{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:55:44Z","timestamp":1756385744482},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Neuroradiol"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1007\/s00062-019-00849-2","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T16:18:39Z","timestamp":1573229919000},"page":"797-804","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Freiburg Neuropathology Case Conference"],"prefix":"10.1007","volume":"29","author":[{"given":"C. A.","family":"Taschner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Doostkam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. C.","family":"Reinacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Urbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Prinz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"849_CR1","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1007\/s00415-014-7482-9","volume":"262","author":"R Hebel","year":"2015","unstructured":"Hebel\u00a0R, Dubaniewicz-Wybieralska\u00a0M, Dubaniewicz\u00a0A. Overview of neurosarcoidosis: recent advances. J\u00a0Neurol. 2015;262:258\u201367.","journal-title":"J Neurol"},{"key":"849_CR2","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4103\/2156-7514.80373","volume":"1","author":"DT Ginat","year":"2011","unstructured":"Ginat\u00a0DT, Dhillon\u00a0G, Almast\u00a0J. Magnetic resonance imaging of neurosarcoidosis. J\u00a0Clin Imaging Sci. 2011;1:15.","journal-title":"J Clin Imaging Sci"},{"key":"849_CR3","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.3174\/ajnr.A2089","volume":"31","author":"DF Black","year":"2010","unstructured":"Black\u00a0DF, Aksamit\u00a0AJ, Morris\u00a0JM. MR imaging of central nervous system Whipple disease: a\u00a015-year review. AJNR Am J Neuroradiol. 2010;31:1493\u20137.","journal-title":"AJNR Am J Neuroradiol"},{"key":"849_CR4","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.radonc.2016.12.033","volume":"122","author":"MN Kerbauy","year":"2017","unstructured":"Kerbauy\u00a0MN, Moraes\u00a0FY, Lok\u00a0BH, Ma\u00a0J, Kerbauy\u00a0LN, Spratt\u00a0DE, et al. Challenges and opportunities in primary CNS lymphoma: a systematic review. Radiother Oncol. 2017;122:352\u201361.","journal-title":"Radiother Oncol"},{"key":"849_CR5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1470-7330-14-22","volume":"14","author":"A Mansour","year":"2014","unstructured":"Mansour\u00a0A, Qandeel\u00a0M, Abdel-Razeq\u00a0H, Abu Ali\u00a0HA. MR imaging features of intracranial primary CNS lymphoma in immune competent patients. Cancer Imaging. 2014;14:22.","journal-title":"Cancer Imaging"},{"key":"849_CR6","first-page":"427","volume":"19","author":"RL Williams","year":"1998","unstructured":"Williams\u00a0RL, Meltzer\u00a0CC, Smirniotopoulos\u00a0JG, Fukui\u00a0MB, Inman\u00a0M. Cerebral MR imaging in intravascular lymphomatosis. AJNR Am J Neuroradiol. 1998;19:427\u201331.","journal-title":"AJNR Am J Neuroradiol"},{"key":"849_CR7","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1007\/s00234-002-0808-9","volume":"44","author":"N Martin-Duverneuil","year":"2002","unstructured":"Martin-Duverneuil\u00a0N, Mokhtari\u00a0K, Behin\u00a0A, Lafitte\u00a0F, Hoang-Xuan\u00a0K, Chiras\u00a0J. Intravascular malignant lymphomatosis. Neuroradiology. 2002;44:749\u201354.","journal-title":"Neuroradiology"},{"key":"849_CR8","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s00062-017-0589-5","volume":"27","author":"CA Taschner","year":"2017","unstructured":"Taschner\u00a0CA, S\u00fc\u00df\u00a0P, Sajonz\u00a0B, Urbach\u00a0H, Simon-Gabriel\u00a0CP, Prinz\u00a0M. Freiburg Neuropathology Case Conference : widespread white matter lesions in a\u00a0patient with progressive paraparesis and cortical blindness. Clin Neuroradiol. 2017;27:245\u201350.","journal-title":"Clin Neuroradiol"},{"key":"849_CR9","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s00062-017-0614-8","volume":"27","author":"CA Taschner","year":"2017","unstructured":"Taschner\u00a0CA, Doostkam\u00a0S, Shah\u00a0JM, Urbach\u00a0H, J\u00e4ger\u00a0M, Prinz\u00a0M. Freiburg Neuropathology Case Conference: cystic posterior fossa tumor. Clin Neuroradiol. 2017;27:393\u20138.","journal-title":"Clin Neuroradiol"},{"key":"849_CR10","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1177\/1756285608101222","volume":"2","author":"U Schlegel","year":"2009","unstructured":"Schlegel\u00a0U. Primary CNS lymphoma. Ther Adv Neurol Disord. 2009;2:93\u2013104.","journal-title":"Ther Adv Neurol Disord"},{"key":"849_CR11","volume-title":"WHO classification of tumours of the central nervous system","author":"DN Louis","year":"2016","unstructured":"Louis\u00a0DN, et\u00a0al. WHO classification of tumours of the central nervous system. 4th\u00a0ed. 2016.","edition":"4"},{"key":"849_CR12","first-page":"419","volume":"115","author":"L Von Baumgarten","year":"2018","unstructured":"Von Baumgarten\u00a0L, Illerhaus\u00a0G, Korfel\u00a0A, Schlegel\u00a0U, Deckert\u00a0M, Dreyling\u00a0M. The diagnosis and treatment of primary CNS lymphoma\u2014an interdisciplinary challenge. Dtsch \u00c4rztebl Int. 2018;115:419\u201326.","journal-title":"Dtsch \u00c4rztebl Int"},{"key":"849_CR13","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1038\/nrneurol.2013.83","volume":"9","author":"A Korfel","year":"2013","unstructured":"Korfel\u00a0A, Schlegel\u00a0U. Diagnosis and treatment of primary CNS lymphoma. Nat Rev Neurol. 2013;9:317\u201327.","journal-title":"Nat Rev Neurol"},{"key":"849_CR14","doi-asserted-by":"publisher","first-page":"e322","DOI":"10.1016\/S1470-2045(15)00076-5","volume":"16","author":"K Hoang-Xuan","year":"2015","unstructured":"Hoang-Xuan\u00a0K, Bessell\u00a0E, Bromberg\u00a0J, Hottinger\u00a0AF, Preusser\u00a0M, Rud\u00e0\u00a0R, et al. Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology. Lancet Oncol. 2015;16:e322\u201332.","journal-title":"Lancet Oncol"},{"key":"849_CR15","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1002\/hon.2087","volume":"32","author":"M Deckert","year":"2014","unstructured":"Deckert\u00a0M, Brunn\u00a0A, Montesinos-Rongen\u00a0M, Terreni\u00a0MR, Ponzoni\u00a0M. Primary lymphoma of the central nervous system\u2014a diagnostic challenge. Hematol Oncol. 2014;32:57\u201367.","journal-title":"Hematol Oncol"},{"key":"849_CR16","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","volume":"131","author":"DN Louis","year":"2016","unstructured":"Louis\u00a0DN, Perry\u00a0A, Reifenberger\u00a0G, von Deimling\u00a0A, Figarella-Branger\u00a0D, Cavenee\u00a0WK, et al. The 2016 world health organization classification of tumors of the central nervous system: a\u00a0summary. Acta Neuropathol. 2016;131:803\u201320.","journal-title":"Acta Neuropathol"},{"key":"849_CR17","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1215\/S1522851705000323","volume":"8","author":"S Hoffman","year":"2006","unstructured":"Hoffman\u00a0S, Propp\u00a0JM, McCarthy\u00a0BJ. Temporal trends in incidence of primary brain tumors in the United States, 1985\u20131999. Neuro Oncol. 2006;8:27\u201337.","journal-title":"Neuro Oncol"},{"key":"849_CR18","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1111\/bjh.14073","volume":"174","author":"MS Shiels","year":"2016","unstructured":"Shiels\u00a0MS, Pfeiffer\u00a0RM, Besson\u00a0C, Clarke\u00a0CA, Morton\u00a0LM, Nogueira\u00a0L, et al. Trends in primary central nervous system lymphoma incidence and survival in the U.S. Br J Haematol. 2016;174:417\u201324.","journal-title":"Br J Haematol"},{"key":"849_CR19","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1093\/neuonc\/nox187","volume":"20","author":"JS Mendez","year":"2018","unstructured":"Mendez\u00a0JS, Ostrom\u00a0QT, Gittleman\u00a0H, Kruchko\u00a0C, DeAngelis\u00a0LM, Barnholtz-Sloan\u00a0JS, et al. The elderly left behind\u2014changes in survival trends of primary central nervous system lymphoma over the past four decades. Neuro Oncol. 2018;20:687\u201394.","journal-title":"Neuro Oncol"},{"key":"849_CR20","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1038\/leu.2011.169","volume":"25","author":"M Deckert","year":"2011","unstructured":"Deckert\u00a0M, Engert\u00a0A, Br\u00fcck\u00a0W, Ferreri\u00a0AJ, Finke\u00a0J, Illerhaus\u00a0G, et al. Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma. Leukemia. 2011;25:1797\u2013807.","journal-title":"Leukemia"},{"key":"849_CR21","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1007\/s00292-013-1742-9","volume":"34","author":"W Br\u00fcck","year":"2013","unstructured":"Br\u00fcck W\u00a0 Brunn\u00a0A, Klapper\u00a0W, Kuhlmann\u00a0T, Metz\u00a0I, Paulus\u00a0W, et al. Differential diagnosis of lymphoid infiltrates in the central nervous system: experience of the network lymphomas and Lymphomatoid lesions in the nervous system. Pathologe. 2013;34:186\u201397.","journal-title":"Pathologe"},{"key":"849_CR22","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1200\/JCO.2003.09.139","volume":"21","author":"AJ Ferreri","year":"2003","unstructured":"Ferreri\u00a0AJ, Blay\u00a0JY, Reni\u00a0M, Pasini\u00a0F, Spina\u00a0M, Ambrosetti\u00a0A, et al. Prognostic scoring system for primary CNS lymphomas: the international extranodal lymphoma study group experience. J\u00a0Clin Oncol. 2003;21:266\u201372.","journal-title":"J Clin Oncol"}],"container-title":["Clinical Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-019-00849-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00062-019-00849-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-019-00849-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T00:05:55Z","timestamp":1604707555000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00062-019-00849-2"}},"subtitle":["A\u00a0Progressive Lesion of the Optic Tract, Brainstem, Hypothalamus and Basal Ganglia"],"short-title":[],"issued":{"date-parts":[[2019,11,8]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["849"],"URL":"https:\/\/doi.org\/10.1007\/s00062-019-00849-2","relation":{},"ISSN":["1869-1439","1869-1447"],"issn-type":[{"value":"1869-1439","type":"print"},{"value":"1869-1447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,8]]},"assertion":[{"value":"8 November 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical guidelines"}},{"value":"C.A.\u00a0Taschner, S.\u00a0Doostkam, P.C.\u00a0Reinacher, H.\u00a0Urbach, A.\u00a0Rau and M.\u00a0Prinz declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All investigations described in this manuscript were carried out with the approval of the responsible ethics committee and in accordance with national law and the Helsinki Declaration of 1975 (in its current revised form). Informed consent was obtained from the patient in this case if identifiable from images or other information within the manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}