{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T17:11:11Z","timestamp":1780333871874,"version":"3.54.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Klin Intensivmed Notfmed"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1007\/s00063-020-00723-x","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T12:05:50Z","timestamp":1599739550000},"page":"699-707","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Notf\u00e4lle in der Dermatologie","Emergencies in dermatology"],"prefix":"10.1007","volume":"115","author":[{"given":"Daniela Stefanie","family":"Neumayer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Rongisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"K\u00e4stle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,10]]},"reference":[{"issue":"12","key":"723_CR1","doi-asserted-by":"publisher","first-page":"e0143304","DOI":"10.1371\/journal.pone.0143304","volume":"10","author":"L Newman","year":"2015","unstructured":"Newman\u00a0L, Rowley\u00a0J, Vander Hoorn\u00a0S, Wijesooriya\u00a0NS, Unemo\u00a0M, Low\u00a0N et\u00a0al (2015) Global estimates of the prevalence and incidence of four curable sexually transmitted infections in 2012 based on systematic review and global reporting. PLoS ONE 10(12):e143304","journal-title":"PLoS ONE"},{"key":"723_CR2","volume-title":"Gonorrhea\u2014Annual Epidemiological Report 2017","author":"ECDC: European Centre for Disease Prevention and Control;","year":"2019","unstructured":"ECDC: European Centre for Disease Prevention and Control; (2019) Gonorrhea\u2014Annual Epidemiological Report 2017"},{"issue":"3","key":"723_CR3","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1128\/CMR.00010-14","volume":"27","author":"M Unemo","year":"2014","unstructured":"Unemo\u00a0M, Shafer\u00a0WM (2014) Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future. Clin Microbiol Rev 27(3):587\u2013613","journal-title":"Clin Microbiol Rev"},{"key":"723_CR4","unstructured":"Altmeyer\u2019s Enzyklop\u00e4die."},{"key":"723_CR5","unstructured":"Braun Falco\u2019s Dermatologie, Venerologie und Allergologie: Springer Verlag; 2018."},{"issue":"8067","key":"723_CR6","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/S0140-6736(78)90870-X","volume":"1","author":"D Barlow","year":"1978","unstructured":"Barlow\u00a0D, Phillips\u00a0I (1978) Gonorrhoea in women. Diagnostic, clinical, and laboratory aspects. Lancet 1(8067):761\u2013764","journal-title":"Lancet"},{"issue":"3","key":"723_CR7","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1093\/cid\/cix769","volume":"66","author":"J Reekie","year":"2018","unstructured":"Reekie\u00a0J, Donovan\u00a0B, Guy\u00a0R, Hocking\u00a0JS, Kaldor\u00a0JM, Mak\u00a0DB et al (2018) Risk of pelvic inflammatory disease in relation to Chlamydia and gonorrhea testing, repeat testing, and Positivity: a population-based cohort study. Clin Infect Dis 66(3):437\u2013443","journal-title":"Clin Infect Dis"},{"key":"723_CR8","unstructured":"AWMF (2019) S2-Leitlinie \u201eDiagnostik und Therapie der Gonorrhoe 2018. https:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/059-004l_S2k_Gonorrhoe-Diagnostik-Therapie_2019-03.pdf. Zugegriffen: Feb. 2020"},{"key":"723_CR9","unstructured":"Robert-Koch-Institut (2020) https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Merkblaetter\/Ratgeber_Chlamydiosen_Teil1.html#doc2382764bodyText6. Zugegriffen: Feb. 2020"},{"key":"723_CR10","unstructured":"AWMF (2016) S2k-Leitlinie \u201eInfektionen mit Chlamydia trachomatis 2016\u201c. https:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/059-005l_S2k_Chlamydia-trachomatis_Infektionen_2016-12.pdf. Zugegriffen: Feb. 2020"},{"key":"723_CR11","unstructured":"Leitfaden STI-Therapie und -Pr\u00e4vention der deutschen STI-Gesellschaft zur F\u00f6rderung der Sexuellen Gesundheit (DSTIG). 3.\u00a0Auflage ed2019\/2020."},{"issue":"1","key":"723_CR12","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s00105-016-3912-1","volume":"68","author":"W Pfutzner","year":"2017","unstructured":"Pfutzner\u00a0W (2017) Drug reactions. Hautarzt 68(1):4","journal-title":"Hautarzt"},{"issue":"1","key":"723_CR13","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00105-016-3908-x","volume":"68","author":"C Mobs","year":"2017","unstructured":"Mobs\u00a0C, Pfutzner\u00a0W (2017) Diagnostics of drug hypersensitivity reactions. Hautarzt 68(1):19\u201328","journal-title":"Hautarzt"},{"key":"723_CR14","volume-title":"Allergologie in Klinik und Praxis","author":"AJK-T Trautmann","year":"2013","unstructured":"Trautmann\u00a0AJK\u2011T (2013) Allergologie in Klinik und Praxis. Thieme, Stuttgart"},{"issue":"3","key":"723_CR15","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.jaci.2011.01.038","volume":"127","author":"FE Simons","year":"2011","unstructured":"Simons\u00a0FE, Ardusso\u00a0LR, Bilo\u00a0MB, El-Gamal\u00a0YM, Ledford\u00a0DK, Ring\u00a0J et al (2011) World Allergy Organization anaphylaxis guidelines: summary. J\u00a0Allergy Clin Immunol 127(3):587\u2013593e1\u201322","journal-title":"J Allergy Clin Immunol"},{"issue":"7","key":"723_CR16","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1111\/j.1365-2222.2011.03779.x","volume":"41","author":"JK Lee","year":"2011","unstructured":"Lee\u00a0JK, Vadas\u00a0P (2011) Anaphylaxis: mechanisms and management. Clin Exp Allergy 41(7):923\u2013938","journal-title":"Clin Exp Allergy"},{"key":"723_CR17","volume-title":"Angewandte Allergologie","author":"JBK Ring","year":"2004","unstructured":"Ring\u00a0JBK, Duda\u00a0D, Eschenhagen\u00a0T, Fuchs\u00a0Th, Huttegger\u00a0I et\u00a0al (2004) Angewandte Allergologie. Urban & Vogel, M\u00fcnchen"},{"key":"723_CR18","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1159\/000315935","volume":"95","author":"M Worm","year":"2010","unstructured":"Worm\u00a0M (2010) Epidemiology of anaphylaxis. Chem Immunol Allergy 95:12\u201321","journal-title":"Chem Immunol Allergy"},{"issue":"3","key":"723_CR19","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1007\/s40629-014-0009-1","volume":"23","author":"J Ring","year":"2014","unstructured":"Ring\u00a0J, Beyer\u00a0K, Biedermann\u00a0T, Bircher\u00a0A, Duda\u00a0D, Fischer\u00a0J et\u00a0al (2014) Guideline for acute therapy and management of anaphylaxis: S2 Guideline of the German Society for Allergology and Clinical Immunology. Allergo J Int 23(3):96\u2013112","journal-title":"Allergo J Int"},{"issue":"6","key":"723_CR20","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.jaad.2008.09.015","volume":"59","author":"D Gerson","year":"2008","unstructured":"Gerson\u00a0D, Sriganeshan\u00a0V, Alexis\u00a0JB (2008) Cutaneous drug eruptions: a\u00a05-year experience. J\u00a0Am Acad Dermatol 59(6):995\u2013999","journal-title":"J Am Acad Dermatol"},{"issue":"5","key":"723_CR21","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s00105-013-2696-9","volume":"65","author":"M Ziemer","year":"2014","unstructured":"Ziemer\u00a0M (2014) Delayed-type cutaneous drug reactions. Pathogenesis, clinical features and histology. Hautarzt 65(5):397\u2013408","journal-title":"Hautarzt"},{"issue":"1","key":"723_CR22","doi-asserted-by":"publisher","first-page":"96","DOI":"10.5414\/ALX01508E","volume":"1","author":"M Mockenhaupt","year":"2017","unstructured":"Mockenhaupt\u00a0M (2017) Epidemiology of cutaneous adverse drug reactions. Allergol Sel 1(1):96\u2013108","journal-title":"Allergol Sel"},{"issue":"1","key":"723_CR23","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s12016-017-8654-z","volume":"54","author":"M Lerch","year":"2018","unstructured":"Lerch\u00a0M, Mainetti\u00a0C, Terziroli Beretta-Piccoli\u00a0B, Harr\u00a0T (2018) Current perspectives on Stevens-Johnson syndrome and toxic epidermal necrolysis. Clin Rev Allergy Immunol 54(1):147\u2013176","journal-title":"Clin Rev Allergy Immunol"},{"issue":"5","key":"723_CR24","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1007\/s00105-018-4176-8","volume":"69","author":"M Mockenhaupt","year":"2018","unstructured":"Mockenhaupt\u00a0M (2018) Acute life-threatening drug reactions of the skin. Hautarzt 69(5):364\u2013375","journal-title":"Hautarzt"},{"issue":"5","key":"723_CR25","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1046\/j.1365-2133.2003.05323.x","volume":"148","author":"CM Dobson","year":"2003","unstructured":"Dobson\u00a0CM, King\u00a0CM (2003) Adult staphylococcal scalded skin syndrome: histological pitfalls and new diagnostic perspectives. Br J Dermatol 148(5):1068\u20131069","journal-title":"Br J Dermatol"},{"issue":"2","key":"723_CR26","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1046\/j.1523-1747.2000.00061.x","volume":"115","author":"S Bastuji-Garin","year":"2000","unstructured":"Bastuji-Garin\u00a0S, Fouchard\u00a0N, Bertocchi\u00a0M, Roujeau\u00a0JC, Revuz\u00a0J, Wolkenstein\u00a0P (2000) SCORTEN: a\u00a0severity-of-illness score for toxic epidermal necrolysis. J\u00a0Invest Dermatol 115(2):149\u2013153","journal-title":"J Invest Dermatol"},{"issue":"1","key":"723_CR27","doi-asserted-by":"crossref","first-page":"5","DOI":"10.5070\/D397D8T291","volume":"8","author":"PD Ghislain","year":"2002","unstructured":"Ghislain\u00a0PD, Roujeau\u00a0JC (2002) Treatment of severe drug reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis and hypersensitivity syndrome. Dermatol Online\u00a0J 8(1):5","journal-title":"Dermatol Online J"},{"issue":"6","key":"723_CR28","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1001\/jamadermatol.2016.5668","volume":"153","author":"S Zimmermann","year":"2017","unstructured":"Zimmermann\u00a0S, Sekula\u00a0P, Venhoff\u00a0M, Motschall\u00a0E, Knaus\u00a0J, Schumacher\u00a0M et al (2017) Systemic Immunomodulating therapies for Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis. JAMA Dermatol 153(6):514\u2013522","journal-title":"JAMA Dermatol"},{"issue":"1","key":"723_CR29","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1001\/archderm.139.1.33","volume":"139","author":"N Bachot","year":"2003","unstructured":"Bachot\u00a0N, Revuz\u00a0J, Roujeau\u00a0JC (2003) Intravenous immunoglobulin treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis: a\u00a0prospective noncomparative study showing no benefit on mortality or progression. Arch Dermatol 139(1):33\u201336","journal-title":"Arch Dermatol"},{"issue":"5","key":"723_CR30","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1111\/j.1610-0387.2009.07289_supp.x","volume":"8","author":"I Hanken","year":"2010","unstructured":"Hanken\u00a0I, Schimmer\u00a0M, Sander\u00a0CA (2010) Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis. J\u00a0Dtsch Dermatol Ges 8(5):341\u2013346","journal-title":"J Dtsch Dermatol Ges"}],"container-title":["Medizinische Klinik - Intensivmedizin und Notfallmedizin"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00063-020-00723-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00063-020-00723-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00063-020-00723-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T04:21:04Z","timestamp":1696652464000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00063-020-00723-x"}},"subtitle":["Von der Gonorrh\u00f6 zum Angio\u00f6dem","From gonorrhea to angioedema"],"short-title":[],"issued":{"date-parts":[[2020,9,10]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["723"],"URL":"https:\/\/doi.org\/10.1007\/s00063-020-00723-x","relation":{},"ISSN":["2193-6218","2193-6226"],"issn-type":[{"value":"2193-6218","type":"print"},{"value":"2193-6226","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,10]]},"assertion":[{"value":"2 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"<b>D.\u00a0Neumayer<\/b>: A.\u00a0Finanzielle Interessen: Honorare: AbbVie, Celgene, Leo Pharma, Novartis, Janssen Cilag | Kostenerstattung f\u00fcr Reise\u2011, \u00dcbernachtungskosten und Teilnehmergeb\u00fchren: AbbVie, Celgene, Leo Pharma, Lilly, Novartis, Pfizer, Janssen Cilag, Almirall. \u2013 Berater: AbbVie, Leo Pharma, Novartis, Pfizer, Janssen Cilag. \u2013 B.\u00a0Nichtfinanzielle Interessen: angestellte Dermatologin, Funktionsober\u00e4rztin, Abteilung f\u00fcr Dermatologie und Venerologie, Universit\u00e4tsklinikum K\u00f6ln, Studien\u00e4rztin f\u00fcr Psoriasisstudien. <b>R.\u00a0Rongisch<\/b>: A.\u00a0Finanzielle Interessen: Forschungsstipendium der DFG, CCSP-Programm K\u00f6ln. \u2013 Referentenhonorar oder Kostenerstattung als passiver Teilnehmer: DDG-Kongresssponsoring der Firma Celgene 2019. \u2013 B.\u00a0Nichtfinanzielle Interessen: Assistenzarzt, Klinik f\u00fcr Dermatologie und Venerologie, Universit\u00e4tsklinikum K\u00f6ln. <b>J.\u00a0K\u00e4stle<\/b>: A.\u00a0Finanzielle Interessen: J.\u00a0K\u00e4stle gibt an, dass kein finanzieller Interessenkonflikt besteht. \u2013 B.\u00a0Nichtfinanzielle Interessen: angestellte wissenschaftliche Mitarbeiterin, Institut f\u00fcr Dermatologie und Venerologie, Universit\u00e4tsklinikum K\u00f6ln.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}