{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:22:37Z","timestamp":1778685757576,"version":"3.51.4"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T00:00:00Z","timestamp":1572480000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T00:00:00Z","timestamp":1572480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1007\/s00066-019-01530-w","type":"journal-article","created":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T16:05:18Z","timestamp":1572537918000},"page":"23-30","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Stereotactic body radiotherapy for ventricular tachycardia (cardiac radiosurgery)"],"prefix":"10.1007","volume":"196","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8811-5416","authenticated-orcid":false,"given":"David","family":"Krug","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Blanck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Demming","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Dottermusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karoline","family":"Koch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Hirt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Kotzott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Zaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Eidinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank-Andre","family":"Siebert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Dunst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Bonnemeier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,31]]},"reference":[{"key":"1530_CR1","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1056\/NEJMra1615244","volume":"380","author":"K Shivkumar","year":"2019","unstructured":"Shivkumar\u00a0K (2019) Catheter ablation of ventricular arrhythmias. N\u00a0Engl J Med 380:1555\u20131564","journal-title":"N Engl J Med"},{"issue":"10","key":"1530_CR2","doi-asserted-by":"publisher","first-page":"e190","DOI":"10.1016\/j.hrthm.2017.10.035","volume":"15","author":"SM Al-Khatib","year":"2018","unstructured":"Al-Khatib\u00a0SM, Stevenson\u00a0WG, Ackerman\u00a0MJ et al (2018) 2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: executive summary: a report of the American college of cardiology\/American heart association task force on clinical practice guidelines and the heart rhythm society. Heart Rhythm 15(10):e190\u2013e252","journal-title":"Heart Rhythm"},{"key":"1530_CR3","doi-asserted-by":"publisher","first-page":"2924","DOI":"10.1016\/j.jacc.2017.10.030","volume":"70(23","author":"SR Dukkipati","year":"2017","unstructured":"Dukkipati\u00a0SR, Koruth\u00a0JS, Choudry\u00a0S et al (2017) Catheter ablation of ventricular tachycardia in structural heart disease: indications, strategies, and outcomes-part II. J\u00a0Am Coll Cardiol 70(23:2924\u20132941","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"1530_CR4","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1056\/NEJMoa1513614","volume":"375","author":"JL Sapp","year":"2016","unstructured":"Sapp\u00a0JL, Wells\u00a0GA, Parkash\u00a0R et\u00a0al (2016) Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs. N\u00a0Engl J Med 375(2):111\u2013121","journal-title":"N Engl J Med"},{"issue":"3","key":"1530_CR5","doi-asserted-by":"publisher","first-page":"e000072","DOI":"10.1161\/JAHA.113.000072","volume":"2","author":"M Tokuda","year":"2013","unstructured":"Tokuda\u00a0M, Kojodjojo\u00a0P, Tung\u00a0S et\u00a0al (2013) Acute failure of catheter ablation for ventricular tachycardia due to structural heart disease: causes and significance. J\u00a0Am Heart Assoc 2(3):e72","journal-title":"J Am Heart Assoc"},{"issue":"17","key":"1530_CR6","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1016\/j.jacc.2017.02.044","volume":"69","author":"P Santangeli","year":"2017","unstructured":"Santangeli\u00a0P, Frankel\u00a0DS, Tung\u00a0R et\u00a0al (2017) Early mortality after catheter ablation of ventricular tachycardia in patients with structural heart disease. J\u00a0Am Coll Cardiol 69(17):2105\u20132115","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"1530_CR7","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.ccep.2016.10.006","volume":"9","author":"C Gianni","year":"2017","unstructured":"Gianni\u00a0C, Mohanty\u00a0S, Trivedi\u00a0C et\u00a0al (2017) Alternative approaches for ablation of resistant ventricular tachycardia. Card Electrophysiol Clin 9(1):93\u201398","journal-title":"Card Electrophysiol Clin"},{"key":"1530_CR8","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.hrthm.2010.02.010","volume":"7","author":"A Sharma","year":"2010","unstructured":"Sharma\u00a0A, Wong\u00a0D, Weidlich\u00a0G et\u00a0al (2010) Noninvasive stereotactic radiosurgery (CyberHeart) for creation of ablation lesions in the atrium. Heart Rhythm 7:802\u2013810","journal-title":"Heart Rhythm"},{"issue":"8","key":"1530_CR9","first-page":"e32","volume":"3","author":"PJ Maguire","year":"2011","unstructured":"Maguire\u00a0PJ, Gardner\u00a0E, Jack\u00a0AB et\u00a0al (2011) Cardiac Radiosurgery (CyberHeart) for treatment of arrhythmia: physiologic and histopathologic correlation in the porcine model. Cureus 3(8):e32","journal-title":"Cureus"},{"issue":"3","key":"1530_CR10","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1161\/CIRCEP.115.002765","volume":"8","author":"BW Loo Jr","year":"2015","unstructured":"Loo\u00a0BW Jr, Soltys\u00a0SG, Wang\u00a0L et\u00a0al (2015) Stereotactic ablative radiotherapy for the treatment of refractory cardiac ventricular arrhythmia. Circ Arrhythm Electrophysiol 8(3):748\u2013750","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"7","key":"1530_CR11","first-page":"e190","volume":"6","author":"J Cvek","year":"2014","unstructured":"Cvek\u00a0J, Neuwirth\u00a0R, Knybel\u00a0L et\u00a0al (2014) Cardiac radiosurgery for malignant ventricular tachycardia. Cureus 6(7):e190","journal-title":"Cureus"},{"issue":"24","key":"1530_CR12","doi-asserted-by":"publisher","first-page":"2325","DOI":"10.1056\/NEJMoa1613773","volume":"377","author":"PS Cuculich","year":"2017","unstructured":"Cuculich\u00a0PS, Schill\u00a0MR, Kashani\u00a0R et\u00a0al (2017) Noninvasive cardiac radiation for ablation of ventricular tachycardia. N\u00a0Engl J Med 377(24):2325\u20132336","journal-title":"N Engl J Med"},{"key":"1530_CR13","first-page":"00","volume":"138","author":"CG Robinson","year":"2018","unstructured":"Robinson\u00a0CG, Samson\u00a0PP, Moore\u00a0KMS et al (2018) Phase I\/II trial of electrophysiology-guided noninvasive cardiac radioablation for ventricular tachycardia. Circulation 138:0\u20130","journal-title":"Circulation"},{"issue":"19","key":"1530_CR14","first-page":"30623","volume":"3016","author":"NC Knutson","year":"2019","unstructured":"Knutson\u00a0NC, Samson\u00a0P, Hugo\u00a0G et\u00a0al (2019) Radiotherapy workflow and dosimetric analysis from a\u00a0phase I\/II trial of noninvasive cardiac radioablation for ventricular tachycardia. Int J Radiat Oncol Biol Phys 3016(19):30623\u201330626","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"1530_CR15","doi-asserted-by":"publisher","first-page":"3368","DOI":"10.1120\/jacmp.v12i2.3368","volume":"12","author":"J Grimm","year":"2011","unstructured":"Grimm\u00a0J, LaCouture\u00a0T, Croce\u00a0R et\u00a0al (2011) Dose tolerance limits and dose volume histogram evaluation for stereotactic body radiotherapy. J\u00a0Appl Clin Med Phys 12(2):3368","journal-title":"J Appl Clin Med Phys"},{"issue":"5","key":"1530_CR16","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s00066-015-0817-3","volume":"191","author":"B Gauter-Fleckenstein","year":"2015","unstructured":"Gauter-Fleckenstein\u00a0B, Israel\u00a0CW, Dorenkamp\u00a0M et al (2015) DEGRO\/DGK guideline for radiotherapy in patients with cardiac implantable electronic devices. Strahlenther Onkol 191(5):393\u2013404","journal-title":"Strahlenther Onkol"},{"issue":"2","key":"1530_CR17","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.radonc.2018.04.025","volume":"128","author":"R Jumeau","year":"2018","unstructured":"Jumeau\u00a0R, Ozsahin\u00a0M, Schwitter\u00a0J et al (2018) Rescue procedure for an electrical storm using robotic non-invasive cardiac radio-ablation. Radiother Oncol 128(2):189\u2013191","journal-title":"Radiother Oncol"},{"issue":"7","key":"1530_CR18","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1093\/europace\/euz133","volume":"21","author":"R Neuwirth","year":"2019","unstructured":"Neuwirth\u00a0R, Cvek\u00a0J, Knybel\u00a0L et\u00a0al (2019) Stereotactic radiosurgery for ablation of ventricular tachycardia. Europace.\u00a02019 Jul 1;21(7):1088\u20131095. \nhttps:\/\/doi.org\/10.1093\/europace\/euz133","journal-title":"Europace"},{"issue":"6","key":"1530_CR19","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.hrcr.2019.03.004","volume":"5","author":"EP Scholz","year":"2019","unstructured":"Scholz\u00a0EP, Seidensaal\u00a0K, Naumann\u00a0P et\u00a0al (2019) Risen from the dead: cardiac stereotactic ablative radiotherapy as last rescue in a\u00a0patient with refractory ventricular fibrillation storm. HeartRhythm Case Rep. 2019 Mar 21;5(6):329\u2013332. \nhttps:\/\/doi.org\/10.1016\/j.hrcr.2019.03.004","journal-title":"Risen"},{"key":"1530_CR20","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-019-01502-0","author":"F Stegner","year":"2019","unstructured":"Stegner\u00a0F, Hautmann\u00a0MG, Suess\u00a0C et\u00a0al (2019) Radiotherapy of patients with cardiac Implantable electronic device according to the DEGRO\/DGK guideline\u2014is the risk for errors overestimated? Strahlenther Onkol. \nhttps:\/\/doi.org\/10.1007\/s00066-019-01502-0","journal-title":"Strahlenther Onkol"},{"issue":"9","key":"1530_CR21","doi-asserted-by":"publisher","first-page":"1420","DOI":"10.1016\/j.hrthm.2018.04.015","volume":"15","author":"PC Zei","year":"2018","unstructured":"Zei\u00a0PC, Wong\u00a0D, Gardner\u00a0E et\u00a0al (2018) Safety and efficacy of stereotactic radioablation targeting pulmonary vein tissues in an experimental model. Heart Rhythm 15(9):1420\u20131427","journal-title":"Heart Rhythm"},{"issue":"3","key":"1530_CR22","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1016\/j.ijrobp.2014.02.036","volume":"89","author":"O Blanck","year":"2014","unstructured":"Blanck\u00a0O, Bode\u00a0F, Gebhard\u00a0M et\u00a0al (2014) Dose escalation study for cardiac radiosurgery in a\u00a0porcine model. Int J Radiat Oncol Biol Phys 89(3):590\u2013598","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"12","key":"1530_CR23","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.1093\/europace\/euu406","volume":"17","author":"F Bode","year":"2015","unstructured":"Bode\u00a0F, Blanck\u00a0O, Gebhard\u00a0M et al (2015) Pulmonary vein isolation by radiosurgery: implications for non-invasive treatment of atrial fibrillation. Europace 17(12):1868\u20131874","journal-title":"Europace"},{"issue":"7","key":"1530_CR24","first-page":"e705","volume":"8","author":"O Blanck","year":"2016","unstructured":"Blanck\u00a0O, Ipsen\u00a0S, Chan\u00a0MK et\u00a0al (2016) Treatment planning considerations for robotic guided cardiac radiosurgery for atrial fibrillation. Cureus 8(7):e705","journal-title":"Cureus"},{"issue":"8","key":"1530_CR25","first-page":"e738","volume":"8","author":"E Monroy","year":"2016","unstructured":"Monroy\u00a0E, Azpiri\u00a0J, De La Pena\u00a0C et al (2016) Late gadolinium enhancement cardiac magnetic resonance imaging post-robotic radiosurgical pulmonary vein isolation (RRPVI): first case in the world. Cureus 8(8):e738","journal-title":"Cureus"},{"issue":"25","key":"1530_CR26","doi-asserted-by":"publisher","first-page":"2872","DOI":"10.1016\/j.jacc.2015.10.026","volume":"66","author":"L Di Biase","year":"2015","unstructured":"Di Biase\u00a0L, Burkhardt\u00a0JD, Lakkireddy\u00a0D et\u00a0al (2015) Ablation of stable VTs versus substrate ablation in ischemic cardiomyopathy: the VISTA randomized multicenter trial. J\u00a0Am Coll Cardiol 66(25):2872\u20132882","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"1530_CR27","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1111\/jce.13843","volume":"30","author":"A Bhaskaran","year":"2019","unstructured":"Bhaskaran\u00a0A, Nayyar\u00a0S, Porta-S\u00e1nchez\u00a0A et al (2019) Exit sites on the epicardium rarely subtend critical diastolic path of ischemic VT on the endocardium: Implications for noninvasive ablation. J\u00a0Cardiovasc Electrophysiol 30(4):520\u2013527","journal-title":"J Cardiovasc Electrophysiol"},{"issue":"3","key":"1530_CR28","doi-asserted-by":"publisher","first-page":"118","DOI":"10.15420\/aer.2017.20.1","volume":"6","author":"AJ Graham","year":"2017","unstructured":"Graham\u00a0AJ, Orini\u00a0M, Lambiase\u00a0PD (2017) Limitations and challenges in mapping ventricular tachycardia: new technologies and future directions. Arrhythm Electrophysiol Rev 6(3):118\u2013124","journal-title":"Arrhythm Electrophysiol Rev"},{"key":"1530_CR29","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1007\/s00066-017-1151-8","volume":"193(10","author":"C Moustakis","year":"2017","unstructured":"Moustakis\u00a0C, Blanck\u00a0O, Ebrahimi\u00a0F et\u00a0al (2017) Planning benchmark study for SBRT of early stage NSCLC: results of the DEGRO working group stereotactic radiotherapy. Strahlenther Onkol 193(10:780\u2013790","journal-title":"Strahlenther Onkol"},{"key":"1530_CR30","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1007\/s00066-018-1314-2","volume":"194(9","author":"C Moustakis","year":"2018","unstructured":"Moustakis\u00a0C, Chan\u00a0MK, Kim\u00a0J et al (2018) Treatment planning for spinal radiosurgery: a competitive multi-platform bench mark challenge. Strahlenther Onkol 194(9:843\u2013854","journal-title":"Strahlenther Onkol"},{"key":"1530_CR31","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.radonc.2019.01.023","volume":"134","author":"J Boda-Heggemann","year":"2019","unstructured":"Boda-Heggemann\u00a0J, Jahnke\u00a0A, Chan\u00a0M et al (2019) In-vivo treatment accuracy analysis of active motion-compensated liver SBRT through registration of plan dose to post-therapeutic MRI-morphologic alterations. Radiother Oncol 134:158\u2013165","journal-title":"Radiother Oncol"},{"issue":"10","key":"1530_CR32","first-page":"e3445","volume":"10","author":"GA Weidlich","year":"2018","unstructured":"Weidlich\u00a0GA, Hacker\u00a0F, Bellezza\u00a0D et\u00a0al (2018) Ventricular tachycardia: a treatment comparison study of the CyberKnife with conventional linear accelerators. Cureus 10(10):e3445","journal-title":"Cureus"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-019-01530-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00066-019-01530-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-019-01530-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:05:01Z","timestamp":1604016301000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00066-019-01530-w"}},"subtitle":["First-in-patient treatment in Germany"],"short-title":[],"issued":{"date-parts":[[2019,10,31]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["1530"],"URL":"https:\/\/doi.org\/10.1007\/s00066-019-01530-w","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,31]]},"assertion":[{"value":"21 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 October 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical guidelines"}},{"value":"D.\u00a0Krug received honoraria from Merck Sharp & Dohme (MSD) outside of the submitted work. H.\u00a0Bonnemeier received honoraria from Boston Scientific (BSC) outside of the submitted work. O.\u00a0Blanck, T.\u00a0Demming, M.\u00a0Dottermusch, K.\u00a0Koch, M.\u00a0Hirt, L.\u00a0Kotzott, A.\u00a0Zaman, L.\u00a0Eidinger, F.-A.\u00a0Siebert, and J.\u00a0Dunst declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Before informing the patient about the possibility of CRS\/RA, the clinical ethics committee was consulted. During the discussion of CRS\/RA with the patient, a representative of the clinical ethics committee was present. The patient gave his written informed consent for collection and analysis of clinical data for this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}