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Fast t\u00e4glich werden neue Erkenntnisse zu Diagnostik, Klinik und Therapie der Erkrankung publiziert. Dieser Fallbericht beschreibt den letalen Krankheitsverlauf eines 81-j\u00e4hrigen Patienten ohne pulmonale Vorerkrankungen, der als Komplikation der COVID-19-Pneumonie unter nichtinvasiver High-Flow-Sauerstofftherapie eine Riesenbulla entwickelte. Pathophysiologisch kommen\/kommt eine virusbedingte diffuse Zerst\u00f6rung des Alveolargewebes und\/oder die \u201epatient self-inflicted lung injury\u201c in Betracht.<\/jats:p>","DOI":"10.1007\/s00101-021-01072-w","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T21:02:30Z","timestamp":1637614950000},"page":"303-306","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Entwicklung einer Riesenbulla unter Spontanatmung durch \u201epatient self-inflicted lung injury\u201c bei COVID-19-Pneumonie"],"prefix":"10.1007","volume":"71","author":[{"given":"Nicholas","family":"Moellhoff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Groene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludwig","family":"Ney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Hauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"1072_CR1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-237455","author":"S Berhane","year":"2020","unstructured":"Berhane S, Tabor A, Sahu A et al (2020) Development of bullous lung disease in a\u00a0patient with severe COVID-19 pneumonitis. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patienten zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}