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H\u00e4ufig m\u00fcssen Not\u00e4rzte f\u00fcr schmerzgeplagte Patienten nachgefordert werden, wodurch deren Verf\u00fcgbarkeit f\u00fcr z.\u202fB. vitale Notf\u00e4lle reduziert sein kann. Inhalativ zu verabreichende Analgetika k\u00f6nnten hierf\u00fcr eine interessante Alternative darstellen.<\/jats:p><jats:p>Derzeit steht dazu in Deutschland und \u00d6sterreich Lachgas (N<jats:sub>2<\/jats:sub>O, als Livopan\u00ae im Handel) zur Verf\u00fcgung, eine Mischung aus jeweils 50\u202f% Lachgas und Sauerstoff. In \u00d6sterreich ist seit 2018 auch Methoxyfluran (Penthrop\u00ae) zur Behandlung m\u00e4\u00dfiger bis starker Schmerzen nach einem Trauma f\u00fcr die pr\u00e4- und innerklinische Anwendung bei Erwachsenen zugelassen.<\/jats:p><jats:p>In der Zusammenschau der vorhandenen Literatur, jahrzehntelanger Erfahrung in der Anwendung der Sauerstoff-Lachgas-Mischung im angloamerikanischen Bereich und von inhalativem Methoxyfluran v.\u202fa. in Australien sowie aktuellen Studien aus Europa kann gefolgert werden, dass diese bei Einhaltung der Anwendungsvorschriften effektiv, sicher und nebenwirkungsarm sind. Dies best\u00e4tigt auch eine eigene Untersuchung zu Methoxyfluran im pr\u00e4klinischen Einsatz. Die Anwendung von Lachgas ist aufgrund des Druckgaszylinders von der Handhabung her etwas aufwendig; Methoxyfluran ist einfacher anzuwenden und bei starken Schmerzen auch wirksamer. Die Zulassung von Methoxyfluran ist jedoch auf Erwachsene beschr\u00e4nkt, wo es mit zunehmendem Alter deutlich besser wirkt. Der Einsatz von Lachgas und insbesondere Methoxyfluran k\u00f6nnte aufgrund der Datenlage wie auch eigener Erfahrungen f\u00fcr rettungsdienstliches Fachpersonal nach entsprechender Einweisung empfohlen werden.<\/jats:p>","DOI":"10.1007\/s00101-021-01051-1","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T02:51:21Z","timestamp":1634611881000},"page":"233-242","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Volatile An\u00e4sthetika zur pr\u00e4klinischen Analgesie durch Rettungssanit\u00e4ter\u00a0\u2013 Eine \u00dcbersicht","Volatile anesthetics for prehospital analgesia by paramedics\u2014An overview"],"prefix":"10.1007","volume":"71","author":[{"given":"Helmut","family":"Trimmel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Egger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhard","family":"Doppler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Beywinkler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang G.","family":"Voelckel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janett","family":"Kreutziger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"key":"1051_CR1","unstructured":"AGNNW (2019) Penthrox: Einf\u00fchrung auf den deutschen Markt durch Hersteller gestoppt. https:\/\/www.agnnw.de\/?p=4443. 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