{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T17:17:06Z","timestamp":1785345426296,"version":"3.55.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Bonn"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Trauma Emerg Surg"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>The best time for cranioplasty (CP) after decompressive craniectomy (DC) is controversial, and there are no authoritative guidelines yet. Both complications as well as outcome may depend on the timing of CP. The aim of this single-center study was to evaluate the impact of late CP on procedural safety as well as on patient outcome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>All patients receiving CP at a tertiary university medical center between 01\/2015 and 12\/2022 were included retrospectively. Patients\u2019 conditions were assessed according to the modified Rankin Scale (mRS) prior to CP and 6\u00a0months after. Baseline characteristics, indication for DC, time from DC to CP, and postoperative complications according to the Landriel Iba\u00f1ez Classification were analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>CP was performed in 271 patients who previously underwent DC due to traumatic brain injury (25.5%), ischemic stroke (29.5%), aneurysmal subarachnoid hemorrhage (26.9%), or intracerebral hemorrhage (18.1%). The median interval between DC and CP was 143\u00a0days (interquartile range 112\u2013184\u00a0days). Receiver operating characteristic analysis revealed a cut-off of 149\u00a0days, where CP performed within 149\u00a0days after DC led to an improvement on mRS after CP (<jats:italic>p<\/jats:italic>\u2009=\u20090.001). In multivariate analysis, additional rehabilitation after and better mRS before CP were independently associated with improvement of outcome. The rate of complications was similar between early and late CP (24.8% and 25.4%, respectively, <jats:italic>p<\/jats:italic>\u2009=\u20090.562).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Late cranioplasty is a safe procedure. The outcome was improved when additional rehabilitation was performed after cranioplasty and was not associated with the timing of cranioplasty.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00068-024-02479-x","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T07:02:11Z","timestamp":1709276531000},"page":"1503-1511","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Functional outcome after late cranioplasty after decompressive craniectomy: a single-center retrospective study"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2607-2024","authenticated-orcid":false,"given":"Tim","family":"Lampmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harun","family":"Asoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Weller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Laura","family":"Potthoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Banat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank Alexander","family":"Schildberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartmut","family":"Vatter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motaz","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeri","family":"Borger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,1]]},"reference":[{"key":"2479_CR1","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.1007\/s10143-020-01383-3","volume":"44","author":"S Brandecker","year":"2021","unstructured":"Brandecker S, Hadjiathanasiou A, Kern T, Schuss P, Vatter H, G\u00fcresir E. Primary decompressive craniectomy in poor-grade aneurysmal subarachnoid hemorrhage: long-term outcome in a single-center study and systematic review of literature. Neurosurg Rev. 2021;44:2153\u201362. https:\/\/doi.org\/10.1007\/s10143-020-01383-3.","journal-title":"Neurosurg Rev"},{"key":"2479_CR2","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/s10143-017-0909-x","volume":"41","author":"A Hadjiathanasiou","year":"2018","unstructured":"Hadjiathanasiou A, Schuss P, Ilic I, Borger V, Vatter H, G\u00fcresir E. Decompressive craniectomy for intracerebral haematoma: the influence of additional haematoma evacuation. Neurosurg Rev. 2018;41:649\u201354. https:\/\/doi.org\/10.1007\/s10143-017-0909-x.","journal-title":"Neurosurg Rev"},{"key":"2479_CR3","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/s00701-020-04663-5","volume":"163","author":"C Iaccarino","year":"2021","unstructured":"Iaccarino C, Kolias A, Adelson PD, Rubiano AM, Viaroli E, Buki A, et al. 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Informed consent was waived due to the retrospective study design.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}