{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T05:17:58Z","timestamp":1782451078645,"version":"3.54.5"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Medical University of Bialystok"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1007\/s00066-019-01480-3","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T12:03:01Z","timestamp":1560859381000},"page":"780-791","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["PET\/MRI-guided GTV delineation during radiotherapy planning in patients with squamous cell carcinoma of the tongue","PET\/MRT-gesteuerte GTV-Abgrenzung w\u00e4hrend der Bestrahlungsplanung bei Patienten mit Plattenepithelkarzinom der Zunge"],"prefix":"10.1007","volume":"195","author":[{"given":"Natalia","family":"Samo\u0142yk-Kogaczewska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6661-3182","authenticated-orcid":false,"given":"Ewa","family":"Sierko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Zuzda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patryk","family":"Gugnacki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Szumowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"Mojsak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Burzy\u0144ska-\u015aliwowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek Z.","family":"Wojtukiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Szczecina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota H.","family":"Jurgilewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"key":"1480_CR1","first-page":"6523","volume":"37","author":"E Farina","year":"2017","unstructured":"Farina E, Ferioli M, Morganti A et al (2017) 18F-Fdg-PET-guided planning and re-planning (adaptive) radiotherapy in head and neck cancer: current state of art. Anticancer Res 37:6523\u20136532","journal-title":"Anticancer Res"},{"key":"1480_CR2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.18282\/amor.v3.i3.200","volume":"3","author":"N Burela","year":"2017","unstructured":"Burela N, Soni T, Patni N et al (2017) A quantitative comparison of gross tumor volumes delineated on [18F]-FDG-PET\/CT scan and contrast-enhanced computed tomography scan in locally advanced head and neck carcinoma treated with intensity modulated radiotherapy. Adv Mod Oncol Res 3:143\u2013151","journal-title":"Adv Mod Oncol Res"},{"key":"1480_CR3","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.radonc.2017.02.005","volume":"123","author":"H Ligtenberg","year":"2017","unstructured":"Ligtenberg H, Jager E, Caldas-Magalhaes J et al (2017) Modality-specific target definition for laryngeal and hypopharyngeal cancer on FDG-PET, CT and MRI. Radiother Oncol 123:63\u201370","journal-title":"Radiother Oncol"},{"key":"1480_CR4","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1007\/s00066-010-2150-1","volume":"186","author":"G Lammering","year":"2010","unstructured":"Lammering G, De Ruysscher D, Lambin P et al (2010) The use of FDG-PET to target tumors by radiotherapy. Strahlenther Onkol 186:471\u2013481","journal-title":"Strahlenther Onkol"},{"key":"1480_CR5","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.semradonc.2017.08.003","volume":"28","author":"V Gr\u00e9goire","year":"2018","unstructured":"Gr\u00e9goire V, Thorwarth D, Lee J (2018) Molecular imaging-guided radiotherapy for the treatment of head-and-neck squamous cell carcinoma: does it fulfill the promises? Semin Radiat Oncol 28:35\u201345","journal-title":"Semin Radiat Oncol"},{"key":"1480_CR6","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1007\/s00066-005-1422-7","volume":"181","author":"AL Grosu","year":"2005","unstructured":"Grosu AL, Piert M, Molls M et\u00a0al (2005) Positron emission tomography for radiation treatment planning. Strahlenther Onkol 181:483\u2013499","journal-title":"Strahlenther Onkol"},{"key":"1480_CR7","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2017.00008","author":"K Wang","year":"2017","unstructured":"Wang K, Mullins B, Huang B (2017) Evaluation of PET\/MRI for tumor volume delineation for head and neck cancer. Front Oncol 8. \n                    https:\/\/doi.org\/10.3389\/fonc.2017.00008","journal-title":"Front Oncol"},{"key":"1480_CR8","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1200\/JCO.2009.24.6298","volume":"28","author":"M Lonneux","year":"2010","unstructured":"Lonneux M, Hamoir M, Gr\u00e9goire V (2010) Positron emission tomography with [18F] fluorodeoxyglucose improves staging and patient management in patients with head and neck squamous cell carcinoma: a\u00a0multicenter prospective study. J\u00a0Clin Oncol 28:1190\u20131195","journal-title":"J Clin Oncol"},{"key":"1480_CR9","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1097\/MNM.0000000000000687","volume":"38","author":"J Ma","year":"2017","unstructured":"Ma J, Han C, Guo Q (2017) Hybrid PET\/MRI-based delineation of gross tumor volume in head and neck cancer and tumor parameter analysis. Nucl Med Commun 38:642\u2013649","journal-title":"Nucl Med Commun"},{"key":"1480_CR10","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/S0360-3016(03)00346-8","volume":"57","author":"I Ciernik","year":"2003","unstructured":"Ciernik I, Dizendorf E, Von Schulthess G et\u00a0al (2003) Radiation treatment planning with an integrated positron emission and computed tomography (PET\/CT): a\u00a0feasibility study. Int J Radiat Oncol Biol Phys 57:853\u2013863","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1480_CR11","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.ijrobp.2006.12.029","volume":"68","author":"H Ashamalla","year":"2007","unstructured":"Ashamalla H, Guirgius A, Parikh K et\u00a0al (2007) The impact of positron emission tomography\/computed tomography in edge delineation of gross tumor volume for head and neck cancers. Int J Radiat Oncol Biol Phys 68:388\u2013395","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1480_CR12","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.radonc.2017.10.016","volume":"126","author":"V Gr\u00e9goire","year":"2018","unstructured":"Gr\u00e9goire V, Evans M, Le Q, Bourhis J, Budach V, Hamoir M et al (2018) Delineation of the primary tumour clinical target volumes (ctv-p) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: Airo, caca, dahanca, eortc, georcc, gortec, hknpcsg, hncig, iag-kht, lprhht, ncic ctg, ncri, nrg oncology, phns, sbrt, somera, sro, sshno, trog consensus guidelines. Radiother Oncol 126:3\u201324","journal-title":"Radiother Oncol"},{"key":"1480_CR13","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.radonc.2013.10.010","volume":"110","author":"V Gr\u00e9goire","year":"2014","unstructured":"Gr\u00e9goire V, Ang K, Budach W, Grau C, Hamoir M, O\u2019Sullivan B et\u00a0al (2014) Delineation of the neck node levels for head and neck tumors: a\u00a02013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines. Radiother Oncol 110:172\u2013181","journal-title":"Radiother Oncol"},{"key":"1480_CR14","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1109\/ICPR.1994.576361","volume-title":"Proceedings of the international conference on pattern recognition","author":"M Dubuisson","year":"1994","unstructured":"Dubuisson M, Jain A (1994) A modified Hausdorff distance for object matching. In: Proceedings of the international conference on pattern recognition Jerusalem, pp\u00a0566\u2013568"},{"key":"1480_CR15","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.radonc.2011.07.025","volume":"101","author":"G Delouya","year":"2011","unstructured":"Delouya G, Igidbashian L, Martel C et al (2011) 18F-FDG-PET imaging in radiotherapy tumor volume delineation in treatment of head and neck cancer. Radiother Oncol 101:362\u2013368","journal-title":"Radiother Oncol"},{"key":"1480_CR16","doi-asserted-by":"publisher","first-page":"14","DOI":"10.17229\/jdit.2018-0223-031","volume":"5","author":"O Ferrando","year":"2018","unstructured":"Ferrando O, Scolarob T, Foppiano F et al (2018) Target volume definition and dosimetric issues in radiotherapy treatment of head and neck disease with FDG-PET\/CT: A monocentric experience. J\u00a0Diagnostic Imaging Ther 5:14\u201319","journal-title":"J Diagnostic Imaging Ther"},{"key":"1480_CR17","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1186\/s13014-018-1091-1","volume":"13","author":"P Roberts","year":"2018","unstructured":"Roberts P, Ashesh B, Satyaseelan P et\u00a0al (2018) Upcoming imaging concepts and their impact on treatment planning and treatment response in radiation oncology. Radiat Oncol 13:146. \n                    https:\/\/doi.org\/10.1186\/s13014-018-1091-1","journal-title":"Radiat Oncol"},{"key":"1480_CR18","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1007\/s00066-014-0644-y","volume":"190","author":"C Doll","year":"2014","unstructured":"Doll C, Duncker-Rohr V, Weber W et al (2014) Influence of experience and qualification on PET-based target volume delineation. Strahlenther Onkol 190:555\u2013562","journal-title":"Strahlenther Onkol"},{"key":"1480_CR19","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1007\/s00066-006-1463-6","volume":"182","author":"W Jeanneret-Sozzi","year":"2006","unstructured":"Jeanneret-Sozzi W, Moeckli R, Mirimanoff RO et al (2006) The reasons for discrepancies in target volume delineation. Strahlenther Onkol 182:450\u2013457","journal-title":"Strahlenther Onkol"},{"key":"1480_CR20","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.radonc.2008.11.008","volume":"91","author":"M MacManus","year":"2009","unstructured":"MacManus M, Nestle U, Watanabe N et\u00a0al (2009) Use of PET and PET\/CT for radiation therapy planning: IAEA expert report 2006\u20132007. Radiother Oncol 91:85\u201394","journal-title":"Radiother Oncol"},{"key":"1480_CR21","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.ejmp.2018.05.013","volume":"49","author":"M Belli","year":"2018","unstructured":"Belli M, Mori M, Di Muzio N et al (2018) Quantifying the robustness of [18\u202fF] FDG-PET\/CT radiomic features with respect to tumor delineation in head and neck and pancreatic cancer patients. Phys Med 49:105\u2013111","journal-title":"Phys Med"},{"key":"1480_CR22","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.radonc.2009.12.021","volume":"94","author":"M Ahmed","year":"2010","unstructured":"Ahmed M, Schmidt M, Newbold K et\u00a0al (2010) The value of magnetic resonance imaging in target volume delineation of base of tongue tumours\u2014a\u00a0study using flexible surface coils. Radiother Oncol 94:161\u2013167","journal-title":"Radiother Oncol"},{"key":"1480_CR23","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.radonc.2015.06.007","volume":"116","author":"M Leclerc","year":"2015","unstructured":"Leclerc M, Lartigau E, Gr\u00e9goire V et al (2015) Primary tumor delineation based on 18FDG PET for locally advanced head and neck cancer treated by chemo-radiotherapy. Radiother Oncol 116:87\u201393","journal-title":"Radiother Oncol"},{"key":"1480_CR24","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.ijrobp.2008.04.059","volume":"73","author":"A Guido","year":"2009","unstructured":"Guido A, Fuccio L, Barbieri E et al (2009) Combined 18F-FDG-PET\/CT imaging in radiotherapy target delineation for head-and-neck cancer. Int J Radiat Oncol Biol Phys 73:759\u2013763","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1480_CR25","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1016\/j.ijrobp.2004.08.037","volume":"61","author":"A Paulino","year":"2005","unstructured":"Paulino A, Koshy M, Davis L et al (2005) Comparison of CT-and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys 61:1385\u20131392","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1480_CR26","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1186\/1748-717X-5-76","volume":"5","author":"C Kao","year":"2010","unstructured":"Kao C, Hsieh T, Chen S et al (2010) 18\u202fF-FDG PET\/CT-based gross tumor volume definition for radiotherapy in head and neck cancer: a\u00a0correlation study between suitable uptake value threshold and tumor parameters. Radiat Oncol 5:76. \n                    https:\/\/doi.org\/10.1186\/1748-717X-5-76","journal-title":"Radiat Oncol"},{"key":"1480_CR27","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.radonc.2012.11.008","volume":"106","author":"K Wang","year":"2013","unstructured":"Wang K, Heron D, Branstetter B et al (2013) Target delineation in stereotactic body radiation therapy for recurrent head and neck cancer: a\u00a0retrospective analysis of the impact of margins and automated PET-CT segmentation. Radiother Oncol 106:90\u201395","journal-title":"Radiother Oncol"},{"key":"1480_CR28","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.remn.2010.03.005","volume":"29","author":"M Guardia","year":"2010","unstructured":"Guardia M, Romasanta L, Castrej\u00f3n A et al (2010) Utility of PET-CT on radiotherapy planning of head and neck cancer. Our initial experience. Rev Esp Med Nucl 29:157\u2013164","journal-title":"Rev Esp Med Nucl"},{"key":"1480_CR29","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1097\/COC.0b013e318168ef82","volume":"31","author":"C Greco","year":"2008","unstructured":"Greco C, Nehmeh S, Lee N et al (2008) Evaluation of different methods of 18F-FDG-PET target volume delineation in the radiotherapy of head and neck cancer. Am J Clin Oncol 31:439\u2013445","journal-title":"Am J Clin Oncol"},{"key":"1480_CR30","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/s11864-017-0484-y","volume":"18","author":"S Huagn","year":"2017","unstructured":"Huagn S, O\u2019Sullivan B (2017) Overview of the 8th edition TNM classification for head and neck cancer. Curr Treat Options Oncol 18:40. \n                    https:\/\/doi.org\/10.1007\/s11864-017-0484-y","journal-title":"Curr Treat Options Oncol"},{"key":"1480_CR31","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1016\/j.clon.2012.04.002","volume":"24","author":"R Prestwich","year":"2012","unstructured":"Prestwich R, Sykes J, Scarsbrook A et al (2012) Improving target definition for head and neck radiotherapy: a\u00a0place for magnetic resonance imaging and 18-fluoride fluorodeoxyglucose positron emission tomography? Clin Oncol 24:577\u2013589","journal-title":"Clin Oncol"},{"key":"1480_CR32","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1016\/j.ijrobp.2007.07.2333","volume":"69","author":"D Schinagl","year":"2007","unstructured":"Schinagl D, Vogel W, Kaanders J et al (2007) Comparison of five segmentation tools for 18f-fluoro-deoxy-glucose\u2013positron emission tomography\u2013based target volume definition in head and neck cancer. Int J Radiat Oncol Biol Phys 69:1282\u20131289","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1480_CR33","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.radonc.2017.07.017","volume":"124","author":"A Mohamed","year":"2017","unstructured":"Mohamed A, Cardenas C, Rosenthal D et al (2017) Patterns-of-failure guided biological target volume definition for head and neck cancer patients: FDG-PET and dosimetric analysis of dose escalation candidate subregions. Radiother Oncol 124:248\u2013255","journal-title":"Radiother Oncol"},{"key":"1480_CR34","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/S1076-6332(03)00671-8","volume":"11","author":"KH Zou","year":"2004","unstructured":"Zou KH, Warfield SK, Bharatha A, Tempany CM, Kaus MR, Haker SJ et\u00a0al (2004) Statistical validation of image segmentation quality based on a\u00a0spatial overlap index. Acad Radiol 11:178\u2013189","journal-title":"Acad Radiol"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-019-01480-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00066-019-01480-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-019-01480-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T23:04:33Z","timestamp":1592348673000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00066-019-01480-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,18]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["1480"],"URL":"https:\/\/doi.org\/10.1007\/s00066-019-01480-3","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,18]]},"assertion":[{"value":"17 December 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical guidelines"}},{"value":"N.\u00a0Samo\u0142yk-Kogaczewska, E.\u00a0Sierko, K.\u00a0Zuzda, P.\u00a0Gugnacki, P.\u00a0Szumowski, M.\u00a0Mojsak, J.\u00a0Burzy\u0144ska-\u015aliwowska, M.Z.\u00a0Wojtukiewicz, K.\u00a0Szczecina and D.H.\u00a0Jurgilewicz declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants or on human tissue were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1975 Helsinki declaration and its later amendments or comparable ethical standards and was approved by the Bioethical Committee of the Medical University of Bia\u0142ystok, Poland. Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}