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Clinical endpoints included National Institutes of Health Stroke Scale (NIHSS) scores and modified ranking scores (mRS), safety and efficacy endpoints included in-stent thrombosis and in-stent stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty-nine patients were included (pEGASUS-HPC,\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u200934; CREDO heal,\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u200935). Both groups showed significant improvement in arterial diameter post-intervention (pEGASUS-HPC: 0.47\u202fmm (SD 0.27\u202fmm) to 1.69\u202fmm (SD 0.55\u202fmm); CREDO heal: 0.57\u202fmm (SD 0.41\u202fmm) to 1.89\u202fmm (SD 0.62\u202fmm)). Revascularization success, defined as residual stenosis &lt;\u202f50%, was achieved in 32\/34 (93.9%) patients in the pEGASUS-HPC group and 33\/35 (94.3%) in the CREDO heal group. In-stent re-stenosis occurred in 5\/34 (14.7%) of patients in the pEGASUS-HPC group and 2\/35 (5.7%) in the CREDO heal group and retreatment with PTA was performed in 3\/34 (8.8%) and 2\/35 (5.7%), respectively. Peri- or postprocedural in-stent thrombosis occurred in 3\/34 (8.8%) of patients in the pEGASUS-HPC group and 2\/35 (5.7%) in the CREDO heal group. At 3\u20136\u00a0months, the proportion of patients achieving an mRS score of 0\u20132 was 25\/34 (73.5%) in the pEGASUS-HPC group and 28\/35 (80.0%) in the CREDO heal group (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u20090.578).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both stent systems proved effective and safe, showing significant post-intervention arterial dilation, high revascularization rates, and similar functional outcomes (mRS 0\u20132 at 3\u20136\u00a0months), though they differed in in-stent restenosis rates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00062-025-01544-1","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T23:00:29Z","timestamp":1754607629000},"page":"39-48","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of pEGASUS-HPC and CREDO Heal stent systems deployed via NeuroSpeed percutaneous angioplasty balloon catheter for treatment of acute symptomatic intracranial stenosis and occlusion"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2819-4623","authenticated-orcid":false,"given":"Abdallah","family":"Aburub","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Almohammad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Khanafer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakarya","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Gurschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yashar","family":"Aghazadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mete","family":"Dadak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tawfik","family":"Moher Alsady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Timmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Gerstner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayan Alhaj","family":"Moustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oussama","family":"Dob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Nimsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Sa\u00df","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Henkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Kemmling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,8]]},"reference":[{"key":"1544_CR1","doi-asserted-by":"publisher","first-page":"11S","DOI":"10.1111\/j.1552-6569.2009.00415.x","volume":"19","author":"MFK Suri","year":"2009","unstructured":"Suri MFK, Johnston SC. 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H.\u00a0Henkes: consulting and proctoring for WallabyPhenox GmbH, co-owner of CONTARA GmbH, A.\u00a0Khanafer: consulting and proctoring for WallabyPhenox GmbH, A. Kemmling: consulting and proctoring for WallabyPhenox GmbH.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki. Ethical approval for the study was provided by our local Ethics Committee (IRB: 24-180 RS).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}