{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:03:46Z","timestamp":1789153426828,"version":"build-2803163510"},"reference-count":4,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Bonn"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anaesthesiologie"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die aktualisierte Leitlinie der ESAIC zum postoperativen Delir (POD) umfasst insgesamt 13 Empfehlungen, darunter f\u00fcnf mit dem Empfehlungsgrad \u201estark\u201c: 1.)\u00a0Die Erfassung der pr\u00e4operativen POD-Risikofaktoren, 2.)\u00a0die Optimierung des pr\u00e4operativen Zustands, 3.)\u00a0die Besprechung von Pr\u00e4ventionsstrategien, 4.)\u00a0die Durchf\u00fchrung einer nicht-pharmakologischen Multikomponenten-Intervention bei POD-Risikopatienten und 5.)\u00a0die Nutzen-Risiko-Abw\u00e4gung bei der prophylaktischen Gabe von Dexmedetomidin. Letzteres gilt insbesondere auf Grund der teils widerspr\u00fcchlichen Datenlage und unterschiedlicher Einsatzgebiete (herzchirurgische versus nicht-herzchirurgische Patienten). Weiterhin wird die indexbasierte EEG-\u00dcberwachung der Narkosetiefe empfohlen, wobei auch weitere Parameter, wie die Burst Suppression und das Density Spectral Array mit einbezogen werden sollten. Wenn nicht-pharmakologische Ma\u00dfnahmen versagen, sollte das POD mit Haloperidol therapiert werden. Hingegen wird der Einsatz von Benzodiazepinen nicht empfohlen.<\/jats:p>","DOI":"10.1007\/s00101-024-01404-6","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T12:02:31Z","timestamp":1713787351000},"page":"376-378","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Aktualisierte ESAIC-Leitlinie zum postoperativen Delir beim Erwachsenen","Updated ESAIC guidelines on postoperative delirium in adults"],"prefix":"10.1007","volume":"73","author":[{"given":"Martin","family":"S\u00f6hle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Coburn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"1404_CR1","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1097\/EJA.0000000000000594","volume":"34","author":"C Aldecoa","year":"2017","unstructured":"Aldecoa C, Bettelli G, Bilotta F et al (2017) European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium. Eur J Anaesthesiol 34:192\u2013214","journal-title":"Eur J Anaesthesiol"},{"key":"1404_CR2","unstructured":"Bundesinstitut f\u00fcr Arzneimittel und Medizinprodukte (2022) Rote-Hand-Brief zu Dexmedetomidin: Risiko von erh\u00f6hter Mortalit\u00e4t bei Intensivpatienten \u2264\u202f65\u00a0Jahren. Abgerufen am 13. M\u00e4rz 2024 unter https:\/\/www.bfarm.de\/SharedDocs\/Risikoinformationen\/Pharmakovigilanz\/DE\/RHB\/2022\/rhb-dexmedetomidin.html"},{"key":"1404_CR3","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1097\/EJA.0000000000001876","volume":"41","author":"C Aldecoa","year":"2024","unstructured":"Aldecoa\u00a0C, Bettelli\u00a0G, Bilotta\u00a0F et\u00a0al (2024) Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients. Eur J Anaesthesiol 41:81\u2013108","journal-title":"Eur J Anaesthesiol"},{"key":"1404_CR4","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1007\/s00134-021-06356-8","volume":"47","author":"Y Shehabi","year":"2021","unstructured":"Shehabi\u00a0Y, Neto\u00a0A, Howe\u00a0B et\u00a0al (2021) Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial. Intensive Care Med 47:455\u2013466","journal-title":"Intensive Care Med"}],"container-title":["Die Anaesthesiologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-024-01404-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00101-024-01404-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-024-01404-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T12:02:25Z","timestamp":1718020945000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00101-024-01404-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,22]]},"references-count":4,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1404"],"URL":"https:\/\/doi.org\/10.1007\/s00101-024-01404-6","relation":{},"ISSN":["2731-6858","2731-6866"],"issn-type":[{"value":"2731-6858","type":"print"},{"value":"2731-6866","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,22]]},"assertion":[{"value":"18 March 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"M.\u00a0S\u00f6hle und M.\u00a0Coburn geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}