{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T08:27:40Z","timestamp":1791534460383,"version":"4.3.4"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T00:00:00Z","timestamp":1669939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T00:00:00Z","timestamp":1669939200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Medizinische Fakult\u00e4t Heidelberg der Universit\u00e4t Heidelberg"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Neuroradiol"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Endovascular stroke treatment (EST) is commonly performed for acute basilar artery occlusion (BAO). We aimed to identify the role of the exact location of BAO in patients receiving EST regarding the stroke etiology, recanalization success and prediction of favorable clinical outcome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Retrospective analysis of 191 consecutive patients treated for BAO with EST from 01\/2013 until 06\/2021 in a\u00a0tertiary stroke center. Groups were defined according to exact location of BAO in\u00a0I: proximal third, II: middle third, III: distal third and IV: tip of the basilar artery. Univariate and multivariate analyses were performed for BAO location comparing stroke etiology, recanalization result and favorable clinical outcome according to mRS 0\u20133 90\u00a0days after stroke onset.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Occlusion sides types\u00a0I\u2013IV were evenly distributed (37, 36, 60\u00a0and 58\u00a0patients). Types\u00a0I and\u00a0II were more often associated with large artery atherosclerosis (50\u00a0vs. 10\u00a0patients, <jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001). Distal\/tip occlusion (types\u00a0III\/IV) occurred mostly in cardiac embolism or embolic stroke of unknown source (89\u00a0vs. 12\u00a0in types\u00a0I\/II, <jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001). Occlusion site correlated with the underlying stroke etiology (AUC [Area under the curve] 0.89, <jats:italic>p<\/jats:italic>\u202f&lt;\u20090.0001, OR [odds ratio] for embolism in type\u00a0IV: 245). Recanalization rates were higher in patients with distal occlusions (type\u00a0III\/IV OR 3.76, CI [95% confidence interval] 1.51\u20139.53, <jats:italic>p<\/jats:italic>\u202f=\u20090.0076). The BAO site is not predicting favorable clinical outcome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The exact basilar artery occlusion site in patients eligible for endovascular stroke treatment reflects the stroke etiology and is associated with differing recanalization success but does not predict favorable clinical outcome.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00062-022-01236-0","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T10:27:11Z","timestamp":1669976831000},"page":"483-490","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Exact Basilar Artery Occlusion Location Indicates Stroke Etiology and Recanalization Success in Patients Eligible for Endovascular Stroke Treatment"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2101-823X","authenticated-orcid":false,"given":"Matthias A.","family":"Mutke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9206-2636","authenticated-orcid":false,"given":"Arne","family":"Potreck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2509-5459","authenticated-orcid":false,"given":"Niclas","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6072-0438","authenticated-orcid":false,"given":"Fatih","family":"Seker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5473-8671","authenticated-orcid":false,"given":"Peter A.","family":"Ringleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2471-6647","authenticated-orcid":false,"given":"Simon","family":"Nagel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5075-704X","authenticated-orcid":false,"given":"Markus A.","family":"M\u00f6hlenbruch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9094-6769","authenticated-orcid":false,"given":"Martin","family":"Bendszus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1374-7854","authenticated-orcid":false,"given":"Charlotte S.","family":"Weyland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1236-8828","authenticated-orcid":false,"given":"Jessica","family":"Jesser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,2]]},"reference":[{"issue":"12","key":"1236_CR1","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1136\/neurintsurg-2018-014516","volume":"11","author":"TR Meinel","year":"2019","unstructured":"Meinel\u00a0TR, Kaesmacher\u00a0J, Chaloulos-Iakovidis\u00a0P, Panos\u00a0L, Mordasini\u00a0P, Mosimann\u00a0PJ, Michel\u00a0P, Hajdu\u00a0S, Ribo\u00a0M, Requena\u00a0M, Maegerlein\u00a0C, Friedrich\u00a0B, Costalat\u00a0V, Benali\u00a0A, Pierot\u00a0L, Gawlitza\u00a0M, Schaafsma\u00a0J, Pereira\u00a0VM, Gralla\u00a0J, Fischer\u00a0U. 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Neurosurgery. 2020;87:982\u201391.","journal-title":"Neurosurgery"}],"container-title":["Clinical Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-022-01236-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00062-022-01236-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-022-01236-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T17:03:35Z","timestamp":1685120615000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00062-022-01236-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["1236"],"URL":"https:\/\/doi.org\/10.1007\/s00062-022-01236-0","relation":{},"ISSN":["1869-1439","1869-1447"],"issn-type":[{"value":"1869-1439","type":"print"},{"value":"1869-1447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,2]]},"assertion":[{"value":"23 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"M.A.\u00a0Mutke, A.\u00a0Potreck, N.\u00a0Schmitt, P.A.\u00a0Ringleb, F.\u00a0Seker, C.S.\u00a0Weyland and J.\u00a0Jesser declare that they have no competing interests. S.\u00a0Nagel has no related disclosures, unrelated disclosures: consultancy: Brainomix, Boehringer Ingelheim; payment for lectures including service on speakers bureaus: Pfizer, Medtronic, Bayer AG. M.A.\u00a0M\u00f6hlenbruch has no related disclosures, unrelated disclosures: board membership: Codman; consultancy: Medtronic, MicroVention, Stryker; Grants\/Grants Pending: Balt*, MicroVention*; payment for lectures including service on speakers bureaus: Medtronic, MicroVention, Stryker; *money paid to the institution. M.\u00a0Bendszus has not related disclosures, unrelated disclosures: grants and personal fees from Bayer, Codman, Guerbet, Medtronic and Novartis; grants from the German Research Council (DFG), European Union, Hopp Foundation, Siemens, and Stryker; personal fees from BBraun, B\u00f6hringer Ingelheim, Roche, Teva, and Vascular Dynamics.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the local ethics committee (Ethikkommission der Universit\u00e4t Heidelberg). Informed consent was waived due to the retrospective nature of this study. The study was conducted following the STROBE criteria.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}