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OF was defined as Sequential Organ Failure Assessment (SOFA) score of \u2265\u20093 and MOF as failure of \u2265\u20092 organs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The database revealed 34,469 EMTP, here 37% suffered from OF (16.0%) or MOF (21.0%). Mortality was significantly higher in OF and MOF patients compared to non-OF patients (non-OF: 7.4%; OF: 45.0%; MOF: 59.0%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). 80.9% of all deaths were associated with failure of at least one organ and 51.1% of non-survivors suffered from MOF. Highest odds ratios (OR) for mortality were found for liver (OR: 5.13,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), central nervous system (OR: 3.63,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and renal failure (OR: 3.25,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), followed by cardiovascular (OR: 1.95,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and lung failure (OR: 1.16,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010). Haemostatic failure had no impact on mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OR and mortality differ significantly between distinct OFs due to varying degrees of success in treatment options and systemic impact of these OFs. Clinicians should be aware that OF and MOF occur frequently in EMTP and that these patients have a high risk of dying. Therefore, close screening for and prompt treatment of OF and MOF could be a key strategy to lower mortality of EMTP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00068-026-03240-2","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T09:53:03Z","timestamp":1781517183000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Older age and post-traumatic organ failure a TraumaRegister DGU\u00ae analysis of 34,469 elderly major trauma patients"],"prefix":"10.1007","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1188-4791","authenticated-orcid":false,"given":"Tim Niklas","family":"Bewersdorf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0141-1747","authenticated-orcid":false,"given":"Rolf","family":"Lefering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3563-0283","authenticated-orcid":false,"given":"Stephan","family":"Stein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8903-1621","authenticated-orcid":false,"given":"Jan","family":"Streblow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4083-1311","authenticated-orcid":false,"given":"Sebastian","family":"Findeisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6711-7380","authenticated-orcid":false,"given":"Gerhard","family":"Schmidmaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8953-9384","authenticated-orcid":false,"given":"Tobias","family":"Grossner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"3240_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10071362","author":"J Scherer","year":"2021","unstructured":"Scherer J, Kalbas Y, Ziegenhain F, Neuhaus V, Lefering R, Teuben M, et al. 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Thus, no patient consent was required. The research was conducted in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The Ethics Committee board, Faculty of Medicine, Heidelberg University, Heidelberg, Germany granted a general approval of such de-personalized data (No. S-172\/2025).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The requirement for informed consent was waived due to the register-based study design.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate and publish"}},{"value":"RL declares that his institution (University Witten\/Herdecke) has an ongoing service agreement with AUC GmbH (Akademie der Unfallchirurgie; the owner of the TraumaRegister DGU) which includes the statistical support in registry data analysis. The other authors have no competing interests to declare that are relevant to the content of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"189"}}