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Die eCPR wird im therapierefrakt\u00e4ren Kreislaufstillstand etabliert, um Diagnostik und Therapie reversibler Ursachen, wie Herzinfarkt, Lungenembolie, akzidentielle Hypothermie, Intoxikationen mit herzwirksamen Substanzen und akute Hypoxie, zu erm\u00f6glichen. Selektionskriterien f\u00fcr eCPR umfassen prognostische Reanimationsfaktoren, wie beobachteter Kreislaufstillstand, Start von Reanimationsma\u00dfnahmen in &lt;\u202f5\u202fmin, schockbarer Erstrhythmus, Zeichen effektiver cCPR wie Lebenszeichen w\u00e4hrend der Reanimation, anhaltendes Kammerflimmern, intermittierende Phasen von Spontankreislauf oder anhaltendes endtidales CO<jats:sub>2<\/jats:sub> &gt;\u202f10\u202fmm\u202fHg, Patientenalter und Gesundheitszustand. Die Zeitspanne vom Kreislaufstillstand bis zur eCPR ist eine der wichtigsten Determinanten f\u00fcr neurologisch gutes \u00dcberleben und sollte &lt;\u202f60\u202fmin liegen. F\u00fcr die Einhaltung dieser Zielvorgabe muss eine entschlossene \u201eLoad-and-Go\u201c-Strategie mit fr\u00fchzeitiger Patientenselektion und raschem Transport unter mechanischer cCPR in ein eCPR-Zentrum verfolgt werden, oder es wird versucht, die eCPR pr\u00e4klinisch zum Einsatz zu bringen. Zwei randomisierte kontrollierte eCPR-Studien demonstrierten \u00dcberlebensraten von 43\u202f% bzw. 31,5\u202f% bei Patienten mit anhaltendem Kammerflimmern bzw. kardialem Kreislaufstillstand. Ob diese Ergebnisse au\u00dferhalb einzelner hochspezialisierter Zentren anwendbar sind, ist wie die Frage nach der besten pr\u00e4klinischen und innerklinischen Strategie Gegenstand zuk\u00fcnftiger Studien.<\/jats:p>","DOI":"10.1007\/s00063-022-00913-9","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T10:07:08Z","timestamp":1649671628000},"page":"325-332","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Extrakorporale Reanimation \u2013 Kriterien, Bedingungen, Outcome","Extracorporeal resuscitation\u2014criteria, prerequisites, outcome"],"prefix":"10.1007","volume":"117","author":[{"given":"Ingrid","family":"Magnet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Poppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"key":"913_CR1","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.resuscitation.2021.02.010","volume":"161","author":"J Soar","year":"2021","unstructured":"Soar\u00a0J, B\u00f6ttiger\u00a0BW, Carli\u00a0P et\u00a0al (2021) European resuscitation council guidelines 2021: adult advanced life support. 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