{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T11:12:55Z","timestamp":1697541175957},"reference-count":159,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesist"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1007\/s00101-006-1056-x","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T17:56:44Z","timestamp":1152295004000},"page":"1068-1079","source":"Crossref","is-referenced-by-count":9,"title":["Kohlenmonoxid \u2013 Gift oder potenzielles Therapeutikum?"],"prefix":"10.1007","volume":"55","author":[{"given":"A.","family":"Hoetzel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"1056_CR1","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1096\/fj.03-0921fje","volume":"18","author":"Akamatsu","year":"2004","unstructured":"Akamatsu Y, Haga M, Tyagi S et al. (2004) Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury. FASEB J 18: 771\u2013772","journal-title":"FASEB J"},{"key":"1056_CR2","doi-asserted-by":"crossref","first-page":"L1270","DOI":"10.1152\/ajpcell.00153.2003","volume":"285","author":"Ameredes","year":"2003","unstructured":"Ameredes BT, Otterbein LE, Kohut LK et al. (2003) Low-dose carbon monoxide reduces airway hyperresponsiveness in mice. Am J Physiol 285: L1270\u20131276","journal-title":"Am J Physiol"},{"key":"1056_CR3","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1053\/jhep.2002.32467","volume":"35","author":"Amersi","year":"2002","unstructured":"Amersi F, Shen XD, Anselmo D et al. (2002) Ex vivo exposure to carbon monoxide prevents hepatic ischemia\/reperfusion injury through p38 MAP kinase pathway. Hepatology 35: 815\u2013823","journal-title":"Hepatology"},{"key":"1056_CR4","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1001\/archneur.55.6.845","volume":"55","author":"Amitai","year":"1998","unstructured":"Amitai Y, Zlotogorski Z, Golan-Katzav V et al. (1998) Neuropsychological impairment from acute low-level exposure to carbon monoxide. Arch Neurol 55: 845\u2013848","journal-title":"Arch Neurol"},{"key":"1056_CR5","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1136\/thorax.55.2.138","volume":"55","author":"Antuni","year":"2000","unstructured":"Antuni JD, Kharitonov SA, Hughes D et al. (2000) Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis. Thorax 55: 138\u2013142","journal-title":"Thorax"},{"key":"1056_CR6","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1053\/j.gastro.2004.11.061","volume":"128","author":"Arguedas","year":"2005","unstructured":"Arguedas MR, Drake BB, Kapoor A, Fallon MB (2005) Carboxyhemoglobin levels in cirrhotic patients with and without hepatopulmonary syndrome. Gastroenterology 128: 328\u2013333","journal-title":"Gastroenterology"},{"key":"1056_CR7","doi-asserted-by":"crossref","first-page":"18148","DOI":"10.1016\/S0021-9258(19)37165-0","volume":"267","author":"Balla","year":"1992","unstructured":"Balla G, Jacob HS, Balla J et al. (1992) Ferritin: a cytoprotective antioxidant strategem of endothelium. J Biol Chem 267: 18148\u201318153","journal-title":"J Biol Chem"},{"key":"1056_CR8","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1152\/japplphysiol.00760.2004","volume":"98","author":"Bel van","year":"2005","unstructured":"Bel F van, Latour V, Vreman HJ et al. (2005) Is carbon monoxide-mediated cyclic guanosine monophosphate production responsible for low blood pressure in neonatal respiratory distress syndrome? J Appl Physiol 98: 1044\u20131049","journal-title":"J Appl Physiol"},{"key":"1056_CR9","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/01.MIB.0000164017.06538.8a","volume":"11","author":"Berberat","year":"2005","unstructured":"Berberat PO, Rahim YI, Yamashita K et al. (2005) Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis. Inflamm Bowel Dis 11: 350\u2013359","journal-title":"Inflamm Bowel Dis"},{"key":"1056_CR10","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1084\/jem.192.7.1015","volume":"192","author":"Brouard","year":"2000","unstructured":"Brouard S, Otterbein LE, Anrather J et al. (2000) Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med 192: 1015\u20131026","journal-title":"J Exp Med"},{"key":"1056_CR11","doi-asserted-by":"crossref","first-page":"17950","DOI":"10.1074\/jbc.M108317200","volume":"277","author":"Brouard","year":"2002","unstructured":"Brouard S, Berberat PO, Tobiasch E et al. (2002) Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis. J Biol Chem 277: 17950\u201317961","journal-title":"J Biol Chem"},{"key":"1056_CR12","first-page":"497","volume":"32","author":"Brune","year":"1987","unstructured":"Brune B, Ullrich V (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol Pharmacol 32: 497\u2013504","journal-title":"Mol Pharmacol"},{"key":"1056_CR13","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/(SICI)1099-1263(199909\/10)19:5<379::AID-JAT563>3.0.CO;2-8","volume":"19","author":"Burg von","year":"1999","unstructured":"Burg R von (1999) Carbon monoxide. J Appl Toxicol 19: 379\u2013386","journal-title":"J Appl Toxicol"},{"key":"1056_CR14","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1006\/pupt.1998.0152","volume":"11","author":"Cardell","year":"1998","unstructured":"Cardell LO, Lou YP, Takeyama K et al. (1998) Carbon monoxide, a cyclic GMP-related messenger, involved in hypoxic bronchodilation in vivo. Pulm Pharmacol Ther 11: 309\u2013315","journal-title":"Pulm Pharmacol Ther"},{"key":"1056_CR15","first-page":"L806","volume":"278","author":"Carraway","year":"2000","unstructured":"Carraway MS, Ghio AJ, Carter JD, Piantadosi CA (2000) Expression of heme oxygenase-1 in the lung in chronic hypoxia. Am J Physiol 278: L806\u2013812","journal-title":"Am J Physiol"},{"key":"1056_CR16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0272-5231(05)70068-X","volume":"22","author":"Chapman","year":"2001","unstructured":"Chapman JT, Choi AM (2001) Exhaled monoxides as a pulmonary function test: use of exhaled nitric oxide and carbon monoxide. Clin Chest Med 22: 817\u2013836","journal-title":"Clin Chest Med"},{"key":"1056_CR17","first-page":"L209","volume":"281","author":"Chapman","year":"2001","unstructured":"Chapman JT, Otterbein LE, Elias JA, Choi AM (2001) Carbon monoxide attenuates aeroallergen-induced inflammation in mice. Am J Physiol 281: L209\u2013216","journal-title":"Am J Physiol"},{"key":"1056_CR18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1034\/j.1600-6143.2002.20702.x","volume":"2","author":"Chauveau","year":"2002","unstructured":"Chauveau C, Bouchet D, Roussel JC et al. (2002) Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection. Am J Transplant 2: 581\u2013592","journal-title":"Am J Transplant"},{"key":"1056_CR19","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/clc.4960280410","volume":"28","author":"Chen","year":"2005","unstructured":"Chen SM, Li YG, Wang DM (2005) Study on changes of heme oxygenase-1 expression in patients with coronary heart disease. Clin Cardiol 28: 197\u2013201","journal-title":"Clin Cardiol"},{"key":"1056_CR20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ehj.2003.10.009","volume":"25","author":"Chen","year":"2004","unstructured":"Chen YH, Chau LY, Lin MW et al. (2004) Heme oxygenase-1 gene promotor microsatellite polymorphism is associated with angiographic restenosis after coronary stenting. Eur Heart J 25: 39\u201347","journal-title":"Eur Heart J"},{"key":"1056_CR21","first-page":"L949","volume":"281","author":"Clayton","year":"2001","unstructured":"Clayton CE, Carraway MS, Suliman HB et al. (2001) Inhaled carbon monoxide and hyperoxic lung injury in rats. Am J Physiol 281: L949\u2013957","journal-title":"Am J Physiol"},{"key":"1056_CR22","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1172\/JCI104802","volume":"42","author":"Coburn","year":"1963","unstructured":"Coburn RF, Blakemore WS, Forster RE (1963) Endogenous carbon monoxide production in man. J Clin Invest 42: 1172\u20131178","journal-title":"J Clin Invest"},{"key":"1056_CR23","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1172\/JCI105360","volume":"45","author":"Coburn","year":"1966","unstructured":"Coburn RF, Williams WJ, Kahn SB (1966) Endogenous carbon monoxide production in patients with hemolytic anemia. J Clin Invest 45: 460\u2013468","journal-title":"J Clin Invest"},{"key":"1056_CR24","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1161\/01.RES.86.12.1184","volume":"86","author":"Coceani","year":"2000","unstructured":"Coceani F (2000) Carbon monoxide in vasoregulation: the promise and the challenge. Circ Res 86: 1184\u20131186","journal-title":"Circ Res"},{"key":"1056_CR25","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1136\/oem.60.3.212","volume":"60","author":"Deschamps","year":"2003","unstructured":"Deschamps D, Geraud C, Julien H et al. (2003) Memory one month after acute carbon monoxide intoxication: a prospective study. Occup Environ Med 60: 212\u2013216","journal-title":"Occup Environ Med"},{"key":"1056_CR26","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/path.1656","volume":"204","author":"Dijkstra","year":"2004","unstructured":"Dijkstra G, Blokzijl H, Bok L et al. (2004) Opposite effect of oxidative stress on inducible nitric oxide synthase and haem oxygenase-1 expression in intestinal inflammation: anti-inflammatory effect of carbon monoxide. J Pathol 204: 296\u2013303","journal-title":"J Pathol"},{"key":"1056_CR27","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1165\/ajrcmb.24.3.4001","volume":"24","author":"Donnelly","year":"2001","unstructured":"Donnelly LE, Barnes PJ (2001) Expression of heme oxygenase in human airway epithelial cells. Am J Respir Cell Mol Biol 24: 295\u2013303","journal-title":"Am J Respir Cell Mol Biol"},{"key":"1056_CR28","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.cardiores.2004.11.007","volume":"65","author":"Dubuis","year":"2005","unstructured":"Dubuis E, Potier M, Wang R, Vandier C (2005) Continuous inhalation of carbon monoxide attenuates hypoxic pulmonary hypertension development presumably through activation of BKCa channels. Cardiovasc Res 65: 751\u2013761","journal-title":"Cardiovasc Res"},{"key":"1056_CR29","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1093\/jn\/128.12.2295","volume":"128","author":"Eisenstein","year":"1998","unstructured":"Eisenstein RS, Blemings KP (1998) Iron regulatory proteins, iron responsive elements and iron homeostasis. J Nutr 128: 2295\u20132298","journal-title":"J Nutr"},{"key":"1056_CR30","doi-asserted-by":"crossref","first-page":"8567","DOI":"10.1073\/pnas.1431233100","volume":"100","author":"Farrugia","year":"2003","unstructured":"Farrugia G, Lei S, Lin X et al. (2003) A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract. Proc Natl Acad Sci USA 100: 8567\u20138570","journal-title":"Proc Natl Acad Sci USA"},{"key":"1056_CR31","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1002\/hep.510290621","volume":"29","author":"Fernandez","year":"1999","unstructured":"Fernandez M, Bonkovsky HL (1999) Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats. Hepatology 29: 1672\u20131679","journal-title":"Hepatology"},{"key":"1056_CR32","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/10715769900301031","volume":"31","author":"Foresti","year":"1999","unstructured":"Foresti R, Motterlini R (1999) The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis. Free Radic Res 31: 459\u2013475","journal-title":"Free Radic Res"},{"key":"1056_CR33","doi-asserted-by":"crossref","first-page":"18411","DOI":"10.1074\/jbc.272.29.18411","volume":"272","author":"Foresti","year":"1997","unstructured":"Foresti R, Clark JE, Green CJ, Motterlini R (1997) Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions. J Biol Chem 272: 18411\u201318417","journal-title":"J Biol Chem"},{"key":"1056_CR34","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/sj.bjp.0705825","volume":"142","author":"Foresti","year":"2004","unstructured":"Foresti R, Hammad J, Clark JE et al. (2004) Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol 142: 453\u2013460","journal-title":"Br J Pharmacol"},{"key":"1056_CR35","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1161\/01.ATV.0000142364.85911.0e","volume":"24","author":"Fujimoto","year":"2004","unstructured":"Fujimoto H, Ohno M, Ayabe S et al. (2004) Carbon monoxide protects against cardiac ischemia-reperfusion injury in vivo via MAPK and Akt-eNOS pathways. Arterioscler Thromb Vasc Biol 24: 1848\u20131853","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1056_CR36","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/87929","volume":"7","author":"Fujita","year":"2001","unstructured":"Fujita T, Toda K, Karimova A et al. (2001) Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis. Nat Med 7: 598\u2013604","journal-title":"Nat Med"},{"key":"1056_CR37","doi-asserted-by":"crossref","first-page":"L1003","DOI":"10.1152\/ajpcell.00213.2004","volume":"288","author":"Ghosh","year":"2005","unstructured":"Ghosh S, Wilson MR, Choudhury S et al. (2005) Effects of inhaled carbon monoxide on acute lung injury in mice. Am J Physiol 288: L1003\u20131009","journal-title":"Am J Physiol"},{"key":"1056_CR38","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/S0006-291X(03)01504-3","volume":"308","author":"Grosser","year":"2003","unstructured":"Grosser N, Abate A, Oberle S et al. (2003) Heme oxygenase-1 induction may explain the antioxidant profile of aspirin. Biochem Biophys Res Commun 308: 956\u2013960","journal-title":"Biochem Biophys Res Commun"},{"key":"1056_CR39","first-page":"L779","volume":"278","author":"Grover","year":"2000","unstructured":"Grover TR, Rairigh RL, Zenge JP et al. (2000) Inhaled carbon monoxide does not cause pulmonary vasodilation in the late-gestation fetal lamb. Am J Physiol 278: L779\u2013784","journal-title":"Am J Physiol"},{"key":"1056_CR40","doi-asserted-by":"crossref","first-page":"994","DOI":"10.2337\/diabetes.51.4.994","volume":"51","author":"Gunther","year":"2002","unstructured":"Gunther L, Berberat PO, Haga M et al. (2002) Carbon monoxide protects pancreatic beta-cells from apoptosis and improves islet function\/survival after transplantation. Diabetes 51: 994\u2013999","journal-title":"Diabetes"},{"key":"1056_CR41","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1164\/ajrccm.172.6.955","volume":"172","author":"Hampson","year":"2005","unstructured":"Hampson NB, Weaver LK, Piantadosi CA (2005) \u201eLow-level\u201c carbon monoxide administration may carry risk. Am J Respir Crit Care Med 172: 784\u2013785","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR42","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1089\/152308602753666352","volume":"4","author":"Hartsfield","year":"2002","unstructured":"Hartsfield CL (2002) Cross talk between carbon monoxide and nitric oxide. Antioxid Redox Signal 4: 301\u2013307","journal-title":"Antioxid Redox Signal"},{"key":"1056_CR43","first-page":"L980","volume":"273","author":"Hartsfield","year":"1997","unstructured":"Hartsfield CL, Alam J, Cook JL, Choi AMK (1997) Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide. Am J Physiol 273: L980\u2013988","journal-title":"Am J Physiol"},{"key":"1056_CR44","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1213\/01.ANE.0000123821.51802.F3","volume":"99","author":"Hayashi","year":"2004","unstructured":"Hayashi M, Takahashi T, Morimatsu H et al. (2004) Increased carbon monoxide concentration in exhaled air after surgery and anesthesia. Anesth Analg 99: 444\u2013448","journal-title":"Anesth Analg"},{"key":"1056_CR45","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1084\/jem.20051047","volume":"202","author":"Hegazi","year":"2005","unstructured":"Hegazi RA, Rao KN, Mayle A et al. (2005) Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway. J Exp Med 202: 1703\u20131713","journal-title":"J Exp Med"},{"key":"1056_CR46","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1089\/104454902753759726","volume":"21","author":"Hill-Kapturczak","year":"2002","unstructured":"Hill-Kapturczak N, Chang SH, Agarwal A (2002) Heme oxygenase and the kidney. DNA Cell Biol 21: 307\u2013321","journal-title":"DNA Cell Biol"},{"key":"1056_CR47","first-page":"145","volume":"44","author":"Hoetzel","year":"2003","unstructured":"Hoetzel A, Geiger K (2003) Stressproteine: Grundlagen und Bedeutung f\u00fcr die An\u00e4sthesie und Intensivmedizin. Anaesthesiol Intensivmed 44: 145\u2013158","journal-title":"Anaesthesiol Intensivmed"},{"key":"1056_CR48","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1053\/jhep.2001.23431","volume":"33","author":"Hoetzel","year":"2001","unstructured":"Hoetzel A, Vagts DA, Loop T et al. (2001) Effect of nitric oxide on shock-induced hepatic heme oxygenase-1 expression in the rat. Hepatology 33: 925\u2013937","journal-title":"Hepatology"},{"key":"1056_CR49","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1097\/00000542-200211000-00043","volume":"97","author":"Hoetzel","year":"2002","unstructured":"Hoetzel A, Geiger S, Loop T et al. (2002) Differential effects of volatile anesthetics on hepatic heme oxygenase-1 expression in the rat. Anesthesiology 97: 1318\u20131321","journal-title":"Anesthesiology"},{"key":"1056_CR50","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/00000542-200601000-00016","volume":"104","author":"Hoetzel","year":"2006","unstructured":"Hoetzel A, Leitz D, Schmidt R et al. (2006) Mechanism of hepatic heme oxygenase-1 induction by isoflurane. Anesthesiology 104: 101\u2013109","journal-title":"Anesthesiology"},{"key":"1056_CR51","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1136\/thx.53.8.668","volume":"53","author":"Horvath","year":"1998","unstructured":"Horvath I, Donnelly LE, Kiss A et al. (1998) Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress. Thorax 53: 668\u2013672","journal-title":"Thorax"},{"key":"1056_CR52","doi-asserted-by":"crossref","first-page":"9265","DOI":"10.1073\/pnas.84.24.9265","volume":"84","author":"Ignarro","year":"1987","unstructured":"Ignarro LJ, Buga GM, Wood KS et al. (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A 84: 9265\u20139269","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1056_CR53","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.surg.2005.06.015","volume":"138","author":"Kaizu","year":"2005","unstructured":"Kaizu T, Nakao A, Tsung A et al. (2005) Carbon monoxide inhalation ameliorates cold ischemia\/reperfusion injury after rat liver transplantation. Surgery 138: 229\u2013235","journal-title":"Surgery"},{"key":"1056_CR54","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1089\/104303402320138970","volume":"13","author":"Ke","year":"2002","unstructured":"Ke B, Buelow R, Shen XD et al. (2002) Heme oxygenase 1 gene transfer prevents CD95\/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway. Hum Gene Ther 13: 1189\u20131199","journal-title":"Hum Gene Ther"},{"key":"1056_CR55","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1164\/ajrccm.164.10.2106119","volume":"164","author":"Khatri","year":"2001","unstructured":"Khatri SB, Ozkan M, McCarthy K et al. (2001) Alterations in exhaled gas profile during allergen-induced asthmatic response. Am J Respir Crit Care Med 164: 1844\u20131848","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR56","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1146\/annurev.pharmtox.46.120604.141053","volume":"46","author":"Kim","year":"2006","unstructured":"Kim HP, Ryter SW, Choi AM (2006) CO as a cellular signaling molecule. Annu Rev Pharmacol Toxicol 46: 411\u2013449","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"1056_CR57","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S1054-3589(08)61092-3","volume":"34","author":"Kim","year":"1995","unstructured":"Kim YM, Bergonia HA, Muller C et al. (1995) Nitric oxide and intracellular heme. Adv Pharmacol 34: 277\u2013291","journal-title":"Adv Pharmacol"},{"key":"1056_CR58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s004080000043","volume":"179","author":"Kinhult","year":"2001","unstructured":"Kinhult J, Uddman R, Cardell LO (2001) The induction of carbon monoxide-mediated airway relaxation by PACAP 38 in isolated guinea pig airways. Lung 179: 1\u20138","journal-title":"Lung"},{"key":"1056_CR59","first-page":"F563","volume":"290","author":"Kirkby","year":"2006","unstructured":"Kirkby KA, Adin CA (2006) Products of heme oxygenase and their potential therapeutic applications. Am J Physiol 290: F563\u2013571","journal-title":"Am J Physiol"},{"key":"1056_CR60","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1096\/fj.03-0996fje","volume":"18","author":"Lavitrano","year":"2004","unstructured":"Lavitrano M, Smolenski RT, Musumeci A et al. (2004) Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs. FASEB J 18: 1093\u20131095","journal-title":"FASEB J"},{"key":"1056_CR61","doi-asserted-by":"crossref","first-page":"5375","DOI":"10.1074\/jbc.272.9.5375","volume":"272","author":"Lee","year":"1997","unstructured":"Lee PJ, Jiang BH, Chin BY et al. (1997) Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375\u20135381","journal-title":"J Biol Chem"},{"key":"1056_CR62","first-page":"L175","volume":"279","author":"Lee","year":"2000","unstructured":"Lee PJ, Camhi SL, Chin BY et al. (2000) AP-1 and STAT mediate hyperoxia-induced gene transcription of heme oxygenase-1. Am J Physiol 279: L175\u2013182","journal-title":"Am J Physiol"},{"key":"1056_CR63","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nm0302-240","volume":"8","author":"Lee","year":"2002","unstructured":"Lee TS, Chau LY (2002) Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med 8: 240\u2013246","journal-title":"Nat Med"},{"key":"1056_CR64","doi-asserted-by":"crossref","first-page":"3393","DOI":"10.4049\/jimmunol.165.6.3393","volume":"165","author":"Li","year":"2000","unstructured":"Li N, Venkatesan MI, Miguel A et al. (2000) Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element. J Immunol 165: 3393\u20133401","journal-title":"J Immunol"},{"key":"1056_CR65","first-page":"F914","volume":"287","author":"Li","year":"2004","unstructured":"Li P, Jiang H, Yang L et al. (2004) Angiotensin II induces carbon monoxide production in the perfused kidney: relationship to protein kinase C activation. Am J Physiol 287: F914\u2013920","journal-title":"Am J Physiol"},{"key":"1056_CR66","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1164\/ajrccm.162.5.9909081","volume":"162","author":"Lim","year":"2000","unstructured":"Lim S, Groneberg D, Fischer A et al. (2000) Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways: effect of inhaled corticosteroids. Am J Respir Crit Care Med 162: 1912\u20131918","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR67","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S0008-6363(02)00410-8","volume":"55","author":"Liu","year":"2002","unstructured":"Liu XM, Chapman GB, Peyton KJ et al. (2002) Carbon monoxide inhibits apoptosis in vascular smooth muscle cells. Cardiovasc Res 55: 396\u2013405","journal-title":"Cardiovasc Res"},{"key":"1056_CR68","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0021-9258(17)42488-4","volume":"261","author":"Maines","year":"1986","unstructured":"Maines MD, Trakshel GM, Kutty RK (1986) Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem 261: 411\u2013419","journal-title":"J Biol Chem"},{"key":"1056_CR69","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.transproceed.2004.11.079","volume":"37","author":"Martins","year":"2005","unstructured":"Martins PN, Reuzel-Selke A, Jurisch A et al. (2005) Induction of carbon monoxide in the donor reduces graft immunogenicity and chronic graft deterioration. Transplant Proc 37: 379\u2013381","journal-title":"Transplant Proc"},{"key":"1056_CR70","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1164\/rccm.200404-446OC","volume":"171","author":"Mayr","year":"2005","unstructured":"Mayr FB, Spiel A, Leitner J et al. (2005) Effects of carbon monoxide inhalation during experimental endotoxemia in humans. Am J Respir Crit Care Med 171: 354\u2013360","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR71","doi-asserted-by":"crossref","unstructured":"Mazzola S, Forni M, Albertini M et al. (2004) Inhaled carbon monoxide (CO) prevents lung oedema induced by endotoxic shock. Vet Res Commun 28 [Suppl 1]: 209\u2013212","DOI":"10.1023\/B:VERC.0000045408.40400.2e"},{"key":"1056_CR72","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1096\/fj.05-3782fje","volume":"19","author":"Mazzola","year":"2005","unstructured":"Mazzola S, Forni M, Albertini M et al. (2005) Carbon monoxide pretreatment prevents respiratory derangement and ameliorates hyperacute endotoxic shock in pigs. FASEB J 19: 2045\u20132047","journal-title":"FASEB J"},{"key":"1056_CR73","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/j.1432-1033.1997.00725.x","volume":"247","author":"McCoubrey","year":"1997","unstructured":"McCoubrey WK Jr, Huang TJ, Maines MD (1997) Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem 247: 725\u2013732","journal-title":"Eur J Biochem"},{"key":"1056_CR74","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0041-008X(87)90252-3","volume":"87","author":"McFaul","year":"1987","unstructured":"McFaul SJ, McGrath JJ (1987) Studies on the mechanism of carbon monoxide-induced vasodilation in the isolated perfused rat heart. Toxicol Appl Pharmacol 87: 464\u2013473","journal-title":"Toxicol Appl Pharmacol"},{"key":"1056_CR75","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1093\/toxsci\/kfi139","volume":"85","author":"Mirza","year":"2005","unstructured":"Mirza A, Eder V, Rochefort GY et al. (2005) CO inhalation at dose corresponding to tobacco smoke worsens cardiac remodeling after experimental myocardial infarction in rats. Toxicol Sci 85: 976\u2013982","journal-title":"Toxicol Sci"},{"key":"1056_CR76","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1053\/gast.2003.50060","volume":"124","author":"Moore","year":"2003","unstructured":"Moore BA, Otterbein LE, Turler A et al. (2003) Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine. Gastroenterology 124: 377\u2013391","journal-title":"Gastroenterology"},{"key":"1056_CR77","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1097\/01.CCM.0000166349.76514.40","volume":"33","author":"Moore","year":"2005","unstructured":"Moore BA, Overhaus M, Whitcomb J et al. (2005) Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus. Crit Care Med 33: 1317\u20131326","journal-title":"Crit Care Med"},{"key":"1056_CR78","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/00000542-200209000-00025","volume":"97","author":"Morisaki","year":"2002","unstructured":"Morisaki H, Katayama T, Kotake Y et al. (2002) Carbon monoxide modulates endotoxin-induced microvascular leukocyte adhesion through platelet-dependent mechanisms. Anesthesiology 97: 701\u2013709","journal-title":"Anesthesiology"},{"key":"1056_CR79","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.1172\/JCI118334","volume":"96","author":"Morita","year":"1995","unstructured":"Morita T, Kourembanas S (1995) Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide. J Clin Invest 96: 2676\u20132682","journal-title":"J Clin Invest"},{"key":"1056_CR80","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1073\/pnas.92.5.1475","volume":"92","author":"Morita","year":"1995","unstructured":"Morita T, Perrella MA, Lee ME, Kourembanas S (1995) Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 92: 1475\u20131479","journal-title":"Proc Natl Acad Sci USA"},{"key":"1056_CR81","doi-asserted-by":"crossref","first-page":"32804","DOI":"10.1074\/jbc.272.52.32804","volume":"272","author":"Morita","year":"1997","unstructured":"Morita T, Mitsialis SA, Koike H et al. (1997) Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells. J Biol Chem 272: 32804\u201332809","journal-title":"J Biol Chem"},{"key":"1056_CR82","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1164\/rccm.200404-465SO","volume":"172","author":"Morse","year":"2005","unstructured":"Morse D, Choi AM (2005) Heme oxygenase-1: from bench to bedside. Am J Respir Crit Care Med 172: 660\u2013670","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR83","doi-asserted-by":"crossref","first-page":"36993","DOI":"10.1074\/jbc.M302942200","volume":"278","author":"Morse","year":"2003","unstructured":"Morse D, Pischke SE, Zhou Z et al. (2003) Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J Biol Chem 278: 36993\u201336998","journal-title":"J Biol Chem"},{"key":"1056_CR84","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.2174\/1381612033453785","volume":"9","author":"Motterlini","year":"2003","unstructured":"Motterlini R, Mann BE, Johnson TR et al. (2003) Bioactivity and pharmacological actions of carbon monoxide-releasing molecules. Curr Pharm Des 9: 2525\u20132539","journal-title":"Curr Pharm Des"},{"key":"1056_CR85","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1517\/13543784.14.11.1305","volume":"14","author":"Motterlini","year":"2005","unstructured":"Motterlini R, Mann BE, Foresti R et al. (2005) Therapeutic applications of carbon monoxide-releasing molecules. Expert Opin Investig Drugs 14: 1305\u20131318","journal-title":"Expert Opin Investig Drugs"},{"key":"1056_CR86","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1096\/fj.04-2169fje","volume":"19","author":"Motterlini","year":"2005","unstructured":"Motterlini R, Sawle P, Hammad J et al. (2005) CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule. FASEB J 19: 284\u2013286","journal-title":"FASEB J"},{"key":"1056_CR87","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1089\/15270290152608552","volume":"2","author":"Nachar","year":"2001","unstructured":"Nachar RA, Pastene CM, Herrera EA et al. (2001) Low-dose inhaled carbon monoxide reduces pulmonary vascular resistance during acute hypoxemia in adult sheep. High Alt Med Biol 2: 377\u2013385","journal-title":"High Alt Med Biol"},{"key":"1056_CR88","first-page":"H220","volume":"285","author":"Naik","year":"2003","unstructured":"Naik JS, Walker BR (2003) Heme oxygenase-mediated vasodilation involves vascular smooth muscle cell hyperpolarization. Am J Physiol 285: H220\u2013228","journal-title":"Am J Physiol"},{"key":"1056_CR89","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/S0002-9440(10)63515-8","volume":"163","author":"Nakao","year":"2003","unstructured":"Nakao A, Kimizuka K, Stolz DB et al. (2003) Carbon monoxide inhalation protects rat intestinal grafts from ischemia\/reperfusion injury. Am J Pathol 163: 1587\u20131598","journal-title":"Am J Pathol"},{"key":"1056_CR90","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1067\/msy.2003.238","volume":"134","author":"Nakao","year":"2003","unstructured":"Nakao A, Kimizuka K, Stolz DB et al. (2003) Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts. Surgery 134: 285\u2013292","journal-title":"Surgery"},{"key":"1056_CR91","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1136\/gut.52.9.1278","volume":"52","author":"Nakao","year":"2003","unstructured":"Nakao A, Moore BA, Murase N et al. (2003) Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility. Gut 52: 1278\u20131285","journal-title":"Gut"},{"key":"1056_CR92","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1600-6143.2004.00695.x","volume":"5","author":"Nakao","year":"2005","unstructured":"Nakao A, Neto JS, Kanno S et al. (2005) Protection against ischemia\/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant 5: 282\u2013291","journal-title":"Am J Transplant"},{"key":"1056_CR93","first-page":"F979","volume":"287","author":"Neto","year":"2004","unstructured":"Neto JS, Nakao A, Kimizuka K et al. (2004) Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide. Am J Physiol 287: F979\u2013989","journal-title":"Am J Physiol"},{"key":"1056_CR94","first-page":"L268","volume":"289","author":"Ning","year":"2005","unstructured":"Ning W, Choi AM, Li C (2005) Carbon monoxide inhibits IL-17-induced IL-6 production through the MAPK pathway in human pulmonary epithelial cells. Am J Physiol 289: L268\u2013273","journal-title":"Am J Physiol"},{"key":"1056_CR95","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1096\/fj.04-2514fje","volume":"19","author":"Ott","year":"2005","unstructured":"Ott MC, Scott JR, Bihari A et al. (2005) Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia\/reperfusion. FASEB J 19: 106\u2013108","journal-title":"FASEB J"},{"key":"1056_CR96","first-page":"L1029","volume":"279","author":"Otterbein","year":"2000","unstructured":"Otterbein LE, Choi AM (2000) Heme oxygenase: colors of defense against cellular stress. Am J Physiol 279: L1029\u20131037","journal-title":"Am J Physiol"},{"key":"1056_CR97","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1172\/JCI5342","volume":"103","author":"Otterbein","year":"1999","unstructured":"Otterbein LE, Kolls JK, Mantell LL et al. (1999) Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103: 1047\u20131054","journal-title":"J Clin Invest"},{"key":"1056_CR98","first-page":"L688","volume":"276","author":"Otterbein","year":"1999","unstructured":"Otterbein LE, Mantell LL, Choi AM (1999) Carbon monoxide provides protection against hyperoxic lung injury. Am J Physiol 276: L688\u2013694","journal-title":"Am J Physiol"},{"key":"1056_CR99","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/74680","volume":"6","author":"Otterbein","year":"2000","unstructured":"Otterbein LE, Bach FH, Alam J et al. (2000) Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6: 422\u2013428","journal-title":"Nat Med"},{"key":"1056_CR100","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1016\/S0002-9440(10)63610-3","volume":"163","author":"Otterbein","year":"2003","unstructured":"Otterbein LE, Otterbein SL, Ifedigbo E et al. (2003) MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury. Am J Pathol 163: 2555\u20132563","journal-title":"Am J Pathol"},{"key":"1056_CR101","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/nm817","volume":"9","author":"Otterbein","year":"2003","unstructured":"Otterbein LE, Zuckerbraun BS, Haga M et al. (2003) Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med 9: 183\u2013190","journal-title":"Nat Med"},{"key":"1056_CR102","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.4049\/jimmunol.172.8.4744","volume":"172","author":"Pae","year":"2004","unstructured":"Pae HO, Oh GS, Choi BM et al. (2004) Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production. J Immunol 172: 4744\u20134751","journal-title":"J Immunol"},{"key":"1056_CR103","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/327524a0","volume":"327","author":"Palmer","year":"1987","unstructured":"Palmer RM, Ferrige AG, Moncada S (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524\u2013526","journal-title":"Nature"},{"key":"1056_CR104","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1016\/S0024-3205(98)00174-X","volume":"62","author":"Pannen","year":"1998","unstructured":"Pannen BHJ, Bauer M (1998) Differential regulation of hepatic arterial and portal venous vascular resistance by nitric oxide and carbon monoxide in rats. Life Sci 62: 2025\u20132033","journal-title":"Life Sci"},{"key":"1056_CR105","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1172\/JCI3428","volume":"102","author":"Pannen","year":"1998","unstructured":"Pannen BHJ, K\u00f6hler N, Hole B et al. (1998) Protective role of endogenous carbon monoxide in hepatic microcirculatory dysfunction after hemorrhagic shock in rats. J Clin Invest 102: 1220\u20131228","journal-title":"J Clin Invest"},{"key":"1056_CR106","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1183\/09031936.99.13104899","volume":"13","author":"Paredi","year":"1999","unstructured":"Paredi P, Leckie MJ, Horvath I et al. (1999) Changes in exhaled carbon monoxide and nitric oxide levels following allergen challenge in patients with asthma. Eur Respir J 13: 48\u201352","journal-title":"Eur Respir J"},{"key":"1056_CR107","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1152\/jappl.1975.39.4.633","volume":"39","author":"Peterson","year":"1975","unstructured":"Peterson JE, Stewart RD (1975) Predicting the carboxyhemoglobin levels resulting from carbon monoxide exposures. J Appl Physiol 39: 633\u2013638","journal-title":"J Appl Physiol"},{"key":"1056_CR108","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1161\/01.ATV.20.5.1209","volume":"20","author":"Polte","year":"2000","unstructured":"Polte T, Abate A, Dennery PA, Schroder H (2000) Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide. Arterioscler Thromb Vasc Biol 20: 1209\u20131215","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1056_CR109","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1006\/jmcc.1999.0995","volume":"31","author":"Raju","year":"1999","unstructured":"Raju VS, Imai N, Liang CS (1999) Chamber-specific regulation of heme oxygenase-1 (heat shock protein 32) in right-sided congestive heart failure. J Mol Cell Cardiol 31: 1581\u20131589","journal-title":"J Mol Cell Cardiol"},{"key":"1056_CR110","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/0006-2952(89)90347-X","volume":"38","author":"Ramos","year":"1989","unstructured":"Ramos KS, Lin H, McGrath JJ (1989) Modulation of cyclic guanosine monophosphate levels in cultured aortic smooth muscle cells by carbon monoxide. Biochem Pharmacol 38: 1368\u20131370","journal-title":"Biochem Pharmacol"},{"key":"1056_CR111","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1093\/bja\/aei082","volume":"94","author":"Reade","year":"2005","unstructured":"Reade MC, Millo JL, Young JD, Boyd CA (2005) Nitric oxide synthase is downregulated, while haem oxygenase is increased, in patients with septic shock. Br J Anaesth 94: 468\u2013473","journal-title":"Br J Anaesth"},{"key":"1056_CR112","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1152\/physrev.00011.2005","volume":"86","author":"Ryter","year":"2006","unstructured":"Ryter SW, Alam J, Choi AM (2006) Heme oxygenase-1\/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86: 583\u2013650","journal-title":"Physiol Rev"},{"key":"1056_CR113","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1165\/rcmb.4816","volume":"27","author":"Sarady","year":"2002","unstructured":"Sarady JK, Otterbein SL, Liu F et al. (2002) Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages. Am J Respir Cell Mol Biol 27: 739\u2013745","journal-title":"Am J Respir Cell Mol Biol"},{"key":"1056_CR114","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1096\/fj.03-0643fje","volume":"18","author":"Sarady","year":"2004","unstructured":"Sarady JK, Zuckerbraun BS, Bilban M et al. (2004) Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver. FASEB J 18: 854\u2013856","journal-title":"FASEB J"},{"key":"1056_CR115","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1002\/hep.1840380417","volume":"38","author":"Sass","year":"2003","unstructured":"Sass G, Soares MC, Yamashita K et al. (2003) Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice. Hepatology 38: 909\u2013918","journal-title":"Hepatology"},{"key":"1056_CR116","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1002\/hep.20450","volume":"40","author":"Sass","year":"2004","unstructured":"Sass G, Seyfried S, Parreira SM et al. (2004) Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury. Hepatology 40: 1128\u20131135","journal-title":"Hepatology"},{"key":"1056_CR117","doi-asserted-by":"crossref","first-page":"4185","DOI":"10.4049\/jimmunol.166.6.4185","volume":"166","author":"Sato","year":"2001","unstructured":"Sato K, Balla J, Otterbein L et al. (2001) Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol 166: 4185\u20134194","journal-title":"J Immunol"},{"key":"1056_CR118","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jhep.2004.07.004","volume":"41","author":"Schmidt","year":"2004","unstructured":"Schmidt R, Hoetzel A, Baechle T et al. (2004) Isoflurane pretreatment lowers portal venous resistance by increasing hepatic heme oxygenase activity in the rat liver in vivo. J Hepatol 41: 706\u2013713","journal-title":"J Hepatol"},{"key":"1056_CR119","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1089\/152308602753666299","volume":"4","author":"Sethi","year":"2002","unstructured":"Sethi JM, Otterbein LE, Choi AM (2002) Differential modulation by exogenous carbon monoxide of TNF-alpha stimulated mitogen-activated protein kinases in rat pulmonary artery endothelial cells. Antioxid Redox Signal 4: 241\u2013248","journal-title":"Antioxid Redox Signal"},{"key":"1056_CR120","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1136\/adc.88.10.889","volume":"88","author":"Shi","year":"2003","unstructured":"Shi Y, Pan F, Li H et al. (2003) Carbon monoxide concentrations in paediatric sepsis syndrome. Arch Dis Child 88: 889\u2013990","journal-title":"Arch Dis Child"},{"key":"1056_CR121","first-page":"F425","volume":"286","author":"Sikorski","year":"2004","unstructured":"Sikorski EM, Hock T, Hill-Kapturczak N, Agarwal A (2004) The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury. Am J Physiol 286: F425\u2013441","journal-title":"Am J Physiol"},{"key":"1056_CR122","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1748-1716.1951.tb00762.x","volume":"22","author":"Sjostrand","year":"1951","unstructured":"Sjostrand T (1951) Endogenous formation of carbon monoxide; the CO concentration in the inspired and expired air of hospital patients. Acta Physiol Scand 22: 137\u2013141","journal-title":"Acta Physiol Scand"},{"key":"1056_CR123","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.taap.2004.06.027","volume":"201","author":"Slikker","year":"2004","unstructured":"Slikker W Jr, Andersen ME, Bogdanffy MS et al. (2004) Dose-dependent transitions in mechanisms of toxicity: case studies. Toxicol Appl Pharmacol 201: 226\u2013294","journal-title":"Toxicol Appl Pharmacol"},{"key":"1056_CR124","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.4049\/jimmunol.172.6.3553","volume":"172","author":"Soares","year":"2004","unstructured":"Soares MP, Seldon MP, Gregoire IP et al. (2004) Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation. J Immunol 172: 3553\u20133563","journal-title":"J Immunol"},{"key":"1056_CR125","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1165\/rcmb.4851","volume":"27","author":"Song","year":"2002","unstructured":"Song R, Mahidhara RS, Liu F et al. (2002) Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. Am J Respir Cell Mol Biol 27: 603\u2013610","journal-title":"Am J Respir Cell Mol Biol"},{"key":"1056_CR126","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0002-9440(10)63646-2","volume":"163","author":"Song","year":"2003","unstructured":"Song R, Kubo M, Morse D et al. (2003) Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects. Am J Pathol 163: 231\u2013242","journal-title":"Am J Pathol"},{"key":"1056_CR127","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.ejphar.2003.12.026","volume":"486","author":"Stanford","year":"2004","unstructured":"Stanford SJ, Walters MJ, Mitchell JA (2004) Carbon monoxide inhibits endothelin-1 release by human pulmonary artery smooth muscle cells. Eur J Pharmacol 486: 349\u2013352","journal-title":"Eur J Pharmacol"},{"key":"1056_CR128","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.yjmcc.2004.10.006","volume":"38","author":"Stein","year":"2005","unstructured":"Stein AB, Guo Y, Tan W et al. (2005) Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction. J Mol Cell Cardiol 38: 127\u2013134","journal-title":"J Mol Cell Cardiol"},{"key":"1056_CR129","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/jnr.10808","volume":"74","author":"Stockard-Sullivan","year":"2003","unstructured":"Stockard-Sullivan JE, Korsak RA, Webber DS, Edmond J (2003) Mild carbon monoxide exposure and auditory function in the developing rat. J Neurosci Res 74: 644\u2013654","journal-title":"J Neurosci Res"},{"key":"1056_CR130","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1126\/science.3029864","volume":"235","author":"Stocker","year":"1987","unstructured":"Stocker R, Yamamoto Y, McDonagh AF et al. (1987) Bilirubin is an antioxidant of possible physiological importance. Science 235: 1043\u20131046","journal-title":"Science"},{"key":"1056_CR131","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1749-6632.1970.tb49799.x","volume":"174","author":"Stupfel","year":"1970","unstructured":"Stupfel M, Bouley G (1970) Physiological and biochemical effects on rats and mice exposed to small concentrations of carbon monoxide for long periods. Ann N Y Acad Sci 174: 342\u2013368","journal-title":"Ann N Y Acad Sci"},{"key":"1056_CR132","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1172\/JCI118300","volume":"96","author":"Suematsu","year":"1995","unstructured":"Suematsu M, Goda N, Sano T et al. (1995) Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver. J Clin Invest 96: 2431\u20132437","journal-title":"J Clin Invest"},{"key":"1056_CR133","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1089\/ars.2004.6.867","volume":"6","author":"Takahashi","year":"2004","unstructured":"Takahashi T, Morita K, Akagi R, Sassa S (2004) Protective role of heme oxygenase-1 in renal ischemia. Antioxid Redox Signal 6: 867\u2013877","journal-title":"Antioxid Redox Signal"},{"key":"1056_CR134","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1073\/pnas.61.2.748","volume":"61","author":"Tenhunen","year":"1968","unstructured":"Tenhunen R, Marver HS, Schmid R (1968) The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 61: 748\u2013755","journal-title":"Proc Natl Acad Sci USA"},{"key":"1056_CR135","first-page":"H984","volume":"276","author":"Thom","year":"1999","unstructured":"Thom SR, Fisher D, Xu YA et al. (1999) Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat. Am J Physiol 276: H984\u2013992","journal-title":"Am J Physiol"},{"key":"1056_CR136","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1164\/ajrccm.171.11.952","volume":"171","author":"Thom","year":"2005","unstructured":"Thom SR, Weaver LK, Hampson NB (2005) \u201eTherapeutic\u201c carbon monoxide may be toxic. Am J Respir Crit Care Med 171: 1318","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR137","first-page":"F882","volume":"277","author":"Thorup","year":"1999","unstructured":"Thorup C, Jones CL, Gross SS et al. (1999) Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS. Am J Physiol 277: F882\u2013889","journal-title":"Am J Physiol"},{"key":"1056_CR138","first-page":"H623","volume":"278","author":"Togane","year":"2000","unstructured":"Togane Y, Morita T, Suematsu M et al. (2000) Protective roles of endogenous carbon monoxide in neointimal development elicited by arterial injury. Am J Physiol 278: H623\u2013632","journal-title":"Am J Physiol"},{"key":"1056_CR139","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0022-3476(99)70054-5","volume":"135","author":"Uasuf","year":"1999","unstructured":"Uasuf CG, Jatakanon A, James A et al. (1999) Exhaled carbon monoxide in childhood asthma. J Pediatr 135: 569\u2013574","journal-title":"J Pediatr"},{"key":"1056_CR140","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/00003246-200102000-00026","volume":"29","author":"Vassalli","year":"2001","unstructured":"Vassalli F, Pierre S, Julien V et al. (2001) Inhibition of hypoxic pulmonary vasoconstriction by carbon monoxide in dogs. Crit Care Med 29: 359\u2013366","journal-title":"Crit Care Med"},{"key":"1056_CR141","first-page":"601","volume":"48","author":"Vedernikov","year":"1989","unstructured":"Vedernikov YP, Graser T, Vanin AF (1989) Similar endothelium-independent arterial relaxation by carbon monoxide and nitric oxide. Biomed Biochim Acta 48: 601\u2013603","journal-title":"Biomed Biochim Acta"},{"key":"1056_CR142","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1681\/ASN.2004090736","volume":"16","author":"Vera","year":"2005","unstructured":"Vera T, Henegar JR, Drummond HA et al. (2005) Protective effect of carbon monoxide-releasing compounds in ischemia-induced acute renal failure. J Am Soc Nephrol 16: 950\u2013958","journal-title":"J Am Soc Nephrol"},{"key":"1056_CR143","doi-asserted-by":"crossref","unstructured":"Vreman HJ, Wong RJ, Stevenson DK (2000) Carbon monoxide in breath, blood, and other tissues. In: Penney DG (ed) Carbon monoxide poisoning. CRC Press LLC, Boca Raton, pp\u00a019\u201360","DOI":"10.1201\/9781420039320.ch2"},{"key":"1056_CR144","first-page":"G1088","volume":"277","author":"Wakabayashi","year":"1999","unstructured":"Wakabayashi Y, Takamiya R, Mizuki A et al. (1999) Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver. Am J Physiol 277: G1088\u20131096","journal-title":"Am J Physiol"},{"key":"1056_CR145","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.2337\/diabetes.54.5.1400","volume":"54","author":"Wang","year":"2005","unstructured":"Wang H, Lee SS, Gao W et al. (2005) Donor treatment with carbon monoxide can yield islet allograft survival and tolerance. Diabetes 54: 1400\u20131406","journal-title":"Diabetes"},{"key":"1056_CR146","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/153537020322800106","volume":"228","author":"Winestone","year":"2003","unstructured":"Winestone JS, Bonner C, Leffler CW (2003) Carbon monoxide as an attenuator of vasoconstriction in piglet cerebral arterioles. Exp Biol Med 228: 46\u201350","journal-title":"Exp Biol Med"},{"key":"1056_CR147","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/0006-291X(76)90199-6","volume":"73","author":"Wolff","year":"1976","unstructured":"Wolff DG (1976) The formation of carbon monoxide during peroxidation of microsomal lipids. Biochem Biophys Res Commun 73: 850\u2013857","journal-title":"Biochem Biophys Res Commun"},{"key":"1056_CR148","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1124\/pr.57.4.3","volume":"57","author":"Wu","year":"2005","unstructured":"Wu L, Wang R (2005) Carbon monoxide: endogenous production, physiological functions, and pharmacological applications. Pharmacol Rev 57: 585\u2013630","journal-title":"Pharmacol Rev"},{"key":"1056_CR149","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1172\/JCI4165","volume":"103","author":"Yachie","year":"1999","unstructured":"Yachie A, Niida Y, Wada T et al. (1999) Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J Clin Invest 103: 129\u2013135","journal-title":"J Clin Invest"},{"key":"1056_CR150","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1034\/j.1399-3003.1999.13d10.x","volume":"13","author":"Yamaya","year":"1999","unstructured":"Yamaya M, Sekizawa K, Ishizuka S et al. (1999) Exhaled carbon monoxide levels during treatment of acute asthma. Eur Respir J 13: 757\u2013760","journal-title":"Eur Respir J"},{"key":"1056_CR151","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1164\/rccm.200407-914OC","volume":"171","author":"Yasuda","year":"2005","unstructured":"Yasuda H, Yamaya M, Nakayama K et al. (2005) Increased arterial carboxyhemoglobin concentrations in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 171: 1246\u20131251","journal-title":"Am J Respir Crit Care Med"},{"key":"1056_CR152","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1067\/mai.2002.121954","volume":"109","author":"Zanconato","year":"2002","unstructured":"Zanconato S, Scollo M, Zaramella C et al. (2002) Exhaled carbon monoxide levels after a course of oral prednisone in children with asthma exacerbation. J Allergy Clin Immunol 109: 440\u2013445","journal-title":"J Allergy Clin Immunol"},{"key":"1056_CR153","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00134-002-1269-7","volume":"28","author":"Zegdi","year":"2002","unstructured":"Zegdi R, Perrin D, Burdin M et al. (2002) Increased endogenous carbon monoxide production in severe sepsis. Intensive Care Med 28: 793\u2013796","journal-title":"Intensive Care Med"},{"key":"1056_CR154","doi-asserted-by":"crossref","first-page":"22061","DOI":"10.1074\/jbc.M301858200","volume":"278","author":"Zhang","year":"2003","unstructured":"Zhang X, Shan P, Alam J et al. (2003) Carbon monoxide modulates Fas\/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury. J Biol Chem 278: 22061\u201322070","journal-title":"J Biol Chem"},{"key":"1056_CR155","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1074\/jbc.M208419200","volume":"278","author":"Zhang","year":"2003","unstructured":"Zhang X, Shan P, Otterbein LE et al. (2003) Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. J Biol Chem 278: 1248\u20131258","journal-title":"J Biol Chem"},{"key":"1056_CR156","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0002-9440(10)62229-8","volume":"166","author":"Zhou","year":"2005","unstructured":"Zhou Z, Song R, Fattman CL et al. (2005) Carbon monoxide suppresses bleomycin-induced lung fibrosis. Am J Pathol 166: 27\u201337","journal-title":"Am J Pathol"},{"key":"1056_CR157","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1084\/jem.20031003","volume":"198","author":"Zuckerbraun","year":"2003","unstructured":"Zuckerbraun BS, Billiar TR, Otterbein SL et al. (2003) Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. J Exp Med 198: 1707\u20131716","journal-title":"J Exp Med"},{"key":"1056_CR158","first-page":"527","volume":"23","author":"Zuckerbraun","year":"2005","unstructured":"Zuckerbraun BS, McCloskey CA, Gallo D et al. (2005) Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation. Shock 23: 527\u2013532","journal-title":"Shock"},{"key":"1056_CR159","first-page":"G607","volume":"289","author":"Zuckerbraun","year":"2005","unstructured":"Zuckerbraun BS, Otterbein LE, Boyle P et al. (2005) Carbon monoxide protects against the development of experimental necrotizing enterocolitis. Am J Physiol 289: G607\u2013613","journal-title":"Am J Physiol"}],"container-title":["Der Anaesthesist"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-006-1056-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00101-006-1056-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-006-1056-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T10:30:42Z","timestamp":1627554642000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00101-006-1056-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":159,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["1056"],"URL":"https:\/\/doi.org\/10.1007\/s00101-006-1056-x","relation":{},"ISSN":["0003-2417","1432-055X"],"issn-type":[{"value":"0003-2417","type":"print"},{"value":"1432-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}