC). Dtsch Arztebl. 2000;97(36):A2314\u201338.","journal-title":"Dtsch Arztebl"},{"key":"231_CR21","first-page":"183","volume-title":"Escherichia Coli O157: H7 and other Shiga Toxin-producing E. Coli strains","author":"H Karch","year":"1998","unstructured":"Karch H, Schmidt H, Brunder W. Plasmid-encoded determinants of Escherichia coli O157:H7. In: Kaper JB, O\u2019Brian AD, editors. Escherichia Coli O157: H7 and other Shiga Toxin-producing E. Coli strains. Washington, D.C.: American Society for Microbiology; 1998. pp.\u00a0183\u201394."},{"issue":"3","key":"231_CR22","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0022-3476(83)80661-1","volume":"102","author":"BT Steele","year":"1983","unstructured":"Steele BT, Murphy N, Chuang SH, McGreal D, Arbus GS. Recovery from prolonged coma in haemolytic uraemic syndrome.\u00adJ Pediatr. 1983;102(3):402\u20134.","journal-title":"J Pediatr"},{"issue":"8","key":"231_CR23","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/BF02012739","volume":"24","author":"YK Jeong","year":"1994","unstructured":"Jeong YK, Kim IO, Kim WS, Hwang YS, Choi Y, Yeon KM. Haemolytic uraemic syndrome: MR findings of CNS complications. Pediatr Radiol. 1994;24(8):585\u20136.","journal-title":"Pediatr Radiol"},{"issue":"5","key":"231_CR24","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.3174\/ajnr.A0965","volume":"29","author":"MD Vergouwen","year":"2008","unstructured":"Vergouwen MD, Adriani KS, Roos YB, Groothoff JW, Majoie CB. Proximal cerebral artery stenosis in a patient with haemolytic uraemic syndrome. AJNR Am J Neuroradiol. 2008;29(5):e34.","journal-title":"Am J Neuroradiol"},{"issue":"3","key":"231_CR25","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s004010050423","volume":"91","author":"M Mizuguchi","year":"1996","unstructured":"Mizuguchi M, Tanaka S, Fujii I, Tanizawa H, Suzuki Y, Igarashi T, et al. Neuronal and vascular pathology produced by verocytotoxin 2 in the rabbit central nervous system. Acta neuropathologica. 1996;91(3):254\u201362.","journal-title":"Acta neuropathologica"}],"container-title":["Clinical Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-013-0231-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00062-013-0231-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-013-0231-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T22:23:03Z","timestamp":1558563783000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00062-013-0231-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,29]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["231"],"URL":"https:\/\/doi.org\/10.1007\/s00062-013-0231-0","relation":{},"ISSN":["1869-1439","1869-1447"],"issn-type":[{"value":"1869-1439","type":"print"},{"value":"1869-1447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,29]]}}}