{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:15:30Z","timestamp":1740147330107,"version":"3.37.3"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T00:00:00Z","timestamp":1630713600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T00:00:00Z","timestamp":1630713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Trauma Emerg Surg"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s00068-021-01769-y","type":"journal-article","created":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T07:02:41Z","timestamp":1630738961000},"page":"2013-2022","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Risk factors of surgical mortality in patients with Clostridium difficile colitis. A novel scoring system"],"prefix":"10.1007","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8347-0726","authenticated-orcid":false,"given":"Nasim","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen-Hong","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robyn K.","family":"Guinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan","family":"Purewal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,9,4]]},"reference":[{"key":"1769_CR1","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3201\/eid1205.051064","volume":"12","author":"LC McDonald","year":"2006","unstructured":"McDonald LC, Owings M, Jernigan JB. Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996 to 2003. Emerg Infect Dis. 2006;12:409\u201315. Accessed 9 sept 2020","journal-title":"Emerg Infect Dis"},{"key":"1769_CR2","unstructured":"https:\/\/www.cdc.gov\/drugresistance\/biggest-threats.html#cdiff"},{"issue":"5","key":"1769_CR3","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1056\/NEJMoa0910812","volume":"364","author":"TJ Louie","year":"2011","unstructured":"Louie TJ, Miller MA, Mullane KM, OPT-80-003 Clinical Study Group, et al. Fidaxomicin versus vancomycin for Clostridium difficile infection. N Engl J Med. 2011;364(5):422\u201331. https:\/\/doi.org\/10.1056\/NEJMoa0910812 (Medline: 21288078).","journal-title":"N Engl J Med"},{"key":"1769_CR4","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S1473-3099(05)70215-2","volume":"5","author":"S Aslam","year":"2005","unstructured":"Aslam S, Hamill RJ, Musher DM. Treatment of Clostridium difficile-associated disease: old therapies and new strategies. Lancet Infect Dis. 2005;5:549\u201357.","journal-title":"Lancet Infect Dis"},{"issue":"Suppl 2","key":"1769_CR5","doi-asserted-by":"publisher","first-page":"S154","DOI":"10.1093\/cid\/cis462","volume":"55","author":"OA Cornely","year":"2012","unstructured":"Cornely OA, Miller MA, Louie TJ, et al. Treatment of first recurrence of Clostridium difficile infection: fidaxomicin versus vancomycin. Clin Infect Dis. 2012;55(Suppl 2):S154\u201361.","journal-title":"Clin Infect Dis"},{"key":"1769_CR6","doi-asserted-by":"publisher","first-page":"1932","DOI":"10.1056\/NEJMra0707500","volume":"359","author":"CP Kelly","year":"2008","unstructured":"Kelly CP, LaMont JT. Clostridium difficile\u2014more difficult than ever. N Engl J Med. 2008;359:1932\u201340.","journal-title":"N Engl J Med"},{"key":"1769_CR7","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1056\/NEJMoa0907635","volume":"362","author":"I Lowy","year":"2010","unstructured":"Lowy I, Molrine DC, Leav BA, et al. Treatment with monoclonal antibodies against Clostridium difficile toxins. N Engl J Med. 2010;362:197\u2013205.","journal-title":"N Engl J Med"},{"key":"1769_CR8","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1001\/archsurg.2009.51","volume":"144","author":"EA Sailhamer","year":"2009","unstructured":"Sailhamer EA, Carson K, Chang Y, Zacharias N, Spaniolas K, Tabbara M, Alam HB, DeMoya MA, Velmahos GC. Fulminant Clostridium difficile colitis; patterns of care and predictor of mortality. Arch Surg. 2009;144:433\u20139 (discussion 439-40).","journal-title":"Arch Surg"},{"issue":"10","key":"1769_CR9","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1007\/s10350-004-0672-2","volume":"47","author":"WE Longo","year":"2004","unstructured":"Longo WE, Mazuski JE, Virgo KS, Lee PB, Ahadursingh AN, Johnson FE. Outcome after colectomy for Clostridium difficile colitis. Dis Colon Rectum. 2004;47(10):1620\u20136.","journal-title":"Dis Colon Rectum"},{"issue":"2","key":"1769_CR10","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1097\/01.sla.0000236628.79550.e5","volume":"245","author":"F Lamontagne","year":"2007","unstructured":"Lamontagne F, Labbe AC, Haeck O, et al. Impact of emergency colectomy of survival of patients with fulminant Clostridium difficile colitis during an epidemic caused by a hypervirulent strain. Ann Surg. 2007;245(2):267\u201372.","journal-title":"Ann Surg"},{"issue":"3","key":"1769_CR11","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1097\/00000658-200203000-00008","volume":"235","author":"RM Dallal","year":"2002","unstructured":"Dallal RM, Harbrecht BG, Boujoukas AJ, et al. Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications. Ann Surg. 2002;235(3):363\u201372.","journal-title":"Ann Surg"},{"issue":"3","key":"1769_CR12","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.amjsurg.2008.11.001","volume":"197","author":"CW Seder","year":"2009","unstructured":"Seder CW, Villalba MR Jr, Robbins J, Ivascu FA, Carpenter CF, Dietrich M, Villalba MR Sr. Early colectomy may be associated with improved survival in fulminant Clostridium difficile colitis: an 8-year experience. Am J Surg. 2009;197(3):302\u20137.","journal-title":"Am J Surg"},{"issue":"6","key":"1769_CR13","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1111\/apt.13546","volume":"43","author":"Z Kassam","year":"2016","unstructured":"Kassam Z, Cribb Fabersunne C, Smith MB, Alm EJ, Kaplan GG, Nguyen GC, Ananthakrishnan AN. Clostridium difficile associated risk of death score (CARDS): a novel severity score to predict mortality among hospitalized patients with Clostridium difficile infection. Aliment Pharmacol Ther. 2016;43(6):725\u201333.","journal-title":"Aliment Pharmacol Ther"},{"issue":"12","key":"1769_CR14","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1097\/DCR.0000000000000920","volume":"60","author":"AS Kulaylat","year":"2017","unstructured":"Kulaylat AS, Kassam Z, Hollenbeak CS, Stewart DB Sr. A surgical Clostridium-associated risk of death score predicts mortality after colectomy for Clostridium difficile. Dis Colon Rectum. 2017;60(12):1285\u201390. https:\/\/doi.org\/10.1097\/DCR.0000000000000920.","journal-title":"Dis Colon Rectum"},{"issue":"1","key":"1769_CR15","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1097\/SLA.0b013e31828a8eba","volume":"259","author":"DY Lee","year":"2014","unstructured":"Lee DY, Chung EL, Guend H, Whelan RL, Wedderburn RV, Rose KM. Predictors of mortality after emergency colectomy for Clostridium difficile colitis: an analysis of ACS-NSQIP. Ann Surg. 2014;259(1):148\u201356. https:\/\/doi.org\/10.1097\/SLA.0b013e31828a8eba.","journal-title":"Ann Surg"},{"issue":"4","key":"1769_CR16","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1097\/TA.0000000000002412","volume":"87","author":"M Abou Khalil","year":"2019","unstructured":"Abou Khalil M, Bhatnagar SR, Feldman L, et al. Development and validation of a clinical risk calculator for mortality after colectomy for fulminant Clostridium difficile colitis. J Trauma Acute Care Surg. 2019;87(4):856\u201364. https:\/\/doi.org\/10.1097\/TA.0000000000002412.","journal-title":"J Trauma Acute Care Surg"},{"issue":"5","key":"1769_CR17","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.jamcollsurg.2013.05.028","volume":"217","author":"WJ Halabi","year":"2013","unstructured":"Halabi WJ, Nguyen VQ, Carmichael JC, Pigazzi A, Stamos MJ, Mills S. Clostridium difficile colitis in the United States: a decade of trends, outcomes, risk factors for colectomy, and mortality after colectomy. J Am Coll Surg. 2013;217(5):802\u201312. https:\/\/doi.org\/10.1016\/j.jamcollsurg.2013.05.028.","journal-title":"J Am Coll Surg"},{"issue":"3","key":"1769_CR18","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1007\/DCR.0b013e31819a69aa","volume":"52","author":"J Pepin","year":"2009","unstructured":"Pepin J, Vo TT, Boutros M, Marcotte E, Dial S, Dub\u00e9 S, Vasilevsky CA, McFadden N, Patino C, Labb\u00e9 AC. Risk factors for mortality following emergency colectomy for fulminant Clostridium difficile infection. Dis Colon Rectum. 2009;52(3):400\u20135.","journal-title":"Dis Colon Rectum"},{"key":"1769_CR19","unstructured":"https:\/\/www.facs.org\/quality-programs\/acs-nsqip. Accessed 3 Sept 2020."},{"issue":"7","key":"1769_CR20","doi-asserted-by":"publisher","first-page":"345","DOI":"10.14423\/SMJ.0000000000001118","volume":"113","author":"N Ahmed","year":"2020","unstructured":"Ahmed N, Kuo YH. Early colectomy saves lives in toxic megacolon due to clostridium difficile infection. South Med J. 2020;113(7):345\u20139. https:\/\/doi.org\/10.14423\/SMJ.0000000000001118.","journal-title":"South Med J"},{"issue":"10","key":"1769_CR21","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","volume":"13","author":"WA Knaus","year":"1985","unstructured":"Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13(10):818\u201329.","journal-title":"Crit Care Med"},{"key":"1769_CR22","unstructured":"R Core Team (2018) R: a language and environment for statistical computing, R Foundation for Statistical Computing, Vienna. https:\/\/www.R-project.org\/."},{"key":"1769_CR23","volume-title":"Stata statistical software: release 15","author":"StataCorp","year":"2017","unstructured":"StataCorp. Stata statistical software: release 15. College Station, TX: StataCorp LLC; 2017."},{"key":"1769_CR24","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/0895-4356(95)00068-2","volume":"49","author":"F Harrell","year":"1996","unstructured":"Harrell F. Regression coefficients and scoring rules. J Clin Epidemiol. 1996;49:819.","journal-title":"J Clin Epidemiol"},{"key":"1769_CR25","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1016\/S0895-4356(02)00453-5","volume":"55","author":"KGM Moons","year":"2002","unstructured":"Moons KGM, Harrell FE, Steyerberg EW. Should scoring rules be based on odds ratios or regression coefficients? J Clin Epidemiol. 2002;55:1054\u20135.","journal-title":"J Clin Epidemiol"},{"issue":"2","key":"1769_CR26","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1097\/TA.0000000000002745","volume":"89","author":"A Barazanchi","year":"2020","unstructured":"Barazanchi A, Bhat S, Palmer-Neels K, Macfater WS, Xia W, Zeng I, Taneja A, MacCormick AD, Hill AG. Evaluating and improving current risk prediction tools in emergency laparotomy. J Trauma Acute Care Surg. 2020;89(2):382\u20137. https:\/\/doi.org\/10.1097\/TA.0000000000002745.","journal-title":"J Trauma Acute Care Surg"}],"container-title":["European Journal of Trauma and Emergency Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00068-021-01769-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00068-021-01769-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00068-021-01769-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T18:19:55Z","timestamp":1655144395000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00068-021-01769-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,4]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["1769"],"URL":"https:\/\/doi.org\/10.1007\/s00068-021-01769-y","relation":{},"ISSN":["1863-9933","1863-9941"],"issn-type":[{"type":"print","value":"1863-9933"},{"type":"electronic","value":"1863-9941"}],"subject":[],"published":{"date-parts":[[2021,9,4]]},"assertion":[{"value":"25 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}