{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:13:14Z","timestamp":1761181994869,"version":"build-2065373602"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Open Access Publication Fund of the University of M\u00fcnster"},{"name":"Universit\u00e4tsklinikum M\u00fcnster"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Strahlenther Onkol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Positron-emission tomography combined with computed tomography (PET\/CT) is the diagnostic standard for patients with Hodgkin\u2019s lymphoma. Positron-emission tomography combined with magnetic resonance imaging (PET\/MRI) is an alternative diagnostic modality that reduces radiation exposure to the patient. This study aims to evaluate the potential merits of PET\/MRI compared to PET\/CT for target delineation for radiotherapy of Hodgkin\u2019s lymphoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Five patients with newly diagnosed Hodgkin\u2019s lymphoma underwent PET\/CT imaging directly followed by PET\/MRI imaging as part of initial staging. Both modalities were subsequently compared regarding each patient\u2019s diagnosed involved nodal regions. Three of these patients received radiotherapy after the completion of chemotherapy. In the radiotherapy planning CT, different gross tumor volumes and clinical target volumes were contoured for both PET\/CT and PET\/MRI and quantitatively compared using the Dice coefficient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No differences regarding the diagnosed disease stage were observed. The delineated tumor and target volumes showed minor differences without clinical significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Positron-emission tomography\/MRI is a\u00a0viable option to assure adequate staging and later target delineation in patients with Hodgkin\u2019s lymphoma. Due to the reduction of radiation exposure compared to PET\/CT, it might be the preferable option if readily available.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00066-025-02446-4","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T06:45:18Z","timestamp":1755153918000},"page":"1143-1150","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of pretreatment PET\/MRI on radiooncologic target delineation in Hodgkin\u2019s lymphoma: a\u00a0case series"],"prefix":"10.1007","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2145-0524","authenticated-orcid":false,"given":"Kai","family":"Kr\u00f6ger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Lohmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Oertel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Borchmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Kerkhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Lenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Stegger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Theodor","family":"Eich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"2446_CR1","doi-asserted-by":"publisher","first-page":"3048","DOI":"10.1200\/JCO.2013.53.5229","volume":"32","author":"SF Barrington","year":"2014","unstructured":"Barrington\u00a0SF, Mikhaeel\u00a0NG, Kostakoglu\u00a0L, Meignan\u00a0M, Hutchings\u00a0M, M\u00fceller\u00a0SP, Schwartz\u00a0LH, Zucca\u00a0E, Fisher\u00a0RI, Trotman\u00a0J, Hoekstra\u00a0OS, Hicks\u00a0RJ, O\u2019Doherty\u00a0MJ, Hustinx\u00a0R, Biggi\u00a0A, Cheson\u00a0BD (2014) Role of imaging in the staging and response assessment of lymphoma: consensus of the international conference on malignant lymphomas imaging working group. JCO 32:3048\u20133058. https:\/\/doi.org\/10.1200\/JCO.2013.53.5229","journal-title":"JCO"},{"key":"2446_CR2","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3109\/10428194.2014.919635","volume":"56","author":"E Bednaruk-M\u0142y\u0144ski","year":"2015","unstructured":"Bednaruk-M\u0142y\u0144ski\u00a0E, Pie\u0144kowska\u00a0J, Sk\u00f3rzak\u00a0A, Ma\u0142kowski\u00a0B, Kulikowski\u00a0W, Subocz\u00a0E, Dzietczenia\u00a0J, Zalewska\u00a0M, Le\u015bniewski-Kmak\u00a0K, Zaucha\u00a0R, Wr\u00f3bel\u00a0T, Zaucha\u00a0JM (2015) Comparison of positron emission tomography\/computed tomography with classical contrast-enhanced computed tomography in the initial staging of hodgkin lymphoma. Leuk Lymphoma 56:377\u2013382. https:\/\/doi.org\/10.3109\/10428194.2014.919635","journal-title":"Leuk Lymphoma"},{"key":"2446_CR3","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.radonc.2017.05.014","volume":"124","author":"D Bird","year":"2017","unstructured":"Bird\u00a0D, Patel\u00a0C, Scarsbrook\u00a0AF, Cosgrove\u00a0V, Thomas\u00a0E, Gilson\u00a0D, Prestwich\u00a0RJD (2017) Evaluation of clinical target volume expansion required for involved site neck radiotherapy for lymphoma to account for the absence of a\u00a0pre-chemotherapy PET-CT in the radiotherapy treatment position. Radiother Oncol 124:161\u2013167. https:\/\/doi.org\/10.1016\/j.radonc.2017.05.014","journal-title":"Radiother Oncol"},{"key":"2446_CR4","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S0140-6736(24)01315-1","volume":"404","author":"P Borchmann","year":"2024","unstructured":"Borchmann\u00a0P, Ferdinandus\u00a0J, Schneider\u00a0G, Moccia\u00a0A, Greil\u00a0R, Hertzberg\u00a0M, Schaub\u00a0V, H\u00fcttmann\u00a0A, Keil\u00a0F, Dierlamm\u00a0J, H\u00e4nel\u00a0M, Novak\u00a0U, Meissner\u00a0J, Zimmermann\u00a0A, Mathas\u00a0S, Zijlstra\u00a0JM, Foss\u00e5\u00a0A, Viardot\u00a0A, Hertenstein\u00a0B, Martin\u00a0S, Giri\u00a0P, Scholl\u00a0S, Topp\u00a0MS, Jung\u00a0W, Vucinic\u00a0V, Beck\u00a0H\u2011J, Kerkhoff\u00a0A, Unger\u00a0B, Rank\u00a0A, Schroers\u00a0R, Zum B\u00fcschenfelde\u00a0CM, de Wit\u00a0M, Trautmann-Grill\u00a0K, Kamper\u00a0P, Molin\u00a0D, Kreissl\u00a0S, Kaul\u00a0H, von Tresckow\u00a0B, Borchmann\u00a0S, Behringer\u00a0K, Fuchs\u00a0M, Rosenwald\u00a0A, Klapper\u00a0W, Eich\u00a0H\u2011T, Baues\u00a0C, Zomas\u00a0A, Hallek\u00a0M, Dietlein\u00a0M, Kobe\u00a0C, Diehl\u00a0V, German Hodgkin Study Group, Swiss Group for Clinical Cancer Research, Arbeitsgemeinschaft Medikament\u00f6se Tumortherapie, Nordic Lymphoma Group, Australasian Leukaemia and Lymphoma Group (2024) Assessing the efficacy and tolerability of PET-guided brECADD versus eBEACOPP in advanced-stage, classical hodgkin lymphoma (HD21): a\u00a0randomised, multicentre, parallel, open-label, phase\u00a03\u00a0trial. Lancet 404:341\u2013352. https:\/\/doi.org\/10.1016\/S0140-6736(24)01315-1","journal-title":"Lancet"},{"key":"2446_CR5","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S1470-2045(20)30601-X","volume":"22","author":"P Borchmann","year":"2021","unstructured":"Borchmann\u00a0P, Pl\u00fctschow\u00a0A, Kobe\u00a0C, Greil\u00a0R, Meissner\u00a0J, Topp\u00a0MS, Ostermann\u00a0H, Dierlamm\u00a0J, Mohm\u00a0J, Thiemer\u00a0J, S\u00f6kler\u00a0M, Kerkhoff\u00a0A, Ahlborn\u00a0M, Halbsguth\u00a0TV, Martin\u00a0S, Keller\u00a0U, Balabanov\u00a0S, Pabst\u00a0T, Vogelhuber\u00a0M, H\u00fcttmann\u00a0A, Wilhelm\u00a0M, Zijlstra\u00a0JM, Moccia\u00a0A, Kuhnert\u00a0G, Br\u00f6ckelmann\u00a0PJ, von Tresckow\u00a0B, Fuchs\u00a0M, Klimm\u00a0B, Rosenwald\u00a0A, Eich\u00a0H, Baues\u00a0C, Marnitz\u00a0S, Hallek\u00a0M, Diehl\u00a0V, Dietlein\u00a0M, Engert\u00a0A (2021) PET-guided omission of radiotherapy in early-stage unfavourable hodgkin lymphoma (GHSG HD\u00a017): a\u00a0multicentre, open-label, randomised, phase\u00a03\u00a0trial. Lancet Oncol 22:223\u2013234. https:\/\/doi.org\/10.1016\/S1470-2045(20)30601-X","journal-title":"Lancet Oncol"},{"key":"2446_CR6","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.m2022.0395","author":"D Bos","year":"2023","unstructured":"Bos\u00a0D, Guberina\u00a0N, Zensen\u00a0S, Opitz\u00a0M, Forsting\u00a0M, Wetter\u00a0A (2023) Radiation exposure in computed tomography. Dtsch \u00c4rztebl Int. https:\/\/doi.org\/10.3238\/arztebl.m2022.0395","journal-title":"Dtsch \u00c4rztebl Int"},{"key":"2446_CR7","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/S1470-2045(18)30784-8","volume":"20","author":"R-O Casasnovas","year":"2019","unstructured":"Casasnovas\u00a0R\u2011O, Bouabdallah\u00a0R, Brice\u00a0P, Lazarovici\u00a0J, Ghesquieres\u00a0H, Stamatoullas\u00a0A, Dupuis\u00a0J, Gac\u00a0A\u2011C, Gastinne\u00a0T, Joly\u00a0B, Bouabdallah\u00a0K, Nicolas-Virelizier\u00a0E, Feugier\u00a0P, Morschhauser\u00a0F, Delarue\u00a0R, Farhat\u00a0H, Quittet\u00a0P, Berriolo-Riedinger\u00a0A, Tempescul\u00a0A, Edeline\u00a0V, Maisonneuve\u00a0H, Fornecker\u00a0L\u2011M, Lamy\u00a0T, Delmer\u00a0A, Dartigues\u00a0P, Martin\u00a0L, Andr\u00e9\u00a0M, Mounier\u00a0N, Traverse-Glehen\u00a0A, Meignan\u00a0M (2019) PET-adapted treatment for newly diagnosed advanced hodgkin lymphoma (AHL2011): a\u00a0randomised, multicentre, non-inferiority, phase\u00a03\u00a0study. Lancet Oncol 20:202\u2013215. https:\/\/doi.org\/10.1016\/S1470-2045(18)30784-8","journal-title":"Lancet Oncol"},{"key":"2446_CR8","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.1200\/JCO.2013.54.8800","volume":"32","author":"BD Cheson","year":"2014","unstructured":"Cheson\u00a0BD, Fisher\u00a0RI, Barrington\u00a0SF, Cavalli\u00a0F, Schwartz\u00a0LH, Zucca\u00a0E, Lister\u00a0TA (2014) Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the lugano classification. JCO 32:3059\u20133067. https:\/\/doi.org\/10.1200\/JCO.2013.54.8800","journal-title":"JCO"},{"key":"2446_CR9","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.3390\/cancers16061206","volume":"16","author":"DOM Lemus","year":"2024","unstructured":"Lemus\u00a0DOM, Cao\u00a0M, Cai\u00a0B, Cummings\u00a0M, Zheng\u00a0D (2024) Adaptive radiotherapy: next-generation radiotherapy. Cancers 16:1206. https:\/\/doi.org\/10.3390\/cancers16061206","journal-title":"Cancers"},{"key":"2446_CR10","doi-asserted-by":"publisher","first-page":"4199","DOI":"10.1200\/JCO.2010.29.8018","volume":"28","author":"HT Eich","year":"2010","unstructured":"Eich\u00a0HT, Diehl\u00a0V, G\u00f6rgen\u00a0H, Pabst\u00a0T, Markova\u00a0J, Debus\u00a0J, Ho\u00a0A, D\u00f6rken\u00a0B, Rank\u00a0A, Grosu\u00a0A\u2011L, Wiegel\u00a0T, Karstens\u00a0JH, Greil\u00a0R, Willich\u00a0N, Schmidberger\u00a0H, D\u00f6hner\u00a0H, Borchmann\u00a0P, M\u00fcller-Hermelink\u00a0H\u2011K, M\u00fcller\u00a0R\u2011P, Engert\u00a0A (2010) Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable hodgkin\u2019s lymphoma: final analysis of the German hodgkin study group HD11 trial. JCO 28:4199\u20134206. https:\/\/doi.org\/10.1200\/JCO.2010.29.8018","journal-title":"JCO"},{"key":"2446_CR11","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.6004\/jnccn.2011.0088","volume":"9","author":"HT Eich","year":"2011","unstructured":"Eich\u00a0HT, Kriz\u00a0J, M\u00fcller\u00a0R\u2011P (2011) Evolution of radiation therapy within the German hodgkin study group trials. J\u00a0Natl Compr Canc Netw 9:1073\u20131080. https:\/\/doi.org\/10.6004\/jnccn.2011.0088","journal-title":"J Natl Compr Canc Netw"},{"key":"2446_CR12","doi-asserted-by":"publisher","first-page":"96","DOI":"10.2967\/jnumed.122.264112","volume":"64","author":"TW Georgi","year":"2023","unstructured":"Georgi\u00a0TW, Stoevesandt\u00a0D, Kurch\u00a0L, Bartelt\u00a0JM, Hasenclever\u00a0D, Dittmann\u00a0H, Ferda\u00a0J, Francis\u00a0P, Franzius\u00a0C, Furth\u00a0C, Gr\u00e4fe\u00a0D, Gussew\u00a0A, H\u00fcllner\u00a0M, Menezes\u00a0LJ, Mustafa\u00a0M, Stegger\u00a0L, Umutlu\u00a0L, Z\u00f6phel\u00a0K, Zucchetta\u00a0P, K\u00f6rholz\u00a0D, Sabri\u00a0O, Mauz-K\u00f6rholz\u00a0C, Kluge\u00a0R (2023) Optimized whole-body PET MRI sequence workflow in pediatric hodgkin lymphoma patients. J\u00a0Nucl Med 64:96\u2013101. https:\/\/doi.org\/10.2967\/jnumed.122.264112","journal-title":"J Nucl Med"},{"key":"2446_CR13","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/j.ijrobp.2014.04.026","volume":"89","author":"T Girinsky","year":"2014","unstructured":"Girinsky\u00a0T, Aup\u00e9rin\u00a0A, Ribrag\u00a0V, Elleuch\u00a0M, Ferm\u00e9\u00a0C, Bonniaud\u00a0G, Ruelle\u00a0C, Alberini\u00a0J\u2011L, Celebic\u00a0A, Edeline\u00a0V (2014) Role of FDG-PET in the implementation of involved-node radiation therapy for hodgkin lymphoma patients. Int J Radiat Oncol 89:1047\u20131052. https:\/\/doi.org\/10.1016\/j.ijrobp.2014.04.026","journal-title":"Int J Radiat Oncol"},{"key":"2446_CR14","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1007\/s00247-024-06009-0","volume":"55","author":"C Granata","year":"2025","unstructured":"Granata\u00a0C, Sofia\u00a0C, Francavilla\u00a0M, Kardos\u00a0M, Kasznia-Brown\u00a0J, Nievelstein\u00a0RA, Olteanu\u00a0BS, Owens\u00a0C, Salerno\u00a0S, Sorantin\u00a0E, Apine\u00a0I (2025) Let\u2019s talk about radiation dose and radiation protection in children. Pediatr Radiol 55:386\u2013396. https:\/\/doi.org\/10.1007\/s00247-024-06009-0","journal-title":"Pediatr Radiol"},{"key":"2446_CR15","doi-asserted-by":"publisher","first-page":"842","DOI":"10.2214\/AJR.14.13181","volume":"204","author":"L Heacock","year":"2015","unstructured":"Heacock\u00a0L, Weissbrot\u00a0J, Raad\u00a0R, Campbell\u00a0N, Friedman\u00a0KP, Ponzo\u00a0F, Chandarana\u00a0H (2015) PET\/MRI for the evaluation of patients with lymphoma: initial observations. Am J Roentgenol 204:842\u2013848. https:\/\/doi.org\/10.2214\/AJR.14.13181","journal-title":"Am J Roentgenol"},{"key":"2446_CR16","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1186\/s12885-022-09758-z","volume":"22","author":"L van Heek","year":"2022","unstructured":"van Heek\u00a0L, Stuka\u00a0C, Kaul\u00a0H, M\u00fcller\u00a0H, Mettler\u00a0J, Hitz\u00a0F, Baues\u00a0C, Fuchs\u00a0M, Borchmann\u00a0P, Engert\u00a0A, Dietlein\u00a0M, Voltin\u00a0C\u2011A, Kobe\u00a0C (2022) Predictive value of baseline metabolic tumor volume in early-stage favorable hodgkin lymphoma\u2014data from the prospective, multicenter phase\u00a0III HD16 trial. BMC Cancer 22:672. https:\/\/doi.org\/10.1186\/s12885-022-09758-z","journal-title":"BMC Cancer"},{"key":"2446_CR17","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1016\/j.ejrad.2013.01.008","volume":"82","author":"P Heusch","year":"2013","unstructured":"Heusch\u00a0P, Buchbender\u00a0C, Beiderwellen\u00a0K, Nensa\u00a0F, Hartung-Knemeyer\u00a0V, Lauenstein\u00a0TC, Bockisch\u00a0A, Forsting\u00a0M, Antoch\u00a0G, Heusner\u00a0TA (2013) Standardized uptake values for [18F] FDG in normal organ tissues: comparison of whole-body PET\/CT and PET\/MRI. Eur J Radiol 82:870\u2013876. https:\/\/doi.org\/10.1016\/j.ejrad.2013.01.008","journal-title":"Eur J Radiol"},{"key":"2446_CR18","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.1600-0609.2006.00802.x","volume":"78","author":"M Hutchings","year":"2007","unstructured":"Hutchings\u00a0M, Loft\u00a0A, Hansen\u00a0M, Berthelsen\u00a0AK, Specht\u00a0L (2007) Clinical impact of FDG-PET\/CT in the planning of radiotherapy for early-stage hodgkin lymphoma. Eur J Haematol 78:206\u2013212. https:\/\/doi.org\/10.1111\/j.1600-0609.2006.00802.x","journal-title":"Eur J Haematol"},{"key":"2446_CR19","volume-title":"S3-Leitlinie hodgkin lymphom","author":"T Jakob","year":"2022","unstructured":"Jakob\u00a0T, Onkologie\u00a0L (2022) S3-Leitlinie hodgkin lymphom"},{"key":"2446_CR20","doi-asserted-by":"publisher","first-page":"207","DOI":"10.2967\/jnumed.118.210047","volume":"60","author":"J Mettler","year":"2018","unstructured":"Mettler\u00a0J, M\u00fcller\u00a0H, Voltin\u00a0C\u2011A, Baues\u00a0C, Klaeser\u00a0B, Moccia\u00a0A, Borchmann\u00a0P, Engert\u00a0A, Kuhnert\u00a0G, Drzezga\u00a0AE, Dietlein\u00a0M, Kobe\u00a0C (2018) Metabolic tumour volume for response prediction in advanced-stage hodgkin lymphoma. J\u00a0Nucl Med 60:207\u2013211. https:\/\/doi.org\/10.2967\/jnumed.118.210047","journal-title":"J Nucl Med"},{"key":"2446_CR21","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.ijrobp.2010.02.024","volume":"80","author":"H Metwally","year":"2011","unstructured":"Metwally\u00a0H, Courbon\u00a0F, David\u00a0I, Filleron\u00a0T, Blouet\u00a0A, Rives\u00a0M, Izar\u00a0F, Zerdoud\u00a0S, Plat\u00a0G, Vial\u00a0J, Robert\u00a0A, Laprie\u00a0A (2011) Coregistration of Prechemotherapy PET-CT for planning pediatric hodgkin\u2019s disease radiotherapy significantly diminishes Interobserver variability of clinical target volume definition. Int J Radiat Oncol Biol Phys 80:793\u2013799. https:\/\/doi.org\/10.1016\/j.ijrobp.2010.02.024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2446_CR22","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1053\/j.semnuclmed.2022.09.001","volume":"53","author":"NB Pepper","year":"2023","unstructured":"Pepper\u00a0NB, Oertel\u00a0M, Rehn\u00a0S, Kobe\u00a0C, Eich\u00a0HT (2023) Modern PET-guided radiotherapy planning and treatment for malignant lymphoma. Semin Nucl Med 53:389\u2013399. https:\/\/doi.org\/10.1053\/j.semnuclmed.2022.09.001","journal-title":"Semin Nucl Med"},{"key":"2446_CR23","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1007\/s00277-021-04537-5","volume":"100","author":"M Picardi","year":"2021","unstructured":"Picardi\u00a0M, Cavaliere\u00a0C, Pepa\u00a0DR, Nicolai\u00a0E, Soricelli\u00a0A, Giordano\u00a0C, Pugliese\u00a0N, Rascato\u00a0MG, Cappuccio\u00a0I, Campagna\u00a0G, Cerchione\u00a0C, Vigliar\u00a0E, Troncone\u00a0G, Mascolo\u00a0M, Franzese\u00a0M, Castaldo\u00a0R, Salvatore\u00a0M, Pane\u00a0F (2021) PET\/MRI for staging patients with hodgkin lymphoma: equivalent results with PET\/CT in a\u00a0prospective trial. Ann Hematol 100:1525\u20131535. https:\/\/doi.org\/10.1007\/s00277-021-04537-5","journal-title":"Ann Hematol"},{"key":"2446_CR24","doi-asserted-by":"publisher","first-page":"623","DOI":"10.2214\/AJR.15.15083","volume":"206","author":"AC Sher","year":"2016","unstructured":"Sher\u00a0AC, Seghers\u00a0V, Paldino\u00a0MJ, Dodge\u00a0C, Krishnamurthy\u00a0R, Krishnamurthy\u00a0R, Rohren\u00a0EM (2016) Assessment of sequential PET\/MRI in comparison with PET\/CT of pediatric lymphoma: a\u00a0prospective study. Am J Roentgenol 206:623\u2013631. https:\/\/doi.org\/10.2214\/AJR.15.15083","journal-title":"Am J Roentgenol"},{"key":"2446_CR25","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1053\/j.semnuclmed.2017.09.006","volume":"48","author":"L Specht","year":"2018","unstructured":"Specht\u00a0L, Berthelsen\u00a0AK (2018) PET\/CT in radiation therapy planning. Semin Nucl Med 48:67\u201375. https:\/\/doi.org\/10.1053\/j.semnuclmed.2017.09.006","journal-title":"Semin Nucl Med"},{"key":"2446_CR26","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.ijrobp.2013.05.005","volume":"89","author":"L Specht","year":"2014","unstructured":"Specht\u00a0L, Yahalom\u00a0J, Illidge\u00a0T, Berthelsen\u00a0AK, Constine\u00a0LS, Eich\u00a0HT, Girinsky\u00a0T, Hoppe\u00a0RT, Mauch\u00a0P, Mikhaeel\u00a0NG, Ng\u00a0A (2014) Modern radiation therapy for hodgkin lymphoma: field and dose guidelines from the international lymphoma radiation oncology group (ILROG). Int J Radiat Oncol 89:854\u2013862. https:\/\/doi.org\/10.1016\/j.ijrobp.2013.05.005","journal-title":"Int J Radiat Oncol"},{"key":"2446_CR27","doi-asserted-by":"publisher","first-page":"420","DOI":"10.2967\/jnumed.115.158808","volume":"57","author":"C Spick","year":"2016","unstructured":"Spick\u00a0C, Herrmann\u00a0K, Czernin\u00a0J (2016) 18F-FDG PET\/CT and PET\/MRI perform equally well in cancer: evidence from studies on more than 2,300 patients. J\u00a0Nucl Med 57:420\u2013430. https:\/\/doi.org\/10.2967\/jnumed.115.158808","journal-title":"J Nucl Med"},{"key":"2446_CR28","volume-title":"German commission on radiological protection","author":"Strahlenschutzkommission","year":"2022","unstructured":"Strahlenschutzkommission (2022) German commission on radiological protection. Bildgebende Diagnostik bei Kindern"},{"key":"2446_CR29","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12880-015-0068-x","volume":"15","author":"AA Taha","year":"2015","unstructured":"Taha\u00a0AA, Hanbury\u00a0A (2015) Metrics for evaluating 3D medical image segmentation: analysis, selection, and tool. BMC Med Imaging 15:29. https:\/\/doi.org\/10.1186\/s12880-015-0068-x","journal-title":"BMC Med Imaging"},{"key":"2446_CR30","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.ijrobp.2014.02.006","volume":"89","author":"SA Terezakis","year":"2014","unstructured":"Terezakis\u00a0SA, Sch\u00f6der\u00a0H, Kowalski\u00a0A, McCann\u00a0P, Lim\u00a0R, Turlakov\u00a0A, Gonen\u00a0M, Barker\u00a0C, Goenka\u00a0A, Lovie\u00a0S, Yahalom\u00a0J (2014) A prospective study of 18FDG-PET with CT co-registration for radiation treatment planning of lymphomas and other hematologic malignancies. Int J Radiat Oncol Biol Phys 89:376\u2013383. https:\/\/doi.org\/10.1016\/j.ijrobp.2014.02.006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2446_CR31","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.3390\/cancers11081071","volume":"11","author":"TP Vassilakopoulos","year":"2019","unstructured":"Vassilakopoulos\u00a0TP, Chatzidimitriou\u00a0C, Asimakopoulos\u00a0JV, Arapaki\u00a0M, Tzoras\u00a0E, Angelopoulou\u00a0MK, Konstantopoulos\u00a0K (2019) Immunotherapy in hodgkin lymphoma: present status and future strategies. Cancers 11:1071. https:\/\/doi.org\/10.3390\/cancers11081071","journal-title":"Cancers"},{"key":"2446_CR32","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1158\/1078-0432.CCR-20-3303","volume":"27","author":"C-A Voltin","year":"2021","unstructured":"Voltin\u00a0C\u2011A, Mettler\u00a0J, Van Heek\u00a0L, Goergen\u00a0H, M\u00fcller\u00a0H, Baues\u00a0C, Keller\u00a0U, Meissner\u00a0J, Trautmann-Grill\u00a0K, Kerkhoff\u00a0A, Fuchs\u00a0M, Sasse\u00a0S, Von Tresckow\u00a0B, Dietlein\u00a0M, Borchmann\u00a0P, Engert\u00a0A, Kobe\u00a0C, Br\u00f6ckelmann\u00a0PJ (2021) Early response to first-line anti-PD\u20111 treatment in hodgkin lymphoma: a\u00a0PET-based analysis from the prospective, randomized phase\u00a0II NIVAHL trial. Clin Cancer Res 27:402\u2013407. https:\/\/doi.org\/10.1158\/1078-0432.CCR-20-3303","journal-title":"Clin Cancer Res"}],"container-title":["Strahlentherapie und Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-025-02446-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00066-025-02446-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00066-025-02446-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:41:16Z","timestamp":1761154876000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00066-025-02446-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":32,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["2446"],"URL":"https:\/\/doi.org\/10.1007\/s00066-025-02446-4","relation":{},"ISSN":["0179-7158","1439-099X"],"issn-type":[{"type":"print","value":"0179-7158"},{"type":"electronic","value":"1439-099X"}],"subject":[],"published":{"date-parts":[[2025,8,14]]},"assertion":[{"value":"13 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"K.\u00a0Kr\u00f6ger, S.\u00a0Lohmann, M.\u00a0Oertel, P.\u00a0Borchmann, A.\u00a0Kerkhoff, G.\u00a0Lenz, L.\u00a0Stegger, and H.T.\u00a0Eich declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethics approval\n                      : The retrospective analysis was approved by the local ethics committee (Ethics Committee of the Medical Association of Westphalia-Lippe and the University of M\u00fcnster, 2024-583-f-S).\n                      Informed consent statement\n                      : Patient consent was waived due to the retrospective monocentric nature of the analysis.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}