{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:31:04Z","timestamp":1793309464904,"version":"4.5.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T00:00:00Z","timestamp":1699574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T00:00:00Z","timestamp":1699574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100018936","name":"Universit\u00e4tsklinikum Heidelberg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100018936","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Mobile health (mhealth) is gaining interest, with mobile devices and apps being ever more available among medical facilities and patients. However, in the field of radiation oncology, the medical benefits of mhealth apps are still underexplored. As an additional approach to patient care during radiotherapy, we designed a\u00a0mobile treatment surveillance app based on patient-reported outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>We aimed to examine the feasibility of app-based treatment surveillance in patients undergoing radiotherapy (RT). Alongside technical practicability and acceptance, we assessed patient satisfaction and quality of life during treatment.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This prospective single-center study was performed at Heidelberg University Hospital between August 2018 and January 2020. During RT we measured patients\u2019 quality of life, symptoms, and treatment satisfaction. Respective questionnaires (EORTC QLQ-C30 with diagnosis-specific modules, RAND PSQ-18) were presented to patients via a\u00a0mobile app running on a\u00a0designated tablet device. The primary endpoint was determined by the fraction of patients who completed at least 80% of the items. Secondary endpoints were disease-related quality of life and patient satisfaction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 49\u00a0cancer patients (14\u00a0breast, 13\u00a0pelvic, 12\u00a0lung, 10\u00a0prostate) were eligible for analysis. 79.6% (95% confidence interval: 66.4\u201388.5%; <jats:italic>n<\/jats:italic>\u202f=\u200939) of all patients completed at least 80% of the items received by the mobile app. A\u00a0mean of 227.5\u202f\u00b1\u200948.25 questions were answered per patient. Breast cancer patients showed the highest rate of answered questions, with 92.9% (<jats:italic>n<\/jats:italic>\u202f=\u200913) completing at least 80% of the items.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Patients showed high acceptance, with 79.6% (<jats:italic>n<\/jats:italic>\u202f=\u200939) completing at least 80% of the given items. The use of a\u00a0mobile app for reporting symptoms and quality of life during RT is feasible and well accepted by patients. It may allow for resource-efficient, detailed feedback to the medical staff and assist in the assessment of side effects over time.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00066-023-02166-7","type":"journal-article","created":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T16:02:28Z","timestamp":1699632148000},"page":"475-486","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Oncologic treatment support via a\u00a0dedicated mobile app: a\u00a0prospective feasibility evaluation (OPTIMISE-1)"],"prefix":"10.1007","volume":"200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5598-7461","authenticated-orcid":false,"given":"Fabian A.","family":"Schunn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami A.","family":"El Shafie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothea","family":"Kronsteiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas D.","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kudak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Bougatf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"Oetzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Kr\u00e4mer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Regnery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Machmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Debus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils Henrik","family":"Nicolay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,10]]},"reference":[{"key":"2166_CR1","volume-title":"Number of mhealth apps available in the Apple app store from 1st\u00a0quarter 2015 to 3rd\u00a0quarter 2022","author":"L Ceci","year":"2022","unstructured":"Ceci\u00a0L, Statista (2022) Number of mhealth apps available in the Apple app store from 1st\u00a0quarter 2015 to 3rd\u00a0quarter 2022 (https:\/\/www.statista.com\/statistics\/779910\/health-apps-available-ios-worldwide\/)"},{"key":"2166_CR2","series-title":"Observatory","first-page":"66","volume-title":"mHealth: new horizons for health through mobile technologies","author":"World Health Organization","year":"2011","unstructured":"World Health Organization (2011) mHealth: new horizons for health through mobile technologies. 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J.\u00a0Debus received grants from CRI\u2014The Clinical Research Institute GmbH, View Ray Inc., Accuray International, Accuray Incorporated, RaySearch Laboratories AB, Vision RT limited, Astellas Pharma GmbH, Merck Serono GmbH, Astra Zeneca GmbH, Solution Akademie GmbH, Ergomed PLC Surrey Research Park, Siemens Healthcare GmbH, Quintiles GmbH, Pharmaceutical Research Associates GmbH, Boehringer Ingelheim Pharma GmbH Co, PTW-Freiburg Dr. Pychlau GmbH, Nanobiotix A.A., and IntraOP Medical outside the submitted work. N.H.\u00a0Nicolay received speaker honoraria from Merck and research grants from Novocure outside of the submitted work. F.A.\u00a0Schunn, D.\u00a0Kronsteiner, L.D.\u00a0Sauer, A.\u00a0Kudak, N.\u00a0Bougatf, D.\u00a0Oetzel, A.\u00a0Kr\u00e4mer, S.\u00a0Regnery, and T.\u00a0Machmer declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}