{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T13:21:02Z","timestamp":1768915262206,"version":"3.49.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T00:00:00Z","timestamp":1541376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Neuroradiol"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s00062-018-0738-5","type":"journal-article","created":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T08:58:46Z","timestamp":1541408326000},"page":"137-144","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Arterial Spin Labeling and Central Precocious Puberty"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0537-6483","authenticated-orcid":false,"given":"Julien","family":"Denis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volodia","family":"Dangouloff-Ros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graziella","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Flechtner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Piketty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinane","family":"Samara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Levy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Gr\u00e9vent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Elodie","family":"Millischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Brunelle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Prevot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Polak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Boddaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,11,5]]},"reference":[{"key":"738_CR1","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1542\/peds.2008-0146","volume":"123","author":"RL Rosenfield","year":"2009","unstructured":"Rosenfield RL, Lipton RB, Drum ML. Thelarche, pubarche, and menarche attainment in children with normal and elevated body mass index. Pediatrics. 2009;123:84\u20138.","journal-title":"Pediatrics"},{"key":"738_CR2","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1056\/NEJMcp0800459","volume":"358","author":"J-C Carel","year":"2008","unstructured":"Carel JC, L\u00e9ger J. Clinical practice. Precocious puberty. N Engl J Med. 2008;358:2366\u201377.","journal-title":"N. Engl. J. Med."},{"key":"738_CR3","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/S2213-8587(15)00380-0","volume":"4","author":"AC Latronico","year":"2016","unstructured":"Latronico AC, Brito VN, Carel JC. Causes, diagnosis, and treatment of central precocious puberty. Lancet Diabetes Endocrinol. 2016;4:265\u201374.","journal-title":"Lancet Diabetes Endocrinol"},{"key":"738_CR4","doi-asserted-by":"publisher","first-page":"e752","DOI":"10.1542\/peds.2008-1783","volume":"123","author":"J-C Carel","year":"2009","unstructured":"Carel JC, Eugster EA, Rogol A, Ghizzoni L, Palmert MR; ESPE-LWPES GnRH Analogs Consensus Conference Group, Antoniazzi F, Berenbaum S, Bourguignon JP, Chrousos GP, Coste J, Deal S, de Vries L, Foster C, Heger S, Holland J, Jahnukainen K, Juul A, Kaplowitz P, Lahlou N, Lee MM, Lee P, Merke DP, Neely EK, Oostdijk W, Phillip M, Rosenfield RL, Shulman D, Styne D, Tauber M, Wit JM. Consensus statement on the use of gonadotropin-releasing hormone analogs in children. Pediatrics. 2009;123:e752\u2013e62.","journal-title":"Pediatrics"},{"key":"738_CR5","doi-asserted-by":"publisher","first-page":"3644","DOI":"10.1210\/jc.2003-031532","volume":"89","author":"P Kaplowitz","year":"2004","unstructured":"Kaplowitz P. Clinical characteristics of 104 children referred for evaluation of precocious puberty. J\u00a0Clin Endocrinol Metab. 2004;89:3644\u201350.","journal-title":"J Clin Endocrinol Metab"},{"key":"738_CR6","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/S0022-3476(95)70254-7","volume":"127","author":"EK Neely","year":"1995","unstructured":"Neely EK, Hintz RL, Wilson DM, Lee PA, Gautier T, Argente J, Stene M. Normal ranges for immunochemiluminometric gonadotropin assays. J\u00a0Pediatr. 1995;127:40\u20136.","journal-title":"J Pediatr"},{"key":"738_CR7","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1148\/radiology.208.2.9680569","volume":"208","author":"DC Alsop","year":"1998","unstructured":"Alsop DC, Detre JA. Multisection cerebral blood flow MR imaging with continuous arterial spin labeling. Radiology. 1998;208:410\u20136.","journal-title":"Radiology"},{"key":"738_CR8","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.3174\/ajnr.A1030","volume":"29","author":"AR Deibler","year":"2008","unstructured":"Deibler AR, Pollock JM, Kraft RA, Tan H, Burdette JH, Maldjian JA. Arterial spin-labeling in routine clinical practice, part 1: technique and artifacts. AJNR Am J Neuroradiol. 2008;29:1228\u201334.","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"738_CR9","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1148\/radiol.2016150789","volume":"281","author":"S Haller","year":"2016","unstructured":"Haller S, Zaharchuk G, Thomas DL, Lovblad KO, Barkhof F, Golay X. Arterial spin labeling perfusion of the brain: emerging clinical applications. Radiology. 2016;281:337\u201356.","journal-title":"Radiology"},{"key":"738_CR10","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1097\/00004647-199701000-00009","volume":"17","author":"RB Buxton","year":"1997","unstructured":"Buxton RB, Frank LR. A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. J\u00a0Cereb Blood Flow Metab. 1997;17:64\u201372.","journal-title":"J Cereb Blood Flow Metab"},{"key":"738_CR11","doi-asserted-by":"publisher","first-page":"5509","DOI":"10.1210\/en.2009-0584","volume":"150","author":"P Ciofi","year":"2009","unstructured":"Ciofi P, Garret M, Lapirot O, Lafon P, Loyens A, Pr\u00e9vot V, Levine JE. Brain-endocrine interactions: a\u00a0microvascular route in the mediobasal hypothalamus. Endocrinology. 2009;150:5509\u201319.","journal-title":"Endocrinology"},{"key":"738_CR12","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1038\/nrendo.2016.193","volume":"13","author":"P Tissier Le","year":"2017","unstructured":"Le Tissier P, Campos P, Lafont C, Roman\u00f2 N, Hodson DJ, Mollard P. An updated view of hypothalamic-vascular-pituitary unit function and plasticity. Nat Rev Endocrinol. 2017;13:257\u201367.","journal-title":"Nat Rev Endocrinol"},{"key":"738_CR13","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3174\/ajnr.A3670","volume":"35","author":"KW Yeom","year":"2014","unstructured":"Yeom KW, Mitchell LA, Lober RM, Barnes PD, Vogel H, Fisher PG, Edwards MS. Arterial spin-labeled perfusion of pediatric brain tumors. AJNR Am J Neuroradiol. 2014;35:395\u2013401.","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"738_CR14","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-195909000-00030","volume-title":"Radiographic atlas of skeletal development of the hand and wrist","author":"WW Greulich","year":"1959","unstructured":"Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist. Stanford: Stanford University Press; 1959."},{"key":"738_CR15","doi-asserted-by":"publisher","first-page":"196","DOI":"10.6065\/apem.2013.18.4.196","volume":"18","author":"DS Lee","year":"2013","unstructured":"Lee DS, Ryoo NY, Lee SH, Kim S, Kim JH. Basal luteinizing hormone and follicular stimulating hormone: is it sufficient for the diagnosis of precocious puberty in girls? Ann Pediatr Endocrinol Metab. 2013;18:196\u2013201.","journal-title":"Ann Pediatr Endocrinol Metab"},{"key":"738_CR16","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1210\/jcem-71-5-1251","volume":"71","author":"KE Oerter","year":"1990","unstructured":"Oerter KE, Uriarte MM, Rose SR, Barnes KM, Cutler GB Jr. Gonadotropin secretory dynamics during puberty in normal girls and boys. J\u00a0Clin Endocrinol Metab. 1990;71:1251\u20138.","journal-title":"J Clin Endocrinol Metab"},{"key":"738_CR17","doi-asserted-by":"publisher","first-page":"3940","DOI":"10.1093\/bioinformatics\/bti623","volume":"21","author":"T Sing","year":"2005","unstructured":"Sing T, Sander O, Beerenwinkel N, Lengauer T. ROCR: visualizing classifier performance in R. Bioinformatics. 2005;21:3940\u20131.","journal-title":"Bioinformatics"},{"key":"738_CR18","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.2214\/ajr.162.5.8166005","volume":"162","author":"MJ Sharafuddin","year":"1994","unstructured":"Sharafuddin MJ, Luisiri A, Garibaldi LR, Fulk DL, Klein JB, Gillespie KN, Graviss ER. MR imaging diagnosis of central precocious puberty: importance of changes in the shape and size of the pituitary gland. AJR Am J Roentgenol. 1994;162:1167\u201373.","journal-title":"AJR Am. J. Roentgenol."},{"key":"738_CR19","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1210\/jc.2010-2745","volume":"96","author":"SS Mogensen","year":"2011","unstructured":"Mogensen SS, Aksglaede L, Mouritsen A, S\u00f8rensen K, Main KM, Gideon P, Juul A. Diagnostic work-up of 449 consecutive girls who were referred to be evaluated for precocious puberty. J\u00a0Clin Endocrinol Metab. 2011;96:1393\u2013401.","journal-title":"J Clin Endocrinol Metab"},{"key":"738_CR20","doi-asserted-by":"publisher","first-page":"e104108","DOI":"10.1371\/journal.pone.0104108","volume":"9","author":"HJMM Mutsaerts","year":"2014","unstructured":"Mutsaerts HJ, Steketee RM, Heijtel DF, Kuijer JP, van Osch MJ, Majoie CB, Smits M, Nederveen AJ. Inter-vendor reproducibility of pseudo-continuous arterial spin labeling at 3\u202fT. PLoS ONE. 2014;9:e104108.","journal-title":"PLoS ONE"},{"key":"738_CR21","doi-asserted-by":"publisher","first-page":"4465","DOI":"10.1073\/pnas.0902599107","volume":"107","author":"C Lafont","year":"2010","unstructured":"Lafont C, Desarm\u00e9nien MG, Cassou M, Molino F, Lecoq J, Hodson D, Lacampagne A, Mennessier G, El Yandouzi T, Carmignac D, Fontanaud P, Christian H, Coutry N, Fernandez-Fuente M, Charpak S, Le Tissier P, Robinson IC, Mollard P. Cellular in vivo imaging reveals coordinated regulation of pituitary microcirculation and GH cell network function. Proc Natl Acad Sci U S\u00a0A. 2010;107:4465\u201370.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"738_CR22","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/j.1365-2826.2007.01576.x","volume":"19","author":"M Baroncini","year":"2007","unstructured":"Baroncini M, Allet C, Leroy D, Beauvillain JC, Francke JP, Prevot V. Morphological evidence for direct interaction between gonadotrophin-releasing hormone neurones and astroglial cells in the human hypothalamus. J\u00a0Neuroendocrinol. 2007;19:691\u2013702.","journal-title":"J Neuroendocrinol"},{"key":"738_CR23","doi-asserted-by":"publisher","first-page":"e1001808","DOI":"10.1371\/journal.pbio.1001808","volume":"12","author":"P Giacobini","year":"2014","unstructured":"Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, Langlet F, Hobo B, Cagnoni G, Gallet S, Hanchate NK, Mazur D, Taniguchi M, Mazzone M, Verhaagen J, Ciofi P, Bouret SG, Tamagnone L, Prevot V. Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A. PLoS Biol. 2014;12:e1001808.","journal-title":"PLoS Biol."},{"key":"738_CR24","doi-asserted-by":"publisher","first-page":"6385","DOI":"10.1038\/ncomms7385","volume":"6","author":"J Parkash","year":"2015","unstructured":"Parkash J, Messina A, Langlet F, Cimino I, Loyens A, Mazur D, Gallet S, Balland E, Malone SA, Pralong F, Cagnoni G, Schellino R, De Marchis S, Mazzone M, Pasterkamp RJ, Tamagnone L, Prevot V, Giacobini P. Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence. Nat Commun. 2015;6:6385.","journal-title":"Nat Commun"},{"key":"738_CR25","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/j.neuroimage.2009.11.074","volume":"50","author":"M Baroncini","year":"2010","unstructured":"Baroncini M, Jissendi P, Catteau-Jonard S, Dewailly D, Pruvo JP, Francke JP, Prevot V. Sex steroid hormones-related structural plasticity in the human hypothalamus. Neuroimage. 2010;50:428\u201333.","journal-title":"Neuroimage"},{"key":"738_CR26","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1056\/NEJMcp1109290","volume":"366","author":"MR Palmert","year":"2012","unstructured":"Palmert MR, Dunkel L. Clinical practice. Delayed puberty. N Engl J Med. 2012;366:443\u201353.","journal-title":"N. Engl. J. Med."},{"key":"738_CR27","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1159\/000362414","volume":"82","author":"T Kuiri-H\u00e4nninen","year":"2014","unstructured":"Kuiri-H\u00e4nninen T, Sankilampi U, Dunkel L. Activation of the hypothalamic-pituitary-gonadal axis in infancy: minipuberty. Horm Res Paediatr. 2014;82:73\u201380.","journal-title":"Horm Res Paediatr"},{"key":"738_CR28","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1038\/nn.4298","volume":"19","author":"A Messina","year":"2016","unstructured":"Messina A, Langlet F, Chachlaki K, Roa J, Rasika S, Jouy N, Gallet S, Gaytan F, Parkash J, Tena-Sempere M, Giacobini P, Prevot V. A microRNA switch regulates the rise in hypothalamic GnRH production before puberty. Nat Neurosci. 2016;19:835\u201344.","journal-title":"Nat Neurosci"},{"key":"738_CR29","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1002\/mrm.25197","volume":"73","author":"DC Alsop","year":"2015","unstructured":"Alsop DC, Detre JA, Golay X, G\u00fcnther M, Hendrikse J, Hernandez-Garcia L, Lu H, MacIntosh BJ, Parkes LM, Smits M, van Osch MJ, Wang DJ, Wong EC, Zaharchuk G. Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: a consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med. 2015;73:102\u201316.","journal-title":"Magn Reson Med"},{"key":"738_CR30","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1038\/jcbfm.2014.109","volume":"34","author":"DJ Hodkinson","year":"2014","unstructured":"Hodkinson DJ, O\u2019Daly O, Zunszain PA, Pariante CM, Lazurenko V, Zelaya FO, Howard MA, Williams SC. Circadian and homeostatic modulation of functional connectivity and regional cerebral blood flow in humans under normal entrained conditions. J\u00a0Cereb Blood Flow Metab. 2014;34:1493\u20139.","journal-title":"J Cereb Blood Flow Metab"},{"key":"738_CR31","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.cmet.2013.03.004","volume":"17","author":"F Langlet","year":"2013","unstructured":"Langlet F, Levin BE, Luquet S, Mazzone M, Messina A, Dunn-Meynell AA, Balland E, Lacombe A, Mazur D, Carmeliet P, Bouret SG, Prevot V, Dehouck B. Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting. Cell Metab. 2013;17:607\u201317.","journal-title":"Cell Metab"}],"container-title":["Clinical Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-018-0738-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00062-018-0738-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-018-0738-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T10:05:37Z","timestamp":1584612337000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00062-018-0738-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,5]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["738"],"URL":"https:\/\/doi.org\/10.1007\/s00062-018-0738-5","relation":{},"ISSN":["1869-1439","1869-1447"],"issn-type":[{"value":"1869-1439","type":"print"},{"value":"1869-1447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,5]]},"assertion":[{"value":"22 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"J.\u00a0Denis, V.\u00a0Dangouloff-Ros, G.\u00a0Pinto, I.\u00a0Flechtner, M.\u00a0Piketty, D.\u00a0Samara, R.\u00a0Levy, D.\u00a0Gr\u00e9vent, A.-E.\u00a0Millischer, F.\u00a0Brunelle, V.\u00a0Prevot, M.\u00a0Polak and N.\u00a0Boddaert declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}