{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:29:49Z","timestamp":1787840989885,"version":"build-2784847793"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Neuroradiol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Evaluation of the impact of Deep Learning Image Reconstruction (DLIR) compared to Adaptive Statistical Iterative Reconstruction-Veo (ASIR-V) on image quality and early ischemic changes detection on non-contrast computed tomography (NCCT) in stroke suspected patients. A\u00a0secondary objective was to determine the potential influence of reconstruction algorithm on ASPECT scoring relative to automated e-ASPECT score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients undergoing NCCT within 6 hours of symptom onset were retrospectively included. Images were reconstructed using ASIR-V and high-strength DLIR. Four readers with varying experience independently assessed subjective image quality, gray\u2013white matter differentiation, diagnostic confidence, presence of ischemic lesions and ASPECTS scoring. Diagnostic performance (accuracy, sensitivity, specificity) was calculated using e-ASPECTS as reference. Evaluation time was recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>DLIR significantly improved subjective image quality and gray\u2013white matter contrast compared with ASIR-V (odds ratios 2.96\u20133.96; p 0.001). Diagnostic performance for detecting early ischemic changes showed no significant difference, with similar accuracy, sensitivity and specificity. Evaluation time did not differ. A\u00a0trend toward higher specificity and reduced bias for ASPECTS \u22656 was observed with DLIR, but mixed-model analysis did not confirm statistical significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DLIR improves subjective image quality in acute stroke NCCT but does not significantly improve detection accuracy or ASPECTS scoring compared with ASIR-V. A\u00a0tendency toward improved specificity was observed; further studies with larger cohorts are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00062-026-01645-5","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T11:30:19Z","timestamp":1775734219000},"page":"941-951","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Performance of Deep Learning Reconstruction for Detection of Early Ischemic Changes in NCCT: Comparison with ASIR-V in Acute Stroke"],"prefix":"10.1007","volume":"36","author":[{"given":"Michal","family":"Pula","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Korbecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Winiarczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadiusz","family":"Kaca\u0142a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Litwinowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Sobanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julita","family":"Nadwodna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Zdanowicz-Ratajczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maciej","family":"Guzi\u0144ski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"key":"1645_CR1","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/S1474-4422(21)00252-0","volume":"20","author":"VL Feigin","year":"2021","unstructured":"Feigin VL, Stark BA, Johnson CO, et al. 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