{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:28:14Z","timestamp":1787653694717,"version":"build-2736575974"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T00:00:00Z","timestamp":1636329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T00:00:00Z","timestamp":1636329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004869","name":"Westf\u00e4lische Wilhelms-Universit\u00e4t M\u00fcnster","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004869","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anaesthesist"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Die Anzahl postmortal gespendeter Organe ist in Deutschland weit geringer als der Bedarf. Dies unterstreicht die Wichtigkeit einer optimalen Versorgung w\u00e4hrend des gesamten Prozesses der Organspende.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Fragestellung<\/jats:title>\n                <jats:p>Es existieren internationale Leitlinien und nationale Empfehlungen zu intensivmedizinischen organprotektiven Ma\u00dfnahmen beim Organspender. F\u00fcr das an\u00e4sthesiologische Management fehlen evidenzbasierte Empfehlungen. Ziel dieser \u00dcbersichtsarbeit ist es, anhand der vorhandenen Evidenz die pathophysiologischen Ver\u00e4nderungen des irreversiblen Hirnfunktionsausfalls zu rekapitulieren und sich kritisch mit den empfohlenen Behandlungsstrategien und therapeutischen Zielgr\u00f6\u00dfen auseinanderzusetzen. Auch auf ethische Aspekte der Betreuung des postmortalen Organspenders wird eingegangen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methode<\/jats:title>\n                <jats:p>Diese \u00dcbersichtsarbeit basiert auf einer selektiven Literaturrecherche in <jats:italic>PubMed<\/jats:italic> (Suchw\u00f6rter: \u201ebrain dead donor\u201c, \u201eorgan procurement\u201c, \u201eorgan protective therapy\u201c, \u201edonor preconditioning\u201c, \u201eperioperative donor management\u201c, \u201eethical considerations of brain dead donor\u201c). Internationale Leitlinien und nationale Empfehlungen wurden besonders ber\u00fccksichtigt.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Insgesamt ist die Evidenz f\u00fcr optimale intensivmedizinische und perioperative organprotektive Ma\u00dfnahmen beim postmortalen Organspender sehr gering. Nationale und internationale Empfehlungen zu Zielwerten und medikament\u00f6sen Behandlungsstrategien unterscheiden sich teilweise erheblich: kontrollierte randomisierte Studien fehlen. Der Stellenwert einer Narkose zur Explantation bleibt sowohl unter pathophysiologischen Gesichtspunkten als auch aus ethischer Sicht ungekl\u00e4rt.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerungen<\/jats:title>\n                <jats:p>Die Kenntnisse \u00fcber die pathophysiologischen Prozesse im Rahmen des irreversiblen Hirnfunktionsausfalls und die organprotektiven Ma\u00dfnahmen sind ebenso Grundvoraussetzung wie die ethische Auseinandersetzung mit dem Thema postmortale Organspende. Nur dann kann das Behandlungsteam in dieser herausfordernden Situation sowohl dem Organempf\u00e4nger als auch dem Organspender und seinen Angeh\u00f6rigen gerecht werden.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00101-021-01065-9","type":"journal-article","created":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T11:03:44Z","timestamp":1636369424000},"page":"384-391","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Perioperatives Management der postmortalen Organspende","Perioperative management of the brain-dead organ donor"],"prefix":"10.1007","volume":"71","author":[{"given":"Jan S\u00f6nke","family":"Englbrecht","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Lanckohr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Ertmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Zarbock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,8]]},"reference":[{"key":"1065_CR1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1097\/TP.0000000000001848","volume":"102","author":"JA Anesi","year":"2018","unstructured":"Anesi\u00a0JA, Blumberg\u00a0EA, Abbo\u00a0LM (2018) Perioperative antibiotic prophylaxis to prevent surgical site infections in solid organ transplantation. Transplantation 102:21\u201334","journal-title":"Transplantation"},{"key":"1065_CR2","doi-asserted-by":"publisher","first-page":"E361","DOI":"10.1503\/cmaj.190631","volume":"192","author":"IM Ball","year":"2020","unstructured":"Ball\u00a0IM, Hornby\u00a0L, Rochwerg\u00a0B et\u00a0al (2020) Management of the neurologically deceased organ donor: a Canadian clinical practice guideline. CMAJ 192:E361\u2013E369","journal-title":"CMAJ"},{"key":"1065_CR3","doi-asserted-by":"publisher","first-page":"6625955","DOI":"10.1155\/2021\/6625955","volume":"2021","author":"A Bertani","year":"2021","unstructured":"Bertani\u00a0A, Miceli\u00a0V, De Monte\u00a0L et al (2021) Donor preconditioning with inhaled sevoflurane mitigates the effects of ischemia-reperfusion injury in a\u00a0swine model of lung transplantation. Biomed Res Int 2021:6625955","journal-title":"Biomed Res Int"},{"key":"1065_CR4","doi-asserted-by":"publisher","first-page":"195","DOI":"10.2146\/ajhp120568","volume":"70","author":"DW Bratzler","year":"2013","unstructured":"Bratzler\u00a0DW, Dellinger\u00a0EP, Olsen\u00a0KM et\u00a0al (2013) Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 70:195\u2013283","journal-title":"Am J Health Syst Pharm"},{"key":"1065_CR5","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s00063-020-00685-0","volume":"115","author":"FM Brunkhorst","year":"2020","unstructured":"Brunkhorst\u00a0FM, Weigand\u00a0MA, Pletz\u00a0M et al (2020) S3-Leitlinie Sepsis \u2013 Pr\u00e4vention, Diagnose, Therapie und Nachsorge. Med Klin Intensivmed Notfmed 115:37\u2013109","journal-title":"Med Klin Intensivmed Notfmed"},{"key":"1065_CR6","first-page":"A1417","volume":"98","author":"Bundes\u00e4rztekammer","year":"2001","unstructured":"Bundes\u00e4rztekammer (2001) Erkl\u00e4rung zum Hirntod. Dtsch Arztebl 98:A1417","journal-title":"Dtsch Arztebl"},{"key":"1065_CR7","series-title":"Referat \u00d6ffentlichkeitsarbeit Juni 2019","first-page":"1","volume-title":"Gemeinschaftlicher Initiativplan Organspende","author":"Bundesministerium f\u00fcr Gesundheit","year":"2019","unstructured":"Bundesministerium f\u00fcr Gesundheit (2019) Gemeinschaftlicher Initiativplan Organspende. Referat \u00d6ffentlichkeitsarbeit Juni 2019, S\u00a01\u201336"},{"key":"1065_CR8","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/s12871-019-0766-y","volume":"19","author":"B Champigneulle","year":"2019","unstructured":"Champigneulle\u00a0B, Neuschwander\u00a0A, Bronchard\u00a0R et al (2019) Intraoperative management of brain-dead organ donors by anesthesiologists during an organ procurement procedure: results from a\u00a0French survey. BMC Anesthesiol 19:108","journal-title":"BMC Anesthesiol"},{"key":"1065_CR9","doi-asserted-by":"publisher","first-page":"51","DOI":"10.13105\/wjma.v9.i1.51","volume":"9","author":"P Charlier","year":"2021","unstructured":"Charlier\u00a0P, Rebibo\u00a0J\u2011D, Benmoussa\u00a0N (2021) Should we use full analgesic dose of opioids for organ procurement in brainstem dead? World J Meta-Anal 9:51\u201353","journal-title":"World J Meta-Anal"},{"key":"1065_CR10","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/joim.13261","volume":"290","author":"M Christ-Crain","year":"2021","unstructured":"Christ-Crain\u00a0M, Winzeler\u00a0B, Refardt\u00a0J (2021) Diagnosis and management of diabetes insipidus for the internist: an update. J\u00a0Intern Med 290:73\u201387","journal-title":"J Intern Med"},{"key":"1065_CR11","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1097\/CCM.0b013e31823778ee","volume":"40","author":"D De Backer","year":"2012","unstructured":"De Backer\u00a0D, Aldecoa\u00a0C, Njimi\u00a0H, Vincent\u00a0J\u2011L (2012) Dopamine versus norepinephrine in the treatment of septic shock: a\u00a0meta-analysis. Crit Care Med 40:725\u2013730","journal-title":"Crit Care Med"},{"key":"1065_CR12","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1213\/01.ANE.0000153483.61170.0C","volume":"100","author":"SG De Hert","year":"2005","unstructured":"De Hert\u00a0SG, Turani\u00a0F, Mathur\u00a0S, Stowe\u00a0DF (2005) Cardioprotection with volatile anesthetics: mechanisms and clinical implications. Anesth Analg 100:1584\u20131593","journal-title":"Anesth Analg"},{"key":"1065_CR13","volume-title":"Leitfaden f\u00fcr die Organspende","author":"Deutsche Stiftung Organtransplantation","year":"2016","unstructured":"Deutsche Stiftung Organtransplantation (2016) Leitfaden f\u00fcr die Organspende, 4.\u00a0Aufl. DSO, Frankfurt am Main","edition":"4"},{"key":"1065_CR14","series-title":"Newsletter M\u00e4rz","first-page":"4","volume-title":"Verbesserte Transplantatfunktion durch Dopamin","author":"Deutsche Stiftung Organtransplantation","year":"2020","unstructured":"Deutsche Stiftung Organtransplantation (2020) Verbesserte Transplantatfunktion durch Dopamin. Newsletter M\u00e4rz, S\u00a04\u20135"},{"key":"1065_CR15","first-page":"8","volume-title":"Jahresbericht Organspende und Transplantation in Deutschland 2020","author":"Deutsche Stiftung Organtransplantation","year":"2021","unstructured":"Deutsche Stiftung Organtransplantation (2021) Jahresbericht Organspende und Transplantation in Deutschland 2020, S\u00a08\u201311"},{"key":"1065_CR16","volume-title":"Hirntod und Entscheidung zur Organspende Stellungnahme","author":"Deutscher Ethikrat","year":"2015","unstructured":"Deutscher Ethikrat (2015) Hirntod und Entscheidung zur Organspende Stellungnahme. Deutscher Ethikrat, Berlin"},{"key":"1065_CR17","doi-asserted-by":"publisher","first-page":"111.e1","DOI":"10.1016\/j.jcrc.2012.04.015","volume":"28","author":"R Dhar","year":"2013","unstructured":"Dhar\u00a0R, Cotton\u00a0C, Coleman\u00a0J et al (2013) Comparison of high- and low-dose corticosteroid regimens for organ donor management. J\u00a0Crit Care 28:111.e1\u2013111.e7","journal-title":"J Crit Care"},{"key":"1065_CR18","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1093\/bja\/aeu154","volume":"113","author":"S Dupuis","year":"2014","unstructured":"Dupuis\u00a0S, Amiel\u00a0J\u2011A, Desgroseilliers\u00a0M et al (2014) Corticosteroids in the management of brain-dead potential organ donors: a\u00a0systematic review. Br J Anaesth 113:346\u2013359","journal-title":"Br J Anaesth"},{"key":"1065_CR19","first-page":"293","volume":"78","author":"LJ Elkins","year":"2010","unstructured":"Elkins\u00a0LJ (2010) Inhalational anesthesia for organ procurement: potential indications for administering inhalational anesthesia in the brain-dead organ donor. AANA\u00a0J 78:293\u2013299","journal-title":"AANA J"},{"key":"1065_CR20","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.trre.2018.06.001","volume":"32","author":"AC van Erp","year":"2018","unstructured":"van Erp\u00a0AC, van Dullemen\u00a0LFA, Ploeg\u00a0RJ, Leuvenink\u00a0HGD (2018) Systematic review on the treatment of deceased organ donors. Transplant Rev 32:194\u2013206","journal-title":"Transplant Rev"},{"key":"1065_CR21","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1097\/00003643-200312000-00003","volume":"20","author":"RD Fitzgerald","year":"2003","unstructured":"Fitzgerald\u00a0RD, Hieber\u00a0C, Schweitzer\u00a0E et al (2003) Intraoperative catecholamine release in brain-dead organ donors is not suppressed by administration of fentanyl. Eur J Anaesthesiol 20:952\u2013956","journal-title":"Eur J Anaesthesiol"},{"key":"1065_CR22","first-page":"423","volume":"17","author":"DM Follette","year":"1998","unstructured":"Follette\u00a0DM, Rudich\u00a0SM, Babcock\u00a0WD (1998) Improved oxygenation and increased lung donor recovery with high-dose steroid administration after brain death. J\u00a0Heart Lung Transplant 17:423\u2013429","journal-title":"J Heart Lung Transplant"},{"key":"1065_CR23","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1097\/00007890-199211000-00016","volume":"54","author":"HJ Gramm","year":"1992","unstructured":"Gramm\u00a0HJ, Meinhold\u00a0H, Bickel\u00a0U et\u00a0al (1992) Acute endocrine failure after brain death? Transplantation 54:851\u2013857","journal-title":"Transplantation"},{"key":"1065_CR24","first-page":"552","volume":"113","author":"K Hahnenkamp","year":"2016","unstructured":"Hahnenkamp\u00a0K, B\u00f6hler\u00a0K, Wolters\u00a0H et al (2016) Organ-protective intensive care in organ donors. Dtsch Arztebl Int 113:552\u2013558","journal-title":"Dtsch Arztebl Int"},{"key":"1065_CR25","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1097\/00007890-198905000-00016","volume":"47","author":"TA Howlett","year":"1989","unstructured":"Howlett\u00a0TA, Keogh\u00a0AM, Perry\u00a0L et al (1989) Anterior and posterior pituitary function in brain-stem-dead donors. A possible role for hormonal replacement therapy. Transplantation 47:828\u2013834","journal-title":"Transplantation"},{"key":"1065_CR26","doi-asserted-by":"publisher","first-page":"91","DOI":"10.5603\/AIT.2018.0015","volume":"50","author":"G Katznelson","year":"2019","unstructured":"Katznelson\u00a0G, Clarke\u00a0H (2019) Revisiting the anaesthesiologist\u2019s role during organ procurement. Anaesthesiol Intensive Ther 50:91\u201394","journal-title":"Anaesthesiol Intensive Ther"},{"key":"1065_CR27","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1097\/CCM.0000000000000958","volume":"43","author":"RM Kotloff","year":"2015","unstructured":"Kotloff\u00a0RM, Blosser\u00a0S, Fulda\u00a0GJ et\u00a0al (2015) Management of the potential organ donor in the ICU: Society of Critical Care Medicine\/American College of Chest Physicians\/Association of Organ Procurement Organizations consensus statement. Crit Care Med 43:1291\u20131325","journal-title":"Crit Care Med"},{"key":"1065_CR28","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1097\/SLA.0b013e318190e70c","volume":"248","author":"K Kotsch","year":"2008","unstructured":"Kotsch\u00a0K, Ulrich\u00a0F, Reutzel-Selke\u00a0A et al (2008) Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomized controlled trial. Ann Surg 248:1042\u20131050","journal-title":"Ann Surg"},{"key":"1065_CR29","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s00063-018-0516-9","volume":"114","author":"S-O Kuhn","year":"2019","unstructured":"Kuhn\u00a0S\u2011O, Hahnenkamp\u00a0K (2019) Intensivmedizinisches Management des potentiellen Organspenders: Aktuelle Empfehlungen f\u00fcr Erwachsene. Med Klin Intensivmed Notfmed 114:132\u2013138","journal-title":"Med Klin Intensivmed Notfmed"},{"key":"1065_CR30","doi-asserted-by":"publisher","DOI":"10.1097\/ANA.0000000000000683","author":"AV Lele","year":"2021","unstructured":"Lele\u00a0AV, Nair\u00a0BG, Fong\u00a0C et al (2021) Anesthetic management of brain-dead adult and pediatric organ donors: the Harborview Medical Center experience. J\u00a0Neurosurg Anesthesiol. https:\/\/doi.org\/10.1097\/ANA.0000000000000683","journal-title":"J Neurosurg Anesthesiol"},{"key":"1065_CR31","unstructured":"Maysenh\u00f6lder F (2012) Hirntod und entstellte Leichname. Organspende und ihre Kritiker. https:\/\/www.n-tv.de\/wissen\/Organspende-und-ihre-Kritiker-article5653861.html. Zugegriffen: 9. Dez. 2020"},{"key":"1065_CR32","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s00134-019-05551-y","volume":"45","author":"G Meyfroidt","year":"2019","unstructured":"Meyfroidt\u00a0G, Gunst\u00a0J, Martin-Loeches\u00a0I et al (2019) Management of the brain-dead donor in the ICU: general and specific therapy to improve transplantable organ quality. Intensive Care Med 45:343\u2013353","journal-title":"Intensive Care Med"},{"key":"1065_CR33","first-page":"930487","volume":"2012","author":"AF Minou","year":"2012","unstructured":"Minou\u00a0AF, Dzyadzko\u00a0AM, Shcherba\u00a0AE, Rummo\u00a0OO (2012) The influence of pharmacological preconditioning with sevoflurane on incidence of early allograft dysfunction in liver transplant recipients. Anesthesiol Res Pract 2012:930487","journal-title":"Anesthesiol Res Pract"},{"key":"1065_CR34","unstructured":"NHS Blood and Transplant (2021) Donor optimisation: guidance around selecting potential DBD donors. https:\/\/nhsbtdbe.blob.core.windows.net\/umbraco-assets-corp\/4522\/donor-optimisation-extended-care-bundle.pdf. Zugegriffen: 3. Sept. 2021"},{"key":"1065_CR35","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.ccc.2018.11.013","volume":"35","author":"HI Opdam","year":"2019","unstructured":"Opdam\u00a0HI (2019) Hormonal therapy in organ donors. Crit Care Clin 35:389\u2013405","journal-title":"Crit Care Clin"},{"key":"1065_CR36","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1016\/j.amjsurg.2012.05.011","volume":"204","author":"DS Plurad","year":"2012","unstructured":"Plurad\u00a0DS, Bricker\u00a0S, Neville\u00a0A et\u00a0al (2012) Arginine vasopressin significantly increases the rate of successful organ procurement in potential donors. Am J Surg 204:856\u2013860 (discussion 860\u2013861)","journal-title":"Am J Surg"},{"key":"1065_CR37","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1097\/TP.0000000000001059","volume":"100","author":"ME Richmond","year":"2016","unstructured":"Richmond\u00a0ME, Easterwood\u00a0R, Singh\u00a0RK et al (2016) Low-dose donor dopamine is associated with a\u00a0decreased risk of right heart failure in pediatric heart transplant recipients. Transplantation 100:2729\u20132734","journal-title":"Transplantation"},{"key":"1065_CR38","first-page":"A1876","volume":"98","author":"F Schlemmer","year":"2001","unstructured":"Schlemmer\u00a0F (2001) Hirntod: Die Seele lebt. Dtsch Arztebl 98:A1876\u2013A1877","journal-title":"Dtsch Arztebl"},{"key":"1065_CR39","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1001\/jama.2009.1310","volume":"302","author":"P Schnuelle","year":"2009","unstructured":"Schnuelle\u00a0P, Gottmann\u00a0U, Hoeger\u00a0S et\u00a0al (2009) Effects of donor pretreatment with dopamine on graft function after kidney transplantation: a\u00a0randomized controlled trial. JAMA 302:1067\u20131075","journal-title":"JAMA"},{"key":"1065_CR40","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1177\/1089253217749053","volume":"22","author":"MJ Souter","year":"2018","unstructured":"Souter\u00a0MJ, Eidbo\u00a0E, Findlay\u00a0JY et\u00a0al (2018) Organ donor management: part 1. Toward a\u00a0consensus to guide anesthesia services during donation after brain death. Semin Cardiothorac Vasc Anesth 22:211\u2013222","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"1065_CR41","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1097\/00000542-200403000-00035","volume":"100","author":"K Tanaka","year":"2004","unstructured":"Tanaka\u00a0K, Ludwig\u00a0LM, Kersten\u00a0JR et\u00a0al (2004) Mechanisms of cardioprotection by volatile anesthetics. Anesthesiology 100:707\u2013721","journal-title":"Anesthesiology"},{"key":"1065_CR42","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1097\/00000542-199911000-00037","volume":"91","author":"WG Toller","year":"1999","unstructured":"Toller\u00a0WG, Kersten\u00a0JR, Pagel\u00a0PS et\u00a0al (1999) Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs. Anesthesiology 91:1437\u20131446","journal-title":"Anesthesiology"},{"key":"1065_CR43","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.1016\/j.transproceed.2019.01.158","volume":"51","author":"G Tore Altun","year":"2019","unstructured":"Tore Altun\u00a0G, Corman Dincer\u00a0P, Birtan\u00a0D et\u00a0al (2019) Reasons why organs from deceased donors were not accepted for transplantation. Transplant Proc 51:2202\u20132204","journal-title":"Transplant Proc"},{"key":"1065_CR44","first-page":"492","volume":"61","author":"C Tsagogiorgas","year":"2020","unstructured":"Tsagogiorgas\u00a0C, Beck\u00a0G, Ghezel-Ahmadi\u00a0V et al (2020) Neue Wege der Spender-Pr\u00e4konditionierung in der Intensivmedizin \u2013 von Nerven und Botenstoffen. Anasth Intensivmed 61:492\u2013502","journal-title":"Anasth Intensivmed"},{"key":"1065_CR45","doi-asserted-by":"publisher","first-page":"2260","DOI":"10.1016\/j.transproceed.2012.07.019","volume":"44","author":"GA Westphal","year":"2012","unstructured":"Westphal\u00a0GA, Caldeira Filho\u00a0M, Fiorelli\u00a0A et\u00a0al (2012) Guidelines for maintenance of adult patients with brain death and potential for multiple organ donations: the task force of the Brazilian Association of Intensive Medicine the Brazilian Association of Organs Transplantation, and the Transplantation Center of Santa Catarina. Transplant Proc 44:2260\u20132267","journal-title":"Transplant Proc"},{"key":"1065_CR46","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1186\/s13613-020-00787-0","volume":"10","author":"GA Westphal","year":"2020","unstructured":"Westphal\u00a0GA, Robinson\u00a0CC, Cavalcanti\u00a0AB et al (2020) Brazilian guidelines for the management of brain-dead potential organ donors. The task force of the AMIB, ABTO, BRICNet, and the General Coordination of the National Transplant System. Ann Intensive Care 10:169","journal-title":"Ann Intensive Care"},{"key":"1065_CR47","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1046\/j.1365-2044.2000.055002105.x","volume":"55","author":"PJ Young","year":"2000","unstructured":"Young\u00a0PJ, Matta\u00a0BF (2000) Anaesthesia for organ donation in the brainstem dead\u2014why bother? Anaesthesia 55:105\u2013106","journal-title":"Anaesthesia"},{"key":"1065_CR48","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1186\/s13054-019-2673-5","volume":"23","author":"J Zhang","year":"2019","unstructured":"Zhang\u00a0J, Crichton\u00a0S, Dixon\u00a0A et al (2019) Cumulative fluid accumulation is associated with the development of acute kidney injury and non-recovery of renal function: a\u00a0retrospective analysis. Crit Care 23:392","journal-title":"Crit Care"}],"container-title":["Der Anaesthesist"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-021-01065-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00101-021-01065-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-021-01065-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T10:06:54Z","timestamp":1651658814000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00101-021-01065-9"}},"subtitle":["An\u00e4sthesie zwischen Ethik und Evidenz","Anesthesia between ethics and evidence"],"short-title":[],"issued":{"date-parts":[[2021,11,8]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["1065"],"URL":"https:\/\/doi.org\/10.1007\/s00101-021-01065-9","relation":{},"ISSN":["0003-2417","1432-055X"],"issn-type":[{"value":"0003-2417","type":"print"},{"value":"1432-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,8]]},"assertion":[{"value":"18 October 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"J.\u00a0S.\u00a0Englbrecht, C.\u00a0Lanckohr, C.\u00a0Ertmer und A.\u00a0Zarbock geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}