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An RID predictive model was developed using dose to nine SWOARs and P\/A-VF data at 6\u00a0and 12\u202fmonths after treatment. A\u00a0total of 72\u00a0dosimetric features for each patient were extracted from DVH and analyzed with linear support vector machine classification (SVC), logistic regression classification (LRC), and random forest classification (RFC).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>38\u00a0patients were evaluable. The relevance of SWOARs DVH features emerged both at 6\u202fmonths (AUC 0.82 with SVC; 0.80 with LRC; and 0.83 with RFC) and at 12\u202fmonths (AUC 0.85 with SVC; 0.82 with LRC; and 0.94 with RFC). The SWOARs and the corresponding features with the highest relevance at 6\u202fmonths resulted as the base of tongue (V65 and D<jats:sub>mean<\/jats:sub>), the superior (D<jats:sub>mean<\/jats:sub>) and medium constrictor muscle (V45, V55; V65; D<jats:sub>mp<\/jats:sub>; D<jats:sub>mean<\/jats:sub>; D<jats:sub>max<\/jats:sub> and D<jats:sub>min<\/jats:sub>), and the parotid glands (D<jats:sub>mean<\/jats:sub> and D<jats:sub>mp<\/jats:sub>). On the contrary, the features with the highest relevance at 12\u202fmonths were the medium (V55; D<jats:sub>min<\/jats:sub> and D<jats:sub>mean<\/jats:sub>) and inferior constrictor muscles (V55, V65 D<jats:sub>min<\/jats:sub> and D<jats:sub>max<\/jats:sub>), the glottis (V55 and D<jats:sub>max<\/jats:sub>), the cricopharyngeal muscle (D<jats:sub>max<\/jats:sub>), and the cervical esophagus (D<jats:sub>max<\/jats:sub>).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We trained and cross-validated an\u00a0RID predictive model with high discriminative ability at both 6\u00a0and 12\u202fmonths after RT. We expect to improve the predictive power of this model by enlarging the number of training datasets.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00066-020-01697-7","type":"journal-article","created":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T12:02:53Z","timestamp":1602244973000},"page":"209-218","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Incorporating dose\u2013volume histogram parameters of swallowing organs at risk in a\u00a0videofluoroscopy-based predictive model of radiation-induced dysphagia after head and neck cancer intensity-modulated radiation therapy"],"prefix":"10.1007","volume":"197","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3018-2338","authenticated-orcid":false,"given":"Stefano","family":"Ursino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Giuliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio Di","family":"Martino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Cocuzza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Molinari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Stefanelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Giusti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Aringhieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Morganti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Neri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Traino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiola","family":"Paiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,9]]},"reference":[{"key":"1697_CR1","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1002\/hed.23246","volume":"36","author":"SS Batth","year":"2014","unstructured":"Batth\u00a0SS, Caudell\u00a0JJ, Chen\u00a0AM (2014) Practical considerations in reducing swallowing dysfunction following concurrent chemoradiotherapy with intensity-modulated radiotherapy for head and neck cancer. 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Strahlenther Onkol 196(6):522\u2013529. https:\/\/doi.org\/10.1007\/s00066-019-01572-0","journal-title":"Strahlenther Onkol"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-020-01697-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00066-020-01697-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-020-01697-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T05:44:46Z","timestamp":1633844686000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00066-020-01697-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,9]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["1697"],"URL":"https:\/\/doi.org\/10.1007\/s00066-020-01697-7","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,9]]},"assertion":[{"value":"7 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 September 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical guidelines"}},{"value":"Travel, congress, and course grants (Merck Serono, Nestl\u00e8, Kyowakirin, Astra Zeneca) have to be declared for S.\u00a0Ursino. Travel, congress, and course grants (Merck Serono, Nestl\u00e8, Kyowakirin, Varian, Astra Zeneca) have to be declared for F.\u00a0Paiar. A.\u00a0Giuliano, F.D.\u00a0Martino, P.\u00a0Cocuzza, A.\u00a0Molinari, A.\u00a0Stefanelli, P.\u00a0Giusti, G.\u00a0Aringhieri, R.\u00a0Morganti, E.\u00a0Neri, and C.\u00a0Traino declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. <i>Consent to participate:<\/i> informed consent was obtained from all individual participants included in the study. <i>Consent for publication:<\/i>\u00a0the authors affirm that human research participants consent for the publication of their data.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}