{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T17:40:17Z","timestamp":1655660417553},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anaesthesist"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s00101-016-0167-2","type":"journal-article","created":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T08:22:11Z","timestamp":1462263731000},"page":"380-390","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pharmakogenetik in An\u00e4sthesie und Intensivmedizin"],"prefix":"10.1007","volume":"65","author":[{"given":"W.","family":"Klingler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Pfenninger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,5,3]]},"reference":[{"key":"167_CR1","volume-title":"Arzneitherapieempfehlungen auf pharmakogenetischer Basis. Habilitationsschrift zur Klinischen Pharmakologie","author":"J Kirchheiner","year":"2004","unstructured":"Kirchheiner J (2004) Arzneitherapieempfehlungen auf pharmakogenetischer Basis. Habilitationsschrift zur Klinischen Pharmakologie. Medizinische Fakult\u00e4t der Charit\u00e9 in Berlin, Berlin"},{"key":"167_CR2","volume-title":"Pharmakogenetik. Stand und Perspektiven. Gutachten im Auftrag des Deutschen Bundestages. B\u00fcro f\u00fcr Technikfolgen-Absch\u00e4tzung beim Deutschen Bundestag (TAB) Hamburg","author":"R Kollek","year":"2005","unstructured":"Kollek R, Dettloff M, Habsguth Ch, Kipke R, Riedel U (2005) Pharmakogenetik. Stand und Perspektiven. Gutachten im Auftrag des Deutschen Bundestages. B\u00fcro f\u00fcr Technikfolgen-Absch\u00e4tzung beim Deutschen Bundestag (TAB) Hamburg. www2.uni-hamburg.de\/fachbereiche-einrichtungen\/fg_ta_med\/forschung\/pharmakogenetik.pdf . Zugegriffen: 24. Jan. 2016"},{"key":"167_CR3","first-page":"503","volume":"56","author":"F Wappler","year":"2015","unstructured":"Wappler F (2015) Orphananesthesia Maligne Hyperthermie. An\u00e4sth Intensivmed 56:503\u2013511","journal-title":"An\u00e4sth Intensivmed"},{"key":"167_CR4","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1007\/s00101-014-2392-x","volume":"63","author":"T Metterlein","year":"2014","unstructured":"Metterlein T, Schuster F, Graf BM, Anetseder M (2014) Maligne Hyperthermie. Anaesthesist 63:908\u2013918","journal-title":"Anaesthesist"},{"key":"167_CR5","volume-title":"Molekulare Humangenetik","author":"T Strachan","year":"2005","unstructured":"Strachan T, Read A (2005) Molekulare Humangenetik. Spektrum Akademischer Verlag, M\u00fcnchen"},{"key":"167_CR6","first-page":"A550","volume":"103","author":"St Aretz","year":"2006","unstructured":"Aretz St, Propping P, N\u00f6then M (2006) Indikationen zur molekulargenetischen Diagnostik bei erblichen Krankheiten. Dtsch \u00c4rztebl 103:A550\u2013558","journal-title":"Dtsch \u00c4rztebl"},{"key":"167_CR7","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1365-2044.2011.06918.x","volume":"67","author":"R Landau","year":"2012","unstructured":"Landau R, Bollag A, Kraft J (2012) Pharmacogenetics and anaesthesia: the value of genetic profiling. Anaesthesia 67:165\u2013179","journal-title":"Anaesthesia"},{"key":"167_CR8","first-page":"470","volume":"4","author":"A Behrooz","year":"2015","unstructured":"Behrooz A (2015) Pharmacogenetics and anaesthetic drugs: implications for perioperative practice annals of medicine and. Surgery 4:470\u2013474","journal-title":"Surgery"},{"key":"167_CR9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1750-1172-9-8","volume":"9","author":"W Klingler","year":"2014","unstructured":"Klingler W, Heiderich S, Girard T, Gravino E, Heffron JJA, Johannsen S, Jurkat-Rott K, R\u00fcffert H, Schuster F, Snoeck M, Tegazzin V, Sorrentino V, Lehmann-Horn F (2014) Functional and genetic characterization of clinical malignant hyperthermia crises: a multi-centre study. Orphanet J Rare Dis 9:8","journal-title":"Orphanet J Rare Dis"},{"key":"167_CR10","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0140-6736(60)92690-8","volume":"2","author":"MA Denborough","year":"1960","unstructured":"Denborough MA, Lovell RRH (1960) Anaesthetic deaths in a family. Lancet 2:45","journal-title":"Lancet"},{"issue":"6258","key":"167_CR11","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/343562a0","volume":"343","author":"T McCarthy","year":"1990","unstructured":"McCarthy T, Healy J, Heffron J, Lehane M, Deufel T, Lehmann-Horn F, Farrall M, Johnson K (1990) Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2. Nature 343(6258):562\u2013564","journal-title":"Nature"},{"key":"167_CR12","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1213\/ANE.0b013e3182937d8b","volume":"118","author":"S Riazi","year":"2014","unstructured":"Riazi S, Larach MG, Hu Ch, Wijeysundera D, Massey Ch, Kraeva N (2014) Malignant Hyperthermia in canada: characteristics of index anesthetics in 129 malignant Hyperthermia susceptible Probands. Anesth Analg 118:381\u2013387","journal-title":"Anesth Analg"},{"key":"167_CR13","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.nmd.2004.10.017","volume":"15","author":"W Klingler","year":"2005","unstructured":"Klingler W, Lehmann-Horn F, Jurkat-Rott K (2005) Complications of anaesthesia in neuromuscular disorders. Neuromuscul Disord 15:195\u2013206","journal-title":"Neuromuscul Disord"},{"key":"167_CR14","first-page":"483","volume":"49","author":"DGAI","year":"2008","unstructured":"DGAI (2008) Empfehlungen zur Therapie der malignen Hyperthermie. An\u00e4sth Intensivmed 49:483\u2013488","journal-title":"An\u00e4sth Intensivmed"},{"key":"167_CR15","unstructured":"Merkblatt der Landes\u00e4rztekammer Baden-W\u00fcrttemberg: \u201eZur \u00e4rztlichen Schweigepflicht\u201c. https:\/\/www.aerztekammer-bw.de\/10aerzte\/40merkblaetter\/10merkblaetter\/schweigepflicht.pdf (Erstellt: Oktober 2009). Zugegriffen: 24. Jan. 2016"},{"key":"167_CR16","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1111\/aas.12126","volume":"57","author":"K Hoppe","year":"2013","unstructured":"Hoppe K, Lehmann-Horn F, Chaiklieng S, Jurkat-Rott K, Adolph O, Klingler W (2013) In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita. Acta Anaesthesiol Scand 57:1017\u20131023","journal-title":"Acta Anaesthesiol Scand"},{"key":"167_CR17","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nature13950","volume":"517","author":"R Zalk","year":"2015","unstructured":"Zalk R, Clark OB, Georges A des, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR (2015) Structure of mammalian ryanodine receptor. Nature 517:44\u201349","journal-title":"Nature"},{"key":"167_CR18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/bja\/aev225","volume":"115","author":"P Hopkins","year":"2015","unstructured":"Hopkins P, Ruffert H, Snoeck M, Girard T, Glahn K, Ellis F, Muller C, Urwyler A, European Malignant Hyperthermia Group collaborators, Gillies R, Glauber V, Heytens L, Islander G, Klingler W, Kraft B, Krivosic-Horber R, Pollock N, Schuster F, Silva H, Sorrentino V, Street N, Tegazzin V, Tzanova I (2015) European Malignant Hyperthermia Group guidelines for investigation of malignant hyperthermia susceptibility. Br J Anaesth 115:531\u2013539","journal-title":"Br J Anaesth"},{"key":"167_CR19","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00424-003-1137-5","volume":"447","author":"A Kuzmenkin","year":"2003","unstructured":"Kuzmenkin A, Jurkat-Rott K, Lehmann-Horn F, Mitrovic N (2003) Impaired slow inactivation due to a benign polymorphism and substitutions of Ser-906 in the II-III loop of the human Nav1.4 channel. Pflugers Arch 447:71\u201377","journal-title":"Pflugers Arch"},{"issue":"1","key":"167_CR20","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1515\/9783110208856.347","volume":"14","author":"Deutscher Bundestag","year":"2009","unstructured":"Deutscher Bundestag (2009) Gesetz \u00fcber genetische Untersuchungen bei Menschen (Gendiagnostikgesetz\u2013GenDG. Jahrb Wissenschaft Ethik 14(1):347\u2013362 (BT Drucksache)","journal-title":"Jahrb Wissenschaft Ethik"},{"key":"167_CR21","first-page":"14","volume":"7","author":"G Satzinger","year":"2006","unstructured":"Satzinger G (2006) Genetische Analysen \u2013 Die Rechtslage in \u00d6sterreich. J\u00a0Neurol Neurochir Psychiatr 7:14\u201318","journal-title":"J Neurol Neurochir Psychiatr"},{"key":"167_CR22","volume-title":"Bundesgesetz \u00fcber genetische Untersuchungen beim Menschen (GUMG) vom 8.Oktober 2004","author":"Der Bundesrat","year":"2014","unstructured":"Der Bundesrat (2014) Bundesgesetz \u00fcber genetische Untersuchungen beim Menschen (GUMG) vom 8.Oktober 2004. https:\/\/www.admin.ch\/opc\/de\/classified-compilation\/20011087\/index.html (Erstellt: 1. Januar 2014). Zugegriffen: 8. M\u00e4rz 2016"},{"key":"167_CR23","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00350-010-2781-3","volume":"28","author":"S Kr\u00f6ger","year":"2010","unstructured":"Kr\u00f6ger S (2010) Das neue Gendiagnostikgesetzt und seine Auswirkungen auf den rechtlichen Rahmen beim Abschluss von Versicherungsvertr\u00e4gen. MedR 28:751\u2013756","journal-title":"MedR"},{"key":"167_CR24","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00101-015-0099-2","volume":"65","author":"B Petersen","year":"2016","unstructured":"Petersen B, Busch T, Meinecke C\u2011D, B\u00f6rge B, Kluba K, Kaisers UX, R\u00fcffert H (2016) Telefonische Anfragen zum Thema maligne Hyperthermie. Anaesthesist 65:36\u201341","journal-title":"Anaesthesist"},{"key":"167_CR25","unstructured":"Informationsblatt der Bayerischen Landes\u00e4rztekammer betreffend die \u201eQualifikation zur fachgebundenen genetischen Beratung\u201c gem\u00e4\u00df GenDG. http:\/\/www.blaek.de\/fortbildung\/Gendiagnostik.pdf . Zugegriffen: 8. M\u00e4rz 2016"}],"container-title":["Der Anaesthesist"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-016-0167-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00101-016-0167-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-016-0167-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T17:00:01Z","timestamp":1655658001000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00101-016-0167-2"}},"subtitle":["Klinische und juristische Herausforderung am Beispiel der Malignen Hyperthermie"],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["167"],"URL":"https:\/\/doi.org\/10.1007\/s00101-016-0167-2","relation":{},"ISSN":["0003-2417","1432-055X"],"issn-type":[{"value":"0003-2417","type":"print"},{"value":"1432-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5]]}}}