{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:38:47Z","timestamp":1740166727600,"version":"3.37.3"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Private Universit\u00e4t Witten\/Herdecke gGmbH"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Klin Intensivmed Notfmed"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund und Ziel der Arbeit<\/jats:title>\n                <jats:p>Die pulmonale Manifestation von COVID-19 wird anhand standardisierter CT-morphologischer Kriterien beschrieben. In dieser Studie untersuchten wir m\u00f6gliche Assoziationen zwischen dem CT-morphologischen Infiltratmuster bei COVID-19-Pneumonie und typischen Komorbidit\u00e4ten sowie dem klinischen Verlauf.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methoden<\/jats:title>\n                <jats:p>Wir analysierten klinische Daten und pulmonale Bildgebung von 61\u00a0Patienten mit positivem PCR-Test. Die pulmonalen Ver\u00e4nderungen wurden kategorisiert und auf Zusammenh\u00e4nge mit vorbestehenden Komorbidit\u00e4ten und dem klinischen Verlauf \u00fcberpr\u00fcft.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Im Vergleich zu Patienten mit untypischen Infiltratmustern (2\/19, 10,5\u202f%) wurden 25\u00a0Patienten mit typischen Infiltratmustern (25\/42, 59,5\u202f%) signifikant h\u00e4ufiger intensivmedizinisch behandelt (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001). Au\u00dferdem erhielten Patienten mit typischen Infiltratmustern im Vergleich zu Patienten mit untypischen Infiltratmustern h\u00e4ufiger eine nichtinvasive Beatmung (12\/42, 28,6\u202f%, <jats:italic>p<\/jats:italic>\u202f=\u2009,040) und High-flow-Therapie (8\/42, 19\u202f%, <jats:italic>p<\/jats:italic>\u202f=\u20090,041). Die Mortalit\u00e4t war ebenfalls h\u00f6her bei Patienten mit typischen Infiltratmustern, wobei 15 Patienten (15\/42, 35,7\u202f%) im Verlauf verstarben verglichen mit nur einem Patienten mit untypischem Infiltratmuster (1\/19, 10,5\u202f%, <jats:italic>p<\/jats:italic>\u202f=\u20090,012). Es konnte kein signifikanter Zusammenhang zwischen spezifischen Komorbidit\u00e4ten und dem resultierenden Infiltratmuster nachgewiesen werden.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Diskussion<\/jats:title>\n                <jats:p>Patienten mit einem typischen COVID-19-Infiltratmuster werden h\u00e4ufiger intensivmedizinisch behandelt und weisen eine h\u00f6here Mortalit\u00e4t auf. Weitere Analysen mit gr\u00f6\u00dferen Patientenkollektiven sind notwendig, um spezifische Risikofaktoren f\u00fcr eine typische COVID-19-Pneumonie zu identifizieren.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00063-023-01062-3","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T13:02:36Z","timestamp":1695646956000},"page":"384-390","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Korrelation zwischen Komorbidit\u00e4ten und Ver\u00e4nderungen des Lungenparenchyms im CT des Thorax bei Patienten mit COVID-19-Pneumonie","Correlation between comorbidities and thoracic CT manifestations of COVID-19 pneumonia"],"prefix":"10.1007","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7519-424X","authenticated-orcid":false,"given":"Nima","family":"Nadem Boueini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Haage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine","family":"Abanador-Kamper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Kamper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,25]]},"reference":[{"key":"1062_CR1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/RTI.0000000000000524","volume":"35","author":"S Simpson","year":"2020","unstructured":"Simpson\u00a0S, Kay\u00a0FU, Abbara\u00a0S et al (2020) Radiological society of North America expert consensus statement on reporting chest CT findings related to COVID-19. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}