{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T06:32:36Z","timestamp":1772001156387,"version":"3.50.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T00:00:00Z","timestamp":1390521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1007\/s00066-013-0519-7","type":"journal-article","created":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T09:19:10Z","timestamp":1390382350000},"page":"408-410","source":"Crossref","is-referenced-by-count":10,"title":["Temozolomide-induced liver damage","Temozolomid-induzierter Leberschaden"],"prefix":"10.1007","volume":"190","author":[{"given":"F.","family":"Becker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Schmidtner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Semrau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Fietkau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,24]]},"reference":[{"key":"519_CR1","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJMoa043330","volume":"352","author":"Stupp","year":"2005","unstructured":"Stupp R, Mason WP, Bent MJ van den et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987\u2013996","journal-title":"N Engl J Med"},{"key":"519_CR2","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1007\/s00066-011-2230-x","volume":"187","author":"Gerstein","year":"2011","unstructured":"Gerstein J, Franz K, Steinbach JP et al (2011) Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution. Strahlenther Onkol 187:722\u2013728","journal-title":"Strahlenther Onkol"},{"key":"519_CR3","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00066-005-1314-x","volume":"181","author":"Kocher","year":"2005","unstructured":"Kocher M, Kunze S, Eich HT et al (2005) Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma. Strahlenther Onkol 181:157\u2013163","journal-title":"Strahlenther Onkol"},{"key":"519_CR4","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s00066-011-2242-6","volume":"187","author":"Guckenberger","year":"2011","unstructured":"Guckenberger M, Mayer M, Buttmann M et al (2011) Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme. Strahlenther Onkol 187:548\u2013554","journal-title":"Strahlenther Onkol"},{"key":"519_CR5","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/s00066-010-2101-x","volume":"186","author":"Balducci","year":"2010","unstructured":"Balducci M, Apicella G, Manfrida S et al (2010) Single-arm phase II study of conformal radiation therapy and temozolomide plus fractionated stereotactic conformal boost in high-grade gliomas: final report. Strahlenther Onkol 186:558\u2013564","journal-title":"Strahlenther Onkol"},{"key":"519_CR6","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s00066-010-2132-3","volume":"186","author":"Kopecky","year":"2010","unstructured":"Kopecky J, Priester P, Slovacek L et al (2010) Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide. Strahlenther Onkol 186:452\u2013457","journal-title":"Strahlenther Onkol"},{"key":"519_CR7","doi-asserted-by":"crossref","unstructured":"Schwabe U, Paffrath D (2010) Arzneiverordnungs-Report 2010. Springer Medizin, Berlin","DOI":"10.1007\/978-3-642-13380-0"},{"key":"519_CR8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/1748-717X-6-141","volume":"6","author":"Niewald","year":"2011","unstructured":"Niewald M, Berdel C, Fleckenstein J et al (2011) Toxicity after radiochemotherapy for glioblastoma using temozolomide\u2014a retrospective evaluation. Radiat Oncol 6:141","journal-title":"Radiat Oncol"},{"key":"519_CR9","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1212\/01.wnl.0000259430.48835.b5","volume":"68","author":"Chheda","year":"2007","unstructured":"Chheda MG, Drappatz J, Greenberger NJ et al (2007) Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note. Neurology 68:955\u2013956","journal-title":"Neurology"},{"key":"519_CR10","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1056\/NEJMc063696","volume":"356","author":"Grewal","year":"2007","unstructured":"Grewal J, Dellinger CA, Yung WK (2007) Fatal reactivation of hepatitis B with temozolomide. N Engl J Med 356:1591\u20131592","journal-title":"N Engl J Med"},{"key":"519_CR11","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11060-010-0354-y","volume":"103","author":"Goldbecker","year":"2011","unstructured":"Goldbecker A, Tryc AB, Raab P et al (2011) Hepatic encephalopathy after treatment with temozolomide. J Neurooncol 103:163\u2013166","journal-title":"J Neurooncol"},{"key":"519_CR12","first-page":"249","volume":"111","author":"Dixit","year":"2011","unstructured":"Dixit S, Hingorani M, Afzal P, Campbell AP (2011) Temozolomide induced liver injury. Acta Neurol Belg 111:249\u2013251","journal-title":"Acta Neurol Belg"},{"key":"519_CR13","unstructured":"o A (2011) Arzneimittelkommission der deutschen \u00c4rzteschaft. Dtsch \u00c4rztebl"},{"key":"519_CR14","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1007\/s00066-011-0026-7","volume":"188","author":"Niyazi","year":"2012","unstructured":"Niyazi M, Schwarz SB, Suchorska B, Belka C (2012) Radiotherapy with and without temozolomide in elderly patients with glioblastoma. Strahlenther Onkol 188:154\u2013159","journal-title":"Strahlenther Onkol"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-013-0519-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00066-013-0519-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-013-0519-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T02:31:15Z","timestamp":1558578675000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00066-013-0519-7"}},"subtitle":["A case report","Ein Fallbericht"],"short-title":[],"issued":{"date-parts":[[2014,1,24]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["519"],"URL":"https:\/\/doi.org\/10.1007\/s00066-013-0519-7","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,24]]}}}