{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:00:52Z","timestamp":1740171652433,"version":"3.37.3"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012681","name":"Universit\u00e4tsklinikum K\u00f6ln","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012681","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Neuroradiol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The WEB\u00a017 system represents the fifth generation of Woven Endobridge (WEB) flow disruptors and features a\u00a0low profile with fewer wires than its predecessor, the WEB\u00a021. The present study compares the safety and efficacy of the WEB\u00a017 and WEB\u00a021 for the treatment of unruptured cerebral aneurysms with 4\u20137\u202fmm device sizes, which were available for both systems.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patient and aneurysm characteristics, complications, clinical outcome and angiographic results were retrospectively analysed. 1:1 propensity score matching was performed to adjust for minor baseline differences between the groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty aneurysms treated with WEB\u00a021 and 90\u00a0with WEB\u00a017 were included. The overall failure rate (deployment failure and adjunctive stent) was significantly higher with WEB\u00a021 (16.7%) than with WEB\u00a017 (3.3%, <jats:italic>p<\/jats:italic>\u202f&lt;\u20090.01). The rates of neurological events between WEB\u00a021 (6.7%) and WEB 17\u00a0treatment (1.1%) were not significantly different (<jats:italic>p<\/jats:italic>\u202f=\u20090.08). Also, procedural morbidity was comparably low in both groups (WEB\u00a021: 3.3%, WEB\u00a017: 0%, <jats:italic>p<\/jats:italic>\u202f=\u20090.16). The rates of complete\/adequate occlusion at follow up were 69.7%\/86.4% for WEB\u00a017 vs. 80.4%\/91.3% for WEB\u00a021 at short-term (<jats:italic>p<\/jats:italic>\u202f=\u20090.27), and 64.5%\/83.9% vs. 75.9%\/86.2% at mid-term (<jats:italic>p<\/jats:italic>\u202f=\u20090.41), respectively. Propensity score matching confirmed the results of the unmatched series.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>WEB\u00a017 and WEB\u00a021 had\u00a0a\u00a0similar safety and efficacy profile, but WEB\u00a017 was associated with an improved feasibility. Prospective studies with long-term follow-up will define the full potential of the WEB\u00a017 system.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00062-024-01430-2","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T11:01:52Z","timestamp":1718794912000},"page":"841-850","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Propensity Score-matched Comparison of WEB\u00a017 and WEB\u00a021 with 4\u20137\u202fmm Device Sizes for the Treatment of Unruptured Intracranial Aneurysms"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2620-7611","authenticated-orcid":false,"given":"Lukas","family":"Goertz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Liebig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eberhard","family":"Siebert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Zopfs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lenhard","family":"Pennig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Schlamann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Radomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Dorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Kabbasch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"1430_CR1","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1136\/neurintsurg-2021-018414","volume":"15","author":"L Pierot","year":"2023","unstructured":"Pierot\u00a0L, Szikora\u00a0I, Barreau\u00a0X, et\u00a0al. Aneurysm treatment with the Woven EndoBridge (WEB) device in the combined population of two prospective, multicenter series: 5\u2011year follow-up. J\u00a0NeuroIntervent Surg. 2023;15:552\u20137.","journal-title":"J NeuroIntervent Surg"},{"key":"1430_CR2","doi-asserted-by":"publisher","first-page":"211","DOI":"10.5469\/neuroint.2021.00395","volume":"16","author":"L Pierot","year":"2021","unstructured":"Pierot\u00a0L. Ten years of clinical evaluation of the woven endobridge: a\u00a0safe and effective treatment for wide-neck bifurcation aneurysms. Neurointervention. 2021;16:211\u201321.","journal-title":"Neurointervention"},{"key":"1430_CR3","doi-asserted-by":"publisher","first-page":"922","DOI":"10.3174\/ajnr.A4230","volume":"36","author":"L Pierot","year":"2015","unstructured":"Pierot\u00a0L, Moret\u00a0J, Turjman\u00a0F, et\u00a0al. WEB treatment of intracranial aneurysms: feasibility, complications, and 1\u2011month safety results with the WEB DL and WEB SL\/SLS in the French Observatory. AJNR Am J Neuroradiol. 2015;36:922\u20137.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1430_CR4","doi-asserted-by":"crossref","unstructured":"Spelle L, Costalat V, Caroff J, et\u00a0al. CLinical EValuation of WEB 17 device in intracranial aneuRysms (CLEVER): procedural, 30-day and 1\u2011year safety results for ruptured and unruptured aneurysms. J\u00a0NeuroIntervent Surg. 2023;.","DOI":"10.1136\/jnis-2023-020866"},{"key":"1430_CR5","doi-asserted-by":"publisher","first-page":"467","DOI":"10.3174\/ajnr.A7830","volume":"44","author":"P Pagano","year":"2023","unstructured":"Pagano\u00a0P, Cortese\u00a0J. Aneurysm treatment with woven endobridge-17: angiographic and clinical results at 12 months from a\u00a0retrospective, 2\u2011center series. AJNR Am J Neuroradiol. 2023;44:467\u201373.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1430_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/s00062-020-00946-7","author":"I K\u00f6nig","year":"2020","unstructured":"K\u00f6nig\u00a0I, Maurer\u00a0C, Berlis\u00a0A, et\u00a0al. Treatment of ruptured and Unruptured Intracranial aneurysms with WEB 17 versus WEB 21 systems: comparison of indications and early angiographic outcomes. Clin Neuroradiol. 2020; https:\/\/doi.org\/10.1007\/s00062-020-00946-7.","journal-title":"Clin Neuroradiol."},{"key":"1430_CR7","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1136\/neurintsurg-2021-017876","volume":"14","author":"P Pagano","year":"2022","unstructured":"Pagano\u00a0P, Paiusan\u00a0L, Soize\u00a0S, et\u00a0al. Intracranial aneurysm treatment with intrasaccular flow disruption: comparison of WEB-21 and WEB-17 systems. J\u00a0NeuroIntervent Surg. 2022;14:904\u20139.","journal-title":"J NeuroIntervent Surg"},{"key":"1430_CR8","first-page":"1766","volume":"40","author":"L Goertz","year":"2019","unstructured":"Goertz\u00a0L, Liebig\u00a0T, Siebert\u00a0E, et\u00a0al. Low-profile intra-aneurysmal flow disruptor WEB 17 versus WEB predecessor systems for treatment of small intracranial aneurysms: comparative analysis of procedural safety and feasibility. AJNR Am J Neuroradiol. 2019;40:1766\u201372.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1430_CR9","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1136\/neurintsurg-2017-013448","volume":"10","author":"L Pierot","year":"2018","unstructured":"Pierot\u00a0L, Moret\u00a0J, Barreau\u00a0X, et\u00a0al. Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series. 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World Neurosurgery. 2021;146:e1326-e1334.","journal-title":"World Neurosurgery"}],"container-title":["Clinical Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-024-01430-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00062-024-01430-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00062-024-01430-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T17:03:21Z","timestamp":1731603801000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00062-024-01430-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,19]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["1430"],"URL":"https:\/\/doi.org\/10.1007\/s00062-024-01430-2","relation":{},"ISSN":["1869-1439","1869-1447"],"issn-type":[{"type":"print","value":"1869-1439"},{"type":"electronic","value":"1869-1447"}],"subject":[],"published":{"date-parts":[[2024,6,19]]},"assertion":[{"value":"5 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"CK serves as consultant for Acandis GmbH (Pforzheim, Germany) and as proctor for MicroVention Inc.\/Sequent Medical (Aliso Viejo, CA, USA). TL serves or previously served as proctor for MicroVention Inc.\/Sequent Medical, CERUS Endovascular (Fremont, CA, USA), Phenox (Bochum, Germany), Stryker (Kalamazoo, MI, USA), and Medtronic (Dublin, Ireland). FD serves as consultant\/ proctor for MicroVention Inc.\/Sequent Medical, Balt (Irvine, CA, USA), Cerenovus\/Johnson&Johnson (Irvine, CA, USA); received speakers honoraria from Cerenovus\/ Johnson&Johnson, Acandis, Asahi (Tokyo, Japan), Q\u2019Apel (Fremont, CA, USA), Penumbra (Alameda, CA, USA), Medtronic, Stryker; received scientific grants from Cerenovus\/ Johnson&Johnson. DZ is on the speaker\u2019s bureau of Philips (Amsterdam, the Netherlands) and lecturer for Amboss GmbH (Cologne, Germany). The other authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this article no studies with human participants or animals were performed by any of the authors. All studies mentioned were in accordance with the ethical standards indicated in each case. For images or other information within the manuscript which identify patients, consent was obtained from them and\/or their legal guardians.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}