{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T19:55:48Z","timestamp":1773604548826,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2011,1,24]],"date-time":"2011-01-24T00:00:00Z","timestamp":1295827200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1007\/s00066-010-2155-9","type":"journal-article","created":{"date-parts":[[2011,2,18]],"date-time":"2011-02-18T17:19:42Z","timestamp":1298049582000},"page":"114-119","source":"Crossref","is-referenced-by-count":38,"title":["Impact of Radiotherapy on Pain Relief and Recalcification in Plasma Cell Neoplasms","Wirkung der Strahlentherapie auf Schmerzlinderung und Rekalzifizierung beim Multiplen Myelom und Plasmozytom: Langzeit-Erfahrung"],"prefix":"10.1007","volume":"187","author":[{"given":"Mario","family":"Balducci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Chiesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Manfrida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Za","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Frascino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berardino","family":"De Bari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Hohaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Cellini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Mantini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Roberto","family":"D\u2019Agostino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Antonietta","family":"Gambacorta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonello","family":"Leone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Valentini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerio","family":"De Stefano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,1,24]]},"reference":[{"key":"2155_CR1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0167-8140(91)90144-6","volume":"20","author":"Adamietz","year":"1991","unstructured":"Adamietz IA, Schober C, Schulte RW, et al. Palliative radiotherapy in plasma cell myeloma. Radiother Oncol 1991;20:111\u20136","journal-title":"Radiother Oncol"},{"key":"2155_CR2","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1200\/JCO.2002.06.037","volume":"20","author":"Berenson","year":"2002","unstructured":"Berenson JR , Hillner BE, Kyle RA, et al. American Society of Clinical Oncol-ogy Bisphosphonates Expert Panel American Society of Clinical Oncology Clinical Practice Guidelines: The Role of Bisphosphonates in Multiple My-eloma. J Clin Oncol 2002;20:3719\u201336","journal-title":"J Clin Oncol"},{"key":"2155_CR3","doi-asserted-by":"crossref","unstructured":"Bone Pain Trial Working Party. 8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a mul-tifraction schedule over 12 months of patient follow-up. Radiother Oncol 1999;52:111\u201321","DOI":"10.1016\/S0167-8140(99)00097-3"},{"key":"2155_CR4","unstructured":"Bruno B, Boccadoro M, Palombo A, et al. Mieloma multiplo e neoplasie plas-macellulari. In: Bonadonna G (ed) Medicina Oncologica, 7th edn. Milano, Masson, 2003:1441\u20138"},{"key":"2155_CR5","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1200\/JCO.1987.5.11.1811","volume":"5","author":"Chak","year":"1987","unstructured":"Chak LY, Cox RS, Bostwick DG, et al. Solitary plasmacytoma of bone: treat-ment, progression, and survival. J Clin Oncol 1987;5:1811\u20135","journal-title":"J Clin Oncol"},{"key":"2155_CR6","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1089\/jpm.2006.9.850","volume":"9","author":"Chow","year":"2006","unstructured":"Chow E, Doyle M, Li K, et al. Mild, moderate or severe pain categorized by patients with cancer with bone metastases. J of Pall Medicine 2006; 9:850\u20134","journal-title":"J of Pall Medicine"},{"key":"2155_CR7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.clon.2005.11.014","volume":"18","author":"Chow","year":"2006","unstructured":"Chow E, Hoskin PJ, Wu J, et al. A phase III International randomised trial comparing single with multiple fraction for Re-irradiation of Painful Bone Metastases: National Cancer Institute of Canada Clinical Trials Grops (NCIC CTG) SC 20. Clin Oncol 2006;18:125\u20138","journal-title":"Clin Oncol"},{"key":"2155_CR8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0167-8140(02)00170-6","volume":"64","author":"Chow","year":"2002","unstructured":"Chow E, Wu JS, Hoskin P, et al. International consensus on palliative radio-therapy endpoints for future clinical trials in bone metastases. Radiother Oncol 2002;64:275\u201380","journal-title":"Radiother Oncol"},{"key":"2155_CR9","first-page":"129","volume":"23","author":"Cleeland","year":"1994","unstructured":"Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inven-tory. Ann Acad Med Singapore 1994;23:129\u201338","journal-title":"Ann Acad Med Singapore"},{"key":"2155_CR10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1053\/ctrv.2000.0210","volume":"27","author":"Coleman","year":"2001","unstructured":"Coleman RE. Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 2001;27:165\u201376","journal-title":"Cancer Treat Rev"},{"key":"2155_CR11","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","volume":"31","author":"Cox","year":"1995","unstructured":"Cox JD, Stetz J, Pajak TF et al. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 1995;31:1341\u20136","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2155_CR12","doi-asserted-by":"crossref","unstructured":"Criteria for the classification of monoclonal gammopathies multiple myeloma and related disorders: a report of the International Myeloma Working Group Br J Haematol 2003;121:749\u201357","DOI":"10.1046\/j.1365-2141.2003.04355.x"},{"key":"2155_CR13","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1365-2141.2008.07421.x","volume":"144","author":"Dores","year":"2008","unstructured":"Dores GM, Landgren O, McGlynn KA, et al. Plasmocytoma of bone, extramedullary plasmocytoma, and multile myeloma : incidence and survival in the United States, 1992\u20132004. Br J Haematol 2008;144:86\u201394","journal-title":"Br J Haematol"},{"key":"2155_CR14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0360-3016(89)90008-4","volume":"16","author":"Frassica","year":"1989","unstructured":"Frassica D, Frassica FJ, Schray MF, et al. Solitary plasmacytoma of bone: Mayo Clinic experience. Int J Radiat Oncol Biol Phys 1989;16:43\u20138","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2155_CR15","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s00066-010-2110-9","volume":"186","author":"Freundt","year":"2010","unstructured":"Freundt K, Meyners T, Bajrovic A, et al. Radiotherapy for oligometastatic disease in patients with spinal cord compression (MSCC) from relatively adioresistant tumors. Strahlenther Onkol 2010;186:218\u201323","journal-title":"Strahlenther Onkol"},{"key":"2155_CR16","unstructured":"Gertz MA, Chen MG (2007) Multiple myeloma and other plasma cell neo-plasms. In: Gunderson LL (ed) Clinical Radiation Oncology. 2nd edn, Phila-delphia: Churchill Levingstone Elsevier 2007:1753\u201372"},{"key":"2155_CR17","unstructured":"International Commission on Radiation Units and Measurements. ICRU Report 50. Prescribing, recording, and reporting photon beam therapy. Bethesda, MD: ICRU, 1993"},{"key":"2155_CR18","unstructured":"International Commission on Radiation Units and Measurements. ICRU Report 62. Prescribing, recording, and reporting photon beam therapy (Supplement to ICRU Report 50). Bethesda, MD: ICRU, 1999"},{"key":"2155_CR19","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/S0360-3016(02)04147-0","volume":"55","author":"Wu","year":"2003","unstructured":"Wu JS-Y, Wong R, Johnston M, Bezjak A, et al. Meta-analysis of dose-frac-tionation radiotherapy trials for the palliation of painful bone metastases. Int J Radiat Oncol Biol Phys 2003;55:594\u2013605","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2155_CR20","doi-asserted-by":"crossref","first-page":"457","DOI":"10.2307\/2281868","volume":"53","author":"Kaplan","year":"1958","unstructured":"Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J Am Stat Assoc 1958;53:457\u201381","journal-title":"J Am Stat Assoc"},{"key":"2155_CR21","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1007\/s000660050061","volume":"175","author":"Kowing","year":"1999","unstructured":"Kowing S, Budach V. Remineralization and pain relief in bone metastases after different radiotherapy fractions (10 times 3 Gy vs. 1 time 8 Gy). A prospective study. Strahlenther Onkol 1999;175:500\u20138","journal-title":"Strahlenther Onkol"},{"key":"2155_CR22","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0360-3016(93)90308-I","volume":"25","author":"Leigh","year":"1993","unstructured":"Leigh BR, Kurtts TA, Mack CF, et al. Radiation therapy for the palliation of multiple myeloma. Int J Radiat Oncol Biol Phys 1993;25:801\u20134","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2155_CR23","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/1097-0142(19800215)45:4<647::AID-CNCR2820450405>3.0.CO;2-E","volume":"45","author":"Mill","year":"1980","unstructured":"Mill WB, Griffith R. The role of radiation therapy in the management of plasma cell tumours. Cancer 1980;45:647\u2013652","journal-title":"Cancer"},{"key":"2155_CR24","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s00066-010-2111-8","volume":"186","author":"Momm","year":"2010","unstructured":"Momm F, Lingg S, Xander C, et al. The situation of radiation oncology pa-tients\u2019 relatives. A stocktaking. Strahlenther Onkol 2010;186(6):344\u201350","journal-title":"Strahlenther Onkol"},{"key":"2155_CR25","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/PL00002317","volume":"176","author":"Mose","year":"2000","unstructured":"Mose S, Pfitzener D, Rahn A, et al. Role of radiotherapy in the treatment of multiple myeloma. Strahlenther Onkol 2000;176:506\u201312","journal-title":"Strahlenther Onkol"},{"key":"2155_CR26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00066-009-1995-7","volume":"186","author":"M\u00fccke","year":"2010","unstructured":"M\u00fccke R, Seegenschmiedt MH, Heyd R, et al. Radiotherapy in painful gon-arthrosis. Results of a national patterns-of-care study. Strahlenther Onkol 2010;186:7\u201317","journal-title":"Strahlenther Onkol"},{"key":"2155_CR27","unstructured":"Munshi NC, Tricot G, Barlogie B. Plasma cell neoplasm. In: De Vita VT (ed) Principles and Practice of Oncology, 6th edn, Lippincott Williams & Wilkins Publishers, 2001:1816\u201337"},{"key":"2155_CR28","unstructured":"Perez CA, Brady LW, Halperin EC, et al. Principles and Practice of Radia-tion Oncology, Fourth Edition. Philadelphia PA, Lippincott Williams and Wilkins, 2004"},{"key":"2155_CR29","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.radonc.2004.09.017","volume":"75","author":"Roos","year":"2005","unstructured":"Roos DE, Turner SL, O\u2019Brien PC, et al. TROG 96.05 Randomized trial of 8 Gy in 1 versus 20 Gy in 5 fractions of radiotherapy for neuropathic pain due to bone metastases (Trans-Tasman Radiation Oncology Group, TROG 96.05) Radiother Oncol 2005;75(1):54\u201363","journal-title":"Radiother Oncol"},{"key":"2155_CR30","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00066-008-1808-4","volume":"184","author":"Stolting","year":"2008","unstructured":"Stolting T, Knauerhase H, Klautke G, et al. Total and single doses influence the effectiveness of radiotherapy in palliative treatment of palsmocytoma. Strahlenther Onkol 2008;184:465\u201372","journal-title":"Strahlenther Onkol"},{"key":"2155_CR31","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00066-009-2044-2","volume":"185","author":"Souchon","year":"2009","unstructured":"Souchon R, Wenz F, Sedlmayer F, et al. DEGRO practice guidelines for palliative radiotherapy of metastatic breast cancer: bone metastases and metastatic spinal cord compression (MSCC). Strahlenther Onkol 2009;185(7):417\u201324","journal-title":"Strahlenther Onkol"},{"key":"2155_CR32","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1387\/ijdb.041817lv","volume":"48","author":"Vakaet","year":"2004","unstructured":"Vakaet LA, Boteberg T. Pain control by ionizing radiation of bone metasta-sis. Int J Dev Biol Phys 2004;48:599\u2013606","journal-title":"Int J Dev Biol Phys"},{"key":"2155_CR33","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.ijrobp.2003.10.006","volume":"59","author":"Van Der Linden","year":"2004","unstructured":"Van Der Linden YM, Lok JJ, Steenland E, et al. Single fraction radiother-apy is efficacious: a further analysis of the Dutch Bone Metastasis Study controlling for the influence of retreatment. Int J Radiat Oncol Biol Phys 2004;59:528\u201337","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2155_CR34","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00066-010-2066-9","volume":"186","author":"Vassiliou","year":"2010","unstructured":"Vassiliou V, Tselis N, Kardamakis D. Osteonecrosis of the jaws: clinicopatho-logic and radiologic characteristics, preventive and therapeutic strategies. Strahlenther Onkol 2010;186:367\u201373","journal-title":"Strahlenther Onkol"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-010-2155-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00066-010-2155-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-010-2155-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T17:05:46Z","timestamp":1560013546000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00066-010-2155-9"}},"subtitle":["Long-Term Experience"],"short-title":[],"issued":{"date-parts":[[2011,1,24]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["2155"],"URL":"https:\/\/doi.org\/10.1007\/s00066-010-2155-9","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,24]]}}}