{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T09:20:06Z","timestamp":1769246406054,"version":"3.49.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Klin Intensivmed Notfmed"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s00063-020-00730-y","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T12:02:56Z","timestamp":1599134576000},"page":"539-544","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Labordiagnostik in der Intensivmedizin","Laboratory testing in intensive care medicine"],"prefix":"10.1007","volume":"115","author":[{"given":"S.","family":"Petros","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Weidhase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,9,3]]},"reference":[{"key":"730_CR1","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.amsu.2020.02.002","volume":"51","author":"BEL Vrijsen","year":"2020","unstructured":"Vrijsen\u00a0BEL, Naaktgeboren\u00a0CA, Vos\u00a0LM et\u00a0al (2020) Inappropriate laboratory testing in internal medicine inpatients: prevalence, causes and interventions. Ann Med Surg 51:48\u201353","journal-title":"Ann Med Surg"},{"key":"730_CR2","doi-asserted-by":"publisher","first-page":"e184521","DOI":"10.1001\/jamanetworkopen.2018.4521","volume":"1","author":"PD Tyler","year":"2018","unstructured":"Tyler\u00a0PD, Du\u00a0H, Feng\u00a0M et\u00a0al (2018) Assessment of intensive care unit laboratory values that differ from reference ranges and association with patient mortality and length of stay. JAMA Netw Open 1:e184521","journal-title":"JAMA Netw Open"},{"key":"730_CR3","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1513\/AnnalsATS.201407-325OC","volume":"12","author":"WG Anderson","year":"2015","unstructured":"Anderson\u00a0WG, Cimino\u00a0JW, Ernecoff\u00a0NC et\u00a0al (2015) A multicenter study of key stakeholders\u2019 perspectives on communicating with surrogates about prognosis in intensive care units. Ann Am Thorac Soc 12:142\u2013152","journal-title":"Ann Am Thorac Soc"},{"key":"730_CR4","doi-asserted-by":"publisher","first-page":"e78962","DOI":"10.1371\/journal.pone.0078962","volume":"8","author":"M Zhi","year":"2013","unstructured":"Zhi\u00a0M, Ding\u00a0EL, Theisen-Toupal\u00a0J et al (2013) The landscape of inappropriate laboratory testing: a\u00a015-year meta-analysis. Plos One 8:e78962","journal-title":"Plos One"},{"key":"730_CR5","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1007\/s12630-016-0793-9","volume":"64","author":"M Mikhaeil","year":"2017","unstructured":"Mikhaeil\u00a0M, Day\u00a0AG, Ilan\u00a0R (2017) Non-essential blood tests in the intensive care unit: a\u00a0prospective observational study. Can J Anaesth 64:290\u2013295","journal-title":"Can J Anaesth"},{"issue":"Suppl 2","key":"730_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/cc2832","volume":"8","author":"LM Napolitano","year":"2004","unstructured":"Napolitano\u00a0LM (2004) Scope of the problem: epidemiology of anemia and use of blood transfusions in critical care. Crit Care 8(Suppl 2):1\u20138","journal-title":"Crit Care"},{"key":"730_CR7","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.aucc.2015.06.002","volume":"29","author":"AJ Ullman","year":"2016","unstructured":"Ullman\u00a0AJ, Keogh\u00a0S, Coyer\u00a0F et\u00a0al (2016) \u2018True blood\u2019 the critical care story: an audit of blood sampling practice across three adult, paediatric and neonatal intensive care settings. Aust Crit Care 29:90\u201395","journal-title":"Aust Crit Care"},{"key":"730_CR8","doi-asserted-by":"publisher","first-page":"191","DOI":"10.17219\/acem\/32065","volume":"25","author":"N Jakacka","year":"2016","unstructured":"Jakacka\u00a0N, Snarski\u00a0E, Mekuria\u00a0S (2016) Prevention of iatrogenic anemia in critical and neonatal care. Adv Clin Exp Med 25:191\u2013197","journal-title":"Adv Clin Exp Med"},{"key":"730_CR9","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1186\/s13054-019-2511-9","volume":"23","author":"NS Whitehead","year":"2019","unstructured":"Whitehead\u00a0NS, Williams\u00a0LO, Meleth\u00a0S et\u00a0al (2019) Interventions to prevent iatrogenic anemia: a\u00a0laboratory medicine best practices systematic review. Crit Care 23:278","journal-title":"Crit Care"},{"key":"730_CR10","doi-asserted-by":"publisher","first-page":"402","DOI":"10.3343\/alm.2018.38.5.402","volume":"38","author":"RS Bindraban","year":"2018","unstructured":"Bindraban\u00a0RS, Ten Berg\u00a0MJ, Naaktgeboren\u00a0CA et\u00a0al (2018) Reducing test utilization in hospital settings: a narrative review. Ann Lab Med 38:402\u2013412","journal-title":"Ann Lab Med"},{"key":"730_CR11","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.cmet.2018.03.008","volume":"27","author":"GA Brooks","year":"2018","unstructured":"Brooks\u00a0GA (2018) The science and translation of lactate shuttle theory. Cell Metab 27:757\u2013785","journal-title":"Cell Metab"},{"key":"730_CR12","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s12871-018-0515-7","volume":"18","author":"A Alatassi","year":"2018","unstructured":"Alatassi\u00a0A, Habbal\u00a0M, Tamim\u00a0H et al (2018) Association between troponin\u2011I levels and outcome in critically ill patients admitted to non-cardiac intensive care unit with high prevalence of cardiovascular risk factors. BMC Anesthesiol 18:54","journal-title":"BMC Anesthesiol"},{"key":"730_CR13","doi-asserted-by":"publisher","first-page":"2446","DOI":"10.1001\/archinte.166.22.2446","volume":"166","author":"W Lim","year":"2006","unstructured":"Lim\u00a0W, Qushmaq\u00a0I, Devereaux\u00a0PJ et\u00a0al (2006) Elevated cardiac troponin measurements in critically ill patients. Arch Intern Med 166:2446\u20132454","journal-title":"Arch Intern Med"},{"key":"730_CR14","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1007\/BF01709751","volume":"22","author":"JL Vincent","year":"1996","unstructured":"Vincent\u00a0JL, Moreno\u00a0R, Takala\u00a0J et al (1996) The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 22:707\u2013710","journal-title":"Intensive Care Med"},{"key":"730_CR15","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","volume":"315","author":"M Singer","year":"2016","unstructured":"Singer\u00a0M, Deutschman\u00a0CS, Seymour\u00a0CW et al (2016) The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 315:801\u2013810","journal-title":"JAMA"},{"key":"730_CR16","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s11739-009-0277-9","volume":"4","author":"C Picariello","year":"2009","unstructured":"Picariello\u00a0C, Lazzeri\u00a0C, Chiostri\u00a0M et\u00a0al (2009) Procalcitonin in patients with acute coronary syndromes and cardiogenic shock submitted to percutaneous coronary intervention. Intern Emerg Med 4:403\u2013408","journal-title":"Intern Emerg Med"},{"key":"730_CR17","doi-asserted-by":"publisher","first-page":"e0138566","DOI":"10.1371\/journal.pone.0138566","volume":"10","author":"JA Rule","year":"2015","unstructured":"Rule\u00a0JA, Hynan\u00a0LS, Attar\u00a0N et\u00a0al (2015) Procalcitonin identifies cell injury, not bacterial infection, in acute liver failure. PLoS ONE 10:e138566","journal-title":"PLoS ONE"},{"key":"730_CR18","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1007\/s00134-017-4683-6","volume":"43","author":"A Rhodes","year":"2017","unstructured":"Rhodes\u00a0A, Evans\u00a0LE, Alhazzani\u00a0W et\u00a0al (2017) Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med 43:304\u2013377","journal-title":"Intensive Care Med"},{"key":"730_CR19","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1007\/s00063-020-00671-6","volume":"115","author":"FM Brunkhorst","year":"2020","unstructured":"Brunkhorst\u00a0FM, Weigand\u00a0MA, Pletz\u00a0M et al (2020) S3 guideline sepsis-prevention, diagnosis, treatment, and aftercare: summary of the strong recommendations. Med Klin Intensivmed Notfmed 115:178\u2013188","journal-title":"Med Klin Intensivmed Notfmed"},{"key":"730_CR20","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1097\/01.CCM.0000168253.91200.83","volume":"33","author":"T Calandra","year":"2005","unstructured":"Calandra\u00a0T, Cohen\u00a0J (2005) The international sepsis forum consensus conference on definitions of infection in the intensive care unit. Crit Care Med 33:1538\u20131548","journal-title":"Crit Care Med"},{"key":"730_CR21","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1097\/CCM.0000000000003557","volume":"47","author":"KA Artis","year":"2019","unstructured":"Artis\u00a0KA, Bordley\u00a0J, Mohan\u00a0V et\u00a0al (2019) Data omission by physician trainees on ICU rounds. Crit Care Med 47:403\u2013409","journal-title":"Crit Care Med"},{"key":"730_CR22","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1007\/s00134-009-1438-z","volume":"35","author":"G Prat","year":"2009","unstructured":"Prat\u00a0G, Lef\u00e8vre\u00a0M, Nowak\u00a0E et\u00a0al (2009) Impact of clinical guidelines to improve appropriateness of laboratory tests and chest radiographs. Intensive Care Med 35:1047\u20131053","journal-title":"Intensive Care Med"},{"key":"730_CR23","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s13012-020-00981-5","volume":"15","author":"M Foster","year":"2020","unstructured":"Foster\u00a0M, Presseau\u00a0J, Mccleary\u00a0N et\u00a0al (2020) Audit and feedback to improve laboratory test and transfusion ordering in critical care: a\u00a0systematic review. Implement Sci 15:46","journal-title":"Implement Sci"},{"key":"730_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4266\/acc.2018.00052","volume":"33","author":"RM Kleinpell","year":"2018","unstructured":"Kleinpell\u00a0RM, Farmer\u00a0JC, Pastores\u00a0SM (2018) Reducing unnecessary testing in the intensive care unit by choosing wisely. Acute Crit Care 33:1\u20136","journal-title":"Acute Crit Care"},{"key":"730_CR25","first-page":"763","volume":"21","author":"C Minerowicz","year":"2015","unstructured":"Minerowicz\u00a0C, Abel\u00a0N, Hunter\u00a0K et\u00a0al (2015) Impact of weekly feedback on test ordering patterns. Am J Manag Care 21:763\u2013768","journal-title":"Am J Manag Care"},{"key":"730_CR26","doi-asserted-by":"publisher","first-page":"e000689","DOI":"10.1136\/bmjoq-2019-000689","volume":"8","author":"R Harb","year":"2019","unstructured":"Harb\u00a0R, Hajdasz\u00a0D, Landry\u00a0ML et\u00a0al (2019) Improving laboratory test utilisation at the multihospital Yale New Haven Health System. BMJ Open Qual 8:e689","journal-title":"BMJ Open Qual"},{"key":"730_CR27","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.ijmedinf.2012.11.017","volume":"82","author":"F Cismondi","year":"2013","unstructured":"Cismondi\u00a0F, Celi\u00a0LA, Fialho\u00a0AS et\u00a0al (2013) Reducing unnecessary lab testing in the ICU with artificial intelligence. Int J Med Inform 82:345\u2013358","journal-title":"Int J Med Inform"}],"container-title":["Medizinische Klinik - Intensivmedizin und Notfallmedizin"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00063-020-00730-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00063-020-00730-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00063-020-00730-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T22:01:59Z","timestamp":1630706519000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00063-020-00730-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,3]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["730"],"URL":"https:\/\/doi.org\/10.1007\/s00063-020-00730-y","relation":{},"ISSN":["2193-6218","2193-6226"],"issn-type":[{"value":"2193-6218","type":"print"},{"value":"2193-6226","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,3]]},"assertion":[{"value":"19 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"S.\u00a0Petros und L.\u00a0Weidhase geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}