{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T11:31:56Z","timestamp":1788003116912,"version":"build-2784847793"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T00:00:00Z","timestamp":1726444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T00:00:00Z","timestamp":1726444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1007\/s00066-024-02296-6","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T12:02:35Z","timestamp":1726488155000},"page":"1047-1056","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The influence of different radiotherapy doses on the mechanical properties and microstructure of the enamel and dentin of human premolar teeth"],"prefix":"10.1007","volume":"200","author":[{"given":"Yuan","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yisi","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengge","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,16]]},"reference":[{"key":"2296_CR1","doi-asserted-by":"publisher","first-page":"E26","DOI":"10.1016\/j.anorl.2011.05.004","volume":"129","author":"X Dufour","year":"2012","unstructured":"Dufour\u00a0X, Beby-Defaux\u00a0A, Agius\u00a0G, Guily\u00a0StJL (2012) HPV and head and neck cancer. Eur Ann Otorhinolaryngol Head Neck Dis 129:E26\u2013E31. https:\/\/doi.org\/10.1016\/j.anorl.2011.05.004","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"key":"2296_CR2","doi-asserted-by":"publisher","first-page":"3277","DOI":"10.1200\/jco.2015.61.2994","volume":"33","author":"V Gr\u00e9goire","year":"2015","unstructured":"Gr\u00e9goire\u00a0V, Langendijk\u00a0JA, Nuyts\u00a0S (2015) Advances in radiotherapy for head and neck cancer. J\u00a0Clin Oncol 33:3277\u20133284. https:\/\/doi.org\/10.1200\/jco.2015.61.2994","journal-title":"J Clin Oncol"},{"key":"2296_CR3","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1476-4598-10-12","volume":"10","author":"R Wilken","year":"2011","unstructured":"Wilken\u00a0R, Veena\u00a0MS, Wang\u00a0MB, Srivatsan\u00a0ES (2011) Curcumin: a\u00a0review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma. Mol Cancer 10:12. https:\/\/doi.org\/10.1186\/1476-4598-10-12","journal-title":"Mol Cancer"},{"key":"2296_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jds.2015.09.003","volume":"11","author":"X Liang","year":"2016","unstructured":"Liang\u00a0X, Zhang\u00a0J, Peng\u00a0G, Li\u00a0J, Bai\u00a0S (2016) Radiation caries in nasopharyngeal carcinoma patients after intensity-modulated radiation therapy: a\u00a0cross-sectional study. J\u00a0Dent Sci 11:1\u20137. https:\/\/doi.org\/10.1016\/j.jds.2015.09.003","journal-title":"J Dent Sci"},{"key":"2296_CR5","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.critrevonc.2016.03.012","volume":"102","author":"M Buglione","year":"2016","unstructured":"Buglione\u00a0M, Cavagnini\u00a0R, Di Rosario\u00a0F, Maddalo\u00a0M, Vassalli\u00a0L, Grisanti\u00a0S et\u00a0al (2016) Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part\u00a02). Literature review and consensus statement. Crit Rev Oncol Hematol 102:47\u201354. https:\/\/doi.org\/10.1016\/j.critrevonc.2016.03.012","journal-title":"Crit Rev Oncol Hematol"},{"key":"2296_CR6","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1177\/154411130301400305","volume":"14","author":"A Vissink","year":"2003","unstructured":"Vissink\u00a0A, Jansma\u00a0J, Spijkervet\u00a0FKL, Burlage\u00a0FR, Coppes\u00a0RP (2003) Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med 14:199\u2013212. https:\/\/doi.org\/10.1177\/154411130301400305","journal-title":"Crit. Rev. Oral. Biol. Med."},{"key":"2296_CR7","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s00520-009-0633-3","volume":"18","author":"ARS Silva","year":"2010","unstructured":"Silva\u00a0ARS, Alves\u00a0FA, Berger\u00a0SB, Giannini\u00a0M, Goes\u00a0MF, Lopes\u00a0MA (2010) Radiation-related caries and early restoration failure in head and neck cancer patients. A\u00a0polarized light microscopy and scanning electron microscopy study. Support Care Cancer 18:83\u201387. https:\/\/doi.org\/10.1007\/s00520-009-0633-3","journal-title":"Support Care Cancer"},{"key":"2296_CR8","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/s1470-2045(06)70658-1","volume":"7","author":"AM Kielbassa","year":"2006","unstructured":"Kielbassa\u00a0AM, Hinkelbein\u00a0W, Hellwig\u00a0E, Meyer-Luckel\u00a0H (2006) Radiation-related damage to dentition. Lancet Oncol 7:326\u2013335. https:\/\/doi.org\/10.1016\/s1470-2045(06)70658-1","journal-title":"Lancet Oncol"},{"key":"2296_CR9","doi-asserted-by":"publisher","DOI":"10.1159\/000504878","author":"AF Gouv\u00eaa Vasconcellos","year":"2020","unstructured":"Gouv\u00eaa Vasconcellos\u00a0AF, Palmier\u00a0NR, Ribeiro\u00a0ACP, Normando AGC, Morais-Faria\u00a0K, Gomes-Silva\u00a0W et\u00a0al (2020) Impact of clustering oral symptoms in the pathogenesis of radiation caries: a\u00a0systematic review. Caries Res. https:\/\/doi.org\/10.1159\/000504878","journal-title":"Caries Res"},{"key":"2296_CR10","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1111\/j.1741-2358.2003.00064.x","volume":"20","author":"SF Cassolato","year":"2003","unstructured":"Cassolato\u00a0SF, Turnbull\u00a0RS (2003) Xerostomia: clinical aspects and treatment. Gerodontology 20:64\u201377. https:\/\/doi.org\/10.1111\/j.1741-2358.2003.00064.x","journal-title":"Gerodontology"},{"key":"2296_CR11","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/j.archoralbio.2015.02.020","volume":"60","author":"R Reed","year":"2015","unstructured":"Reed\u00a0R, Xu\u00a0C, Liu\u00a0Y, Gorski\u00a0JP, Wang\u00a0Y, Walker\u00a0MP (2015) Radiotherapy effect on nano-mechanical properties and chemical composition of enamel and dentine. Arch Oral Biol 60:690\u2013697. https:\/\/doi.org\/10.1016\/j.archoralbio.2015.02.020","journal-title":"Arch Oral Biol"},{"key":"2296_CR12","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.job.2019.10.002","volume":"61","author":"J Kudkuli","year":"2019","unstructured":"Kudkuli\u00a0J, Abdulla\u00a0R, Rekha\u00a0PD, Sharma\u00a0SD, Gurjar\u00a0O (2019) Spectroscopic analyses reveal radiotherapy-induced variations in elemental composition and crystallite properties of human permanent teeth enamel. J\u00a0Oral Biosci 61:207\u2013214. https:\/\/doi.org\/10.1016\/j.job.2019.10.002","journal-title":"J Oral Biosci"},{"key":"2296_CR13","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.archoralbio.2017.04.007","volume":"80","author":"SR de Barros da Cunha","year":"2017","unstructured":"de Barros da Cunha\u00a0SR, Fonseca\u00a0FP, Minorin Mendes Ramos\u00a0PA, Kalil Haddad\u00a0CM, Fregnani\u00a0ER, Aranha\u00a0ACC (2017) Effects of different radiation doses on the microhardness, superficial morphology, and mineral components of human enamel. Arch Oral Biol 80:130\u2013135. https:\/\/doi.org\/10.1016\/j.archoralbio.2017.04.007","journal-title":"Arch Oral Biol"},{"key":"2296_CR14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000192799","volume":"43","author":"ARS Silva","year":"2009","unstructured":"Silva\u00a0ARS, Alves\u00a0FA, Antunes\u00a0A, Goes\u00a0MF, Lopes\u00a0MA (2009) Patterns of demineralization and dentin reactions in radiation-related caries. Caries Res 43:43\u201349. https:\/\/doi.org\/10.1159\/000192799","journal-title":"Caries Res"},{"key":"2296_CR15","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.oraloncology.2015.06.009","volume":"51","author":"J Deng","year":"2015","unstructured":"Deng\u00a0J, Jackson\u00a0L, Epstein\u00a0JB, Migliorati\u00a0CA, Murphy\u00a0BA (2015) Dental demineralization and caries in patients with head and neck cancer. Oral Oncol 51:824\u2013831. https:\/\/doi.org\/10.1016\/j.oraloncology.2015.06.009","journal-title":"Oral Oncol"},{"key":"2296_CR16","doi-asserted-by":"publisher","first-page":"E80","DOI":"10.1016\/j.oraloncology.2009.03.005","volume":"45","author":"K Bekes","year":"2009","unstructured":"Bekes\u00a0K, Francke\u00a0U, Schaller\u00a0H\u2011G, Kuhnt\u00a0T, Gerlach\u00a0R, Vordermark\u00a0D et\u00a0al (2009) The influence of different irradiation doses and desensitizer application on demineralization of human dentin. Oral Oncol 45:E80\u2013E84. https:\/\/doi.org\/10.1016\/j.oraloncology.2009.03.005","journal-title":"Oral Oncol"},{"key":"2296_CR17","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/0300-5712(85)90061-2","volume":"13","author":"S Joystonbechal","year":"1985","unstructured":"Joystonbechal\u00a0S (1985) The effect of X\u2011radiation on the susceptibility of enamel to an artificial caries-like attack invitro. J\u00a0Dent 13:41\u201344. https:\/\/doi.org\/10.1016\/0300-5712(85)90061-2","journal-title":"J Dent"},{"key":"2296_CR18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.zemedi.2008.10.009","volume":"19","author":"W Fraenzel","year":"2009","unstructured":"Fraenzel\u00a0W, Gerlach\u00a0R (2009) The irradiation action on human dental tissue by X\u2011rays and electrons\u2014a\u00a0nanoindenter study. Z\u00a0Med Phys 19:5\u201310. https:\/\/doi.org\/10.1016\/j.zemedi.2008.10.009","journal-title":"Z Med Phys"},{"key":"2296_CR19","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1177\/039139880502800111","volume":"28","author":"W Hubner","year":"2005","unstructured":"Hubner\u00a0W, Blume\u00a0A, Pushjakova\u00a0R, Dekhtyar\u00a0Y, Hein\u00a0HJ (2005) The influence of X\u2011ray radiation on the mineral\/organic matrix interaction of bone tissue: an FT-IR microscopic investigation. Int J Artif Organs 28:66\u201373. https:\/\/doi.org\/10.1177\/039139880502800111","journal-title":"Int J Artif Organs"},{"key":"2296_CR20","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1002\/jbm.820270802","volume":"27","author":"M Panighi","year":"1993","unstructured":"Panighi\u00a0M, Gsell\u00a0C (1993) Effect of the tooth microstructure on the shear bond strength of a\u00a0dental composite. J\u00a0Biomed Mater Res 27:975\u2013981. https:\/\/doi.org\/10.1002\/jbm.820270802","journal-title":"J Biomed Mater Res"},{"key":"2296_CR21","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1590\/0103-6440201701190","volume":"28","author":"RD Nogueira","year":"2017","unstructured":"Nogueira\u00a0RD, Silva\u00a0CB, Lepri\u00a0CP, Palma-Dibb\u00a0RG, Geraldo-Martins\u00a0VR (2017) Evaluation of surface roughness and bacterial adhesion on tooth enamel irradiated with high intensity lasers. Braz Dent\u00a0J 28:24\u201329. https:\/\/doi.org\/10.1590\/0103-6440201701190","journal-title":"Braz Dent J"},{"key":"2296_CR22","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1177\/00220345750540040801","volume":"54","author":"LR Brown","year":"1975","unstructured":"Brown\u00a0LR, Dreizen\u00a0S, Handler\u00a0S, Johnston\u00a0DA (1975) Effect of radiation-induced xerostomia on human oral microflora. J\u00a0Dent Res 54:740\u2013750. https:\/\/doi.org\/10.1177\/00220345750540040801","journal-title":"J Dent Res"},{"key":"2296_CR23","doi-asserted-by":"publisher","first-page":"11568","DOI":"10.1038\/srep11568","volume":"5","author":"P Qing","year":"2015","unstructured":"Qing\u00a0P, Huang\u00a0S, Gao\u00a0S, Qian\u00a0L, Yu\u00a0H (2015) Effect of gamma irradiation on the wear behaviour of human tooth enamel. Sci Rep 5:11568. https:\/\/doi.org\/10.1038\/srep11568","journal-title":"Sci Rep"},{"key":"2296_CR24","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1159\/000261106","volume":"22","author":"J Jansma","year":"1988","unstructured":"Jansma\u00a0J, Buskes\u00a0JA, Vissink\u00a0A, Mehta\u00a0DM, Gravenmade\u00a0EJ (1988) The effect of X\u2011ray irradiation on the demineralization of bovine dental enamel. A\u00a0constant composition study. Caries Res 22:199\u2013203. https:\/\/doi.org\/10.1159\/000261106","journal-title":"Caries Res"},{"key":"2296_CR25","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1001\/archotol.1982.00790490023005","volume":"108","author":"DG Baker","year":"1982","unstructured":"Baker\u00a0DG (1982) The radiobiological basis for tissue reactions in the oral cavity following therapeutic x\u2011irradiation. A\u00a0review. Arch Otolaryngol 108:21\u201324. https:\/\/doi.org\/10.1001\/archotol.1982.00790490023005","journal-title":"Arch Otolaryngol"},{"key":"2296_CR26","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1002\/sca.20135","volume":"31","author":"S Ma","year":"2009","unstructured":"Ma\u00a0S, Cai\u00a0J, Zhan\u00a0X, Wu\u00a0Y (2009) Effects of Etchant on the nanostructure of dentin: an atomic force microscope study. Scanning 31:28\u201334. https:\/\/doi.org\/10.1002\/sca.20135","journal-title":"Scanning"},{"key":"2296_CR27","doi-asserted-by":"publisher","first-page":"4568","DOI":"10.1016\/j.msec.2013.07.014","volume":"33","author":"J Reyes-Gasga","year":"2013","unstructured":"Reyes-Gasga\u00a0J, Martinez-Pineiro\u00a0EL, Rodriguez-Alvarez\u00a0G, Tiznado-Orozco\u00a0GE, Garcia-Garcia\u00a0R, Bres\u00a0EF (2013) XRD and FTIR crystallinity indices in sound human tooth enamel and synthetic hydroxyapatite. Mater Sci Eng C Biomim Supramol Syst 33:4568\u20134574. https:\/\/doi.org\/10.1016\/j.msec.2013.07.014","journal-title":"Mater. Sci. Eng. C. Biomim. Supramol. Syst."},{"key":"2296_CR28","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1016\/j.jdent.2014.05.011","volume":"42","author":"LM Gon\u00e7alves","year":"2014","unstructured":"Gon\u00e7alves\u00a0LM, Palma-Dibb\u00a0RG, Paula-Silva\u00a0FW, Oliveira\u00a0HF, Nelson-Filho\u00a0P, Silva\u00a0LA et\u00a0al (2014) Radiation therapy alters microhardness and microstructure of enamel and dentin of permanent human teeth. J\u00a0Dent 42:986\u2013992. https:\/\/doi.org\/10.1016\/j.jdent.2014.05.011","journal-title":"J Dent"},{"key":"2296_CR29","doi-asserted-by":"publisher","first-page":"E96","DOI":"10.4317\/medoral.23212","volume":"25","author":"JM Fonseca","year":"2020","unstructured":"Fonseca\u00a0JM, Madrid Troconis\u00a0CC, Palmier\u00a0NR, Gomes-Silva\u00a0W, Paglioni\u00a0M, Damaceno Araujo\u00a0AL et\u00a0al (2020) The impact of head and neck radiotherapy on the dentine-enamel junction: a\u00a0systematic review. Med Oral Patol Oral Cir Bucal 25:E96\u2013E105. https:\/\/doi.org\/10.4317\/medoral.23212","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"2296_CR30","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1159\/000452866","volume":"51","author":"CC Madrid","year":"2017","unstructured":"Madrid\u00a0CC, de Pauli Paglioni\u00a0M, Line\u00a0SR, Vasconcelos\u00a0KG, Brand\u00e3o\u00a0TB, Lopes\u00a0MA et\u00a0al (2017) Structural analysis of enamel in teeth from head-and-neck cancer patients who underwent radiotherapy. Caries Res 51:119\u2013128. https:\/\/doi.org\/10.1159\/000452866","journal-title":"Caries Res"},{"key":"2296_CR31","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s00223-001-2012-z","volume":"69","author":"W Tesch","year":"2001","unstructured":"Tesch\u00a0W, Eidelman\u00a0N, Roschger\u00a0P, Goldenberg\u00a0F, Klaushofer\u00a0K, Fratzl\u00a0P (2001) Graded microstructure and mechanical properties of human crown dentin. Calcif Tissue Int 69:147\u2013157. https:\/\/doi.org\/10.1007\/s00223-001-2012-z","journal-title":"Calcif Tissue Int"},{"key":"2296_CR32","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s100060050035","volume":"2","author":"KA Grotz","year":"1998","unstructured":"Grotz\u00a0KA, Duschner\u00a0H, Kutzner\u00a0J, Thelen\u00a0M, Wagner\u00a0W (1998) Histotomography studies of direct radiogenic dental enamel changes. Mund Kiefer Gesichtschir 2:85\u201390. https:\/\/doi.org\/10.1007\/s100060050035","journal-title":"Mund Kiefer Gesichtschir"},{"key":"2296_CR33","doi-asserted-by":"publisher","first-page":"3644","DOI":"10.1021\/acsbiomaterials.2c00287","volume":"8","author":"D Viswanath","year":"2022","unstructured":"Viswanath\u00a0D, Won\u00a0YY et\u00a0al (2022) Combining radiotherapy (RT) and photodynamic therapy (PDT): clinical studies on conventional RT-PDT approaches and novel nanoparticle-based RT-PDT approaches under preclinical evaluation. ACS Biomater Sci Eng 8:3644\u20133658. https:\/\/doi.org\/10.1021\/acsbiomaterials.2c00287","journal-title":"ACS Biomater Sci Eng"},{"key":"2296_CR34","doi-asserted-by":"publisher","first-page":"612","DOI":"10.4103\/jcrt.JCRT_8_19","volume":"16","author":"J Kudkuli","year":"2020","unstructured":"Kudkuli\u00a0J, Agrawal\u00a0A, Gurjar\u00a0OP, Sharma\u00a0SD, Rekha\u00a0PD, Manzoor\u00a0MAP et\u00a0al (2020) Demineralization of tooth enamel following radiation therapy; an in vitro microstructure and microhardness analysis. J\u00a0Cancer Res Ther 16:612\u2013618. https:\/\/doi.org\/10.4103\/jcrt.JCRT_8_19","journal-title":"J Cancer Res Ther"},{"key":"2296_CR35","doi-asserted-by":"publisher","first-page":"334","DOI":"10.15644\/asc55\/4\/1","volume":"55","author":"EK Sever","year":"2021","unstructured":"Sever\u00a0EK, Tarle\u00a0A, Vukelja\u00a0J, Soce\u00a0M, Grego\u00a0T et\u00a0al (2021) Direct induced effects of standard and modified radiotherapy protocol on surface structure of hard dental tissue. Acta Stomatol Croat 55:334\u2013345. https:\/\/doi.org\/10.15644\/asc55\/4\/1","journal-title":"Acta Stomatol Croat"},{"key":"2296_CR36","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/s0003-9969(98)00123-x","volume":"44","author":"AM Kielbassa","year":"1999","unstructured":"Kielbassa\u00a0AM, Wrbas\u00a0KT, Schulte-Monting\u00a0J, Hellwig\u00a0E (1999) Correlation of transversal microradiography and microhardness on in situ-induced demineralization in irradiated and nonirradiated human dental enamel. Arch Oral Biol 44:243\u2013251. https:\/\/doi.org\/10.1016\/s0003-9969(98)00123-x","journal-title":"Arch Oral Biol"},{"key":"2296_CR37","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1159\/000016568","volume":"34","author":"AM Kielbassa","year":"2000","unstructured":"Kielbassa\u00a0AM, Schendera\u00a0A, Schulte-Monting\u00a0J (2000) Microradiographic and microscopic studies on in situ induced initial caries in irradiated and nonirradiated dental enamel. Caries Res 34:41\u201347. https:\/\/doi.org\/10.1159\/000016568","journal-title":"Caries Res"},{"key":"2296_CR38","doi-asserted-by":"publisher","first-page":"151","DOI":"10.3290\/j.jad.a35841","volume":"18","author":"SR de Barros da Cunha","year":"2016","unstructured":"de Barros da Cunha\u00a0SR, Minorin Mendes Ramos\u00a0PA, Kalil Haddad\u00a0CM, Fernandes da Silva\u00a0JL, Fregnani\u00a0ER, Aranha\u00a0ACC (2016) Effects of different radiation doses on the bond strengths of two different adhesive systems to enamel and dentin. J\u00a0Adhes Dent 18:151\u2013156. https:\/\/doi.org\/10.3290\/j.jad.a35841","journal-title":"J Adhes Dent"},{"key":"2296_CR39","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1159\/000261260","volume":"24","author":"J Jansma","year":"1990","unstructured":"Jansma\u00a0J, Borggreven\u00a0JM, Driessens\u00a0FC, s\u2011Gravenmade EJ (1990) Effect of X\u2011ray irradiation on the permeability of bovine dental enamel. Caries Res 24:164\u2013168. https:\/\/doi.org\/10.1159\/000261260","journal-title":"Caries Res"},{"key":"2296_CR40","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1177\/0022034509351251","volume":"89","author":"CJ Soares","year":"2010","unstructured":"Soares\u00a0CJ, Castro\u00a0CG, Neiva\u00a0NA, Soares\u00a0PV, Santos-Filho\u00a0PC, Naves\u00a0LZ et\u00a0al (2010) Effect of gamma irradiation on ultimate tensile strength of enamel and dentin. J\u00a0Dent Res 89:159\u2013164. https:\/\/doi.org\/10.1177\/0022034509351251","journal-title":"J Dent Res"},{"key":"2296_CR41","doi-asserted-by":"publisher","first-page":"160","DOI":"10.4103\/0975-5950.183870","volume":"6","author":"N Gupta","year":"2015","unstructured":"Gupta\u00a0N, Pal\u00a0M, Rawat\u00a0S, Grewal\u00a0MS, Garg\u00a0H, Chauhan\u00a0D et\u00a0al (2015) Radiation-induced dental caries, prevention and treatment\u2014a systematic review. Natl J Maxillofac Surg 6:160\u2013166. https:\/\/doi.org\/10.4103\/0975-5950.183870","journal-title":"Natl J Maxillofac Surg"},{"key":"2296_CR42","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s00411-017-0690-9","volume":"56","author":"R Abdalla","year":"2017","unstructured":"Abdalla\u00a0R, Niazy\u00a0MA, Jamil\u00a0WE, Hazzaa\u00a0HA, Elbatouti\u00a0AA (2017) The role of fluoride and chlorhexidine in preserving hardness and mineralization of enamel and cementum after gamma irradiation. Radiat Environ Biophys 56:187\u2013192. https:\/\/doi.org\/10.1007\/s00411-017-0690-9","journal-title":"Radiat Environ Biophys"},{"key":"2296_CR43","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1111\/iej.13252","volume":"53","author":"FC Lopes","year":"2020","unstructured":"Lopes\u00a0FC, Roperto\u00a0R, Akkus\u00a0A, de Queiroz\u00a0AM, Francisco de Oliveira\u00a0H, Sousa-Neto\u00a0MD (2020) Effect of carbodiimide and chlorhexidine on the bond strength longevity of resin cement to root dentine after radiation therapy. Int Endod\u00a0J 53:539\u2013552. https:\/\/doi.org\/10.1111\/iej.13252","journal-title":"Int Endod J"},{"key":"2296_CR44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2020.103429","author":"SR Cunha","year":"2020","unstructured":"Cunha\u00a0SR, Maravic\u00a0T, Comba\u00a0A, Ramos\u00a0PA, Tay\u00a0FR, Pashley\u00a0DH et\u00a0al (2020) In vivo and in vitro radiotherapy increased dentin enzymatic activity. J\u00a0Dent. https:\/\/doi.org\/10.1016\/j.jdent.2020.103429","journal-title":"J Dent"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-024-02296-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00066-024-02296-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-024-02296-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T13:02:34Z","timestamp":1732539754000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00066-024-02296-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,16]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["2296"],"URL":"https:\/\/doi.org\/10.1007\/s00066-024-02296-6","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,16]]},"assertion":[{"value":"29 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Y.\u00a0Tu, L.\u00a0Hao, Y.\u00a0Ding, Y.\u00a0Zhong, C.\u00a0Hua, and L.\u00a0Jiang declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Ethics Committee of the West China College of Stomatology, Sichuan University (WCHSIRB-D-2019-224). No patient information was revealed, and individual patient records were de-identified before being included in the present analysis. For the above reasons, informed consent from the patients was not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}