{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T21:31:35Z","timestamp":1781213495612,"version":"3.54.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Bursa Uludag University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The aim is to evaluate treatment outcomes and prognostic factors in patients with thymic epithelial tumor (TET) treated with radiotherapy (RT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixty-four patients were treated between 2000 and 2023. The median age was 52\u00a0years (20\u201383), and 81% of underwent R0 resection. The stage\u00a0(s) distribution for\u00a0I, II, III, and\u00a0IV were 5%, 61%, 26%, and 8% by Masaoka-Koga and 63%, 11%, 17%, and 9% by TNM, respectively. WHO types\u00a0A\/AB\/B\/C and thymic neuroendocrine tumors were seen in 5%, 22%, 64%, 6%, and 3% of patients, respectively. The median RT dose was 5040 cGy (1620\u20136596). Survival was calculated from the beginning of RT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median follow-up was 70\u00a0months (1.5\u2013268). The median time to recurrence was 30\u00a0months (6.5\u2013106), seen in 23% of patients. Mean overall (OS), progression-free survival (PFS) and 5\u2011year local control were 141, 138\u00a0months, and 82.4%, respectively. In univariate analysis, the presence of organ invasion and TNM stage were significant as new prognostic factors for survival (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&lt;\u20090.05). In multivariate analysis, the high-risk group (B2\/B3\/C) and another surgical center (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&lt;\u20090.05) for OS, and KPS\u202f\u2264\u200980, thymic carcinoma, and Masaoka-Koga sIII-IV (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&lt;\u20090.05) for PFS were identified as unfavorable prognostic factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Recurrence in TET can occur over a\u00a0longer period. In this study, 5\u2011year local control of 82.4% was achieved. The prognostic importance of KPS, histology, Masaoka-Koga stage, risk group, and surgical center was demonstrated. Advances in the diagnosis, staging, and treatment of TET will enable more personalized treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00066-025-02395-y","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T05:53:36Z","timestamp":1745387616000},"page":"1259-1268","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thymic tumors: radiotherapy experience for single institute"],"prefix":"10.1007","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4816-5798","authenticated-orcid":false,"given":"Sureyya","family":"Sarihan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4260-3937","authenticated-orcid":false,"given":"Aybuke Tugce","family":"Metin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0684-0900","authenticated-orcid":false,"given":"Ahmet Sami","family":"Bayram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9887-6320","authenticated-orcid":false,"given":"Huseyin","family":"Melek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"issue":"Suppl 5","key":"2395_CR1","doi-asserted-by":"publisher","first-page":"v40","DOI":"10.1093\/annonc\/mdv277","volume":"26","author":"N Girard","year":"2015","unstructured":"Girard\u00a0N, Ruffini\u00a0E, Marx\u00a0A, Faivre-Finn\u00a0C, Peters\u00a0S, Guidelines Committee\u00a0ESMO (2015) Thymic epithelial tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up. Ann Oncol 26(Suppl 5):v40\u2013v55. https:\/\/doi.org\/10.1093\/annonc\/mdv277","journal-title":"Ann Oncol"},{"key":"2395_CR2","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1007\/s00595-023-02705-w","volume":"53","author":"M Okumura","year":"2023","unstructured":"Okumura\u00a0M, Yoshino\u00a0I, Funaki\u00a0S, Okuda\u00a0K, Watanabe\u00a0SI, Tsuboi\u00a0M et\u00a0al (2023) Long-term outcomes following surgical treatment for a\u00a0thymic epithelial tumor in Japan and analysis of prognostic factors based on the Japanese association for research on the thymus nationwide database. Surg Today 53:1247\u20131259. https:\/\/doi.org\/10.1007\/s00595-023-02705-w","journal-title":"Surg Today"},{"issue":"4","key":"2395_CR3","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1007\/s12094-022-02788-w","volume":"24","author":"J Remon","year":"2022","unstructured":"Remon\u00a0J, Bernabe\u00a0R, Diz\u00a0P, Felip\u00a0E, Gonzalez-Larriba\u00a0JL, Lazaro\u00a0M et\u00a0al (2022) Seom-Gecp-Getth\u0131 Clinical Guidelines for the treatment of patients with thymic epithelial tumours. Clin Trans Oncol 24(4):635\u2013645. https:\/\/doi.org\/10.1007\/s12094-022-02788-w","journal-title":"Clin Trans Oncol"},{"issue":"2","key":"2395_CR4","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.jtho.2021.10.010","volume":"17","author":"A Marx","year":"2022","unstructured":"Marx\u00a0A, Chan\u00a0JKC, Chabresse\u00a0L, Dacic\u00a0S, Detterbeck\u00a0F, French\u00a0CA et\u00a0al (2022) The 2021 WHO classification of tumors of the thymus and mediastinum: What is new in thymic epithelial, germ cell, and mesenchymal tumors? J\u00a0Thorac Oncol 17(2):200\u2013213. https:\/\/doi.org\/10.1016\/j.jtho.2021.10.010","journal-title":"J Thorac Oncol"},{"issue":"11","key":"2395_CR5","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1016\/j.jtho.2017.07.023","volume":"12","author":"C Basse","year":"2017","unstructured":"Basse\u00a0C, Thureau\u00a0S, Bota\u00a0S, Dansin\u00a0E, Thomas\u00a0PA, Pichon\u00a0E et\u00a0al (2017) Multidisciplinary tumor board decision making for postoperative radiotherapy in thymic epithelial tumours: Insights from the Rythm\u0131c prospective cohort. J\u00a0Thorac Oncol 12(11):1715\u20131722. https:\/\/doi.org\/10.1016\/j.jtho.2017.07.023","journal-title":"J Thorac Oncol"},{"issue":"3","key":"2395_CR6","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.jtho.2017.11.118","volume":"13","author":"SK Padda","year":"2018","unstructured":"Padda\u00a0SK, Yao\u00a0X, Antonicelli\u00a0A, Riess\u00a0JW, Shang\u00a0Y, Shrager\u00a0JB et\u00a0al (2018) Paraneoplastic syndromes and thymic malignancies: an examination of the International Thymic Malignancy Interest Group retrospective database. J\u00a0Thorac Oncol 13(3):436\u2013446. https:\/\/doi.org\/10.1016\/j.jtho.2017.11.118","journal-title":"J Thorac Oncol"},{"issue":"39","key":"2395_CR7","doi-asserted-by":"publisher","first-page":"e30867","DOI":"10.1097\/MD.0000000000030867","volume":"101","author":"J Li","year":"2022","unstructured":"Li\u00a0J, Liu\u00a0Y, Zhang\u00a0X, Zheng\u00a0X, Qi\u00a0G (2022) Prognostic factors for overall survival after surgical resection in patients with thymic epithelial tumors: A\u00a0systematic review and meta-analysis. Medicine 101(39):e30867. https:\/\/doi.org\/10.1097\/MD.0000000000030867","journal-title":"Medicine"},{"issue":"8","key":"2395_CR8","doi-asserted-by":"publisher","first-page":"4900","DOI":"10.1245\/s10434-022-11698-8","volume":"29","author":"S Funaki","year":"2022","unstructured":"Funaki\u00a0S, Ose\u00a0N, Kanou\u00a0T, Fukui\u00a0E, Kimura\u00a0K, Minami\u00a0M et\u00a0al (2022) Prognostic impact of number of organ invasions in patients with surgically resected thymoma. Ann Surg Oncol 29(8):4900\u20134907. https:\/\/doi.org\/10.1245\/s10434-022-11698-8","journal-title":"Ann Surg Oncol"},{"key":"2395_CR9","doi-asserted-by":"publisher","first-page":"110272","DOI":"10.1016\/j.radonc.2024.110272","volume":"195","author":"H Lopez","year":"2024","unstructured":"Lopez\u00a0H, Botticella\u00a0A, Belkhir\u00a0F, Besse\u00a0B, Fadel\u00a0E, Mercier\u00a0O et\u00a0al (2024) Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10\u00a0years of follow-up. Radiother Oncol 195:110272. https:\/\/doi.org\/10.1016\/j.radonc.2024.110272","journal-title":"Radiother Oncol"},{"issue":"7 Suppl 3","key":"2395_CR10","doi-asserted-by":"publisher","first-page":"S1710","DOI":"10.1097\/JTO.0b013e31821e8cff","volume":"6","author":"FC Detterbeck","year":"2011","unstructured":"Detterbeck\u00a0FC, Nicholson\u00a0AG, Kondo\u00a0K, van Schil\u00a0P, Moran\u00a0C (2011) The Masaoka-Koga stage classification for thymic malignancies: clarification and definition of terms. J\u00a0Thorac Oncol 6(7 Suppl 3):S1710\u2013S1716. https:\/\/doi.org\/10.1097\/JTO.0b013e31821e8cff","journal-title":"J Thorac Oncol"},{"issue":"9 Suppl 2","key":"2395_CR11","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1097\/JTO.0000000000000290","volume":"9","author":"FC Detterbeck","year":"2014","unstructured":"Detterbeck\u00a0FC, Stratton\u00a0K, Giroux\u00a0D, Asamura\u00a0H, Crowley\u00a0J, Falkson\u00a0C et\u00a0al (2014) The Iaslc\/ITMIG Thymic epithelial tumors staging project: proposal for an evidence-based stage classification system for the forthcoming (8th) edition of the TNM classification of malignant tumors. J\u00a0Thorac Oncol 9(9 Suppl 2):65\u201372. https:\/\/doi.org\/10.1097\/JTO.0000000000000290","journal-title":"J Thorac Oncol"},{"issue":"8","key":"2395_CR12","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1002\/jso.25462","volume":"119","author":"J Yun","year":"2019","unstructured":"Yun\u00a0J, Lee\u00a0GD, Kim\u00a0HY, Kim\u00a0DK, Zo\u00a0JI, Shim\u00a0YM et\u00a0al (2019) A nomogram for predicting recurrence after complete resection for thymic epithelial tumors based on the TNM classification: a\u00a0multi-institutional retrospective analysis. J\u00a0Surg Oncol 119(8):1181\u20131169. https:\/\/doi.org\/10.1002\/jso.25462","journal-title":"J Surg Oncol"},{"issue":"10","key":"2395_CR13","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1016\/j.jtho.2016.06.011","volume":"11","author":"A Rimner","year":"2016","unstructured":"Rimner\u00a0A, Yao\u00a0X, Huang\u00a0J, Antonicelli\u00a0A, Ahmad\u00a0U, Korst\u00a0R et\u00a0al (2016) Postoperative radiation therapy is associated with longer overall survival in completely resected stage\u00a0II and\u00a0III thymoma-An analysis of the International Thymic Malignancies Interest Group retrospective database. J\u00a0Thorac Oncol 11(10):1785\u20131792. https:\/\/doi.org\/10.1016\/j.jtho.2016.06.011","journal-title":"J Thorac Oncol"},{"issue":"4","key":"2395_CR14","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.jtho.2020.12.023","volume":"16","author":"Y Tateishi","year":"2021","unstructured":"Tateishi\u00a0Y, Horita\u00a0N, Namkoong\u00a0H, Enomoto\u00a0T, Takeda\u00a0A, Kaneko\u00a0T (2021) Postoperative radiotherapy for completely resected Masaoka\/Masaoka-Koga stage\u00a0II\/III thymoma improves overall survival: An update meta-analysis of 4746 patients. J\u00a0Thorac Oncol 16(4):677\u2013685. https:\/\/doi.org\/10.1016\/j.jtho.2020.12.023","journal-title":"J Thorac Oncol"},{"issue":"4","key":"2395_CR15","doi-asserted-by":"publisher","first-page":"e0283192","DOI":"10.1371\/journal.pone.0283192","volume":"18","author":"LM Lin","year":"2023","unstructured":"Lin\u00a0LM, Li\u00a0YM, Huang\u00a0YX, Zhang\u00a0ZK, Dai\u00a0YQ, Liu\u00a0J, Lin\u00a0Q (2023) Evaluation of the role of postoperative radiotherapy in locally invasive thymoma: A\u00a0propensity-matched study based on the SEER database. PLoS ONE 18(4):e283192. https:\/\/doi.org\/10.1371\/journal.pone.0283192","journal-title":"PLoS ONE"},{"issue":"4","key":"2395_CR16","doi-asserted-by":"publisher","first-page":"2088","DOI":"10.21037\/tlcr-20-458","volume":"10","author":"K S\u00fcveg","year":"2021","unstructured":"S\u00fcveg\u00a0K, Putora\u00a0PM, Joerger\u00a0M, Iseli\u00a0T, Fischer\u00a0GF, Ammann\u00a0K, Glatzer\u00a0M (2021) Radiotherapy for thymic epithelial tumours: a\u00a0review. Transl Lung Cancer Res 10(4):2088\u20132100. https:\/\/doi.org\/10.21037\/tlcr-20-458","journal-title":"Transl Lung Cancer Res"},{"issue":"7","key":"2395_CR17","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1016\/j.jtho.2024.04.003","volume":"19","author":"C Basse","year":"2024","unstructured":"Basse\u00a0C, Khalifa\u00a0J, Thillays\u00a0F, Le Pechoux\u00a0C, Maury\u00a0JM, Bonte\u00a0PE et\u00a0al (2024) Recommendations for post-operative radiotherapy after complete resection of thymoma\u2014a\u00a0French DELPHI consensus initiative. J\u00a0Thorac Oncol 19(7):1095\u20131107. https:\/\/doi.org\/10.1016\/j.jtho.2024.04.003","journal-title":"J Thorac Oncol"},{"issue":"1","key":"2395_CR18","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jtho.2023.09.1447","volume":"19","author":"W Fang","year":"2023","unstructured":"Fang\u00a0W, Girard\u00a0N, Cilento\u00a0V, Goren\u00a0E, Dibaba\u00a0D, Ruffini\u00a0E et\u00a0al (2023) The international association for the study of lung cancer thymic epithelial tumors staging project: proposals for the N and the M components for the forthcoming (ninth) edition of the TNM classification of malignant tumors. J\u00a0Thorac Oncol 19(1):52\u201370. https:\/\/doi.org\/10.1016\/j.jtho.2023.09.1447","journal-title":"J Thorac Oncol"},{"issue":"5","key":"2395_CR19","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1111\/his.14167","volume":"77","author":"JL Wolf","year":"2020","unstructured":"Wolf\u00a0JL, van Nederveen\u00a0F, Blaauwgeers\u00a0H, Marx\u00a0A, Nicholson\u00a0AG, Roden\u00a0AC et\u00a0al (2020) Interobserver variation in the classification of thymic lesions including biopsies and resection specimens in an international digital microscopy panel. Histopathology 77(5):734\u2013741. https:\/\/doi.org\/10.1111\/his.14167","journal-title":"Histopathology"},{"issue":"5","key":"2395_CR20","doi-asserted-by":"publisher","first-page":"901","DOI":"10.21037\/jtd.2016.03.53","volume":"8","author":"GD Lee","year":"2016","unstructured":"Lee\u00a0GD, Kim\u00a0HY, Choi\u00a0YH, Kim\u00a0DK, Park\u00a0SI (2016) Prognostic stratification of thymic epithelial tumors based on both Masaoka-Koga stage and WHO classification systems. J\u00a0Thorac Dis 8(5):901\u2013910. https:\/\/doi.org\/10.21037\/jtd.2016.03.53","journal-title":"J Thorac Dis"},{"issue":"4","key":"2395_CR21","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1016\/j.jtho.2017.01.002","volume":"12","author":"MW Jackson","year":"2017","unstructured":"Jackson\u00a0MW, Palma\u00a0DA, Camidge\u00a0DR, Jones\u00a0BL, Robin\u00a0TP, Sher\u00a0DJ et\u00a0al (2017) The impact of postoperative radiotherapy for thymoma and thymic carcinoma. J\u00a0Thorac Oncol 12(4):734\u2013744. https:\/\/doi.org\/10.1016\/j.jtho.2017.01.002","journal-title":"J Thorac Oncol"},{"issue":"19","key":"2395_CR22","doi-asserted-by":"publisher","first-page":"e37956","DOI":"10.1097\/MD.0000000000037956","volume":"103","author":"Y Shi","year":"2024","unstructured":"Shi\u00a0Y, Chen\u00a0H, Luo\u00a0S, Xiong\u00a0J, Xiong\u00a0L, Yu\u00a0D (2024) Postoperative radiotherapy does not improve survival in patients with Masaoka-Koga stage IIB thymomas: A\u00a0propensity score matching study based on the SEER database. Medicine 103(19):e37956. https:\/\/doi.org\/10.1097\/MD.0000000000037956","journal-title":"Medicine"},{"key":"2395_CR23","doi-asserted-by":"publisher","first-page":"1136166","DOI":"10.3389\/fsurg.2023.1136166","volume":"10","author":"Y Li","year":"2023","unstructured":"Li\u00a0Y, Tang\u00a0Z, Zhu\u00a0X, Tian\u00a0H (2023) Nomogram based on TNM stage to predict the prognosis of thymic epithelial tumors (TETs) patients undergoing extended thymectomy. Front Surg 10:1136166. https:\/\/doi.org\/10.3389\/fsurg.2023.1136166","journal-title":"Front Surg"},{"key":"2395_CR24","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.ctrv.2018.10.001","volume":"71","author":"M Imbimbo","year":"2018","unstructured":"Imbimbo\u00a0M, Ottaviano\u00a0M, Vitali\u00a0M, Fabbri\u00a0A, Leuzzi\u00a0G, Fiore\u00a0M et\u00a0al (2018) Best practice for the management of thymic epithelial tumors: a\u00a0position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME). Cancer Treat Rev 71:76\u201387. https:\/\/doi.org\/10.1016\/j.ctrv.2018.10.001","journal-title":"Cancer Treat Rev"},{"issue":"4","key":"2395_CR25","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/j.jtho.2023.12.011","volume":"19","author":"A Rimner","year":"2024","unstructured":"Rimner\u00a0A, Ahmad\u00a0U, Lobaugh\u00a0SM, Zhang\u00a0Z, Shepherd\u00a0AF, Huang\u00a0J et\u00a0al (2024) Postoperative radiation therapy for thymic carcinoma: an analysis of the International Thymic Malignancy Interest Group\/European Society of Thoracic Surgeons Database. J\u00a0Thorac Oncol 19(4):626\u2013635. https:\/\/doi.org\/10.1016\/j.jtho.2023.12.011","journal-title":"J Thorac Oncol"},{"issue":"3","key":"2395_CR26","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1177\/03008916221109334","volume":"109","author":"YY Huang","year":"2023","unstructured":"Huang\u00a0YY, Liu\u00a0X, Liang\u00a0SH, Wu\u00a0LL, Ma\u00a0GW (2023) Nomogram predicts the prognosis of patients with thymic carcinoma: a\u00a0population-based study using SEER data. Tumori 109(3):282\u2013294. https:\/\/doi.org\/10.1177\/03008916221109334","journal-title":"Tumori"},{"issue":"12","key":"2395_CR27","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1016\/j.jtho.2023.09.002","volume":"18","author":"E Ruffini","year":"2023","unstructured":"Ruffini\u00a0E, Huang\u00a0J, Cilento\u00a0V, Goren\u00a0E, Detterbeck\u00a0F, Ahmad\u00a0U et\u00a0al (2023) The international association for the study of lung cancer thymic epithelial tumors staging project: proposal for a\u00a0stage classification for the forthcoming (ninth) edition of the TNM classification of malignant tumors. J\u00a0Thorac Oncol 18(12):1655\u20131671. https:\/\/doi.org\/10.1016\/j.jtho.2023.09.002","journal-title":"J Thorac Oncol"},{"key":"2395_CR28","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.critrevonc.2016.01.012","volume":"99","author":"M Scorsetti","year":"2016","unstructured":"Scorsetti\u00a0M, Leo\u00a0F, Trama\u00a0A, D\u2019Angelillo\u00a0R, Serpico\u00a0D, Macerelli\u00a0M et\u00a0al (2016) Thymoma and thymic carcinomas. Crit Rev Oncol Hematol 99:332\u2013350. https:\/\/doi.org\/10.1016\/j.critrevonc.2016.01.012","journal-title":"Crit Rev Oncol Hematol"},{"issue":"4","key":"2395_CR29","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.21037\/jtd.2019.02.90","volume":"11","author":"TY Shi","year":"2019","unstructured":"Shi\u00a0TY, Wen\u00a0XH, Shi\u00a0XH, Lu\u00a0YW (2019) Thymic epithelial tumor complicated by immunological abnormalities: results from a\u00a0single-center retrospective study in China. J\u00a0Thorac Dis 11(4):1580\u20131588. https:\/\/doi.org\/10.21037\/jtd.2019.02.90","journal-title":"J Thorac Dis"},{"issue":"7 Suppl 3","key":"2395_CR30","doi-asserted-by":"publisher","first-page":"S1743","DOI":"10.1097\/JTO.0b013e31821ea60c","volume":"6","author":"D Gomez","year":"2011","unstructured":"Gomez\u00a0D, Komaki\u00a0R, Yu\u00a0J, Ikushima\u00a0H, Bezjak\u00a0A (2011) Radiation therapy definitions and reporting guidelines for thymic malignancies. Thorac Oncol 6(7 Suppl 3):S1743\u2013S1748. https:\/\/doi.org\/10.1097\/JTO.0b013e31821ea60c","journal-title":"Thorac Oncol"},{"issue":"7","key":"2395_CR31","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.3390\/cancers15071953","volume":"15","author":"Y Zhang","year":"2023","unstructured":"Zhang\u00a0Y, Lin\u00a0D, Aramini\u00a0B, Yang\u00a0F, Chen\u00a0X, Wang\u00a0X et\u00a0al (2023) Thymoma and thymic carcinoma: surgical resection and multidisciplinary treatment. Cancers 15(7):1953. https:\/\/doi.org\/10.3390\/cancers15071953","journal-title":"Cancers"},{"issue":"1","key":"2395_CR32","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1186\/s12880-024-01367-5","volume":"24","author":"C Gao","year":"2024","unstructured":"Gao\u00a0C, Yang\u00a0L, Xu\u00a0Y, Wang\u00a0T, Ding\u00a0H, Gao\u00a0X, Li\u00a0L (2024) Differentiating low-risk thymomas from high-risk thymomas: preoperative radiomics nomogram based on contrast-enhanced CT to minimize unnecessary invasive thoracotomy. BMC Med Imaging 24(1):197. https:\/\/doi.org\/10.1186\/s12880-024-01367-5","journal-title":"BMC Med Imaging"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-025-02395-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00066-025-02395-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-025-02395-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T12:52:25Z","timestamp":1765543945000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00066-025-02395-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,23]]},"references-count":32,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["2395"],"URL":"https:\/\/doi.org\/10.1007\/s00066-025-02395-y","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"value":"0179-7158","type":"print"},{"value":"1439-099X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,23]]},"assertion":[{"value":"16 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"S.\u00a0Sarihan, A.T.\u00a0Metin, A.S.\u00a0Bayram and H.\u00a0Melek declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was concucted in accordance by the Declaration of Helsinki. Local ethical committee of Bursa Uludag University approval was granted (2024-14\/9). Informed consent was obtained from all patients included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}